BRPI0520610A2 - formulação de comprimido de medicamento para alìvio de dor - Google Patents
formulação de comprimido de medicamento para alìvio de dorInfo
- Publication number
- BRPI0520610A2 BRPI0520610A2 BRPI0520610-3A BRPI0520610A BRPI0520610A2 BR PI0520610 A2 BRPI0520610 A2 BR PI0520610A2 BR PI0520610 A BRPI0520610 A BR PI0520610A BR PI0520610 A2 BRPI0520610 A2 BR PI0520610A2
- Authority
- BR
- Brazil
- Prior art keywords
- medicament
- dust
- pain relief
- tablet formulation
- formulation
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 5
- 239000007916 tablet composition Substances 0.000 title abstract 2
- 239000000428 dust Substances 0.000 abstract 3
- 239000000843 powder Substances 0.000 abstract 3
- 229920001685 Amylomaize Polymers 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 238000010410 dusting Methods 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
FORMULAçãO DE COMPRIMIDO DE MEDICAMENTO PARA ALìVIO DE DOR. Uma formulação de comprimido para alivio de dor para a administração oral de um medicamento o qual é feito de uma combinação comprimida de ao menos três pós ou polvilhos secos incluindo um pó ou polvilho de um medicamento; um pó ou polvilho de uma matriz para a liberação do medicamento de alívio; e um pó ou polvilho de ao menos um eletrólito. A matriz de liberação do medicamento de alívio consistindo de um amido de alta amilose não ligado transversalmente, onde o amido de alta amilose é substituído por ao menos um substituinte orgânico compreendendo de ao menos um grupo carboxila. O substituinte orgânico é preferivelmente uma carboxialquila tendo de 2 à 4 átomos de carbono, seus sais ou a mistura dos mesmos. Esse comprimido tem a vantagem de ter uma aperfeiçoada integridade.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002491665A CA2491665A1 (fr) | 2004-12-24 | 2004-12-24 | Formulation de comprime pour liberation soutenue de principe actif |
| PCT/CA2005/001934 WO2006066399A1 (en) | 2004-12-24 | 2005-12-20 | Tablet formulation for sustained drug-release |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0520610A2 true BRPI0520610A2 (pt) | 2009-10-06 |
Family
ID=36601318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0520610-3A BRPI0520610A2 (pt) | 2004-12-24 | 2005-12-20 | formulação de comprimido de medicamento para alìvio de dor |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090011014A1 (pt) |
| EP (1) | EP1833468A1 (pt) |
| JP (1) | JP2008525322A (pt) |
| KR (1) | KR20070094009A (pt) |
| CN (1) | CN101087595A (pt) |
| AU (1) | AU2005318827A1 (pt) |
| BR (1) | BRPI0520610A2 (pt) |
| CA (1) | CA2491665A1 (pt) |
| IL (1) | IL184067A0 (pt) |
| WO (1) | WO2006066399A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5547966B2 (ja) * | 2006-12-15 | 2014-07-16 | カンピナ ネーデルランド ホールディング ビー.ブイ. | 持続放出用の賦形剤及びその使用 |
| EP1935411A1 (en) | 2006-12-15 | 2008-06-25 | Campina Nederland Holding B.V. | Slow release excipient and its use |
| CA2590821A1 (en) * | 2007-06-07 | 2008-12-07 | Universite De Montreal | High-amylose sodium carboxymethyl starch sustained release excipient and process for preparing the same |
| EP2415460A1 (de) * | 2010-08-03 | 2012-02-08 | ratiopharm GmbH | Orale Darreichungsform von Pregabalin |
| US20130338121A1 (en) * | 2011-03-01 | 2013-12-19 | Le Tien Canh | Two speed monolithic system for controlled release of drugs |
| CN103305748A (zh) | 2012-03-15 | 2013-09-18 | 宝山钢铁股份有限公司 | 一种无取向电工钢板及其制造方法 |
| GB201622024D0 (en) | 2016-11-14 | 2017-02-08 | Inventage Lab Inc | Apparatus and method for large scale production of monodisperse, microsheric and biodegradable polymer-based drug delivery |
| KR20200013170A (ko) | 2018-07-20 | 2020-02-06 | 주식회사 코아팜바이오 | 약물 방출 제어 구조를 포함하는 정제 및 3d 프린트 기술을 이용한 정제 제조방법 |
| CN111198246B (zh) * | 2018-11-19 | 2022-07-15 | 上海梅山钢铁股份有限公司 | 一种烧结脱硫脱硝灰中碳酸钙含量的检测方法 |
| CN110200947A (zh) * | 2019-06-27 | 2019-09-06 | 深圳市泛谷药业股份有限公司 | 一种安非他酮肠溶缓释微丸胶囊及其制备方法 |
| CN115317459B (zh) * | 2022-09-05 | 2023-10-31 | 安徽金太阳生化药业有限公司 | 一种氯霉素片的制备工艺 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3034911A (en) * | 1959-03-25 | 1962-05-15 | Nat Starch Chem Corp | Tablet disintegrants |
| US3490742A (en) * | 1966-01-14 | 1970-01-20 | Staley Mfg Co A E | Compressed tablets |
| US3622677A (en) * | 1969-07-07 | 1971-11-23 | Staley Mfg Co A E | Compressed tablets containing compacted starch as binder-disintegrant ingredient |
| US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
| US4369308A (en) * | 1981-07-24 | 1983-01-18 | National Starch And Chemical Corporation | Low swelling starches as tablet disintegrants |
| US4904476A (en) * | 1986-03-04 | 1990-02-27 | American Home Products Corporation | Formulations providing three distinct releases |
| GB8812490D0 (en) * | 1988-05-26 | 1988-06-29 | Agricultural & Food Res | Delayed release formulations |
| GB8820353D0 (en) * | 1988-08-26 | 1988-09-28 | Staniforth J N | Controlled release tablet |
| US5468286A (en) * | 1989-10-25 | 1995-11-21 | National Starch And Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
| EP0475482B1 (en) * | 1990-09-13 | 1994-10-05 | Akzo Nobel N.V. | Stabilized solid chemical compositions |
| CA2041774C (en) * | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Use of cross-linked amylose as a matrix for the slow release of biologically active compounds |
| US5603956A (en) * | 1990-11-27 | 1997-02-18 | Labopharm Inc. | Cross-linked enzymatically controlled drug release |
| US5616343A (en) * | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
| JP4072597B2 (ja) * | 1994-12-27 | 2008-04-09 | ナムローゼ・フェンノートシャップ・オルガノン | 持続性製剤 |
| US5888534A (en) * | 1995-06-13 | 1999-03-30 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| CA2173818A1 (fr) * | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
| DE19640062B4 (de) * | 1996-09-28 | 2006-04-27 | Lts Lohmann Therapie-Systeme Ag | Orale Zubereitung, enthaltend in einer in wässrigem Medium quellbaren Matrix wenigstens einen pharmazeutischen Wirkstoff |
| US5879707A (en) * | 1996-10-30 | 1999-03-09 | Universite De Montreal | Substituted amylose as a matrix for sustained drug release |
| US5807575A (en) * | 1997-02-14 | 1998-09-15 | Rougier Inc. | Manufacture of cross-linked amylose useful as a excipient for control release of active compounds |
| US6284273B1 (en) * | 1998-02-24 | 2001-09-04 | Vincent Lenaerts | Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds |
| IT1318597B1 (it) * | 2000-06-23 | 2003-08-27 | A C R Applied Coating Res S A | Uso di un amido ad alto contenuto di amilosio acetilato epregelatinizzato. |
| US6607748B1 (en) * | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
| MXPA05004410A (es) * | 2002-10-25 | 2005-11-23 | Labopharm Inc | Composiciones de liberacion controlada. |
-
2004
- 2004-12-24 CA CA002491665A patent/CA2491665A1/fr not_active Abandoned
-
2005
- 2005-12-20 US US11/793,994 patent/US20090011014A1/en not_active Abandoned
- 2005-12-20 KR KR1020077016954A patent/KR20070094009A/ko not_active Withdrawn
- 2005-12-20 EP EP05820905A patent/EP1833468A1/en not_active Withdrawn
- 2005-12-20 JP JP2007547121A patent/JP2008525322A/ja active Pending
- 2005-12-20 BR BRPI0520610-3A patent/BRPI0520610A2/pt not_active IP Right Cessation
- 2005-12-20 WO PCT/CA2005/001934 patent/WO2006066399A1/en not_active Ceased
- 2005-12-20 AU AU2005318827A patent/AU2005318827A1/en not_active Abandoned
- 2005-12-20 CN CNA2005800444815A patent/CN101087595A/zh active Pending
-
2007
- 2007-06-19 IL IL184067A patent/IL184067A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2491665A1 (fr) | 2006-06-24 |
| KR20070094009A (ko) | 2007-09-19 |
| EP1833468A1 (en) | 2007-09-19 |
| JP2008525322A (ja) | 2008-07-17 |
| AU2005318827A1 (en) | 2006-06-29 |
| US20090011014A1 (en) | 2009-01-08 |
| WO2006066399A1 (en) | 2006-06-29 |
| CN101087595A (zh) | 2007-12-12 |
| IL184067A0 (en) | 2007-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO EM SUA FORMA AUTENTICADA; OU SEGUNDO PARECER DA PROCURADORIA NO 074/93, DEVE CONSTAR UMA DECLARACAO DE VERACIDADE, A QUAL DEVE SER ASSINADA POR UMA PESSOA DEVIDAMENTE AUTORIZADA A REPRESENTAR O INTERESSADO, DEVENDO A MESMA CONSTAR NO INSTRUMENTO DE PROCURACAO, OU NO SEU SUBSTABELECIMENTO. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |