BRPI0602430A - composição medicinal, inalador para composição medicinal, método de tratamento de um mamìfero, recipiente do tipo capaz de conter a pressão de vapor de um propelente contido em seu interior e adicionalmente contendo uma composição medicinal adequada para administração a um mamìfero, método de produzir uma formulação aerossol adequada para transferência aos pulmões de um mamìfero por inalação - Google Patents

composição medicinal, inalador para composição medicinal, método de tratamento de um mamìfero, recipiente do tipo capaz de conter a pressão de vapor de um propelente contido em seu interior e adicionalmente contendo uma composição medicinal adequada para administração a um mamìfero, método de produzir uma formulação aerossol adequada para transferência aos pulmões de um mamìfero por inalação

Info

Publication number
BRPI0602430A
BRPI0602430A BRPI0602430-0A BRPI0602430A BRPI0602430A BR PI0602430 A BRPI0602430 A BR PI0602430A BR PI0602430 A BRPI0602430 A BR PI0602430A BR PI0602430 A BRPI0602430 A BR PI0602430A
Authority
BR
Brazil
Prior art keywords
mammal
medicinal composition
inhaler
inhalation
transfer
Prior art date
Application number
BRPI0602430-0A
Other languages
English (en)
Inventor
Gary M Knopeck
Jeremy Diringer
Louis Herena
Rajiv R Singh
Original Assignee
Honeywell Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Honeywell Int Inc filed Critical Honeywell Int Inc
Publication of BRPI0602430A publication Critical patent/BRPI0602430A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSIçãO MEDICINAL, INALADOR PARA COMPOSIçãO MEDICINAL,MéTODO DE TRATAMENTO DE UM MAMìFERO, RECIPIENTE DO TIPO CAPAZ DE CONTER A PRESSãO DE VAPOR DE UM PROPELENTE CINTIDO EM SEU INTERIOR E ADICIONAMENTE CONTENDO UMA COMPOSIçãO MEDICINAL ADEQUADA PAR ADMINISTRAçãO A UM MAMìFERO, MéTODO DE PRODUZIR UMA FORMULAçãO AEROSSOL ADEQUADA PARA TRANSFERêNCIA AOS PULMõES DE UM MAMìFERO POR INALAçãO São reveladas composições medicinais, e dispositivos, métodos e sistemas os quais utilizam os mesmos, que compreendem um propelente e pelo menos um composto medicinalmente ativo, o referido propelente compreendendo pelo menos uma fluorolefina possuindo pelo menos dois mas menos que sete átomos de carbono.
BRPI0602430-0A 2005-03-16 2006-03-16 composição medicinal, inalador para composição medicinal, método de tratamento de um mamìfero, recipiente do tipo capaz de conter a pressão de vapor de um propelente contido em seu interior e adicionalmente contendo uma composição medicinal adequada para administração a um mamìfero, método de produzir uma formulação aerossol adequada para transferência aos pulmões de um mamìfero por inalação BRPI0602430A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66257905P 2005-03-16 2005-03-16

Publications (1)

Publication Number Publication Date
BRPI0602430A true BRPI0602430A (pt) 2007-08-14

Family

ID=38336780

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0602430-0A BRPI0602430A (pt) 2005-03-16 2006-03-16 composição medicinal, inalador para composição medicinal, método de tratamento de um mamìfero, recipiente do tipo capaz de conter a pressão de vapor de um propelente contido em seu interior e adicionalmente contendo uma composição medicinal adequada para administração a um mamìfero, método de produzir uma formulação aerossol adequada para transferência aos pulmões de um mamìfero por inalação

Country Status (3)

Country Link
US (5) US9308199B2 (pt)
JP (2) JP2013151503A (pt)
BR (1) BRPI0602430A (pt)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080292564A1 (en) * 2002-10-25 2008-11-27 Honeywell International, Inc. Aerosol compositions containing fluorine substituted olefins and methods and systems using same
US7563936B2 (en) * 2006-10-27 2009-07-21 Honeywell International Inc Processes for geometric isomerization of halogenated olefins
US8008244B2 (en) * 2004-04-29 2011-08-30 Honeywell International Inc. Compositions of tetrafluoropropene and hydrocarbons
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
BRPI0614548A2 (pt) * 2005-08-08 2011-03-29 Novartis Ag embalagem isolada para inaladores de dose medida
US8535556B2 (en) * 2006-03-30 2013-09-17 E I Du Pont De Nemours And Company Compositions comprising iodotrifluoromethane and stabilizers
US8097181B2 (en) * 2006-09-01 2012-01-17 E.I. Du Pont De Nemours And Company Ascorbic acid, terephthalate and nitromethane stabilizers for fluoroolefins
WO2008027594A2 (en) * 2006-09-01 2008-03-06 E. I. Du Pont De Nemours And Company Phenol stabilizers for fluoroolefins
CN101522597B (zh) 2006-10-03 2013-05-29 墨西哥化学阿玛科股份有限公司 通过脱卤化氢制备c3-c6(氢)氟烯烃的方法
GB0706978D0 (en) 2007-04-11 2007-05-16 Ineos Fluor Holdings Ltd Process
US8114828B2 (en) * 2007-04-16 2012-02-14 Honeywell International Inc. Azeotrope-like compositions of tetrafluoropropene and alcohols
MX2010002471A (es) * 2007-09-06 2010-03-26 Du Pont Composiciones azeotropicas y similares a azeotropos de e-1,1,1,4,4,5,5,5-octafluoro-2-penteno.
US7438825B1 (en) * 2008-03-07 2008-10-21 Arkema Inc. Azeotrope-like composition of 1,1,1-trifluoro-3-chloropropene and dimethoxymethane
US7442321B1 (en) 2008-03-07 2008-10-28 Arkema Inc. Azeotrope-like composition of 1,1,1-trifluoro-3-chloropropene and trans-1,2-dichloroethylene
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
PT2435025T (pt) * 2009-05-29 2016-11-11 Pearl Therapeutics Inc Administração, por via respiratória, de agentes activos
FR2954342B1 (fr) 2009-12-18 2012-03-16 Arkema France Fluides de transfert de chaleur a inflammabilite reduite
SG184430A1 (en) * 2010-04-15 2012-11-29 Biota Scient Management Compound for treatment of respiratory condition or disease
FR2959998B1 (fr) 2010-05-11 2012-06-01 Arkema France Fluides de transfert de chaleur ternaires comprenant du difluoromethane, du pentafluoroethane et du tetrafluoropropene
AU2011262781B2 (en) * 2010-06-11 2014-09-25 Daizo Corporation Aerosol composition
IT1406472B1 (it) 2010-12-22 2014-02-28 Nuovo Pignone Spa Prova per similitudine di prestazione di compressore
US8827122B2 (en) * 2011-04-15 2014-09-09 The Clorox Company Non-flammable plastic aerosol
EP2773324A4 (en) * 2011-11-03 2015-07-01 Prec Dermatology Inc STABLE DERMATOLOGICAL AEROSOL FOAMS USING REACTIVE PROPELLERS
TW201412965A (zh) * 2012-08-23 2014-04-01 Du Pont 含四氟丙烯、二氟甲烷、及可選擇地含二氟乙烷的冷媒混合物及其運用
US9554982B2 (en) 2012-09-14 2017-01-31 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
FR2998302B1 (fr) 2012-11-20 2015-01-23 Arkema France Composition refrigerante
JP6454323B2 (ja) 2013-03-15 2019-01-16 パール セラピューティクス，インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム
WO2015006639A1 (en) * 2013-07-12 2015-01-15 SILVA, John, H. Mouthpiece for inhalers
US20150023886A1 (en) 2013-07-16 2015-01-22 The Procter & Gamble Company Antiperspirant Spray Devices and Compositions
US11186424B2 (en) 2013-07-16 2021-11-30 The Procter & Gamble Company Antiperspirant spray devices and compositions
FR3010415B1 (fr) 2013-09-11 2015-08-21 Arkema France Fluides de transfert de chaleur comprenant du difluoromethane, du pentafluoroethane, du tetrafluoropropene et eventuellement du propane
US9579265B2 (en) 2014-03-13 2017-02-28 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
WO2015137952A1 (en) 2014-03-13 2015-09-17 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
GB2537639B (en) * 2015-04-21 2020-09-23 Consort Medical Plc Medicament delivery device
GB2537638A (en) * 2015-04-21 2016-10-26 Consort Medical Plc Medicament delivery device
CA162808S (en) * 2015-06-03 2016-01-07 Smart Rs Inc Adaptor for inhaled medication delivery
EP3436115B1 (en) * 2016-03-31 2021-07-28 Chiesi Farmaceutici S.p.A. Aerosol inhalation device
GB201615209D0 (en) 2016-09-07 2016-10-19 Mexichem Fluor Sa De Cv Catalyst and process using the catalyst
GB201615197D0 (en) 2016-09-07 2016-10-19 Mexichem Fluor Sa De Cv Catalyst and process using the catalyst
FR3064275B1 (fr) 2017-03-21 2019-06-07 Arkema France Procede de chauffage et/ou climatisation d'un vehicule
FR3064264B1 (fr) 2017-03-21 2019-04-05 Arkema France Composition a base de tetrafluoropropene
US20200069553A1 (en) * 2018-08-31 2020-03-05 Honeywell International Inc. Personal care spray compositions and methods comprising trans-1-chloro-3,3,3-trifluoropropene
CA3110090A1 (en) * 2018-08-31 2020-03-05 Formulated Solutions, Llc Cryogenic, kinetically active formulations and systems for their dispensing
FR3089127B1 (fr) * 2018-11-30 2020-11-20 Aptar France Sas Dispositif de distribution de produit fluide synchronisé avec l'inhalation
GB2580623A (en) 2019-01-17 2020-07-29 Mexichem Fluor Sa De Cv Method
US20220331212A1 (en) * 2019-08-28 2022-10-20 Honeywell International Inc. NON-FLAMMABLE, DRY PERSONAL CARE PRODUCT CONTAINING trans-1233zd AND ETHANOL
GB2593283B (en) * 2020-01-28 2023-09-13 Chiesi Farm Spa Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation
US20230080276A1 (en) * 2020-02-20 2023-03-16 Chiesi Farmaceutici S.P.A. Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation
CA3226155A1 (en) 2021-07-09 2023-01-12 Astrazeneca Pharmaceuticals Lp Compositions, methods and systems for aerosol drug delivery
WO2023039103A1 (en) * 2021-09-08 2023-03-16 Kindeva Drug Delivery L.P. Metered dose inhalers and suspension compositions
JP2026509779A (ja) * 2022-03-01 2026-03-25 キンデーバ ドラッグ デリバリー リミティド パートナーシップ 定量吸入器及び高用量懸濁液
EP4673113A1 (en) * 2023-03-02 2026-01-07 Kindeva Drug Delivery L.P. Metered dose inhalers and solutions including cannabinoids in hfo-1234ze(e)
WO2025229354A1 (en) 2024-05-03 2025-11-06 Senari Pharma Ltd Aerosol comprising salbutamol sulfate and beclomethasone dipropionate
US20260007598A1 (en) * 2024-07-05 2026-01-08 Honeywell International Inc. Compositions, devices and methods for respritory delivery of active pharmaceutical ingredients
US12496272B1 (en) 2024-07-31 2025-12-16 Amphastar Pharmaceuticals, Inc. Stable epinephrine suspension formulation for inhalation with HFO propellant
US20260076900A1 (en) * 2024-09-16 2026-03-19 Solstice Advanced Materials Us, Inc. Ipratropium delivery compositions, devices and methods
US12383516B1 (en) * 2025-01-06 2025-08-12 Amphastar Pharmaceuticals, Inc. Albuterol aerosol suspension formulation for oral inhalation with high amount of green propellant hydrofluoroolefin (HFO) and free of co-solvent

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB844597A (en) 1959-04-14 1960-08-17 Arthur Abbey Preparation of 3,3,3-trifluoropropene
US2889379A (en) * 1957-02-06 1959-06-02 Dow Chemical Co Preparation of 3, 3, 3-trifluoropropene
US2931840A (en) * 1958-11-25 1960-04-05 Du Pont Process for preparing 2, 3, 3, 3-tetrafluoropropene
US2996555A (en) * 1959-06-25 1961-08-15 Dow Chemical Co Preparation of 2, 3, 3, 3-tetrafluoropropene
US3472826A (en) * 1968-05-23 1969-10-14 Union Carbide Corp Saturated hydrocarbon prepolymer and reaction products thereof
US3659023A (en) * 1970-05-11 1972-04-25 Baxter Laboratories Inc Method of inducing anesthesia with 2-bromo-1 1 2 3 3-pentafluoropropane
US3723318A (en) * 1971-11-26 1973-03-27 Dow Corning Propellants and refrigerants based on trifluoropropene
US3996299A (en) * 1973-02-08 1976-12-07 Phillips Petroleum Company Fluoro compound preparation
US3884826A (en) * 1973-07-20 1975-05-20 Barnes Hind Pharm Inc Thixotropic cleaning agent for hard contact lenses
US4465786A (en) * 1982-09-27 1984-08-14 General Electric Company Catalyst composition for the preparation of 3,3,3-trifluoropropene
US4798818A (en) * 1987-11-27 1989-01-17 Dow Corning Corporation Catalyst composition and process for its preparation
JPH01207250A (ja) * 1988-02-12 1989-08-21 Daikin Ind Ltd 含フツ素オレフインの製造方法
US5766573A (en) * 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
CA2026566A1 (en) 1989-02-02 1990-08-03 Asahi Glass Process for producing a chlorine-containing 2-2-difluoropropane
CA2026568C (en) * 1989-02-02 1999-12-14 Asahi Glass Company Ltd. Process for producing a hydrogen-containing 2,2-difluoropropane
US5162594A (en) * 1990-10-11 1992-11-10 E. I. Du Pont De Nemours And Company Process for production of polyfluoroolefins
US5290539A (en) * 1990-12-21 1994-03-01 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
BE1005096A3 (fr) 1991-07-10 1993-04-20 Solvay Procede pour la preparation de 1-chloro-1,1,3,3,3-pentafluoropropane et de 1,1,1,3,3,3-hexafluoropropane.
JP3026841B2 (ja) * 1991-12-12 2000-03-27 グラクソ、グループ、リミテッド 医 薬
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
KR950701896A (ko) 1992-06-05 1995-05-17 이노우에 노리유키 1,1,1,2,3-펜타플루오로프로펜의 제조방법 및 1,1,1,2,3-펜타플루오로프로판의 제조방법
US5395997A (en) 1993-07-29 1995-03-07 Alliedsignal Inc. Process for the preparation of hydrofluorocarbons having 3 to 7 carbon atoms
US6809226B1 (en) * 1993-08-04 2004-10-26 Solvay (Societe Anonyme) Process for the preparation of 1-chloro-1-fluoroethane and/or 1,1-difluoroethane
US5446217A (en) * 1994-05-16 1995-08-29 Alliedsignal Inc. Processes for the preparation of fluorinated olefins and hydrofluorocarbons using fluorinated olefin
DE770048T1 (de) * 1994-07-11 1998-01-02 Allied Signal Inc Verfahren zur herstellung von 1,1,1,3,3-pentafluorpropan
US6755942B1 (en) * 1995-08-01 2004-06-29 E. I. Du Pont De Nemours And Company Process for the manufacture of halocarbons and selected compounds and azeotropes with HF
US5710382A (en) * 1995-09-26 1998-01-20 The Dow Chemical Company Aluminum nitride, aluminum nitride containing solid solutions and aluminum nitride composites prepared by combustion synthesis and sintered bodies prepared therefrom
WO1997037956A1 (en) * 1996-04-10 1997-10-16 E.I. Du Pont De Nemours And Company Process for the manufacture of halogenated propanes containing end-carbon fluorine
US6111150A (en) * 1996-06-20 2000-08-29 Central Glass Company, Limited Method for producing 1,1,1,3,3,-pentafluoropropane
US5900185A (en) * 1996-09-27 1999-05-04 University Of New Mexico Tropodegradable bromine-containing halocarbon additives to decrease flammability of refrigerants, foam blowing agents, solvents, aerosol propellants, and sterilants
US6300378B1 (en) * 1996-09-27 2001-10-09 University Of New Mexico Tropodegradable bromine-containing halocarbon additives to decrease flammability of refrigerants foam blowing agents solvents aerosol propellants and sterilants
US6023004A (en) * 1996-11-12 2000-02-08 Alliedsignal, Inc. Liquid phase catalytic fluorination of hydrochlorocarbon and hydrochlorofluorocarbon
DE69812901T2 (de) * 1997-01-31 2003-11-06 E.I. Du Pont De Nemours And Co., Wilmington Katalytische herstellung von pentafluorpropenen
US5811604A (en) 1997-02-05 1998-09-22 Alliedsignal, Inc. Continuous production of 1,1,1,3,3,3-hexafluoropropane and 1-chloro-1,1,3,3,3-pentafluoropropane
US5986151A (en) * 1997-02-05 1999-11-16 Alliedsignal Inc. Fluorinated propenes from pentafluoropropane
RU2181114C2 (ru) 1997-03-24 2002-04-10 И.Ай.Дю Пон Де Немурс Энд Кампани Способ получения аддуктов фторсодержащих углеводородов и олефинов
US6120752A (en) 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
US5969198A (en) * 1997-06-27 1999-10-19 Alliedsignal Inc. Process for the preparation of 1,1,1,3,3-pentafluoropropane
US6031141A (en) * 1997-08-25 2000-02-29 E. I. Du Pont De Nemours And Company Fluoroolefin manufacturing process
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
JP3886229B2 (ja) 1997-11-11 2007-02-28 セントラル硝子株式会社 １，３，３，３−テトラフルオロプロペンの製造法
US6270689B1 (en) 1998-03-26 2001-08-07 Ikon Corporation Blend compositions of trifluoroiodomethane, tetrafluoroethane and difluoroethane
ATE253896T1 (de) * 1998-06-18 2003-11-15 Boehringer Ingelheim Pharma Zwei oder mehrere wirkstoffe enthaltende pharmazeutische aerosolformulierungen
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
WO2000000215A1 (en) * 1998-06-29 2000-01-06 Inhale Therapeutic Systems, Inc. Particulate delivery systems and methods of use
KR100796220B1 (ko) 1998-06-29 2008-01-21 넥타르 테라퓨틱스 미립자 전달 시스템 및 사용 방법
US6124510A (en) * 1998-07-21 2000-09-26 Elf Atochem North America, Inc. 1234ze preparation
US6063970A (en) * 1998-10-08 2000-05-16 Laroche Industries, Inc. Process for preparing fluorinated aliphatic compounds
JP2000169404A (ja) 1998-12-11 2000-06-20 Tosoh Corp 含フッ素オレフィン類の臭素化方法
JP2000178543A (ja) 1998-12-14 2000-06-27 Daikin Ind Ltd 共沸乃至共沸様組成物
US6290930B1 (en) 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
GB9828737D0 (en) 1998-12-29 1999-02-17 Star Refrigeration Vaporisable composition
BR0012650A (pt) 1999-07-21 2002-04-09 Halocarbon Prod Corp Produção de fluorocarbonos alifáticos
GB0009609D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic compositions
BR0113190B1 (pt) * 2000-08-11 2010-12-14 conjunto de martelo para rotor de triturador rotativo, triturador rotativo, conjunto para formar parte de um rotor e rotor de triturador.
US6548719B1 (en) 2001-09-25 2003-04-15 Honeywell International Process for producing fluoroolefins
PT2277972T (pt) * 2002-10-25 2019-06-11 Honeywell Int Inc Composições contendo olefinas substituídas por flúor
US7230146B2 (en) 2003-10-27 2007-06-12 Honeywell International Inc. Process for producing fluoropropenes
US7279451B2 (en) * 2002-10-25 2007-10-09 Honeywell International Inc. Compositions containing fluorine substituted olefins
US7592494B2 (en) * 2003-07-25 2009-09-22 Honeywell International Inc. Process for the manufacture of 1,3,3,3-tetrafluoropropene
US7880040B2 (en) * 2004-04-29 2011-02-01 Honeywell International Inc. Method for producing fluorinated organic compounds
US7524805B2 (en) * 2004-04-29 2009-04-28 Honeywell International Inc. Azeotrope-like compositions of tetrafluoropropene and hydrofluorocarbons
FR2865731B1 (fr) * 2004-01-30 2007-09-07 Solvay Procede de fabrication d'un hydrofluoroalcane
US6969701B2 (en) * 2004-04-16 2005-11-29 Honeywell International Inc. Azeotrope-like compositions of tetrafluoropropene and trifluoroiodomethane
US8383867B2 (en) * 2004-04-29 2013-02-26 Honeywell International Inc. Method for producing fluorinated organic compounds
US7951982B2 (en) * 2004-04-29 2011-05-31 Honeywell International Inc. Method for producing fluorinated organic compounds
ES2528181T7 (es) 2004-04-29 2020-03-30 Honeywell Int Inc Procedimientos para la síntesis de 1,3,3,3-tetrafluoropropeno y 2,3,3,3-tetrafluoropropeno
US7674939B2 (en) * 2004-04-29 2010-03-09 Honeywell International Inc. Method for producing fluorinated organic compounds
US7659434B2 (en) * 2004-04-29 2010-02-09 Honeywell International Inc. Method for producing fluorinated organic compounds
CN1972887B (zh) 2004-04-29 2010-10-13 霍尼韦尔国际公司 1,3,3,3-四氟丙烯的合成方法
US6977316B1 (en) * 2004-12-08 2005-12-20 Honeywell International Inc. Direct one-step synthesis of trifluoromethyl iodide
US7196236B2 (en) 2004-12-08 2007-03-27 Honeywell International Inc. Direct one-step synthesis of trifluoromethyl iodide
US7071367B1 (en) * 2004-12-09 2006-07-04 Honeywell International Inc. Direct one-step synthesis of CF3-I
US7026520B1 (en) * 2004-12-09 2006-04-11 Honeywell International Inc. Catalytic conversion of hydrofluoroalkanol to hydrofluoroalkene
US6958424B1 (en) * 2004-12-10 2005-10-25 Honeywell International Inc. Process for fluoroalkenes
US7026521B1 (en) * 2005-03-28 2006-04-11 Honeywell International Inc. Methane and methyl chloride as selective reducing agent in the transformation of hydrochlorofluorocarbons or chlorofluorocarbons to hydrofluorocarbons
US7135601B2 (en) * 2005-03-28 2006-11-14 Honeywell International Inc. Catalytic method for the production of fluoroalkylenes from chlorofluorohydrocarbons
US7132578B1 (en) * 2005-07-14 2006-11-07 Honeywell International Inc. One-step synthesis of CF3-1
WO2007019355A1 (en) 2005-08-05 2007-02-15 E. I. Du Pont De Nemours And Company Process for the preparation of 1,3,3,3-tetrafluoropropene and/or 2,3,3,3-tetrafluoropropene

Also Published As

Publication number Publication date
US20160324778A1 (en) 2016-11-10
US20230157953A1 (en) 2023-05-25
JP2015155414A (ja) 2015-08-27
US20250248938A1 (en) 2025-08-07
JP2013151503A (ja) 2013-08-08
US9308199B2 (en) 2016-04-12
US20190125671A1 (en) 2019-05-02
US20060269484A1 (en) 2006-11-30

Similar Documents

Publication Publication Date Title
PE20240808A1 (es) Composiciones, metodos y sistemas para la administracion de farmacos en aerosol
BR9916865A (pt) Composição farmacêutica em aerossol contendohfa 227 e hfa 134a
BR112022015758A2 (pt) Aerossol compreendendo 5-metóxi-n,n-dimetiltriptamina
CO5031245A1 (es) Inhaladores de dosis regulada a presion y formulaciones farmaceuticas de aerosol
BR112017010551A2 (pt) composto, métodos para ativação de guanilato ciclase solúvel, para tratamento de uma ou mais condições selecionadas a partir de uma doença em um paciente e para tratamento de uma doença ou condição, composição farmacêutica, uso de um composto, e, medicamento.
BRPI0607168A2 (pt) terapia de combinação parenteral, composição farmacêutica, processo para preparar uma composição farmacêutica e método de tratamento
AR101593A2 (es) Formulación superfina de formoterol
AR038641A1 (es) Formulacion superfina de formoterol
BR0009975A (pt) Inalador de pó para um medicamento combinado
AR080444A1 (es) Metodos para la utilizacion de cotransportadores de sodio-glucosa 1 y 2
MX2016004316A (es) Inhalador de polvo seco.
BR112018011266A2 (pt) ?composição farmacêutica, recipiente vedado, inalador dosimetrado, e, métodos para tratar um paciente que sofre ou é propenso a sofrer de um distúrbio respiratório e para estabilizar uma composição farmacêutica?
BRPI0412059A (pt) método para a preparação de formulação de liberação controlada
CY1114215T1 (el) Φαρμακευτικες συνθεσεις διαλυματος για υπο πιεση εισπνευστηρες μετρουμενης δοσης
AR022886A1 (es) Utilizacion de xenon o mezclas de gas xenon composicion para el tratamiento de intoxicaciones neurologicas y procedimiento para la preparacion de un medicamento inhalable
ES2570401T3 (es) Métodos de tratamiento usando dosis únicas de oritavancina
BR112015026053A2 (pt) composição farmacêutica, recipiente vedado, inalador dosimetrado, e, métodos para tratamento de um paciente sofrendo ou susceptível a sofrer de um distúrbio respiratório e para fabricação de uma composição farmacêutica
BRPI0508170A (pt) formulações farmacêuticas para inaladores de pó seco, que compreendem um ingrediente ativo de potência de baixa dosagem
BR0208012A (pt) Usos de pelo menos duas drogas e um propelente hfa e de pelo menos uma composição farmaceêutica, e, inalador acondicionado para tratar asma
BRPI0509026A (pt) formulação de aerossol, método para a prevenção e tratamento de infecção causada por bactéria do trato respiratório, e, solução
BR112013011594A2 (pt) sistemas de combinação de lâminas e líquidos para a liberação de medicamento dérmico
MX2021006751A (es) Inhalador de polvo seco con propionato de fluticasona y xinafoato de salmeterol.
BR112021018994A2 (pt) Formulação de combinação tripla de baixa dose
BRPI0608791B8 (pt) cápsulas para inaladores, uso de uma composição de polímero e processo para a secagem de pós para inalação
WO2022228652A1 (en) Means and method for treating viral infections

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements