BRPI0604761A - detecção de metilação de gene - Google Patents
detecção de metilação de geneInfo
- Publication number
- BRPI0604761A BRPI0604761A BRPI0604761-0A BRPI0604761A BRPI0604761A BR PI0604761 A BRPI0604761 A BR PI0604761A BR PI0604761 A BRPI0604761 A BR PI0604761A BR PI0604761 A BRPI0604761 A BR PI0604761A
- Authority
- BR
- Brazil
- Prior art keywords
- gene methylation
- methylation detection
- gene
- detection
- various
- Prior art date
Links
- 230000011987 methylation Effects 0.000 title abstract 3
- 238000007069 methylation reaction Methods 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
DETECçãO DE METILAçãO DE GENE. Métodos, kits e composições, para detecção do estado de metilação de vários genes, são úteis em várias aplicações diagnósticas envolvendo distúrbios proliferativos suspeitos, tais como câncer de próstata.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71779005P | 2005-09-15 | 2005-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0604761A true BRPI0604761A (pt) | 2007-08-28 |
Family
ID=37682657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0604761-0A BRPI0604761A (pt) | 2005-09-15 | 2006-09-15 | detecção de metilação de gene |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20070059753A1 (pt) |
| EP (1) | EP1764419B1 (pt) |
| JP (1) | JP2007075114A (pt) |
| CN (1) | CN1966724A (pt) |
| AR (1) | AR055437A1 (pt) |
| AT (1) | ATE555214T1 (pt) |
| AU (1) | AU2006213972A1 (pt) |
| BR (1) | BRPI0604761A (pt) |
| CA (1) | CA2561991A1 (pt) |
| DK (1) | DK1764419T3 (pt) |
| ES (1) | ES2386729T3 (pt) |
| IL (1) | IL178118A0 (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP312998A0 (en) * | 1998-04-23 | 1998-05-14 | Commonwealth Scientific And Industrial Research Organisation | Diagnostic assay |
| US7906288B2 (en) * | 2006-01-04 | 2011-03-15 | The Johns Hopkins University | Compare-MS: method rapid, sensitive and accurate detection of DNA methylation |
| CN101153336B (zh) | 2006-09-27 | 2011-09-07 | 香港中文大学 | 检测dna甲基化程度的方法和试剂盒 |
| CA2699856C (en) * | 2007-09-17 | 2019-08-20 | Oncomethylome Sciences Sa | Improved methylation detection |
| JP2011509688A (ja) * | 2008-01-22 | 2011-03-31 | ベリデックス・エルエルシー | 前立腺癌におけるgstp1高メチル化の発見 |
| JP2011530287A (ja) * | 2008-08-05 | 2011-12-22 | ベリデックス・エルエルシー | 前立腺癌メチル化分析 |
| ES2686309T3 (es) * | 2011-02-02 | 2018-10-17 | Exact Sciences Development Company, Llc | Análisis digital de secuencia de la metilación de ADN |
| GB201322034D0 (en) | 2013-12-12 | 2014-01-29 | Almac Diagnostics Ltd | Prostate cancer classification |
| EP2942400A1 (en) | 2014-05-09 | 2015-11-11 | Lifecodexx AG | Multiplex detection of DNA that originates from a specific cell-type |
| US10801067B2 (en) | 2014-05-09 | 2020-10-13 | Eurofins Lifecodexx Gmbh | Detection of DNA that originates from a specific cell-type and related methods |
| EP3168309B8 (en) | 2015-11-10 | 2020-06-03 | Eurofins LifeCodexx GmbH | Detection of foetal chromosomal aneuploidies using dna regions that are differentially methylated between the foetus and the pregnant female |
| KR20250117473A (ko) | 2017-11-30 | 2025-08-04 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 유방암 검출방법 |
| CN113215260A (zh) * | 2021-06-18 | 2021-08-06 | 杭州昱鼎生物科技有限公司 | 一种gstp1,apc和rassf1在制备前列腺癌标志物中的应用及其试剂盒 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5536648A (en) * | 1988-12-09 | 1996-07-16 | Amrad Corporation Limited | Amplified DNA assay using a double stranded DNA binding protein |
| GB9609441D0 (en) | 1996-05-04 | 1996-07-10 | Zeneca Ltd | Process |
| US6017704A (en) * | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| AUPP312998A0 (en) * | 1998-04-23 | 1998-05-14 | Commonwealth Scientific And Industrial Research Organisation | Diagnostic assay |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| US6686155B2 (en) * | 2001-06-14 | 2004-02-03 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression |
| AU2002352745A1 (en) * | 2001-11-16 | 2003-06-10 | The Johns Hopkins University School Of Medicine | Method of detection of prostate cancer |
| US20040146868A1 (en) | 2003-01-24 | 2004-07-29 | Epigenomics Ag | Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the development of peripheral zone prostate cancer |
| AU2003900368A0 (en) * | 2003-01-24 | 2003-02-13 | Human Genetic Signatures Pty Ltd | Assay for nucleic acid molecules |
| WO2004087957A2 (en) * | 2003-04-03 | 2004-10-14 | Oncomethylome Sciences S.A. | Hypermethylated genes and cervical cancer |
| EP1636381B1 (en) * | 2003-06-23 | 2011-01-05 | Epigenomics AG | Methods and nucleic acids for the analysis of colon cell proliferative disorders |
| EP1649050A2 (en) * | 2003-06-24 | 2006-04-26 | Epigenomics AG | Improved heavymethyl assay for the methylation analysis of the gstpi gene |
| US8062849B2 (en) * | 2003-10-28 | 2011-11-22 | The Johns Hopkins University | Quantitative multiplex methylation-specific PCR |
-
2006
- 2006-09-13 US US11/520,233 patent/US20070059753A1/en not_active Abandoned
- 2006-09-14 ES ES06254777T patent/ES2386729T3/es active Active
- 2006-09-14 IL IL178118A patent/IL178118A0/en unknown
- 2006-09-14 JP JP2006249663A patent/JP2007075114A/ja active Pending
- 2006-09-14 AU AU2006213972A patent/AU2006213972A1/en not_active Abandoned
- 2006-09-14 AT AT06254777T patent/ATE555214T1/de active
- 2006-09-14 DK DK06254777.3T patent/DK1764419T3/da active
- 2006-09-14 EP EP06254777A patent/EP1764419B1/en not_active Not-in-force
- 2006-09-15 CA CA002561991A patent/CA2561991A1/en not_active Abandoned
- 2006-09-15 AR ARP060104052A patent/AR055437A1/es not_active Application Discontinuation
- 2006-09-15 CN CNA2006101431787A patent/CN1966724A/zh active Pending
- 2006-09-15 BR BRPI0604761-0A patent/BRPI0604761A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1764419A2 (en) | 2007-03-21 |
| AU2006213972A1 (en) | 2007-03-29 |
| CN1966724A (zh) | 2007-05-23 |
| EP1764419B1 (en) | 2012-04-25 |
| US20070059753A1 (en) | 2007-03-15 |
| JP2007075114A (ja) | 2007-03-29 |
| IL178118A0 (en) | 2006-12-31 |
| DK1764419T3 (da) | 2012-08-06 |
| ATE555214T1 (de) | 2012-05-15 |
| EP1764419A3 (en) | 2007-06-13 |
| AR055437A1 (es) | 2007-08-22 |
| CA2561991A1 (en) | 2007-03-15 |
| ES2386729T3 (es) | 2012-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |