BRPI0606132A2 - formas cristalinas de docetaxel e processos para seu preparo - Google Patents

formas cristalinas de docetaxel e processos para seu preparo

Info

Publication number
BRPI0606132A2
BRPI0606132A2 BRPI0606132-0A BRPI0606132A BRPI0606132A2 BR PI0606132 A2 BRPI0606132 A2 BR PI0606132A2 BR PI0606132 A BRPI0606132 A BR PI0606132A BR PI0606132 A2 BRPI0606132 A2 BR PI0606132A2
Authority
BR
Brazil
Prior art keywords
processes
preparation
crystalline forms
docetaxel
docetaxel crystalline
Prior art date
Application number
BRPI0606132-0A
Other languages
English (en)
Inventor
Alessandro Pontiroli
Marco Villa
Judith Aronhime
Sigalit Levi
Original Assignee
Sicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Inc filed Critical Sicor Inc
Publication of BRPI0606132A2 publication Critical patent/BRPI0606132A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

FORMAS CRISTALINAS DE DOCETAXEL E PROCESSOS PARA SEU PREPARO. São fornecidas novas formas de docetaxel cristalino, bem como composições farmacêuticas e métodos de tratamento. São fornecidos também novos processos para fabricação de docetaxel cristalino.
BRPI0606132-0A 2005-10-12 2006-10-12 formas cristalinas de docetaxel e processos para seu preparo BRPI0606132A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72532105P 2005-10-12 2005-10-12
US72664705P 2005-10-17 2005-10-17
US73687005P 2005-11-16 2005-11-16
PCT/US2006/040308 WO2007044950A2 (en) 2005-10-12 2006-10-12 Crystalline forms of docetaxel and processes for their preparation

Publications (1)

Publication Number Publication Date
BRPI0606132A2 true BRPI0606132A2 (pt) 2009-06-02

Family

ID=37907299

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606132-0A BRPI0606132A2 (pt) 2005-10-12 2006-10-12 formas cristalinas de docetaxel e processos para seu preparo

Country Status (8)

Country Link
US (1) US20070142457A1 (pt)
EP (1) EP1819688A2 (pt)
JP (1) JP2008523111A (pt)
KR (1) KR20070088784A (pt)
BR (1) BRPI0606132A2 (pt)
CA (1) CA2620308A1 (pt)
TW (1) TW200730518A (pt)
WO (1) WO2007044950A2 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101291658B (zh) 2005-08-31 2014-04-16 阿布拉科斯生物科学有限公司 用于制备稳定性增加的水难溶性药物的组合物和方法
US7771751B2 (en) 2005-08-31 2010-08-10 Abraxis Bioscience, Llc Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
KR100995390B1 (ko) * 2006-01-02 2010-11-19 주식회사 삼양제넥스 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법
KR20080100264A (ko) 2006-03-21 2008-11-14 닥터 레디스 레보러터리즈 리미티드 도세탁셀의 다형체와 그 제조방법
EP2330101A1 (en) * 2006-10-20 2011-06-08 Scinopharm Singapore Pte, Ltd. Process for making crystalline docetaxel
KR100878455B1 (ko) * 2007-04-10 2009-01-13 한미약품 주식회사 안정한 무수결정형 도세탁셀 및 이의 제조방법
WO2009006590A2 (en) * 2007-07-04 2009-01-08 Dr. Reddy's Laboratories Ltd. Docetaxel process and polymorphs
CN101337951B (zh) * 2007-07-06 2011-09-14 江苏恒瑞医药股份有限公司 一种多烯紫杉醇无水结晶物的制备方法
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
KR101068230B1 (ko) * 2009-03-03 2011-09-28 정규능 도세탁셀의 제조방법, 그 중간체 및 이의 제조방법
JP5824511B2 (ja) 2010-05-03 2015-11-25 テイコク ファーマ ユーエスエー インコーポレーテッド 非水タキサンプロエマルジョン配合物ならびにそれを調製および使用する方法
KR20120096200A (ko) * 2011-02-22 2012-08-30 동아제약주식회사 결정형 도세탁셀 및 이의 제조방법
CN103764637A (zh) * 2011-04-12 2014-04-30 普拉斯化学品有限公司 卡巴他赛的固态形式及其制备方法
TWI526437B (zh) * 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
US8633240B2 (en) 2012-06-01 2014-01-21 The University Of Utah Research Foundation Paclitaxel trihydrates and methods of making thereof
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN107683134B (zh) 2015-05-15 2021-02-23 珠海贝海生物技术有限公司 多西他赛及人血清白蛋白复合物
CN115487312B (zh) 2016-10-27 2025-02-07 珠海贝海生物技术有限公司 多西他赛和人血清白蛋白的中性pH组合物
CN108822062B (zh) * 2018-09-07 2020-08-28 无锡紫杉药业有限公司 一种多西他赛的精制方法
JP7734677B2 (ja) 2020-02-04 2025-09-05 珠海貝海生物技術有限公司 ドセタキセル製剤
AU2022443487B2 (en) 2022-02-25 2026-05-21 Zhuhai Beihai Biotech Co., Ltd. Taxotere composition and method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703049B1 (fr) * 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.
FR2722191B1 (fr) * 1994-07-08 1996-08-23 Rhone Poulenc Rorer Sa Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
US5681846A (en) * 1995-03-17 1997-10-28 Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel
DE19518082A1 (de) * 1995-05-17 1996-11-21 Merck Patent Gmbh 4(-Arylaminomethylen)-2,4-dihydropyrazol-3-one
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
CU22723A1 (es) * 1997-04-02 2002-02-28 Dalmer Lab Sa Mezcla de ácidos grasos primarios de alto peso molecular obtenidos de la cera de cana de azúcar y sus usos farmacéuticos
WO2003047508A2 (en) * 2001-11-30 2003-06-12 Bristol-Myers Squibb Company Paclitaxel solvates
US6838569B2 (en) * 2002-12-16 2005-01-04 Dabur India Limited Process for preparation of paclitaxel trihydrate and docetaxel trihydrate
CN1805968A (zh) * 2003-06-18 2006-07-19 明治制果株式会社 结晶卡巴培南中间体

Also Published As

Publication number Publication date
EP1819688A2 (en) 2007-08-22
WO2007044950A2 (en) 2007-04-19
KR20070088784A (ko) 2007-08-29
US20070142457A1 (en) 2007-06-21
JP2008523111A (ja) 2008-07-03
WO2007044950A3 (en) 2007-06-14
CA2620308A1 (en) 2007-04-19
TW200730518A (en) 2007-08-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A E 5A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012.