BRPI0606750A2 - composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica - Google Patents

composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica

Info

Publication number
BRPI0606750A2
BRPI0606750A2 BRPI0606750-6A BRPI0606750A BRPI0606750A2 BR PI0606750 A2 BRPI0606750 A2 BR PI0606750A2 BR PI0606750 A BRPI0606750 A BR PI0606750A BR PI0606750 A2 BRPI0606750 A2 BR PI0606750A2
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutically acceptable
pharmaceutical composition
acceptable salt
receptor
Prior art date
Application number
BRPI0606750-6A
Other languages
English (en)
Inventor
Pier Andrea Borea
Delia Preti
Mojgan Aghzadeh Tabrizi
Pier Baraldi
Original Assignee
King Pharmaceuticals Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by King Pharmaceuticals Res & Dev filed Critical King Pharmaceuticals Res & Dev
Publication of BRPI0606750A2 publication Critical patent/BRPI0606750A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPOSTO OU UM SAL FARMACEUTICAMENTE ACEITáVEL DO MESMO, E, COMPOSIçãO FARMACêUTICA. A invenção refere-se a uma classe de novos antagonistas para o receptor de adenosina A2 32. Estes compostos são úteis como agentes terapêuticos para várias doenças e condições médicas que são mediadas pelo receptor de A2 32. Os compostos da presente invenção são também úteis como agentes diagnósticos para o receptor de A2 32.
BRPI0606750-6A 2005-02-02 2006-02-01 composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica BRPI0606750A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64972605P 2005-02-02 2005-02-02
US11/344,295 US7435740B2 (en) 2005-02-02 2006-01-31 Adenosine A3 receptor modulators
PCT/US2006/003477 WO2006083916A2 (en) 2005-02-02 2006-02-01 Novel adenosine a3 receptor modulators

Publications (1)

Publication Number Publication Date
BRPI0606750A2 true BRPI0606750A2 (pt) 2009-07-14

Family

ID=36777854

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606750-6A BRPI0606750A2 (pt) 2005-02-02 2006-02-01 composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica

Country Status (11)

Country Link
US (1) US7435740B2 (pt)
EP (1) EP1845993A4 (pt)
JP (1) JP2008538099A (pt)
KR (1) KR20070100331A (pt)
AU (1) AU2006210817B2 (pt)
BR (1) BRPI0606750A2 (pt)
CA (1) CA2596612A1 (pt)
IL (1) IL184532A0 (pt)
MX (1) MX2007008501A (pt)
NZ (1) NZ556649A (pt)
WO (1) WO2006083916A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088403A1 (en) * 2007-05-07 2009-04-02 Randy Blakely A3 adenosine receptors as targets for the modulation of central serotonergic signaling
US8765775B2 (en) 2008-01-24 2014-07-01 Universitaet Zuerich Anti-angiogenic compounds
US20110190324A1 (en) * 2008-07-16 2011-08-04 Edward Leung Methods of treating atherosclerosis
US9199102B2 (en) 2009-07-21 2015-12-01 Oradin Pharmaceutical Ltd. A3 adenosine receptor ligands for modulation of pigmentation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586429B2 (en) * 2000-11-29 2003-07-01 Cell Therapeutics, Inc. Tricyclic fused xanthine compounds and their uses

Also Published As

Publication number Publication date
JP2008538099A (ja) 2008-10-09
AU2006210817A2 (en) 2006-08-10
US7435740B2 (en) 2008-10-14
CA2596612A1 (en) 2006-08-10
AU2006210817B2 (en) 2010-12-23
EP1845993A2 (en) 2007-10-24
KR20070100331A (ko) 2007-10-10
EP1845993A4 (en) 2009-03-11
WO2006083916A2 (en) 2006-08-10
WO2006083916A3 (en) 2007-12-21
US20060178385A1 (en) 2006-08-10
MX2007008501A (es) 2007-09-14
NZ556649A (en) 2010-03-26
AU2006210817A1 (en) 2006-08-10
IL184532A0 (en) 2007-10-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014.