BRPI0607239A2 - usos de uma quantidade terapeuticamente ou profilaticamente eficaz de 4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol-1,3-d iona, de (3r)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, e de (3s)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, ou um sal ou solvato farmaceuticamente aceitável das mesmas, composição farmacêutica, e, forma de dosagem unitária simples - Google Patents

usos de uma quantidade terapeuticamente ou profilaticamente eficaz de 4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol-1,3-d iona, de (3r)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, e de (3s)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, ou um sal ou solvato farmaceuticamente aceitável das mesmas, composição farmacêutica, e, forma de dosagem unitária simples

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Publication number
BRPI0607239A2
BRPI0607239A2 BRPI0607239-9A BRPI0607239A BRPI0607239A2 BR PI0607239 A2 BRPI0607239 A2 BR PI0607239A2 BR PI0607239 A BRPI0607239 A BR PI0607239A BR PI0607239 A2 BRPI0607239 A2 BR PI0607239A2
Authority
BR
Brazil
Prior art keywords
isoindol
amino
methyl
dioxopiperidin
dione
Prior art date
Application number
BRPI0607239-9A
Other languages
English (en)
Inventor
George W Muller
Roger S Chen
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of BRPI0607239A2 publication Critical patent/BRPI0607239A2/pt

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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Abstract

USOS DE UMA QUANTIDADE TERAPEUTICAMENTE OU PROFILATICAMENTE EFICAZ DE 4-AMINO-2-(3-MIETIL-2,6- DIOXOPIPERIDIN-3-IL)-ISOINDOL- 1 ,3-DIONA, DE (3R)-4-AMINO-2- (3-METIL-2,6-DIOXOPIPERIDIIN-3-IL)-ISOINDOL- 1 ,3-DIONA, E DE (3 S)-4-AMINO-2-(3 -METIL-2,6-DIOXOPIPERIDIN-3 -IL)-ISOINDOL- 1,3- DIONA, OU UM SAL OU SOL VATO FARMACEUTICAMENTE ACEITáVEL DAS MESMAS, COMPOSIçãO FARMACêUTICA, E, FORMA DE DOSAGEM UNITáRIA SIMPLES. Esta invenção refere-se a 4-amino-2-(3-metil-2,6- dioxopiperidin-3 -il)-i soindol- 1,3 -diona racêmica e estereomericamente pura, e pró-drogas, sais e solvatos da mesma. Revela-se a síntese, métodos de uso, e composições farmacêuticas de 4-amino-2-(3 -metil-2 ,6-dioxo-piperidin-3 -il)-isoindol- 1 ,3-diona racêmica e estereomericamente pura, e pró-drogas, sais e solvatos da mesma.
BRPI0607239-9A 2005-01-25 2006-01-24 usos de uma quantidade terapeuticamente ou profilaticamente eficaz de 4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol-1,3-d iona, de (3r)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, e de (3s)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, ou um sal ou solvato farmaceuticamente aceitável das mesmas, composição farmacêutica, e, forma de dosagem unitária simples BRPI0607239A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64650505P 2005-01-25 2005-01-25
PCT/US2006/002503 WO2006081251A2 (en) 2005-01-25 2006-01-24 Methods and compositions using 4-amino-2-(3-methyl-2,6-dioxopiperidin-3-yl)-isoindole-1-3-dione

Publications (1)

Publication Number Publication Date
BRPI0607239A2 true BRPI0607239A2 (pt) 2009-08-25

Family

ID=36609267

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607239-9A BRPI0607239A2 (pt) 2005-01-25 2006-01-24 usos de uma quantidade terapeuticamente ou profilaticamente eficaz de 4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol-1,3-d iona, de (3r)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, e de (3s)-4-amino-2-(3-metil-2,6-dioxopiperidin-3-il)-isoindol- 1,3-diona, ou um sal ou solvato farmaceuticamente aceitável das mesmas, composição farmacêutica, e, forma de dosagem unitária simples

Country Status (13)

Country Link
US (1) US20060205787A1 (pt)
EP (1) EP1848433A2 (pt)
JP (1) JP2008528514A (pt)
KR (1) KR20070099031A (pt)
CN (1) CN101141960A (pt)
AR (1) AR052196A1 (pt)
AU (1) AU2006208201A1 (pt)
BR (1) BRPI0607239A2 (pt)
CA (1) CA2595711A1 (pt)
IL (1) IL184821A0 (pt)
MX (1) MX2007008903A (pt)
WO (1) WO2006081251A2 (pt)
ZA (1) ZA200707010B (pt)

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