BRPI0607294A2 - processes for synthesis of aryl pyrrolidones as well as mixing - Google Patents

processes for synthesis of aryl pyrrolidones as well as mixing

Info

Publication number
BRPI0607294A2
BRPI0607294A2 BRPI0607294-1A BRPI0607294A BRPI0607294A2 BR PI0607294 A2 BRPI0607294 A2 BR PI0607294A2 BR PI0607294 A BRPI0607294 A BR PI0607294A BR PI0607294 A2 BRPI0607294 A2 BR PI0607294A2
Authority
BR
Brazil
Prior art keywords
synthesis
processes
well
mixing
aryl
Prior art date
Application number
BRPI0607294-1A
Other languages
Portuguese (pt)
Inventor
Yun He
David H Woodmanse
Ha-Soon Choi
Zhicheng Wang
Baogen Wu
Truc Ngoc Nguyen
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of BRPI0607294A2 publication Critical patent/BRPI0607294A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCESSOS PARA SìNTESE DE ARIL PIRROLIDONAS, BEM COMO MISTURA. A presente invenção refere-se a métodos para a síntese assimétrica de aril pirrolidonas com alto rendimento e grande excesso enantiomérico.PROCESSES FOR SYNTHESIS OF ARYL PYROLIDONES AS WELL AS A MIX. The present invention relates to methods for the asymmetric synthesis of high yield aryl pyrrolidones with large enantiomeric excess.

BRPI0607294-1A 2005-01-28 2006-01-30 processes for synthesis of aryl pyrrolidones as well as mixing BRPI0607294A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64803905P 2005-01-28 2005-01-28
PCT/US2006/003240 WO2006081562A2 (en) 2005-01-28 2006-01-30 Synthesis of aryl pyrrolidones

Publications (1)

Publication Number Publication Date
BRPI0607294A2 true BRPI0607294A2 (en) 2009-08-25

Family

ID=36741151

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607294-1A BRPI0607294A2 (en) 2005-01-28 2006-01-30 processes for synthesis of aryl pyrrolidones as well as mixing

Country Status (10)

Country Link
EP (1) EP1841424A4 (en)
JP (1) JP2008528625A (en)
KR (1) KR100890696B1 (en)
CN (1) CN101111246A (en)
AU (1) AU2006209241B2 (en)
BR (1) BRPI0607294A2 (en)
CA (1) CA2593816A1 (en)
MX (1) MX2007008974A (en)
RU (1) RU2007132260A (en)
WO (1) WO2006081562A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013526542A (en) 2010-05-12 2013-06-24 アッヴィ・インコーポレイテッド Indazole inhibitor of kinase
CN101979378B (en) * 2010-10-13 2012-06-27 中国科学院上海有机化学研究所 Method for synthesizing chiral gamma-lactam compounds
RU2485100C1 (en) * 2012-02-07 2013-06-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" 1-aryl-4-benzoyl-3-hydroxy-5-methoxycarbonyl-2,5-dihydro-1h-pyrrol-2-ones exhibiting analgesic activity and method for preparing them
AU2014357342B2 (en) 2013-12-03 2019-01-17 Fmc Corporation Pyrrolidinones as herbicides
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
UA125012C2 (en) 2014-07-02 2021-12-29 ЕфЕмСі КОРПОРЕЙШН PIPERIDINONE HERBICIDES
BR112017009701B1 (en) 2014-12-08 2021-09-08 Fmc Corporation COMPOUND AND COMPOUND PREPARATION METHODS
WO2016164201A1 (en) 2015-04-10 2016-10-13 E I Du Pont De Nemours And Company Substituted cyclic amides as herbicides
BR112017020094B1 (en) 2015-04-27 2022-01-11 Fmc Corporation COMPOUND, HERBICIDAL COMPOSITIONS, HERBICIDE MIXTURE AND METHOD FOR CONTROLLING UNWANTED VEGETATION GROWTH
RU2750293C2 (en) 2015-05-12 2021-06-25 ЭфЭмСи Корпорейшн Aryl-substituted bicyclic compounds as herbicides
CN107690426B (en) 2015-05-29 2021-07-06 Fmc公司 Substituted cyclic amides as herbicides
RU2017142979A (en) 2015-06-02 2019-07-15 ЭфЭмСи Корпорейшн SUBSTITUTED CYCLIC AMIDES AND THEIR APPLICATION AS HERBICIDES
RU2720994C2 (en) 2015-07-31 2020-05-15 Е.И.Дюпон Де Немур Энд Компани Novel cyclic n-carboxamide compounds used as herbicides
ES2958741T3 (en) 2016-12-21 2024-02-14 Fmc Corp Nitrone herbicides
UA126576C2 (en) 2017-03-21 2022-11-02 ЕфЕмСі КОРПОРЕЙШН HERBICIDE MIXTURE, COMPOSITION AND METHOD
CN110691516B (en) 2017-03-21 2022-10-28 Fmc公司 Pyrrolidone and preparation method thereof
AR111967A1 (en) 2017-05-30 2019-09-04 Fmc Corp AMIDES HERBICIDES
AR111839A1 (en) 2017-05-30 2019-08-21 Fmc Corp LACTAMAS 3-REPLACED HERBICIDES
CN116782894A (en) * 2020-10-06 2023-09-19 D.E.肖研究有限责任公司 Lactam compounds as Kv1.3 potassium Shaker channel blockers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058986A (en) * 1962-10-16 N-ammoalkyl-x-phenyl-x-lower alkyl-z-
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
US3956914A (en) * 1974-11-14 1976-05-18 The Marison Company Spin lathe
JP2002363160A (en) * 2001-06-05 2002-12-18 Sumitomo Chem Co Ltd Method for producing optically active 4-aryl-2-piperidinones
AU2003285952A1 (en) * 2002-10-21 2004-05-13 Irm Llc Pyrrolidones with anti-hiv activity
JP4351859B2 (en) * 2003-04-14 2009-10-28 三菱レイヨン株式会社 Process for producing optically active β-aryl compounds
KR100896889B1 (en) * 2005-01-28 2009-05-14 아이알엠 엘엘씨 Phenyl-substituted pyrrolidones

Also Published As

Publication number Publication date
KR100890696B1 (en) 2009-03-26
AU2006209241B2 (en) 2009-10-22
RU2007132260A (en) 2009-03-10
AU2006209241A1 (en) 2006-08-03
EP1841424A2 (en) 2007-10-10
MX2007008974A (en) 2007-09-18
CN101111246A (en) 2008-01-23
JP2008528625A (en) 2008-07-31
WO2006081562A3 (en) 2006-10-19
KR20070097555A (en) 2007-10-04
CA2593816A1 (en) 2006-08-03
WO2006081562A2 (en) 2006-08-03
EP1841424A4 (en) 2010-01-27

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012.