BRPI0607475A2 - promotor de regeneração de célula pancreática, e promotor de produção de insulina em célula pancreática - Google Patents

promotor de regeneração de célula pancreática, e promotor de produção de insulina em célula pancreática

Info

Publication number
BRPI0607475A2
BRPI0607475A2 BRPI0607475-8A BRPI0607475A BRPI0607475A2 BR PI0607475 A2 BRPI0607475 A2 BR PI0607475A2 BR PI0607475 A BRPI0607475 A BR PI0607475A BR PI0607475 A2 BRPI0607475 A2 BR PI0607475A2
Authority
BR
Brazil
Prior art keywords
pancreatic cell
promoter
insulin production
pancreatic
regeneration
Prior art date
Application number
BRPI0607475-8A
Other languages
English (en)
Inventor
Kenji Kangawa
Takashi Akamizu
Taiga Irako
Shuichi Koda
Naomi Wakabayashi
Original Assignee
Asubio Pharma Co Ltd
Univ Kyoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36927405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0607475(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asubio Pharma Co Ltd, Univ Kyoto filed Critical Asubio Pharma Co Ltd
Publication of BRPI0607475A2 publication Critical patent/BRPI0607475A2/pt
Publication of BRPI0607475B1 publication Critical patent/BRPI0607475B1/pt
Publication of BRPI0607475B8 publication Critical patent/BRPI0607475B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROMOTOR DE REGENERAçãO DE CéLULA <225> PANCREáTICA, E PROMOTOR DE PRODUçãO DE INSULINA EM CéLULA <225> PANCREáTICA. A presente invenção refere-se a um fármaco para promover neogênese ou regeneração de células <225> pancreáticas que produzem e secretam insulina e para promover a produção de insulina em células <225>, compreendendo grelina ou um derivado desta como um componente efetivo.
BRPI0607475A 2005-02-23 2006-02-23 promotor de regeneração de célula ß pancreática, e promotor de produção de insulina em célula ß pancreática BRPI0607475B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005046562 2005-02-23
JP2005-046562 2005-02-23
JP2006-003219 2006-01-11
JP2006003219 2006-01-11
PCT/JP2006/303243 WO2006090767A1 (ja) 2005-02-23 2006-02-23 膵臓β細胞の再生促進剤及び膵臓β細胞におけるインスリン産生促進剤

Publications (3)

Publication Number Publication Date
BRPI0607475A2 true BRPI0607475A2 (pt) 2009-09-08
BRPI0607475B1 BRPI0607475B1 (pt) 2020-02-11
BRPI0607475B8 BRPI0607475B8 (pt) 2021-05-25

Family

ID=36927405

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607475A BRPI0607475B8 (pt) 2005-02-23 2006-02-23 promotor de regeneração de célula ß pancreática, e promotor de produção de insulina em célula ß pancreática

Country Status (11)

Country Link
US (1) US7803768B2 (pt)
EP (1) EP1862173B1 (pt)
JP (1) JP4843827B2 (pt)
KR (1) KR101295104B1 (pt)
CN (1) CN101128213B (pt)
AU (1) AU2006216218B2 (pt)
BR (1) BRPI0607475B8 (pt)
CA (1) CA2598864C (pt)
IL (1) IL184931A (pt)
RU (1) RU2403058C2 (pt)
WO (1) WO2006090767A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100056507A (ko) * 2007-09-11 2010-05-27 몬도바이오테크 래보래토리즈 아게 치료제로서의 펩티드 ｐｒｏ－ｇｌｙ－ｔｈｒ－ｃｙｓ－ｇｌｕ－ｉｌｅ－ｃｙｓ－ａｌａ－ｔｙｒ－ａｌａ－ａｌａ－ｃｙｓ－ｔｈｒ－ｇｌｙ－ｃｙｓ의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2401939T3 (es) 1999-07-23 2013-04-25 Kenji Kangawa Nuevos péptidos
WO2001056592A1 (en) 2000-02-01 2001-08-09 Novo Nordisk A/S Use of compounds for the regulation of food intake
JP4493913B2 (ja) 2001-01-31 2010-06-30 中外製薬株式会社 低栄養症状疾患治療剤
AU2002351593A1 (en) * 2001-12-18 2003-06-30 Theratechnologies Inc. Pharmaceutical compositions comprising unacylated ghrelin and therapeutical uses thereof
WO2004004772A1 (ja) * 2002-07-05 2004-01-15 Chugai Seiyaku Kabushiki Kaisha 糖尿病治療剤
US7825090B2 (en) * 2003-10-24 2010-11-02 Alizé Pharma SAS Use of ghrelin and unacylated ghrelin compositions for treating insulin resistance
US20090149512A1 (en) * 2004-05-14 2009-06-11 Novo Nordisk A/S Use of Ghrelin Antagonists to the Treatment of Certain CNS Diseases

Also Published As

Publication number Publication date
EP1862173B1 (en) 2014-12-17
CA2598864A1 (en) 2006-08-31
CN101128213B (zh) 2013-05-08
RU2403058C2 (ru) 2010-11-10
JP4843827B2 (ja) 2011-12-21
EP1862173A4 (en) 2012-03-28
KR20070110856A (ko) 2007-11-20
US7803768B2 (en) 2010-09-28
JPWO2006090767A1 (ja) 2008-07-24
CA2598864C (en) 2016-02-16
US20090143284A1 (en) 2009-06-04
BRPI0607475B8 (pt) 2021-05-25
AU2006216218A1 (en) 2006-08-31
EP1862173A1 (en) 2007-12-05
WO2006090767A1 (ja) 2006-08-31
IL184931A0 (en) 2007-12-03
CN101128213A (zh) 2008-02-20
BRPI0607475B1 (pt) 2020-02-11
IL184931A (en) 2011-08-31
RU2007135225A (ru) 2009-03-27
KR101295104B1 (ko) 2013-08-09
AU2006216218B2 (en) 2011-08-11

Similar Documents

Publication Publication Date Title
ECSP078060A (es) 2,4-diamino-pirimidinas como inhibidores de aurora
ECSP11011079A (es) Nuevos compuestos de hidroxiareno.
ATE536192T1 (de) Vernetzte hyaluronsäure und kollagen und ihre verwendungen
BRPI0920914A8 (pt) Perácidos alfa-ceto e métodos para produzir e usar os mesmos.
ECSP11010831A (es) Compuestos orgánicos para la cicatrización de heridas
CL2009000782A1 (es) Metodo que comprende un compuesto derivado de oximetilen-arilo sustituido, inhibidores de dpp-iv; y su uso en el tratamiento de la diabetes y disminucion de trigliceridos, entre otras enfermedades.
CL2009000393A1 (es) Composición farmaceutica que comprende a) un agente farmaceutico activable, b) un agente activo plasmonico; util para el tratamiento de trastornos de proliferación celular.
UA107812C2 (xx) ДВОЗАМІЩЕНІ ОКТАГІДРОПІРОЛО$3,4-с]ПІРОЛИ ЯК МОДУЛЯТОРИ ОРЕКСИНОВИХ РЕЦЕПТОРІВ
UY32009A (es) 5-alquinil-pirimidinas
CR20110257A (es) Aminotetrahidropiranos como inhibidores de dipeptidil peptidasa-iv para el tratamiento o prevención de diabetes
BRPI0908421B8 (pt) solução estável de um composto farmacêutico
UY33199A (es) 5-alquinil-pirimidinas.
CL2007002682A1 (es) Compuestos derivados de 4-metilpiridopirimidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar el crecimiento anormal de celulas, como cancer.
HN2011001446A (es) Compuesto utiles para inhibir chk1
CO6362015A2 (es) Derivados de acido 1-amino-2ciclobutiletilboronico
WO2009149956A3 (en) Fusion protein and use thereof
UY29149A1 (es) Tiazolil-dihidro-indazoles
ECSP11010816A (es) Nuevos Compuestos
BRPI0912164A2 (pt) processo para a degradação de lignina.
PY0710494A (es) Dimeros de derivados de artemisinina, su preparación y su aplicación en terapéutica.
BR112015002295A2 (pt) métodos e composições para indução in vivo de formação de célula beta pancreática
MX2012001409A (es) Fragmento de agrina modificado capaz de restaurar la potencia muscular para utilizarse como un medicamento.
BR112012015449A2 (pt) suspensão de monoidrato de calcipotriol, monoidrato de calcipotriol, processo para preparar nanocristais de monoidrato de calcipotriol, e, composição farmacêutica
BR112012019920A2 (pt) derivados de piridazina úteis como agonístas de canabinoide-2.
BR112013018738A2 (pt) novos derivados de tetrahidroquinolina

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: KYOTO UNIVERSITY (JP) , DAIICHI SANKYO COMPANY, LI

Free format text: TRANSFERIDO POR INCORPORACAO DE: ASUBIO PHAMA CO., LTD.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/02/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/02/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B25A Requested transfer of rights approved

Owner name: DAIICHI SANKYO COMPANY, LIMITED (JP)