BRPI0607873A2 - oxazolidinona de oxindol como agente antibacteriano - Google Patents

oxazolidinona de oxindol como agente antibacteriano

Info

Publication number
BRPI0607873A2
BRPI0607873A2 BRPI0607873-7A BRPI0607873A BRPI0607873A2 BR PI0607873 A2 BRPI0607873 A2 BR PI0607873A2 BR PI0607873 A BRPI0607873 A BR PI0607873A BR PI0607873 A2 BRPI0607873 A2 BR PI0607873A2
Authority
BR
Brazil
Prior art keywords
oxazolidinone
antibacterial agent
oxindole
compound
antibacterial
Prior art date
Application number
BRPI0607873-7A
Other languages
English (en)
Inventor
Mikail Fedor Gordeev
Prasad Venkata Nagendra Josyula Vara
Gary Wayne Luehr
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0607873A2 publication Critical patent/BRPI0607873A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

OXAZOLIDINONA DE OXINDOL COMO AGENTE ANTIBACTERIANO. A presente invenção refere-se a um composto de fórmula I ou um sal farmacêuticamente aceitável do mesmo em que R~ 1~ é C~ 1-4~alquila, opcionalmente substituida com um átomo de flúor, ou R~ 1~ é uma ciclopropila ou ciclopropilmetila; e R^ 2^ é metila ou etila. O composto é útil como agentes antibacterianos.
BRPI0607873-7A 2005-04-06 2006-03-27 oxazolidinona de oxindol como agente antibacteriano BRPI0607873A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66871605P 2005-04-06 2005-04-06
US68400005P 2005-05-24 2005-05-24
PCT/IB2006/000952 WO2006106426A1 (en) 2005-04-06 2006-03-27 An oxindole oxazolidinone as antibacterial agent

Publications (1)

Publication Number Publication Date
BRPI0607873A2 true BRPI0607873A2 (pt) 2009-10-20

Family

ID=36648715

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607873-7A BRPI0607873A2 (pt) 2005-04-06 2006-03-27 oxazolidinona de oxindol como agente antibacteriano

Country Status (21)

Country Link
US (1) US20060229348A1 (pt)
EP (1) EP1869029A1 (pt)
KR (1) KR20070116989A (pt)
AP (1) AP2007004173A0 (pt)
AR (1) AR053350A1 (pt)
AU (1) AU2006231918A1 (pt)
BR (1) BRPI0607873A2 (pt)
CA (1) CA2603943A1 (pt)
CR (1) CR9418A (pt)
DO (1) DOP2006000079A (pt)
EA (1) EA200701895A1 (pt)
GT (1) GT200600132A (pt)
IL (1) IL186051A0 (pt)
MX (1) MX2007011873A (pt)
NL (1) NL1031524C2 (pt)
NO (1) NO20075547L (pt)
PE (1) PE20061356A1 (pt)
TN (1) TNSN07374A1 (pt)
TW (1) TW200637855A (pt)
UY (1) UY29453A1 (pt)
WO (1) WO2006106426A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102214988B1 (ko) * 2019-06-20 2021-02-10 영남대학교 산학협력단 신규한 옥시인돌 유도체 및 이를 유효성분으로 함유하는 항균용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2865211B2 (ja) * 1988-09-15 1999-03-08 ファルマシア・アンド・アップジョン・カンパニー ５’―インドリニル―５β―アミドメチルオキサゾリジン―２―オン類、３―（縮合環置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類および３―（窒素原子置換）フェニル―５β―アミドメチルオキサゾリジン―２―オン類
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
DE19649095A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue Heteroaryl-Oxazolidinone
DE69912264T2 (de) * 1998-04-14 2004-07-22 Samsung Fine Chemicals Co., Ltd. Verfahren zur herstellung chiraler (s)-2,3-disubstituierter 1-propylamin-derivate
JP2003501351A (ja) * 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
PE20011124A1 (es) * 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
EP1781642A1 (en) * 2004-08-06 2007-05-09 Pharmacia & Upjohn Company LLC Oxazolidinones containing oxindoles as antibacterial agents

Also Published As

Publication number Publication date
GT200600132A (es) 2006-11-22
CR9418A (es) 2007-10-21
DOP2006000079A (es) 2006-11-15
KR20070116989A (ko) 2007-12-11
EP1869029A1 (en) 2007-12-26
MX2007011873A (es) 2007-11-07
AP2007004173A0 (en) 2007-10-31
TNSN07374A1 (fr) 2009-03-17
PE20061356A1 (es) 2007-01-13
NO20075547L (no) 2007-11-01
EA200701895A1 (ru) 2008-04-28
US20060229348A1 (en) 2006-10-12
WO2006106426A1 (en) 2006-10-12
IL186051A0 (en) 2008-02-09
NL1031524A1 (nl) 2006-10-09
NL1031524C2 (nl) 2007-01-30
TW200637855A (en) 2006-11-01
AU2006231918A1 (en) 2006-10-12
UY29453A1 (es) 2006-11-30
AR053350A1 (es) 2007-05-02
CA2603943A1 (en) 2006-10-12

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]