CR9417A - 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales - Google Patents

7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales

Info

Publication number
CR9417A
CR9417A CR9417A CR9417A CR9417A CR 9417 A CR9417 A CR 9417A CR 9417 A CR9417 A CR 9417A CR 9417 A CR9417 A CR 9417A CR 9417 A CR9417 A CR 9417A
Authority
CR
Costa Rica
Prior art keywords
antibacterial agents
fluoro
dihidro
oxazolidinones
ona
Prior art date
Application number
CR9417A
Other languages
English (en)
Inventor
Wayne Luehr Gary
Fedor Grodeev Mikhail
Prasad Venkata Nagendra Vara
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of CR9417A publication Critical patent/CR9417A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion proporciona un compuesto de formula I o una sal farmaceuticamente aceptable del mismo en la que R1 es alquilo C1-4, opcionalmente sustituido con un atomo de fluoro, o R 1 es un ciclopropilo o ciclopropilmetilo; y R2 es metilo o etilo. estos compuestos son Utiles como agentes antibacterianos.
CR9417A 2005-04-06 2007-10-05 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales CR9417A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66871505P 2005-04-06 2005-04-06
US68403305P 2005-05-24 2005-05-24

Publications (1)

Publication Number Publication Date
CR9417A true CR9417A (es) 2007-12-04

Family

ID=36636389

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9417A CR9417A (es) 2005-04-06 2007-10-05 7-fluoro-1,3-dihidro-indol-2-ona oxazolidinonas como agentes antibacteriales

Country Status (21)

Country Link
US (1) US7435751B2 (es)
EP (1) EP1869030A1 (es)
JP (1) JP2008534672A (es)
KR (1) KR20070108938A (es)
AP (1) AP2007004172A0 (es)
AR (1) AR053839A1 (es)
AU (1) AU2006231919A1 (es)
BR (1) BRPI0610533A2 (es)
CA (1) CA2603899A1 (es)
CR (1) CR9417A (es)
DO (1) DOP2006000080A (es)
GT (1) GT200600133A (es)
IL (1) IL186119A0 (es)
MX (1) MX2007012386A (es)
NL (1) NL1031525C2 (es)
NO (1) NO20075505L (es)
PE (1) PE20061301A1 (es)
TN (1) TNSN07373A1 (es)
TW (1) TW200716101A (es)
UY (1) UY29452A1 (es)
WO (1) WO2006106427A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080262056A1 (en) * 2004-08-06 2008-10-23 Pfizer Inc Oxindole Oxazolidinones as Antibacterial Agents
KR100891485B1 (ko) 2007-10-29 2009-04-02 주식회사 만도 디스크 브레이크의 주차브레이크 장치
US20090124737A1 (en) * 2007-11-12 2009-05-14 Eastman Chemical Company Acrylic plastisol viscosity reducers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2157934T3 (es) 1988-09-15 2001-09-01 Upjohn Co Fenil-5-beta-amidometiloxazolidin-2-onas sustituidas con nitrogeno en la posicion 3.
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
DE4425613A1 (de) 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de) 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
US6015429A (en) * 1994-09-08 2000-01-18 Gore Enterprise Holdings, Inc. Procedures for introducing stents and stent-grafts
DE19649095A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue Heteroaryl-Oxazolidinone
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
CA2318969A1 (en) 1998-01-23 1999-07-29 Mikhail F. Gordeev Oxazolidinone combinatorial libraries, compositions and methods of preparation
DE69912264T2 (de) 1998-04-14 2004-07-22 Samsung Fine Chemicals Co., Ltd. Verfahren zur herstellung chiraler (s)-2,3-disubstituierter 1-propylamin-derivate
AU1379900A (en) 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel substituted phenyloxazolidone derivatives
WO2000032599A1 (en) 1998-11-27 2000-06-08 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
EP1181288B1 (en) 1999-05-27 2003-07-30 PHARMACIA & UPJOHN COMPANY Bicyclic oxazolidinones as antibacterial agent
ATE321024T1 (de) 2000-10-17 2006-04-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonverbindungen
DE60212959T2 (de) 2001-04-07 2007-02-15 Astrazeneca Ab Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika
ATE374463T1 (de) 2001-04-20 2007-10-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonen
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
US20080262056A1 (en) * 2004-08-06 2008-10-23 Pfizer Inc Oxindole Oxazolidinones as Antibacterial Agents

Also Published As

Publication number Publication date
CA2603899A1 (en) 2006-10-12
MX2007012386A (es) 2007-11-07
US7435751B2 (en) 2008-10-14
WO2006106427A8 (en) 2007-12-06
NL1031525C2 (nl) 2007-01-30
KR20070108938A (ko) 2007-11-13
GT200600133A (es) 2006-11-29
WO2006106427A1 (en) 2006-10-12
TNSN07373A1 (fr) 2009-03-17
AR053839A1 (es) 2007-05-23
IL186119A0 (en) 2008-01-20
PE20061301A1 (es) 2007-02-09
NO20075505L (no) 2007-10-31
JP2008534672A (ja) 2008-08-28
BRPI0610533A2 (pt) 2010-06-29
NL1031525A1 (nl) 2006-10-09
US20060229349A1 (en) 2006-10-12
DOP2006000080A (es) 2006-12-15
AU2006231919A1 (en) 2006-10-12
TW200716101A (en) 2007-05-01
AP2007004172A0 (en) 2007-10-31
UY29452A1 (es) 2006-11-30
EP1869030A1 (en) 2007-12-26

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