BRPI0608334A2 - uso de uma formulação de clobetasol em lìquido pulverizado para o tratamento de psorìase - Google Patents
uso de uma formulação de clobetasol em lìquido pulverizado para o tratamento de psorìaseInfo
- Publication number
- BRPI0608334A2 BRPI0608334A2 BRPI0608334-0A BRPI0608334A BRPI0608334A2 BR PI0608334 A2 BRPI0608334 A2 BR PI0608334A2 BR PI0608334 A BRPI0608334 A BR PI0608334A BR PI0608334 A2 BRPI0608334 A2 BR PI0608334A2
- Authority
- BR
- Brazil
- Prior art keywords
- psoriasis
- treatment
- clobetasol
- powdered
- formulation
- Prior art date
Links
- 201000004681 Psoriasis Diseases 0.000 title abstract 4
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 title abstract 3
- 229960002842 clobetasol Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 229960004703 clobetasol propionate Drugs 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
- 239000003945 anionic surfactant Substances 0.000 abstract 1
- FCSHDIVRCWTZOX-DVTGEIKXSA-N clobetasol Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O FCSHDIVRCWTZOX-DVTGEIKXSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
USO DE UMA FORMULAçãO DE CLOBETASOL EM LìQUIDO PULVERIZADO PARA O TRATAMENTO DE PSORIASE. A presente invenção provê um uso de uma composição farmacêutica contendo uma quantidade efetiva de propionato de clobetasol, uma composição farmacêutica preferida contendo propionato de clobetasol, álcool etílico, miristato de isopropila e agente tensoativo aniónico para a preparação de um medicamento, pulverizado sobre a pele afligida com psoriase diariamente por pelo menos quatro semanas, para o tratamento de psoriase.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67494605P | 2005-04-25 | 2005-04-25 | |
| PCT/US2006/014903 WO2006115987A2 (en) | 2005-04-25 | 2006-04-20 | Use of a clobetasol spray formulation to treat psoriasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0608334A2 true BRPI0608334A2 (pt) | 2009-12-01 |
Family
ID=37215257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0608334-0A BRPI0608334A2 (pt) | 2005-04-25 | 2006-04-20 | uso de uma formulação de clobetasol em lìquido pulverizado para o tratamento de psorìase |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20060239929A1 (pt) |
| EP (1) | EP1885373B1 (pt) |
| JP (1) | JP2008539236A (pt) |
| KR (2) | KR20080047312A (pt) |
| CN (1) | CN101208096A (pt) |
| AU (1) | AU2006241285B2 (pt) |
| BR (1) | BRPI0608334A2 (pt) |
| CA (1) | CA2607434A1 (pt) |
| DK (1) | DK1885373T3 (pt) |
| ES (1) | ES2539634T3 (pt) |
| HU (1) | HUE025462T2 (pt) |
| MX (1) | MX2007013230A (pt) |
| PL (1) | PL1885373T3 (pt) |
| PT (1) | PT1885373E (pt) |
| RU (1) | RU2397769C2 (pt) |
| SI (1) | SI1885373T1 (pt) |
| WO (1) | WO2006115987A2 (pt) |
| ZA (1) | ZA200709327B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010129707A1 (en) * | 2009-05-05 | 2010-11-11 | Amgen Inc. | Etanercept in combination with glucocorticoids for use in treating psoriasis |
| JP5833007B2 (ja) | 2009-08-31 | 2015-12-16 | ドクター・レディーズ・ラボラトリーズ・リミテッド | ステロイドを含む局所製剤 |
| US10080760B2 (en) * | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
| US9789123B2 (en) | 2010-10-21 | 2017-10-17 | Cadila Healthcare Limited | Topical pharmaceutical compositions containing nanodroplets for the treatment of psoriasis |
| US8992994B2 (en) | 2010-10-21 | 2015-03-31 | Cadila Healthcare Limited | Topical pharmaceutical compositions containing nanodroplets for the treatment psoriasis |
| US8809307B2 (en) | 2010-11-22 | 2014-08-19 | Dow Pharmaceutical Sciences, Inc. | Pharmaceutical formulations containing corticosteroids for topical administration |
| US20160184431A1 (en) * | 2014-03-11 | 2016-06-30 | Promius Pharma Llc | Topical compositions comprising a corticosteroid |
| ES2857602T3 (es) | 2014-03-11 | 2021-09-29 | Promius Pharma Llc | Composiciones tópicas de corticosteroides |
| WO2017037663A1 (en) | 2015-09-02 | 2017-03-09 | Cadila Healthcare Limited | Topical compositions comprising corticosteroids |
| KR102399484B1 (ko) | 2015-09-15 | 2022-05-17 | 주식회사 엘지생활건강 | 건선 치료제 전달을 위한 용해성 미세바늘 패치 |
| KR102631435B1 (ko) | 2016-06-10 | 2024-01-29 | 주식회사 엘지생활건강 | 타박상 치료제 전달을 위한 용해성 미세바늘 패치 |
| US20210069214A1 (en) * | 2019-09-06 | 2021-03-11 | Encore Dermatology, Inc. | Topical compositions comprising a corticosteroid for the treatment of psoriasis in pediatric patients |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5972920A (en) * | 1998-02-12 | 1999-10-26 | Dermalogix Partners, Inc. | Formulation containing a carrier, active ingredient, and surfactant for treating skin disorders |
| US5990100A (en) * | 1998-03-24 | 1999-11-23 | Panda Pharmaceuticals, L.L.C. | Composition and method for treatment of psoriasis |
| US5886038A (en) * | 1998-03-24 | 1999-03-23 | Panda Pharmaceuticals, L.L.C. | Composition and method for treatment of psoriasis |
| FR2761600B1 (fr) * | 1998-06-19 | 2000-03-31 | Oreal | Composition moussante pour le lavage et le traitement des cheveux et/ou du cuir chevelu a base d'un principe actif, d'un tensioactif anionique, d'un tensioactif amphotere et d'un agent propenetrant |
| US6579512B2 (en) * | 2001-06-15 | 2003-06-17 | Crutchfield, Iii Charles E. | Topical steroid spray |
-
2006
- 2006-04-20 AU AU2006241285A patent/AU2006241285B2/en active Active
- 2006-04-20 KR KR1020077026561A patent/KR20080047312A/ko not_active Ceased
- 2006-04-20 CN CNA2006800229419A patent/CN101208096A/zh active Pending
- 2006-04-20 WO PCT/US2006/014903 patent/WO2006115987A2/en not_active Ceased
- 2006-04-20 US US11/408,105 patent/US20060239929A1/en not_active Abandoned
- 2006-04-20 SI SI200631954T patent/SI1885373T1/sl unknown
- 2006-04-20 PL PL06750845T patent/PL1885373T3/pl unknown
- 2006-04-20 BR BRPI0608334-0A patent/BRPI0608334A2/pt not_active Application Discontinuation
- 2006-04-20 HU HUE06750845A patent/HUE025462T2/en unknown
- 2006-04-20 RU RU2007143420/14A patent/RU2397769C2/ru active
- 2006-04-20 JP JP2008508939A patent/JP2008539236A/ja active Pending
- 2006-04-20 KR KR1020117022050A patent/KR20110108426A/ko not_active Ceased
- 2006-04-20 ES ES06750845.7T patent/ES2539634T3/es active Active
- 2006-04-20 DK DK06750845.7T patent/DK1885373T3/en active
- 2006-04-20 EP EP20060750845 patent/EP1885373B1/en active Active
- 2006-04-20 CA CA002607434A patent/CA2607434A1/en not_active Abandoned
- 2006-04-20 PT PT67508457T patent/PT1885373E/pt unknown
- 2006-04-20 MX MX2007013230A patent/MX2007013230A/es unknown
-
2007
- 2007-10-30 ZA ZA200709327A patent/ZA200709327B/xx unknown
-
2014
- 2014-01-17 US US14/157,579 patent/US20140148426A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2607434A1 (en) | 2006-11-02 |
| JP2008539236A (ja) | 2008-11-13 |
| KR20080047312A (ko) | 2008-05-28 |
| EP1885373A4 (en) | 2010-08-18 |
| WO2006115987A3 (en) | 2006-12-14 |
| WO2006115987A8 (en) | 2008-10-16 |
| RU2007143420A (ru) | 2009-06-10 |
| SI1885373T1 (sl) | 2016-03-31 |
| HUE025462T2 (en) | 2016-02-29 |
| PL1885373T3 (pl) | 2015-12-31 |
| EP1885373A2 (en) | 2008-02-13 |
| MX2007013230A (es) | 2008-04-17 |
| ZA200709327B (en) | 2009-01-28 |
| EP1885373B1 (en) | 2015-05-20 |
| ES2539634T3 (es) | 2015-07-02 |
| KR20110108426A (ko) | 2011-10-05 |
| AU2006241285B2 (en) | 2011-04-14 |
| AU2006241285A1 (en) | 2006-11-02 |
| RU2397769C2 (ru) | 2010-08-27 |
| US20060239929A1 (en) | 2006-10-26 |
| DK1885373T3 (en) | 2015-08-10 |
| PT1885373E (pt) | 2015-09-10 |
| US20140148426A1 (en) | 2014-05-29 |
| CN101208096A (zh) | 2008-06-25 |
| WO2006115987A2 (en) | 2006-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |