BRPI0609769B8 - dispositivo de detecção, sistema de detecção, e, método - Google Patents

dispositivo de detecção, sistema de detecção, e, método

Info

Publication number
BRPI0609769B8
BRPI0609769B8 BRPI0609769A BRPI0609769A BRPI0609769B8 BR PI0609769 B8 BRPI0609769 B8 BR PI0609769B8 BR PI0609769 A BRPI0609769 A BR PI0609769A BR PI0609769 A BRPI0609769 A BR PI0609769A BR PI0609769 B8 BRPI0609769 B8 BR PI0609769B8
Authority
BR
Brazil
Prior art keywords
species
optical modules
detection
fluorescent light
detection device
Prior art date
Application number
BRPI0609769A
Other languages
English (en)
Inventor
W Robole Barry
D Ludowise Peter
Bedingham William
Original Assignee
3M Innovative Properties Co
Diasorin S P A
Quest Diagnostics Infectius Disease Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co, Diasorin S P A, Quest Diagnostics Infectius Disease Inc filed Critical 3M Innovative Properties Co
Publication of BRPI0609769A2 publication Critical patent/BRPI0609769A2/pt
Publication of BRPI0609769B1 publication Critical patent/BRPI0609769B1/pt
Publication of BRPI0609769B8 publication Critical patent/BRPI0609769B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/024—Modular construction

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

dispositivo de detecção, sistema de detecção, e, método. são descritas técnicas para a detecção de múltiplas espécies- alvo em pcr em tempo real (reação em cadeia da polimerase). por exemplo, um sistema é descrito, que inclui um dispositivo de aquisição de dado e um dispositivo de detecção acoplado com o dispositivo de aquisição de dado. um dispositivo de detecção inclui um disco rotativo tendo uma pluralidade de câmaras de processo tendo uma pluralidade de espécies que emitem luz fluorescente em diferentes comprimentos de onda. o dispositivo também inclui uma pluralidade de módulos ópticos. cada um dos módulos ópticos é opticamente configurado para excitar as espécies e capturar luz fluorescente emitida pelas espécies em diferentes comprimentos de onda. um feixe de fibras ópticas acoplado com a pluralidade de módulos ópticos transmite a luz fluorescente dos múltiplos módulos ópticos para um único detector.
BRPI0609769A 2005-04-01 2006-03-24 dispositivo de detecção, sistema de detecção, e, método BRPI0609769B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66746105P 2005-04-01 2005-04-01
US60/667461 2005-04-01
US11/174,755 US7709249B2 (en) 2005-04-01 2005-07-05 Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US11/174755 2005-07-05
PCT/US2006/010978 WO2006107627A1 (en) 2005-04-01 2006-03-24 Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector

Publications (3)

Publication Number Publication Date
BRPI0609769A2 BRPI0609769A2 (pt) 2011-10-18
BRPI0609769B1 BRPI0609769B1 (pt) 2018-02-06
BRPI0609769B8 true BRPI0609769B8 (pt) 2019-02-12

Family

ID=36579427

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0609769A BRPI0609769B8 (pt) 2005-04-01 2006-03-24 dispositivo de detecção, sistema de detecção, e, método

Country Status (11)

Country Link
US (1) US7709249B2 (pt)
EP (1) EP1866631B1 (pt)
JP (1) JP5021615B2 (pt)
KR (2) KR20130050391A (pt)
AT (1) ATE507473T1 (pt)
AU (1) AU2006232930A1 (pt)
BR (1) BRPI0609769B8 (pt)
CA (1) CA2602252A1 (pt)
DE (1) DE602006021554D1 (pt)
MX (1) MX2007012158A (pt)
WO (1) WO2006107627A1 (pt)

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US7709249B2 (en) 2010-05-04
ATE507473T1 (de) 2011-05-15
EP1866631A1 (en) 2007-12-19
JP5021615B2 (ja) 2012-09-12
BRPI0609769A2 (pt) 2011-10-18
AU2006232930A1 (en) 2006-10-12
WO2006107627A1 (en) 2006-10-12
US20060223172A1 (en) 2006-10-05
MX2007012158A (es) 2007-12-10
DE602006021554D1 (de) 2011-06-09
CA2602252A1 (en) 2006-10-12
EP1866631B1 (en) 2011-04-27
JP2008534966A (ja) 2008-08-28
KR20130050391A (ko) 2013-05-15
BRPI0609769B1 (pt) 2018-02-06
KR20070122525A (ko) 2007-12-31

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