BRPI0610092A2 - methods for detecting an analyte and nucleic acid in a sample, and for synthesizing a nucleic acid or nucleic acid molecule, reagent kit, uses thereof, a compound, and a method, Nucleic acid or nucleic acid analogue, metallisation product, associated product and compound - Google Patents

methods for detecting an analyte and nucleic acid in a sample, and for synthesizing a nucleic acid or nucleic acid molecule, reagent kit, uses thereof, a compound, and a method, Nucleic acid or nucleic acid analogue, metallisation product, associated product and compound

Info

Publication number
BRPI0610092A2
BRPI0610092A2 BRPI0610092-9A BRPI0610092A BRPI0610092A2 BR PI0610092 A2 BRPI0610092 A2 BR PI0610092A2 BR PI0610092 A BRPI0610092 A BR PI0610092A BR PI0610092 A2 BRPI0610092 A2 BR PI0610092A2
Authority
BR
Brazil
Prior art keywords
nucleic acid
compound
product
methods
synthesizing
Prior art date
Application number
BRPI0610092-9A
Other languages
Portuguese (pt)
Inventor
Thomas Carell
Anja Schwoegler
Glenn Ashley Burley
Johannes Gierlich
Mohammad Reza Mofid
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of BRPI0610092A2 publication Critical patent/BRPI0610092A2/en
Publication of BRPI0610092B1 publication Critical patent/BRPI0610092B1/en
Publication of BRPI0610092B8 publication Critical patent/BRPI0610092B8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

MÉTODOS PARA A DETECÇçO DE UM ANALITO E DE UM ÁCIDO NUCLEICO EM UMA AMOSTRA, E PARA SINTETIZAÇçO DE UMA MOLÉCULA DE ÁCIDO NUCLEICO OU DE ANÁLOGO DE ÁCIDO NUCLEICO, KIT REAGENTE, USOS DO MESMO, DE UM COMPOSTO, E DE UM MÉTODO, MOLÉCULA DE ÁCIDO NUCLEICO OU DE ANÁLOGO DE ÁCIDO NUCLEICO, PRODUTO DE METALIZAÇçO, PRODUTO ASSOCIADO, E, COMPOSTO. A invenção refere-se a métodos e reagentes para a detecção de analitos, e.g., ácidos nucleicos. Os novos métodos e reagentes permitem uma detecção simples e sensível mesmo em amostras biológicas complexas.METHODS FOR THE DETECTION OF ANALYTIC AND NUCLEIC ACID IN A SAMPLE, AND FOR SYNTHESIZING A NUCLEIC ACID OR ANALOGUE MOLECULE, REAGENT KIT, USES OF THE SAME, A COMPOUND, AND A MOLD NUCLEIC ACID OR NUCLEIC ACID ANALOG, METALIZING PRODUCT, ASSOCIATED PRODUCT, AND COMPOUND. The invention relates to methods and reagents for detecting analytes, e.g., nucleic acids. New methods and reagents allow simple and sensitive detection even in complex biological samples.

BRPI0610092A 2005-05-02 2006-04-28 methods for detecting an analyte and nucleic acid in a sample, and synthesizing a nucleic acid or nucleic acid analogue molecule, reagent kit, use thereof, nucleic acid or nucleic acid analogue molecule, and associated product BRPI0610092B8 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US67678505P 2005-05-02 2005-05-02
EP05009618.9 2005-05-02
EP05009618 2005-05-02
US60/676,785 2005-05-02
US75010005P 2005-12-14 2005-12-14
US60/750,100 2005-12-14
EP05027370 2005-12-14
EP05027370.5 2005-12-14
PCT/EP2006/004017 WO2006117161A2 (en) 2005-05-02 2006-04-28 New labelling strategies for the sensitive detection of analytes

Publications (3)

Publication Number Publication Date
BRPI0610092A2 true BRPI0610092A2 (en) 2008-12-09
BRPI0610092B1 BRPI0610092B1 (en) 2018-03-27
BRPI0610092B8 BRPI0610092B8 (en) 2021-07-27

Family

ID=42676666

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0610092A BRPI0610092B8 (en) 2005-05-02 2006-04-28 methods for detecting an analyte and nucleic acid in a sample, and synthesizing a nucleic acid or nucleic acid analogue molecule, reagent kit, use thereof, nucleic acid or nucleic acid analogue molecule, and associated product

Country Status (16)

Country Link
US (1) US8129315B2 (en)
EP (4) EP2270228B1 (en)
JP (1) JP4944098B2 (en)
AR (1) AR053251A1 (en)
AT (1) ATE479699T1 (en)
AU (1) AU2006243370B2 (en)
BR (1) BRPI0610092B8 (en)
CA (1) CA2607530C (en)
DE (1) DE602006016589D1 (en)
DK (1) DK1877415T3 (en)
MX (1) MX2007013296A (en)
PL (1) PL1877415T3 (en)
PT (1) PT1877415E (en)
SI (1) SI1877415T1 (en)
TW (1) TWI406952B (en)
WO (1) WO2006117161A2 (en)

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EP2270228B1 (en) 2005-05-02 2013-08-21 baseclick GmbH New labelling strategies for the sensitive detection of analytes
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US8618297B2 (en) 2008-07-25 2013-12-31 Basf Se Azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions
AU2009298802A1 (en) * 2008-09-23 2010-04-08 Alnylam Pharmaceuticals, Inc. Chemical modifications of monomers and oligonucleotides with cycloaddition
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EP2435461B1 (en) 2009-05-29 2017-08-09 Life Technologies Corporation Scaffolded nucleic acid polymer particles and methods of making and using
US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
US9480752B2 (en) 2012-07-10 2016-11-01 Baseclick Gmbh Anandamide-modified nucleic acid molecules
US9797011B2 (en) 2013-09-13 2017-10-24 Life Technologies Corporation Device preparation using condensed nucleic acid particles
EP3344782A1 (en) * 2015-08-31 2018-07-11 Life Technologies Corporation Colorimetric labeling and detection methods and compositions
CA3117476A1 (en) * 2018-10-05 2020-04-09 Board Of Regents, The University Of Texas System Solid-phase n-terminal peptide capture and release
EP4237573A1 (en) 2020-10-29 2023-09-06 DNA Script Enzymatic synthesis of polynucleotide probes
CN120530202A (en) 2023-01-26 2025-08-22 Dna斯克瑞普特公司 Enzymatic synthesis of polynucleotide probes

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Also Published As

Publication number Publication date
SI1877415T1 (en) 2011-01-31
TWI406952B (en) 2013-09-01
DE602006016589D1 (en) 2010-10-14
ATE479699T1 (en) 2010-09-15
US20090215635A1 (en) 2009-08-27
EP2256126A1 (en) 2010-12-01
WO2006117161A2 (en) 2006-11-09
CA2607530C (en) 2014-07-08
US8129315B2 (en) 2012-03-06
PT1877415E (en) 2010-12-09
AU2006243370A1 (en) 2006-11-09
DK1877415T3 (en) 2010-12-20
AR053251A1 (en) 2007-04-25
EP2270228B1 (en) 2013-08-21
TW200720441A (en) 2007-06-01
EP2266996A3 (en) 2011-06-15
JP4944098B2 (en) 2012-05-30
BRPI0610092B1 (en) 2018-03-27
EP2256126B1 (en) 2015-07-01
EP2266996A2 (en) 2010-12-29
JP2008539703A (en) 2008-11-20
EP2270228A1 (en) 2011-01-05
PL1877415T3 (en) 2011-02-28
WO2006117161A3 (en) 2007-01-11
AU2006243370B2 (en) 2012-06-28
CA2607530A1 (en) 2006-11-09
EP1877415B1 (en) 2010-09-01
EP1877415A2 (en) 2008-01-16
MX2007013296A (en) 2007-12-13
BRPI0610092B8 (en) 2021-07-27

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/04/2006, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO