BRPI0612456A2 - composiÇÕes e mÉtodos para o tratamento da malÁria com cupredoxina e citocromo - Google Patents
composiÇÕes e mÉtodos para o tratamento da malÁria com cupredoxina e citocromoInfo
- Publication number
- BRPI0612456A2 BRPI0612456A2 BRPI0612456-9A BRPI0612456A BRPI0612456A2 BR PI0612456 A2 BRPI0612456 A2 BR PI0612456A2 BR PI0612456 A BRPI0612456 A BR PI0612456A BR PI0612456 A2 BRPI0612456 A2 BR PI0612456A2
- Authority
- BR
- Brazil
- Prior art keywords
- cytochrome
- malaria
- cupredoxin
- compositions
- methods
- Prior art date
Links
- 201000004792 malaria Diseases 0.000 title abstract 6
- 108010052832 Cytochromes Proteins 0.000 title abstract 3
- 102000018832 Cytochromes Human genes 0.000 title abstract 3
- 108010092351 cupredoxin Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 3
- 102100030497 Cytochrome c Human genes 0.000 abstract 2
- 108010075031 Cytochromes c Proteins 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000009182 Parasitemia Diseases 0.000 abstract 2
- 208000030852 Parasitic disease Diseases 0.000 abstract 2
- 210000003743 erythrocyte Anatomy 0.000 abstract 2
- 241000238631 Hexapoda Species 0.000 abstract 1
- 241000223960 Plasmodium falciparum Species 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/80—Cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
COMPOSIÇÕES E MÉTODOS PARA O TRATAMENTO DA MALÁRIA COM CUPREDOXINA E CITOCROMO. Mais particularmente a invenção se refere à cupredoxina e ao citocromo, bem como a seu uso separado ou em conjunto para inibir a disseminação da parasitemia das hemácias de mamíferos e em outros tecidos infectados pelo parasita da malária e, em especial, a parasitemia das hemácias humanas pelo P. falciparum. A invenção provê peptídeos isolados que são variantes, derivados ou equivalentes estruturais das cupredoxinas ou do citocromo c, e composições que compreendem as cupredoxinas e/ou o citocrorno c, ou suas variantes, derivados ou equivalentes estruturais, que forem úteis para o tratamento ou prevenção da infecção por malária em mamíferos. Além disso, a invenção provê métodos para o tratamento de pacientes mamíferos de maneira a prevenir ou inibir o crescimento da infecção da malária em mamíferos. A invenção também provê métodos para evitar o crescimento da infecção da malária em vetores insetos.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68281305P | 2005-05-20 | 2005-05-20 | |
| US11/244,105 US7691383B2 (en) | 2004-10-07 | 2005-10-06 | Cupredoxin derived transport agents and methods of use thereof |
| US78086806P | 2006-03-10 | 2006-03-10 | |
| PCT/US2006/019492 WO2006127477A2 (en) | 2005-05-20 | 2006-05-19 | Compositions and methods for treating malaria with cupredoxin and cytochrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0612456A2 true BRPI0612456A2 (pt) | 2009-02-17 |
Family
ID=37452644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0612456-9A BRPI0612456A2 (pt) | 2005-05-20 | 2006-05-19 | composiÇÕes e mÉtodos para o tratamento da malÁria com cupredoxina e citocromo |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1882039A4 (pt) |
| JP (1) | JP2009504567A (pt) |
| KR (1) | KR20080019615A (pt) |
| AU (2) | AU2006251742A1 (pt) |
| BR (1) | BRPI0612456A2 (pt) |
| CA (1) | CA2607739A1 (pt) |
| IL (1) | IL187161A0 (pt) |
| MX (1) | MX2007014597A (pt) |
| NO (1) | NO20076390L (pt) |
| WO (1) | WO2006127477A2 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491394B2 (en) | 2001-02-15 | 2009-02-17 | The Board Of Trustees Of The University Of Illinois | Cytotoxic factors for modulating cell death |
| KR20080024124A (ko) * | 2005-05-20 | 2008-03-17 | 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 | 쿠프레독신과 시토크롬 ｃ로 ｈｉｖ 감염을 치료하기 위한조성물과 방법 |
| WO2007012004A2 (en) | 2005-07-19 | 2007-01-25 | The Board Of Trustees Of The University Of Illinois | Transport agents for crossing the blood-brain barrier and into brain cancer cells, and methods of use thereof |
| WO2007024368A2 (en) * | 2005-07-19 | 2007-03-01 | The Board Of Trustees Of The University Of Illinois | Compositions and methods to control angiogenesis with cupredoxins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491394B2 (en) * | 2001-02-15 | 2009-02-17 | The Board Of Trustees Of The University Of Illinois | Cytotoxic factors for modulating cell death |
| US20030059436A1 (en) * | 2001-03-02 | 2003-03-27 | St. Elizabeth's Medical Center, Inc. | Band 3 antigenic peptides, malaria polypeptides and uses thereof |
-
2006
- 2006-05-19 BR BRPI0612456-9A patent/BRPI0612456A2/pt not_active IP Right Cessation
- 2006-05-19 CA CA002607739A patent/CA2607739A1/en not_active Abandoned
- 2006-05-19 JP JP2008512549A patent/JP2009504567A/ja active Pending
- 2006-05-19 WO PCT/US2006/019492 patent/WO2006127477A2/en not_active Ceased
- 2006-05-19 AU AU2006251742A patent/AU2006251742A1/en not_active Abandoned
- 2006-05-19 MX MX2007014597A patent/MX2007014597A/es active IP Right Grant
- 2006-05-19 EP EP06770687A patent/EP1882039A4/en not_active Withdrawn
- 2006-05-19 KR KR1020077028985A patent/KR20080019615A/ko not_active Ceased
-
2007
- 2007-11-05 IL IL187161A patent/IL187161A0/en unknown
- 2007-12-11 NO NO20076390A patent/NO20076390L/no not_active Application Discontinuation
-
2010
- 2010-04-06 AU AU2010201360A patent/AU2010201360A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080019615A (ko) | 2008-03-04 |
| EP1882039A2 (en) | 2008-01-30 |
| WO2006127477A3 (en) | 2007-03-08 |
| MX2007014597A (es) | 2008-01-21 |
| NO20076390L (no) | 2008-02-15 |
| WO2006127477A2 (en) | 2006-11-30 |
| JP2009504567A (ja) | 2009-02-05 |
| AU2010201360A1 (en) | 2010-04-29 |
| CA2607739A1 (en) | 2006-11-30 |
| EP1882039A4 (en) | 2008-08-20 |
| AU2006251742A1 (en) | 2006-11-30 |
| IL187161A0 (en) | 2008-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 6A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012. |