BRPI0612897A2 - método para produzir um antígeno covalentemente estabilizado - Google Patents
método para produzir um antígeno covalentemente estabilizadoInfo
- Publication number
- BRPI0612897A2 BRPI0612897A2 BRPI0612897A BRPI0612897A BRPI0612897A2 BR PI0612897 A2 BRPI0612897 A2 BR PI0612897A2 BR PI0612897 A BRPI0612897 A BR PI0612897A BR PI0612897 A BRPI0612897 A BR PI0612897A BR PI0612897 A2 BRPI0612897 A2 BR PI0612897A2
- Authority
- BR
- Brazil
- Prior art keywords
- produce
- covalently stabilized
- stabilized antigen
- antigen
- covalently
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69552805P | 2005-06-30 | 2005-06-30 | |
| PCT/US2006/024742 WO2007005358A2 (en) | 2005-06-30 | 2006-06-26 | Method for preparing a covalently cross linked oligomer of amyloid beta peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0612897A2 true BRPI0612897A2 (pt) | 2016-11-29 |
Family
ID=37478826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0612897A BRPI0612897A2 (pt) | 2005-06-30 | 2006-06-26 | método para produzir um antígeno covalentemente estabilizado |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100143396A1 (pt) |
| EP (1) | EP1899371A2 (pt) |
| JP (1) | JP2009500325A (pt) |
| CN (1) | CN101213207A (pt) |
| AR (1) | AR055584A1 (pt) |
| AU (1) | AU2006266212A1 (pt) |
| BR (1) | BRPI0612897A2 (pt) |
| CA (1) | CA2613040A1 (pt) |
| TW (1) | TW200726482A (pt) |
| WO (1) | WO2007005358A2 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002003911A2 (en) | 2000-07-07 | 2002-01-17 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
| EP2289909B1 (en) | 2005-11-30 | 2014-10-29 | AbbVie Inc. | Screening method, process for purifying of non-diffusible a-beta oligomers, selective antibodies against said non-diffusible a-beta oligomers and a process for manufacturing of said antibodies |
| KR101667623B1 (ko) | 2005-11-30 | 2016-10-19 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도 |
| SI2004688T2 (sl) | 2006-03-23 | 2014-05-30 | Bioarctic Neuroscience Ab | Izboljšana protofibrilno selektivna protitelesa in njihova uporaba |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2486928A1 (en) | 2007-02-27 | 2012-08-15 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| FR2922769A1 (fr) * | 2007-10-31 | 2009-05-01 | Halina Malina | Modification des sequences intrinsequement desordonnees pour la preparation de vaccins |
| JP5817060B2 (ja) | 2008-04-14 | 2015-11-18 | アルツィノヴァ エービー | 精製されたペプチド、精製されたペプチドを含む可溶性オリゴマー、精製されたペプチドあるいは可溶性オリゴマーを利用した、疾患の治療に適した化合物の同定方法、精製されたペプチドあるいは可溶性オリゴマーを利用した、精製されたペプチドあるいは可溶性オリゴマーと反応する結合タンパク質の選択方法、医薬組成物の製造における、精製されたペプチドあるいは可溶性オリゴマーの使用、精製されたペプチドあるいは可溶性オリゴマーを含む医薬製剤、精製されたペプチドあるいは可溶性オリゴマーを含むワクチン、精製されたペプチドあるいは可溶性オリゴマーを利用した、ヒトを除く哺乳動物を予防または治療する方法、appが二つのシステインを含むappをコードするヌクレオチドを発現する、非ヒトトランスジェニック動物、精製されたペプチドをコードするヌクレオチドを発現する、非ヒトトランスジェニック動物、appが二つのシステインを含むappであるポリペプチド、精製されたペプチドまたはポリペプチドをコードするヌクレオチド、精製されたペプチドまたはポリペプチドをコードするヌクレオチドを含む発現系 |
| EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
| JP5934203B2 (ja) | 2010-07-14 | 2016-06-15 | メルク・シャープ・エンド・ドーム・コーポレイション | 抗addlモノクローナル抗体およびこの使用 |
| MX358739B (es) | 2010-08-14 | 2018-09-03 | Abbvie Inc Star | Proteinas de union a amiloide beta. |
| US9573994B2 (en) | 2014-07-10 | 2017-02-21 | Bioarctic Neuroscience Ab | Aβ protofibril binding antibodies |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003074004A2 (en) * | 2002-03-01 | 2003-09-12 | Szu-Yi Chou | Method of producing antigens |
-
2006
- 2006-06-22 TW TW095122531A patent/TW200726482A/zh unknown
- 2006-06-23 AR ARP060102726A patent/AR055584A1/es not_active Application Discontinuation
- 2006-06-26 BR BRPI0612897A patent/BRPI0612897A2/pt not_active IP Right Cessation
- 2006-06-26 US US11/922,552 patent/US20100143396A1/en not_active Abandoned
- 2006-06-26 AU AU2006266212A patent/AU2006266212A1/en not_active Abandoned
- 2006-06-26 EP EP06785554A patent/EP1899371A2/en not_active Withdrawn
- 2006-06-26 CA CA002613040A patent/CA2613040A1/en not_active Abandoned
- 2006-06-26 WO PCT/US2006/024742 patent/WO2007005358A2/en not_active Ceased
- 2006-06-26 CN CNA2006800235119A patent/CN101213207A/zh active Pending
- 2006-06-26 JP JP2008519442A patent/JP2009500325A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009500325A (ja) | 2009-01-08 |
| WO2007005358A3 (en) | 2007-04-05 |
| CA2613040A1 (en) | 2007-01-11 |
| AR055584A1 (es) | 2007-08-29 |
| EP1899371A2 (en) | 2008-03-19 |
| CN101213207A (zh) | 2008-07-02 |
| AU2006266212A1 (en) | 2007-01-11 |
| TW200726482A (en) | 2007-07-16 |
| WO2007005358A2 (en) | 2007-01-11 |
| US20100143396A1 (en) | 2010-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO NO ORIGINAL, TRASLADO OU FOTOCOPIA AUTENTICADA. |
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| B11Z | Dismissal: petition dismissal - article 216, par 2 of industrial property law |
Free format text: REFERENTE A PETICAO NO 20070185025/RJ DE 28/12/2007. |
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| B11M | Decision cancelled [chapter 11.13 patent gazette] |
Free format text: O DESPACHO 11.6.1 ESTA SENDO ANULADO TENDO POR BASE A DETERMINACAO DO DIRETOR DE PATENTES, A QUAL E CALCADA NO PARECER NO 0003-2014 AGU/PGF/PFE/INPI/COOPHI-LBC-1.0. |
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| B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] |
Free format text: O DESPACHO 6.7 ESTA SENDO ANULADO TENDO POR BASE A DETERMINACAO DO DIRETOR DE PATENTES, A QUAL E CALCADA NO PARECER NO 0003-2014 AGU/PGF/PFE/INPI/COOPHI-LBC-1.0. |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A, 7A, 8A, 9A E 10A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 39/00 (2006.01), A61K 47/64 (2017.01) |
|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |