CY2019041I2 - Τροποποιημενα αντισωματα εναντι il-23 - Google Patents
Τροποποιημενα αντισωματα εναντι il-23Info
- Publication number
- CY2019041I2 CY2019041I2 CY2019041C CY2019041C CY2019041I2 CY 2019041 I2 CY2019041 I2 CY 2019041I2 CY 2019041 C CY2019041 C CY 2019041C CY 2019041 C CY2019041 C CY 2019041C CY 2019041 I2 CY2019041 I2 CY 2019041I2
- Authority
- CY
- Cyprus
- Prior art keywords
- antibodies against
- modified antibodies
- modified
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71358505P | 2005-08-31 | 2005-08-31 | |
| PCT/US2006/033764 WO2007027714A2 (en) | 2005-08-31 | 2006-08-29 | Engineered anti-il-23 antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CY2019041I1 CY2019041I1 (el) | 2020-05-29 |
| CY2019041I2 true CY2019041I2 (el) | 2020-05-29 |
Family
ID=37685722
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20171100342T CY1118760T1 (el) | 2005-08-31 | 2017-03-17 | Τροποποιημενα αντισωματα εναντι il-23 |
| CY2019041C CY2019041I2 (el) | 2005-08-31 | 2019-10-25 | Τροποποιημενα αντισωματα εναντι il-23 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20171100342T CY1118760T1 (el) | 2005-08-31 | 2017-03-17 | Τροποποιημενα αντισωματα εναντι il-23 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US7807160B2 (el) |
| EP (3) | EP1931710B1 (el) |
| JP (2) | JP5350793B2 (el) |
| CN (1) | CN101296944A (el) |
| CA (1) | CA2620802A1 (el) |
| CY (2) | CY1118760T1 (el) |
| DK (1) | DK1931710T3 (el) |
| ES (1) | ES2619845T3 (el) |
| HR (1) | HRP20170444T1 (el) |
| HU (2) | HUE032131T2 (el) |
| LT (2) | LT1931710T (el) |
| ME (1) | ME02705B (el) |
| PL (1) | PL1931710T3 (el) |
| PT (1) | PT1931710T (el) |
| RS (1) | RS55788B1 (el) |
| SG (2) | SG10201402712QA (el) |
| WO (1) | WO2007027714A2 (el) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2452694B1 (en) * | 2005-06-30 | 2018-11-14 | Janssen Biotech, Inc. | Anti-IL-23 antibodies, compositions, methods and uses |
| LT1931710T (lt) | 2005-08-31 | 2017-03-27 | Merck Sharp & Dohme Corp. | Rekombinantiniai anti-il-23 antikūnai |
| SI1933869T1 (sl) | 2005-09-01 | 2010-02-26 | Schering Corp | Uporaba IL-23 in IL-17 antagonistov za zdravljenje avtoimunske očesne vnetne bolezni |
| AU2006342792A1 (en) * | 2005-12-02 | 2007-11-08 | Genentech, Inc. | Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to IL-22 and IL-22R |
| RS55963B1 (sr) | 2005-12-29 | 2017-09-29 | Janssen Biotech Inc | Humana anti-il-23 antitela, kompozicije, metode i upotrebe |
| US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| WO2007147019A2 (en) * | 2006-06-13 | 2007-12-21 | Zymogenetics, Inc. | Il-17 and il-23 antagonists and methods of using the same |
| US8414897B1 (en) * | 2006-10-02 | 2013-04-09 | The Uab Research Foundation | Pathway for Th-17 cell development and methods utilizing same |
| TWI426918B (zh) | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
| DK2426144T3 (en) | 2007-02-23 | 2019-01-07 | Merck Sharp & Dohme | Manipulated Anti-IL-23P19 Antibodies |
| SG178804A1 (en) * | 2007-02-23 | 2012-03-29 | Schering Corp | Engineered anti-il-23p19 antibodies |
| NZ579251A (en) | 2007-02-28 | 2012-06-29 | Schering Corp | Engineered anti-il-23r antibodies |
| CA2679400A1 (en) * | 2007-02-28 | 2008-09-04 | Schering Corporation | Combination therapy for treatment of immune disorders |
| US7981415B2 (en) * | 2007-09-07 | 2011-07-19 | Cisthera, Inc. | Humanized PAI-1 antibodies |
| US7771720B2 (en) * | 2007-09-07 | 2010-08-10 | Cisthera, Inc. | Humanized PAI-1 antibodies |
| US20100203009A1 (en) * | 2007-10-02 | 2010-08-12 | The Uab Research Foundation | Pathway for Th-17 Cell Development and Methods Utilizing Same |
| AR068723A1 (es) * | 2007-10-05 | 2009-12-02 | Glaxo Group Ltd | Proteina que se une a antigenos que se une a il-23 humana y sus usos |
| AU2009204441B2 (en) | 2008-01-09 | 2015-03-05 | The Schepens Eye Research Institute, Inc. | Therapeutic compositions for treatment of ocular inflammatory disorders |
| KR20160116056A (ko) | 2008-08-14 | 2016-10-06 | 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 | 항-il-12/il-23 항체 |
| EP2331078B1 (en) | 2008-08-27 | 2012-09-19 | Merck Sharp & Dohme Corp. | Lyophilized formulations of engineered anti-il-23p19 antibodies |
| JP5564049B2 (ja) * | 2008-09-29 | 2014-07-30 | ヤンセン バイオテツク,インコーポレーテツド | 抗cd147抗体、方法及び使用 |
| MX2011006549A (es) | 2008-12-19 | 2011-07-20 | Schering Corp | Suplemento alimenticio para el cultivo de celula de mamifero y metodos de uso. |
| WO2010127181A1 (en) | 2009-04-29 | 2010-11-04 | Trellis Bioscience, Inc. | Improved antibodies immunoreactive with heregulin-coupled her3 |
| US20120269765A1 (en) * | 2009-07-24 | 2012-10-25 | Garcia K Christopher | Cytokine compositions and methods of use thereof |
| JO3244B1 (ar) * | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| SG177025A1 (en) * | 2010-06-21 | 2012-01-30 | Agency Science Tech & Res | Hepatitis b virus specific antibody and uses thereof |
| EP4349868A3 (en) * | 2010-05-14 | 2024-08-28 | The Board of Trustees of the Leland Stanford Junior University | Humanized and chimeric monoclonal antibodies to cd47 |
| US20110311527A1 (en) | 2010-06-16 | 2011-12-22 | Allergan, Inc. | IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS |
| CA2805653A1 (en) * | 2010-07-20 | 2012-01-26 | Cephalon Australia Pty Ltd | Anti-il-23 heterodimer specific antibodies |
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| EP2675467A4 (en) * | 2011-02-18 | 2014-06-25 | Merck Sharp & Dohme | USE OF MDL-1 ANTAGONISTS FOR THE TREATMENT OF SPONDYLARTHROPATHY |
| EP2583979B1 (en) | 2011-10-19 | 2015-12-16 | Effimune | Methods to prepare antibodies directed against p19 subunit of human IL-23 |
| EA034778B1 (ru) | 2012-02-06 | 2020-03-19 | Инхибркс, Инк. | Антитела к cd47 и способы их применения |
| CN104507497B (zh) | 2012-05-03 | 2018-10-19 | 勃林格殷格翰国际有限公司 | 抗IL-23p19抗体 |
| ES2711554T3 (es) | 2012-05-22 | 2019-05-06 | Bristol Myers Squibb Co | Anticuerpos biespecíficos contra IL-17A/F IL-23 y sus usos |
| EP2866833B1 (en) | 2012-06-27 | 2019-05-15 | Merck Sharp & Dohme Corp. | Crystalline anti-human il-23 antibodies |
| CA2881966C (en) | 2012-08-24 | 2020-10-06 | The Regents Of The University Of California | Antibodies and vaccines for use in treating ror1 cancers and inhibiting metastasis |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| TWI636063B (zh) * | 2013-03-08 | 2018-09-21 | 美國禮來大藥廠 | 結合il-23之抗體 |
| CN105307675A (zh) | 2013-03-15 | 2016-02-03 | 美国安进公司 | 使用抗il23抗体治疗克罗恩氏病的方法 |
| CN105209064A (zh) | 2013-03-15 | 2015-12-30 | 美国安进公司 | 使用抗il-23抗体治疗银屑病的方法 |
| PT3038650T (pt) | 2013-08-30 | 2021-08-25 | Immunogen Inc | Anticorpos e ensaios para a deteção do recetor de folato 1 |
| TWI713453B (zh) | 2014-06-23 | 2020-12-21 | 美商健生生物科技公司 | 干擾素α及ω抗體拮抗劑 |
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| AR102417A1 (es) | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
| SG10202103879YA (en) | 2015-02-04 | 2021-05-28 | Boehringer Ingelheim Int | Methods of treating inflammatory diseases |
| JP2018511346A (ja) | 2015-03-31 | 2018-04-26 | ブイエイチスクエアード リミテッド | ポリペプチド |
| KR102789821B1 (ko) | 2015-03-31 | 2025-04-02 | 소리소 파마슈티컬스 인크. | 프로테아제-절단가능 링커를 갖는 펩티드 구조물 |
| MX2017013156A (es) | 2015-04-14 | 2018-02-21 | Boehringer Ingelheim Int | Metodos para tratar enfermedades. |
| US10576131B2 (en) | 2015-06-03 | 2020-03-03 | Affiris Ag | IL-23-p19 vaccines |
| JP6880006B2 (ja) | 2015-09-17 | 2021-06-02 | イミュノジェン, インコーポレイテッド | 抗folr1免疫複合体を含む治療組み合わせ |
| HK1258292A1 (zh) | 2015-09-17 | 2019-11-08 | Amgen Inc. | 使用il23途径生物标志物预测il23拮抗剂的临床应答 |
| TWI733695B (zh) * | 2015-09-18 | 2021-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 治療發炎性疾病之方法 |
| KR20250099459A (ko) * | 2015-11-03 | 2025-07-01 | 얀센 바이오테크 인코포레이티드 | Pd-1과 특이적으로 결합하는 항체 및 그의 용도 |
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| EP3474854A4 (en) | 2016-06-27 | 2020-02-19 | The Regents of The University of California | CANCER TREATMENT COMBINATIONS |
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| CN114514243B (zh) | 2019-06-21 | 2025-01-24 | 索瑞索制药公司 | 多肽 |
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| EP4077378A1 (en) | 2019-12-20 | 2022-10-26 | NovaRock Biotherapeutics, Ltd. | Anti-interleukin-23 p19 antibodies and methods of use thereof |
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- 2006-08-29 WO PCT/US2006/033764 patent/WO2007027714A2/en not_active Ceased
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| CN101296944A (zh) | 2008-10-29 |
| CY2019041I1 (el) | 2020-05-29 |
| US20070048315A1 (en) | 2007-03-01 |
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| SG10201402712QA (en) | 2014-08-28 |
| WO2007027714A3 (en) | 2007-06-21 |
| DK1931710T3 (en) | 2017-04-03 |
| US8362212B2 (en) | 2013-01-29 |
| SG165322A1 (en) | 2010-10-28 |
| EP3190125A1 (en) | 2017-07-12 |
| PL1931710T3 (pl) | 2017-06-30 |
| ME02705B (me) | 2017-10-20 |
| HUE032131T2 (en) | 2017-09-28 |
| HRP20170444T1 (hr) | 2017-05-19 |
| JP2011130771A (ja) | 2011-07-07 |
| EP1931710A2 (en) | 2008-06-18 |
| CA2620802A1 (en) | 2007-03-08 |
| RS55788B1 (sr) | 2017-08-31 |
| LTPA2019520I1 (lt) | 2019-11-11 |
| WO2007027714A2 (en) | 2007-03-08 |
| US20090156788A1 (en) | 2009-06-18 |
| EP1931710B1 (en) | 2017-01-18 |
| PT1931710T (pt) | 2017-03-28 |
| CY1118760T1 (el) | 2017-07-12 |
| JP2009505677A (ja) | 2009-02-12 |
| ES2619845T3 (es) | 2017-06-27 |
| HUS1900050I1 (hu) | 2019-11-28 |
| LT1931710T (lt) | 2017-03-27 |
| US7807160B2 (en) | 2010-10-05 |
| US20110002942A1 (en) | 2011-01-06 |
| EP2354160A1 (en) | 2011-08-10 |
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