BRPI0614417A2 - composições farmacêuticas compreendendo bloqueadores de canais de cálcio de dihidropiridina e ácidos graxos de Èmega-3 e métodos de tratamento utilizando as mesmas - Google Patents
composições farmacêuticas compreendendo bloqueadores de canais de cálcio de dihidropiridina e ácidos graxos de Èmega-3 e métodos de tratamento utilizando as mesmas Download PDFInfo
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- BRPI0614417A2 BRPI0614417A2 BRPI0614417-9A BRPI0614417A BRPI0614417A2 BR PI0614417 A2 BRPI0614417 A2 BR PI0614417A2 BR PI0614417 A BRPI0614417 A BR PI0614417A BR PI0614417 A2 BRPI0614417 A2 BR PI0614417A2
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- pharmaceutical composition
- omega
- channel blockers
- calcium channel
- fatty acids
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- 239000002866 dihydropyridine calcium channel blocker Substances 0.000 title claims abstract description 70
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Classifications
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- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70300205P | 2005-07-28 | 2005-07-28 | |
| US60/703,002 | 2005-07-28 | ||
| PCT/US2006/029217 WO2007016256A2 (en) | 2005-07-28 | 2006-07-28 | Treatment with dihydropyridine calcium channel blockers and omega-3 fatty acids and a combination product thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0614417A2 true BRPI0614417A2 (pt) | 2011-03-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0614417-9A BRPI0614417A2 (pt) | 2005-07-28 | 2006-07-28 | composições farmacêuticas compreendendo bloqueadores de canais de cálcio de dihidropiridina e ácidos graxos de Èmega-3 e métodos de tratamento utilizando as mesmas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20070196465A1 (de) |
| EP (1) | EP1919285A2 (de) |
| JP (1) | JP2009502950A (de) |
| KR (1) | KR20080030691A (de) |
| CN (1) | CN101252837A (de) |
| AU (1) | AU2006275784A1 (de) |
| BR (1) | BRPI0614417A2 (de) |
| CA (1) | CA2616806A1 (de) |
| EA (1) | EA200800451A1 (de) |
| MX (1) | MX2008001282A (de) |
| NO (1) | NO20081067L (de) |
| WO (1) | WO2007016256A2 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2081550B2 (de) * | 2006-03-09 | 2021-05-26 | Reliant Pharmaceuticals, Inc. | Beschichtung von kapseln mit pharmazeutischen wirkstoffen |
| US8784886B2 (en) * | 2006-03-09 | 2014-07-22 | GlaxoSmithKline, LLC | Coating capsules with active pharmaceutical ingredients |
| EP3050568B1 (de) | 2007-03-13 | 2020-12-02 | JDS Therapeutics, LLC | Verfahren und zusammensetzungen zur verzögerten freisetzung von chrom |
| WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
| WO2010014727A1 (en) * | 2008-08-01 | 2010-02-04 | The Medicines Company | Pharmaceutical compositions and methods for producing low impurity concentrations of the same |
| CN102186351A (zh) * | 2008-08-01 | 2011-09-14 | 医药公司 | 药物组合物和用于稳定药物组合物的方法 |
| WO2010028067A1 (en) | 2008-09-02 | 2010-03-11 | Amarin Corporation Plc | Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same |
| KR101383006B1 (ko) | 2009-02-10 | 2014-04-08 | 아마린 파마, 인크. | 고중성지방혈증 치료 방법 |
| PT3278665T (pt) | 2009-04-29 | 2020-11-19 | Amarin Pharmaceuticals Ie Ltd | Composição farmacêutica estável e métodos de utilização das mesmas |
| SG175390A1 (en) | 2009-04-29 | 2011-12-29 | Amarin Corp Plc | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| CN106074486A (zh) | 2009-06-15 | 2016-11-09 | 阿马里纳药物爱尔兰有限公司 | 在相伴他汀类疗法的对象中降低甘油三酯、没有增加ldl‑c水平的组合物和方法 |
| US20110071176A1 (en) | 2009-09-23 | 2011-03-24 | Amarin Pharma, Inc. | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same |
| ES2363964B1 (es) | 2009-11-20 | 2012-08-22 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados. |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| NZ778131A (en) | 2010-11-29 | 2023-03-31 | Amarin Pharmaceuticals Ie Ltd | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| US8951514B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels |
| US8715648B2 (en) | 2011-02-16 | 2014-05-06 | Pivotal Therapeutics Inc. | Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics |
| US8952000B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events |
| US9119826B2 (en) | 2011-02-16 | 2015-09-01 | Pivotal Therapeutics, Inc. | Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels |
| KR101310710B1 (ko) * | 2011-03-23 | 2013-09-27 | 한미약품 주식회사 | 오메가-3 지방산 에스테르 및 ＨＭＧ-ＣｏＡ 환원효소 억제제를 포함하는 경구용 복합 조성물 |
| EP2775837A4 (de) | 2011-11-07 | 2015-10-28 | Amarin Pharmaceuticals Ie Ltd | Verfahren zur behandlung von hypertriglyceridämie |
| US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
| ES2891473T3 (es) | 2012-01-06 | 2022-01-28 | Amarin Pharmaceuticals Ie Ltd | Composiciones y métodos para reducir los niveles de alta sensibilidad (hs-CRP) en un sujeto |
| EP2861227A4 (de) | 2012-06-17 | 2016-01-27 | Matinas Biopharma Inc | Omega-3 pentaensäurezusammensetzungen und verfahren zur verwendung |
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| KR20210110890A (ko) | 2018-09-24 | 2021-09-09 | 애머린 파마슈티칼스 아일랜드 리미티드 | 대상체에서 심혈관 사건의 위험도를 감소시키는 방법 |
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| AU2022263358A1 (en) | 2021-04-21 | 2023-11-30 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of heart failure |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8819110D0 (en) * | 1988-08-11 | 1988-09-14 | Norsk Hydro As | Antihypertensive drug & method for production |
| US5186942A (en) * | 1989-01-30 | 1993-02-16 | Alza Corporation | Nicardipine therapy |
| US5162325A (en) * | 1991-05-07 | 1992-11-10 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted benzyl element |
| DE4322826A1 (de) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmazeutisches Präparat |
| TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
| IL156585A0 (en) * | 2001-01-26 | 2004-01-04 | Schering Corp | Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions |
| JP4421804B2 (ja) * | 2002-03-25 | 2010-02-24 | 日本メナード化粧品株式会社 | 高血圧抑制剤 |
| US7759507B2 (en) * | 2003-09-05 | 2010-07-20 | Abbott Laboratories | Lipid system and methods of use |
| US8784886B2 (en) * | 2006-03-09 | 2014-07-22 | GlaxoSmithKline, LLC | Coating capsules with active pharmaceutical ingredients |
-
2006
- 2006-07-28 MX MX2008001282A patent/MX2008001282A/es unknown
- 2006-07-28 KR KR1020087004930A patent/KR20080030691A/ko not_active Withdrawn
- 2006-07-28 EP EP06788670A patent/EP1919285A2/de not_active Withdrawn
- 2006-07-28 BR BRPI0614417-9A patent/BRPI0614417A2/pt not_active Application Discontinuation
- 2006-07-28 US US11/494,799 patent/US20070196465A1/en not_active Abandoned
- 2006-07-28 CN CNA2006800318145A patent/CN101252837A/zh active Pending
- 2006-07-28 CA CA002616806A patent/CA2616806A1/en not_active Abandoned
- 2006-07-28 EA EA200800451A patent/EA200800451A1/ru unknown
- 2006-07-28 WO PCT/US2006/029217 patent/WO2007016256A2/en not_active Ceased
- 2006-07-28 AU AU2006275784A patent/AU2006275784A1/en not_active Abandoned
- 2006-07-28 JP JP2008524148A patent/JP2009502950A/ja active Pending
-
2008
- 2008-02-28 NO NO20081067A patent/NO20081067L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA200800451A1 (ru) | 2008-08-29 |
| NO20081067L (no) | 2008-04-18 |
| EP1919285A2 (de) | 2008-05-14 |
| WO2007016256A2 (en) | 2007-02-08 |
| CA2616806A1 (en) | 2007-02-08 |
| US20070196465A1 (en) | 2007-08-23 |
| MX2008001282A (es) | 2008-03-24 |
| AU2006275784A1 (en) | 2007-02-08 |
| JP2009502950A (ja) | 2009-01-29 |
| WO2007016256A3 (en) | 2007-07-12 |
| KR20080030691A (ko) | 2008-04-04 |
| CN101252837A (zh) | 2008-08-27 |
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