BRPI0615096A2 - análogos de indenoisoquinolinona e métodos de uso dos mesmos - Google Patents

análogos de indenoisoquinolinona e métodos de uso dos mesmos

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Publication number
BRPI0615096A2
BRPI0615096A2 BRPI0615096-9A BRPI0615096A BRPI0615096A2 BR PI0615096 A2 BRPI0615096 A2 BR PI0615096A2 BR PI0615096 A BRPI0615096 A BR PI0615096A BR PI0615096 A2 BRPI0615096 A2 BR PI0615096A2
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BR
Brazil
Prior art keywords
indenoisoquinolinone
disease
methods
effective amount
analogues
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Application number
BRPI0615096-9A
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English (en)
Inventor
Prakash Jagtap
Duy-Phong Pham-Huu
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Inotek Pharmaceuticals Corp
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Publication date
Application filed by Inotek Pharmaceuticals Corp filed Critical Inotek Pharmaceuticals Corp
Publication of BRPI0615096A2 publication Critical patent/BRPI0615096A2/pt

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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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Abstract

ANáLOGOS DE INDENOISOQUINOLINONA E MéTODOS DE USO DOS MESMOS. A presente invenção refere-se a análogos de indenoisoquinolinona, composições compreendendo uma quantidade eficaz de um análogo de indenoisoquinolinona e métodos para tratar ou prevenir uma doença inflamatória, uma lesão de reperfusão, diabetes melito, uma complicação diabética, uma lesão por reoxigenação resultante de transplante de órgão, uma condição isquêmica, uma doença neurodegenerativa, insuficiência renal, uma doença vascular, uma doença cardiovascular, câncer, uma complicação de prematuridade, cardiomiopatia, retinopatia, nefropatia, neuropatia, disfunção erétil ou incontinência urinária, compreendendo administrar a um indivíduo com necessidade do mesmo uma quantidade eficaz de um análogo de indenoisoquinolinona.
BRPI0615096-9A 2005-08-24 2006-08-23 análogos de indenoisoquinolinona e métodos de uso dos mesmos BRPI0615096A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71076905P 2005-08-24 2005-08-24
PCT/US2006/033018 WO2007025009A2 (en) 2005-08-24 2006-08-23 Indenoisoquinolinone analogs and methods of use thereof

Publications (1)

Publication Number Publication Date
BRPI0615096A2 true BRPI0615096A2 (pt) 2009-07-14

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BRPI0615096-9A BRPI0615096A2 (pt) 2005-08-24 2006-08-23 análogos de indenoisoquinolinona e métodos de uso dos mesmos

Country Status (12)

Country Link
US (2) US7652028B2 (pt)
EP (1) EP1937268A4 (pt)
JP (1) JP2009506060A (pt)
KR (1) KR20080039508A (pt)
CN (1) CN101316592A (pt)
AU (1) AU2006283078A1 (pt)
BR (1) BRPI0615096A2 (pt)
CA (1) CA2620052A1 (pt)
IL (1) IL189602A0 (pt)
RU (1) RU2008110955A (pt)
WO (1) WO2007025009A2 (pt)
ZA (1) ZA200802501B (pt)

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CN102482282A (zh) * 2009-08-26 2012-05-30 赛福伦公司 多环化合物的新形式
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US7652028B2 (en) 2010-01-26
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US20070049555A1 (en) 2007-03-01
CN101316592A (zh) 2008-12-03
JP2009506060A (ja) 2009-02-12
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