BRPI0615717A2 - inibição da expressão do gene viral usando pequeno rna interferente - Google Patents
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- BRPI0615717A2 BRPI0615717A2 BRPI0615717-3A BRPI0615717A BRPI0615717A2 BR PI0615717 A2 BRPI0615717 A2 BR PI0615717A2 BR PI0615717 A BRPI0615717 A BR PI0615717A BR PI0615717 A2 BRPI0615717 A2 BR PI0615717A2
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- C12N2310/111—Antisense spanning the whole gene, or a large part of it
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- C—CHEMISTRY; METALLURGY
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US2005/032768 | 2005-09-12 | ||
| PCT/US2005/032768 WO2006031901A2 (en) | 2004-09-10 | 2005-09-12 | SMALL INTERFERING RNAs THAT EFFICIENTLY INHIBIT VIRAL GENE EXPRESSION AND METHODS OF USE THEREOF |
| PCT/US2006/021253 WO2007032794A2 (en) | 2005-09-12 | 2006-06-01 | Inhibition of viral gene expression using small interfering rna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0615717A2 true BRPI0615717A2 (pt) | 2011-05-24 |
Family
ID=37708176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0615717-3A BRPI0615717A2 (pt) | 2005-09-12 | 2006-06-01 | inibição da expressão do gene viral usando pequeno rna interferente |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1979480A2 (de) |
| JP (1) | JP2009521207A (de) |
| KR (1) | KR20090003147A (de) |
| CN (2) | CN101305095B (de) |
| AU (1) | AU2006291568A1 (de) |
| BR (1) | BRPI0615717A2 (de) |
| CA (1) | CA2622242A1 (de) |
| RU (1) | RU2008114304A (de) |
| WO (1) | WO2007032794A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009042115A2 (en) * | 2007-09-24 | 2009-04-02 | Rosetta Inpharmatics Llc | Methods of designing short hairpin rnas (shrnas) for gene silencing |
| DK2341943T3 (en) * | 2008-09-22 | 2019-02-25 | Dicerna Pharmaceuticals Inc | COMPOSITIONS AND METHODS OF SPECIFIC INHIBITION OF DSRNA REPRINT WITH MODIFICATIONS |
| JP2012505657A (ja) | 2008-10-15 | 2012-03-08 | ソマジェニックス インク． | 遺伝子発現の阻害のためのショートヘアピンｒｎａ |
| KR101728655B1 (ko) * | 2008-12-18 | 2017-04-19 | 다이서나 파마수이티컬, 인크. | 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법 |
| EP2454371B1 (de) | 2009-07-13 | 2021-01-20 | Somagenics, Inc. | Chemische modifikation kleiner haarnadel-rnas zur genexpressionshemmung |
| US9029341B2 (en) * | 2010-08-17 | 2015-05-12 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA) |
| KR102545316B1 (ko) | 2014-11-10 | 2023-06-22 | 알닐람 파마슈티칼스 인코포레이티드 | Ｂ형 간염 바이러스(ｈｂｖ) ｉｒｎａ 조성물 및 그의 이용 방법 |
| KR101668954B1 (ko) | 2015-05-29 | 2016-10-24 | 연세대학교 산학협력단 | ＨＣＶ ＩＲＥＳ를 표적으로 하는 Ｃ형 간염 바이러스 치료제 siRNA |
| BR112019012057A2 (pt) | 2016-12-15 | 2019-11-12 | Meharry Medical College | agente antiviral, composição farmacêutica para a administração do mesmo e métodos de redução na replicação do vírus zika (zikv) e tratamento de doença mediada pelo vírus zika (zikv) |
| US11324820B2 (en) | 2017-04-18 | 2022-05-10 | Alnylam Pharmaceuticals, Inc. | Methods for the treatment of subjects having a hepatitis b virus (HBV) infection |
| JP7625512B2 (ja) | 2018-08-13 | 2025-02-03 | アルナイラム ファーマシューティカルズ， インコーポレイテッド | Ｂ型肝炎ウイルス（ＨＢＶ）ｄｓＲＮＡ物質組成物およびその使用方法 |
| KR102835107B1 (ko) * | 2021-03-25 | 2025-07-18 | 고려대학교 산학협력단 | 마이크로RNA 유사 활성을 가지는 코로나바이러스 감염증-19 예방 또는 치료용 siRNA 및 이를 포함하는 약학적 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003219817B2 (en) * | 2002-02-20 | 2006-08-31 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of hepatitis C virus |
| WO2006031901A2 (en) * | 2004-09-10 | 2006-03-23 | Somagenics, Inc. | SMALL INTERFERING RNAs THAT EFFICIENTLY INHIBIT VIRAL GENE EXPRESSION AND METHODS OF USE THEREOF |
| CN100344331C (zh) * | 2004-09-22 | 2007-10-24 | 广州拓谱基因技术有限公司 | 用于预防或治疗丙型肝炎的靶向小干扰rna制剂及其制备方法 |
-
2006
- 2006-06-01 EP EP06784525A patent/EP1979480A2/de not_active Withdrawn
- 2006-06-01 WO PCT/US2006/021253 patent/WO2007032794A2/en not_active Ceased
- 2006-06-01 KR KR1020087008905A patent/KR20090003147A/ko not_active Withdrawn
- 2006-06-01 RU RU2008114304/13A patent/RU2008114304A/ru unknown
- 2006-06-01 BR BRPI0615717-3A patent/BRPI0615717A2/pt not_active Application Discontinuation
- 2006-06-01 CN CN2006800418459A patent/CN101305095B/zh not_active Expired - Fee Related
- 2006-06-01 JP JP2008529981A patent/JP2009521207A/ja active Pending
- 2006-06-01 CA CA002622242A patent/CA2622242A1/en not_active Abandoned
- 2006-06-01 CN CN2012102773452A patent/CN102827841A/zh active Pending
- 2006-06-01 AU AU2006291568A patent/AU2006291568A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1979480A2 (de) | 2008-10-15 |
| CA2622242A1 (en) | 2007-03-22 |
| JP2009521207A (ja) | 2009-06-04 |
| CN101305095A (zh) | 2008-11-12 |
| RU2008114304A (ru) | 2009-11-20 |
| CN101305095B (zh) | 2012-09-26 |
| KR20090003147A (ko) | 2009-01-09 |
| CN102827841A (zh) | 2012-12-19 |
| WO2007032794A3 (en) | 2007-08-30 |
| AU2006291568A1 (en) | 2007-03-22 |
| WO2007032794A2 (en) | 2007-03-22 |
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