BRPI0620895B8 - sistema para a ruptura de ligações que sustentam porções de tecido mole juntas - Google Patents

sistema para a ruptura de ligações que sustentam porções de tecido mole juntas

Info

Publication number
BRPI0620895B8
BRPI0620895B8 BRPI0620895A BRPI0620895A BRPI0620895B8 BR PI0620895 B8 BRPI0620895 B8 BR PI0620895B8 BR PI0620895 A BRPI0620895 A BR PI0620895A BR PI0620895 A BRPI0620895 A BR PI0620895A BR PI0620895 B8 BRPI0620895 B8 BR PI0620895B8
Authority
BR
Brazil
Prior art keywords
tissue
soft tissue
hold portions
breaking connections
tissue together
Prior art date
Application number
BRPI0620895A
Other languages
English (en)
Inventor
C Huculak John
W Kovalcheck Steven
Original Assignee
Alcon Inc
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc, Novartis Ag filed Critical Alcon Inc
Publication of BRPI0620895A2 publication Critical patent/BRPI0620895A2/pt
Publication of BRPI0620895B1 publication Critical patent/BRPI0620895B1/pt
Publication of BRPI0620895B8 publication Critical patent/BRPI0620895B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00736Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)

Abstract

sistema para a ruptura de ligações que sustentam porções de tecido mole juntas. a presente invenção refere-se a um aparelho e método para a dissociação de tecido protélco mole usando o fracionamento de fluxo de campo elétrico de energia de direção variável rápido e pulsado. o campo elétrico divisor rápido e pulsado é criado pelo uso de uma sonda que circunda o tecido protéico mole a ser removido. uma vez que o mecanismo adesivo entre os constituintes do tecido tenha sido comprometido, técnicas fluídicas são usadas para remover o tecido dissociado.
BRPI0620895A 2006-01-03 2006-12-11 sistema para a ruptura de ligações que sustentam porções de tecido mole juntas BRPI0620895B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75583906P 2006-01-03 2006-01-03
US60/755,839 2006-01-03
PCT/US2006/047185 WO2007081474A2 (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue

Publications (3)

Publication Number Publication Date
BRPI0620895A2 BRPI0620895A2 (pt) 2011-11-29
BRPI0620895B1 BRPI0620895B1 (pt) 2018-05-22
BRPI0620895B8 true BRPI0620895B8 (pt) 2021-06-22

Family

ID=38179730

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0620895A BRPI0620895B8 (pt) 2006-01-03 2006-12-11 sistema para a ruptura de ligações que sustentam porções de tecido mole juntas

Country Status (17)

Country Link
US (2) US7824870B2 (pt)
EP (1) EP1968470B1 (pt)
JP (1) JP5032500B2 (pt)
KR (1) KR101296325B1 (pt)
CN (1) CN101389280B (pt)
AR (1) AR058905A1 (pt)
AT (1) ATE466537T1 (pt)
AU (1) AU2006335194B2 (pt)
BR (1) BRPI0620895B8 (pt)
CA (1) CA2632970C (pt)
DE (1) DE602006014206D1 (pt)
ES (1) ES2342790T3 (pt)
IL (1) IL192344A (pt)
MX (1) MX2008008598A (pt)
RU (1) RU2419394C2 (pt)
TW (1) TWI360410B (pt)
WO (1) WO2007081474A2 (pt)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8109981B2 (en) * 2005-01-25 2012-02-07 Valam Corporation Optical therapies and devices
JP4616683B2 (ja) 2005-03-31 2011-01-19 富士通株式会社 情報処理装置、およびプログラム
JP5550909B2 (ja) * 2006-11-10 2014-07-16 ラーセン, ラース マイケル 眼の非破壊的或いは低破壊的光操作のための方法及び装置
WO2009026375A2 (en) * 2007-08-21 2009-02-26 Lehigh University Spermicidal and microbicidal compositions
US9402643B2 (en) 2008-01-15 2016-08-02 Novartis Ag Targeted illumination for surgical instrument
US8632534B2 (en) 2009-04-03 2014-01-21 Angiodynamics, Inc. Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US8083737B2 (en) 2009-08-26 2011-12-27 Tyco Healthcare Group Lp Gas-enhanced surgical instrument with mechanism for cylinder puncture
US8835166B2 (en) * 2009-09-04 2014-09-16 The Regents Of The University Of California Extracellular matrix material created using non-thermal irreversible electroporation
US20110118729A1 (en) 2009-11-13 2011-05-19 Alcon Research, Ltd High-intensity pulsed electric field vitrectomy apparatus with load detection
US20110118728A1 (en) 2009-11-13 2011-05-19 Alcon Research, Ltd. Control of high-intensity pulsed electrical fields in surgical applications
US20110118734A1 (en) 2009-11-16 2011-05-19 Alcon Research, Ltd. Capsularhexis device using pulsed electric fields
US20110135626A1 (en) * 2009-12-08 2011-06-09 Alcon Research, Ltd. Localized Chemical Lysis of Ocular Tissue
US20110144638A1 (en) * 2009-12-14 2011-06-16 Alcon Research, Ltd. Localized Shockwave-Induced Tissue Disruption
US20110144562A1 (en) * 2009-12-14 2011-06-16 Alcon Research, Ltd. Localized Pharmacological Treatment of Ocular Tissue Using High-Intensity Pulsed Electrical Fields
US20110144641A1 (en) * 2009-12-15 2011-06-16 Alcon Research, Ltd. High-Intensity Pulsed Electric Field Vitrectomy Apparatus
US8953651B2 (en) * 2010-02-24 2015-02-10 Alcon Lensx, Inc. High power femtosecond laser with repetition rate adjustable according to scanning speed
US20110288545A1 (en) * 2010-04-22 2011-11-24 Old Dominion University Research Foundation Method and Device for Ablation of Cancer and Resistance to New Cancer Growth
US10631912B2 (en) * 2010-04-30 2020-04-28 Medtronic Xomed, Inc. Interface module for use with nerve monitoring and electrosurgery
US8834462B2 (en) 2010-06-01 2014-09-16 Covidien Lp System and method for sensing tissue characteristics
US20160074221A1 (en) * 2010-06-14 2016-03-17 Marie-Jose B. Tassignon Femtosecond laser apparatus for plasma induced vitreous ablation in the eye
US9149388B2 (en) 2010-09-29 2015-10-06 Alcon Research, Ltd. Attenuated RF power for automated capsulorhexis
WO2012051433A2 (en) 2010-10-13 2012-04-19 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
US20130041355A1 (en) * 2011-08-11 2013-02-14 Tammo Heeren Reducing Damage From A Dielectric Breakdown in Surgical Applications
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
WO2013101631A2 (en) 2011-12-28 2013-07-04 Abbott Laboratories Methods and apparatus to reduce biological carryover using induction heating
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
WO2014025397A1 (en) 2012-08-06 2014-02-13 Shockwave Medical, Inc. Low profile electrodes for an angioplasty shock wave catheter
US9554815B2 (en) 2012-08-08 2017-01-31 Shockwave Medical, Inc. Shockwave valvuloplasty with multiple balloons
NL2009424C2 (en) 2012-09-06 2014-03-10 D O R C Dutch Ophthalmic Res Ct International B V Irrigation/aspiration system, cartridge, pump unit, surgical machine, method for controlling.
US9522012B2 (en) 2012-09-13 2016-12-20 Shockwave Medical, Inc. Shockwave catheter system with energy control
US9333000B2 (en) 2012-09-13 2016-05-10 Shockwave Medical, Inc. Shockwave catheter system with energy control
US9730835B2 (en) 2012-12-19 2017-08-15 Novartis Ag Burst mode vitrectomy system
US9888956B2 (en) 2013-01-22 2018-02-13 Angiodynamics, Inc. Integrated pump and generator device and method of use
BR112015021441A2 (pt) * 2013-03-07 2017-07-18 Arthrocare Corp sistemas e métodos eletrocirúrgicos
USD978375S1 (en) 2013-03-13 2023-02-14 Abbott Laboratories Reagent container
WO2014144627A1 (en) 2013-03-15 2014-09-18 Abbott Laboratories Automated diagnostic analyzers having rear accessible track systems and related methods
US9549850B2 (en) * 2013-04-26 2017-01-24 Novartis Ag Partial venting system for occlusion surge mitigation
US9101764B2 (en) 2013-06-03 2015-08-11 Nanoblate Corp. Methods and devices for stimulating an immune response using nanosecond pulsed electric fields
US20160023020A1 (en) * 2014-07-24 2016-01-28 Strathspey Crown Holdings, LLC System and Method for Inducing a Post-Operative Posterior Vitreous Detachment
US12114911B2 (en) 2014-08-28 2024-10-15 Angiodynamics, Inc. System and method for ablating a tissue site by electroporation with real-time pulse monitoring
EP3193796B1 (en) * 2014-09-18 2021-10-20 Light Matter Interaction Inc. Laser apparatus for treatment of a cataractous lens
US9974689B2 (en) 2014-11-06 2018-05-22 Novartis Ag Dual mode vitrectomy surgical system
WO2016089781A1 (en) 2014-12-01 2016-06-09 Electroblate, Inc. Nanoelectroablation control and vaccination
US10070988B2 (en) * 2014-12-18 2018-09-11 Novartis Ag Devices, systems, and methods for visualization of moving tissue with strobed illumination
CN105310821A (zh) * 2015-05-15 2016-02-10 以诺康医疗科技(苏州)有限公司 一种超声玻切针头及其装置
US10244931B2 (en) 2015-07-13 2019-04-02 Novartis Ag Illuminated ophthalmic infusion line and associated devices, systems, and methods
PL3141204T3 (pl) 2015-09-10 2021-12-06 Erbe Elektromedizin Gmbh Układ do ablacji do obejmującej dużą powierzchnię koagulacji tkanek biologicznych
US11173008B2 (en) 2015-11-01 2021-11-16 Alcon Inc. Illuminated ophthalmic cannula
WO2017087195A1 (en) 2015-11-18 2017-05-26 Shockwave Medical, Inc. Shock wave electrodes
EP3181080A1 (en) * 2015-12-15 2017-06-21 Netvlieschirurg B.V. Microsurgical fine gripping and diathermy forceps and scissors
US10624785B2 (en) 2016-01-30 2020-04-21 Carl Zeiss Meditec Cataract Technology Inc. Devices and methods for ocular surgery
US9827066B2 (en) 2016-02-16 2017-11-28 Novartis Ag Methods and systems for pulsed illumination
US9956053B2 (en) 2016-03-04 2018-05-01 Novartis Ag Cannula with an integrated illumination feature
US10226265B2 (en) 2016-04-25 2019-03-12 Shockwave Medical, Inc. Shock wave device with polarity switching
US20170319851A1 (en) * 2016-05-06 2017-11-09 Pulse Biosciences, Inc. Low-voltage impedance check pulse generator
JP7287888B2 (ja) 2016-06-27 2023-06-06 ギャラリー,インコーポレイテッド ジェネレータ、電極付きのカテーテル、及び肺通路の治療方法
US12403305B2 (en) 2016-06-27 2025-09-02 Galvanize Therapeutics, Inc. Immunostimulation in the treatment of viral infection
EP3777723B1 (en) 2016-10-06 2024-01-17 Shockwave Medical, Inc. Aortic leaflet repair using shock wave applicators
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
US11065352B2 (en) 2016-12-22 2021-07-20 Abbott Laboratories Inductive heating systems and methods of controlling the same to reduce biological carryover
US20220401261A1 (en) * 2017-12-07 2022-12-22 Harry Michael Lambert Ophthalmological surgery microsurgery instruments and methods of use in pars plana vitrectomy for increasing surgical precision and reducing vitreoretinal instrument insertions and removals and related trauma
US20220265469A1 (en) * 2017-09-08 2022-08-25 Harry Michael Lambert Ophthalmological surgery microsurgery instruments and methods of use for increasing surgical precision and reducing vitreoretinal instrument insertions and removals and related trauma
EP4052686B1 (en) 2017-05-04 2025-07-02 Carl Zeiss Meditec Cataract Technology Inc. Devices for ocular surgery
US10996146B2 (en) 2017-06-01 2021-05-04 Becton, Dickinson And Company Devices for dissociating a biological tissue sample and methods of use thereof
US10966737B2 (en) 2017-06-19 2021-04-06 Shockwave Medical, Inc. Device and method for generating forward directed shock waves
CN111031949A (zh) * 2017-08-16 2020-04-17 弗吉尼亚州研究基金会 通过两极纳秒脉冲的干扰进行的靶向远程电刺激
US20190117196A1 (en) * 2017-10-19 2019-04-25 Canon Medical Systems Corporation Ultrasound diagnostic apparatus and ultrasound probe
US10709462B2 (en) 2017-11-17 2020-07-14 Shockwave Medical, Inc. Low profile electrodes for a shock wave catheter
KR102006907B1 (ko) 2018-03-12 2019-10-01 주식회사 씨오아이 안과용 수술 장치
CN112702982B (zh) 2018-06-05 2023-12-19 卡尔蔡司白内障医疗技术公司 眼科显微手术工具、系统和使用方法
AU2019290401B2 (en) 2018-06-21 2025-02-27 Shockwave Medical, Inc. System for treating occlusions in body lumens
JP7434340B2 (ja) 2019-02-01 2024-02-20 カール・ツァイス・メディテック・キャタラクト・テクノロジー・インコーポレイテッド 統合吸引ポンプを有する眼科用切断器具
US20200309760A1 (en) * 2019-03-27 2020-10-01 Alcon Inc. Systems and methods for identifying material during an ophthalmic procedure using ac impedance measurement
JP7652711B2 (ja) 2019-05-17 2025-03-27 カール・ツァイス・メディテック・キャタラクト・テクノロジー・インコーポレイテッド 一体化吸引ポンプを有する眼科用切削器具
CN114206277B (zh) 2019-06-07 2024-06-25 卡尔蔡司白内障医疗技术公司 用于眼科切割工具的多级触发器
ES2968360T3 (es) 2019-09-24 2024-05-09 Shockwave Medical Inc Electrodos de bajo perfil para un catéter de ondas de choque
CN114760940B (zh) 2019-09-24 2025-05-27 冲击波医疗公司 病灶穿过式冲击波导管
US11478261B2 (en) 2019-09-24 2022-10-25 Shockwave Medical, Inc. System for treating thrombus in body lumens
US11992232B2 (en) 2020-10-27 2024-05-28 Shockwave Medical, Inc. System for treating thrombus in body lumens
US12232755B2 (en) * 2020-12-11 2025-02-25 Shockwave Medical, Inc. Lesion crossing shock wave catheter
AU2022238492A1 (en) * 2021-03-19 2023-10-05 Aldevron, Llc Ocular delivery of therapeutic agents
US12023098B2 (en) 2021-10-05 2024-07-02 Shockwave Medical, Inc. Lesion crossing shock wave catheter
US12290268B2 (en) 2023-03-31 2025-05-06 Shockwave Medical, Inc. Shockwave catheters for treating rhinosinusitis
US12035932B1 (en) 2023-04-21 2024-07-16 Shockwave Medical, Inc. Intravascular lithotripsy catheter with slotted emitter bands
US12220141B2 (en) 2023-06-29 2025-02-11 Shockwave Medical, Inc. Catheter system with independently controllable bubble and arc generation
US12496078B2 (en) 2023-08-24 2025-12-16 Shockwave Medical, Inc. Lithotripsy catheters having electrodes formed in metallization layers
US12426904B2 (en) 2023-11-17 2025-09-30 Shockwave Medical, Inc. Intravascular lithotripsy catheter with oscillating impactor
US12594085B2 (en) 2023-11-30 2026-04-07 Shockwave Medical, Inc. Shock wave catheter with shock absorber
US12402899B2 (en) 2023-11-30 2025-09-02 Shockwave Medical, Inc. Systems, devices, and methods for generating shock waves in a forward direction
US12433620B2 (en) 2024-02-23 2025-10-07 Shockwave Medical, Inc. Locus emitter shock wave catheter devices with increased longevity and higher sonic output
US12471939B2 (en) 2024-03-05 2025-11-18 Shockwave Medical, Inc. Shock wave catheter with retractable enclosure
US12178458B1 (en) 2024-05-16 2024-12-31 Shockwave Medical, Inc. Guidewireless shock wave catheters
US12502188B2 (en) 2024-05-31 2025-12-23 Shockwave Medical, Inc. Systems, devices, and methods for shock wave generation utilizing catheters with multi-metal joints
US12453565B1 (en) 2024-11-18 2025-10-28 Shockwave Medical, Inc. Shock wave catheters and methods of use thereof for treating, imaging, and characterizing body lumens

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395258A (en) * 1980-11-03 1983-07-26 Cooper Medical Devices Linear intra-ocular suction device
US4849355A (en) * 1985-01-08 1989-07-18 Wong Tai Kin Method of transferring genes into cells
US4597388A (en) * 1983-12-15 1986-07-01 Trutek Research, Inc. Apparatus for removing cataracts
US5697882A (en) * 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US6277112B1 (en) * 1996-07-16 2001-08-21 Arthrocare Corporation Methods for electrosurgical spine surgery
US7429262B2 (en) * 1992-01-07 2008-09-30 Arthrocare Corporation Apparatus and methods for electrosurgical ablation and resection of target tissue
US6749604B1 (en) * 1993-05-10 2004-06-15 Arthrocare Corporation Electrosurgical instrument with axially-spaced electrodes
EP0651974B1 (en) * 1993-11-10 2000-05-03 Xomed, Inc. Bipolar electrosurgical instrument and method for making the instrument
US6632193B1 (en) * 1995-06-07 2003-10-14 Arthrocare Corporation Systems and methods for electrosurgical tissue treatment
US7507341B2 (en) * 1999-01-13 2009-03-24 Opencel Llc Method of and apparatus for converting biological materials into energy resources
US5914255A (en) * 1996-03-06 1999-06-22 Grae; Joel B. Temperature shock method and apparatus
US5869326A (en) * 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US6352535B1 (en) * 1997-09-25 2002-03-05 Nanoptics, Inc. Method and a device for electro microsurgery in a physiological liquid environment
US6117660A (en) 1997-06-10 2000-09-12 Cytopulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
US6855143B2 (en) * 1997-06-13 2005-02-15 Arthrocare Corporation Electrosurgical systems and methods for recanalization of occluded body lumens
DE19740530A1 (de) 1997-09-15 1999-03-18 Kreco Kreiner Consulting Ges F Vorrichtung zum Entfernen von Augenmaterial
US6479785B1 (en) * 1998-07-09 2002-11-12 Richard J. Fugo Device for plasma incision of mater with a specifically tuned radiofrequencty electromagnetic field generator
US6508816B2 (en) * 1998-03-27 2003-01-21 John H. Shadduck Medical instrument working end creating very high pressure gradients
US5989212A (en) * 1998-06-04 1999-11-23 Alcon Laboratories, Inc. Pumping chamber for a liquefaction handpiece having a countersink electrode
US6787730B2 (en) * 1998-07-09 2004-09-07 Damian Coccio Device for plasma incision of matter with a specifically tuned radiofrequency electromagnetic field generator
US7435247B2 (en) * 1998-08-11 2008-10-14 Arthrocare Corporation Systems and methods for electrosurgical tissue treatment
US6192270B1 (en) * 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue
US6937890B2 (en) * 1998-12-17 2005-08-30 University Of South Florida Nonpenetrating electroporation device
US6135998A (en) * 1999-03-16 2000-10-24 Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for pulsed plasma-mediated electrosurgery in liquid media
AU3576700A (en) 1999-03-24 2000-10-09 Ato B.V. Method for treating products by high voltage pulses
US6678558B1 (en) * 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US7171264B1 (en) * 1999-05-10 2007-01-30 Genetronics, Inc. Intradermal delivery of active agents by needle-free injection and electroporation
US6890332B2 (en) * 1999-05-24 2005-05-10 Csaba Truckai Electrical discharge devices and techniques for medical procedures
US7053063B2 (en) * 1999-07-21 2006-05-30 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes in tissue
US6326177B1 (en) * 1999-08-04 2001-12-04 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Method and apparatus for intracellular electro-manipulation
US7146210B2 (en) * 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US6679879B2 (en) * 2000-08-16 2004-01-20 John H. Shadduck Electrical discharge catheter system for extracting emboli in endovascular interventions
US6795728B2 (en) * 2001-08-17 2004-09-21 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation
WO2002050095A1 (en) * 2000-12-18 2002-06-27 Trustees Of Princeton University Fractionation of macro-molecules using asymmetric pulsed field electrophoresis
US7011790B2 (en) * 2001-05-07 2006-03-14 Regents Of The University Of Minnesota Non-thermal disinfection of biological fluids using non-thermal plasma
US6994706B2 (en) * 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US6730075B2 (en) * 2001-10-12 2004-05-04 The Board Of Trustees Of The Leland Stanford Junior University Surgical probe for use in liquid media
US6783647B2 (en) * 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
US7058269B2 (en) * 2001-10-24 2006-06-06 Institut National D'optique Reconstructed glass for fiber optic applications
AR037038A1 (es) * 2001-10-26 2004-10-20 Baylor College Medicine Una composicion y metodo para alterar la masa corporal magra y las propiedades oseas en un sujeto
JP2005508396A (ja) * 2001-11-02 2005-03-31 イントラディグム、コーポレイション 核酸送達ビヒクルのための治療方法
US20030170898A1 (en) * 2001-12-04 2003-09-11 Gundersen Martin A. Method for intracellular modifications within living cells using pulsed electric fields
US20040219660A1 (en) * 2001-12-14 2004-11-04 Dev Sukhendu B. Electroporation-mediated intravascular delivery
US20070129761A1 (en) * 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US8551069B2 (en) * 2002-04-08 2013-10-08 Medtronic Adrian Luxembourg S.a.r.l. Methods and apparatus for treating contrast nephropathy
US20070135875A1 (en) * 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8131371B2 (en) * 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8145316B2 (en) * 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8145317B2 (en) * 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
DE60322523D1 (de) * 2002-04-16 2008-09-11 Cyto Pulse Sciences Inc Ien mit übersetzenden elektrischen feldern und elektroden-polaritäts-umkehr
US6780178B2 (en) * 2002-05-03 2004-08-24 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for plasma-mediated thermo-electrical ablation
US8043286B2 (en) * 2002-05-03 2011-10-25 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for plasma-mediated thermo-electrical ablation
US7141031B2 (en) * 2002-05-24 2006-11-28 W. G. Holdings, Llc. Cervical collar with end-supported chin strap
FR2841796B1 (fr) * 2002-07-05 2005-03-04 Commissariat Energie Atomique Traitement d'effluents associant separation solide/liquide et champs electriques pulses
US6746613B2 (en) * 2002-11-04 2004-06-08 Steris Inc. Pulsed electric field system for treatment of a fluid medium
GB2395481B (en) 2002-11-19 2006-06-28 C Tech Innovation Ltd Control of biocatalysis reactions
US7316682B2 (en) * 2002-12-17 2008-01-08 Aaron Medical Industries, Inc. Electrosurgical device to generate a plasma stream
US7059269B2 (en) * 2003-02-13 2006-06-13 Steris, Inc. Pulsed electric field system for decontamination of biological agents on a dielectric sheet material
US7736361B2 (en) * 2003-02-14 2010-06-15 The Board Of Trustees Of The Leland Stamford Junior University Electrosurgical system with uniformly enhanced electric field and minimal collateral damage
JP4920407B2 (ja) * 2003-02-14 2012-04-18 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ 周辺組織の破壊が最小限で済む一様な電界を発生する電気外科的システム
JP4006696B2 (ja) * 2003-02-21 2007-11-14 湘南デザイン株式会社 ロストワックス精密鋳造用鋳型の製作方法
US7211083B2 (en) * 2003-03-17 2007-05-01 Minnesota Medical Physics, Llc Apparatus and method for hair removal by electroporation
WO2004112581A2 (en) * 2003-06-18 2004-12-29 The Board Of Trustees Of The Leland Stanford Junior University Electro-adhesive tissue manipulator
US6960978B2 (en) * 2003-07-16 2005-11-01 Hewlett-Packard Development Company, L.P. Fuse structure
JP4810425B2 (ja) * 2003-07-18 2011-11-09 イースタン バージニア メディカル スクール 電気パルスを発生するための装置および該装置を使用する方法
DE20312165U1 (de) 2003-08-01 2004-12-16 Belu Ag Einhausung mit öffen- und schließbaren Seitenwänden und Dachflächen sowie Rolltor hierfür
ES2729378T3 (es) * 2003-12-24 2019-11-04 Univ California Ablación de tejido con electroporación irreversible
US7182762B2 (en) * 2003-12-30 2007-02-27 Smith & Nephew, Inc. Electrosurgical device
US20050209548A1 (en) * 2004-03-19 2005-09-22 Dev Sukhendu B Electroporation-mediated intravascular delivery
JP4899020B2 (ja) * 2004-03-25 2012-03-21 ユニバーシティ・カレッジ・コークーナショナル・ユニバーシティ・オブ・アイルランド,コーク 組織の予防的処置又は治療に用いるための装置
US20050238539A1 (en) * 2004-04-01 2005-10-27 Gal Shafirstein Apparatus for automated fresh tissue sectioning
US7572998B2 (en) * 2004-05-28 2009-08-11 Mohamed Abdel-Aleam H Method and device for creating a micro plasma jet
NL1026422C2 (nl) 2004-06-15 2005-12-19 Univ Eindhoven Tech Inrichting voor het creeren van een lokaal koud plasma ter plaatse van een object.
RU42752U1 (ru) * 2004-08-12 2004-12-20 Жильцов Сергей Геннадьевич Устройство для ирригации передней камеры глаза при хирургическом лечении катаракты
AU2005289828A1 (en) * 2004-09-24 2006-04-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for the non-thermal, electrically-induced closure of blood vessels
US8101169B2 (en) * 2005-02-23 2012-01-24 The Board Of Trustees Of The Leland Stanford Junior University Ocular gene therapy using avalanche-mediated transfection
WO2006124639A1 (en) * 2005-05-11 2006-11-23 Corium International, Inc. Permeabilization of biological membranes
US20080039901A1 (en) * 2005-06-03 2008-02-14 Kronberg James W Methods for modulating chondrocyte proliferation using pulsing electric fields
US20060293731A1 (en) * 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating tumors using electroporation
US20060293730A1 (en) * 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating restenosis sites using electroporation
US8114070B2 (en) * 2005-06-24 2012-02-14 Angiodynamics, Inc. Methods and systems for treating BPH using electroporation
US20060293725A1 (en) * 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating fatty tissue sites using electroporation
US7608839B2 (en) * 2005-08-05 2009-10-27 Mcgill University Plasma source and applications thereof
US20070265215A1 (en) * 2006-05-11 2007-11-15 Iversen Patrick L Antisense restenosis composition and method
WO2008021321A2 (en) * 2006-08-17 2008-02-21 Rjf Holdings Iv, Inc Method and apparatus for plasma incision of cardiovascular tissue
US7931811B2 (en) * 2006-10-27 2011-04-26 Regents Of The University Of Minnesota Dielectric barrier reactor having concentrated electric field
GB2452103B (en) * 2007-01-05 2011-08-31 Arthrocare Corp Electrosurgical system with suction control apparatus and system
US7655004B2 (en) * 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US8139339B2 (en) * 2007-03-16 2012-03-20 Old Dominion University Research Foundation Modulation of neuromuscular functions with ultrashort electrical pulses
WO2008118393A1 (en) * 2007-03-23 2008-10-02 University Of Southern California Compact subnanosecond high voltage pulse generation system for cell electro-manipulation
WO2008119749A1 (en) * 2007-03-29 2008-10-09 Novozymes A/S Process for treating vegetable material with an enzyme
US20110118734A1 (en) * 2009-11-16 2011-05-19 Alcon Research, Ltd. Capsularhexis device using pulsed electric fields

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BRPI0620895A2 (pt) 2011-11-29
IL192344A0 (en) 2009-02-11
EP1968470A2 (en) 2008-09-17
AR058905A1 (es) 2008-03-05
IL192344A (en) 2013-01-31
BRPI0620895B1 (pt) 2018-05-22
US20100331911A1 (en) 2010-12-30
CA2632970C (en) 2012-01-24
JP2009522047A (ja) 2009-06-11
ES2342790T3 (es) 2010-07-14
TW200730157A (en) 2007-08-16
ATE466537T1 (de) 2010-05-15
CN101389280A (zh) 2009-03-18
MX2008008598A (es) 2008-09-26
RU2008131943A (ru) 2010-02-10
WO2007081474A3 (en) 2007-09-07
KR101296325B1 (ko) 2013-08-14
WO2007081474A2 (en) 2007-07-19
KR20080092400A (ko) 2008-10-15
CA2632970A1 (en) 2007-07-19
CN101389280B (zh) 2011-02-16
DE602006014206D1 (de) 2010-06-17
EP1968470B1 (en) 2010-05-05
RU2419394C2 (ru) 2011-05-27
TWI360410B (en) 2012-03-21
US7824870B2 (en) 2010-11-02
AU2006335194B2 (en) 2011-10-27
US20070156129A1 (en) 2007-07-05
JP5032500B2 (ja) 2012-09-26
AU2006335194A1 (en) 2007-07-19

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