CL2008000066A1 - Compuestos derivados de (5-hidroxi-3-oxo-2,3-dihidropiridazina-4-carbonil)glicina, inhibidores de hif prolil hidroxilasas; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la anem - Google Patents

Compuestos derivados de (5-hidroxi-3-oxo-2,3-dihidropiridazina-4-carbonil)glicina, inhibidores de hif prolil hidroxilasas; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la anem

Info

Publication number
CL2008000066A1
CL2008000066A1 CL200800066A CL2008000066A CL2008000066A1 CL 2008000066 A1 CL2008000066 A1 CL 2008000066A1 CL 200800066 A CL200800066 A CL 200800066A CL 2008000066 A CL2008000066 A CL 2008000066A CL 2008000066 A1 CL2008000066 A1 CL 2008000066A1
Authority
CL
Chile
Prior art keywords
compounds
hifroxylase
dihydropiridazine
anem
oxo
Prior art date
Application number
CL200800066A
Other languages
English (en)
Inventor
Kevin J Duffy
Antony N Shaw
William Henry Miller
Andrea K Myers
Michael N Zimmerman
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39636631&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008000066(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of CL2008000066A1 publication Critical patent/CL2008000066A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CL200800066A 2007-01-12 2008-01-10 Compuestos derivados de (5-hidroxi-3-oxo-2,3-dihidropiridazina-4-carbonil)glicina, inhibidores de hif prolil hidroxilasas; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la anem CL2008000066A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88471007P 2007-01-12 2007-01-12

Publications (1)

Publication Number Publication Date
CL2008000066A1 true CL2008000066A1 (es) 2008-08-01

Family

ID=39636631

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200800066A CL2008000066A1 (es) 2007-01-12 2008-01-10 Compuestos derivados de (5-hidroxi-3-oxo-2,3-dihidropiridazina-4-carbonil)glicina, inhibidores de hif prolil hidroxilasas; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la anem

Country Status (20)

Country Link
US (2) US7608621B2 (es)
EP (2) EP2124565B1 (es)
JP (1) JP5313925B2 (es)
KR (1) KR101458655B1 (es)
CN (1) CN101626685B (es)
AR (1) AR064878A1 (es)
AU (1) AU2008206441B2 (es)
BR (1) BRPI0806566A2 (es)
CA (1) CA2675252C (es)
CL (1) CL2008000066A1 (es)
DK (1) DK2124565T3 (es)
EA (1) EA017112B1 (es)
ES (2) ES2528745T3 (es)
HR (1) HRP20150119T1 (es)
MX (1) MX2009007548A (es)
PL (1) PL2124565T3 (es)
PT (1) PT2124565E (es)
SI (1) SI2124565T1 (es)
TW (1) TW200845991A (es)
WO (1) WO2008089052A2 (es)

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ES2444574T3 (es) * 2006-09-19 2014-02-25 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de la indolamina 2,3-dioxigenasa
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EP2294066B9 (en) 2008-04-28 2015-03-11 Janssen Pharmaceutica, N.V. Benzoimidazoles as prolyl hydroxylase inhibitors
PL2315756T3 (pl) 2008-07-08 2015-02-27 Incyte Holdings Corp 1,2,5-oksadiazole jako inhibitory 2,3-dioksygenazy indoloaminy
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WO2010055884A1 (ja) * 2008-11-13 2010-05-20 日本農薬株式会社 ピラジン誘導体類の製造方法及びその中間体類
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WO2011048611A1 (en) * 2009-10-07 2011-04-28 Torrent Pharmaceuticals Limited Novel fused pyridazine derivatives
KR101665749B1 (ko) 2009-10-21 2016-10-12 다이이찌 산쿄 가부시키가이샤 5-하이드록시피리미딘-4-카르복사미드 유도체
EP3698794A1 (en) 2009-11-06 2020-08-26 Aerpio Therapeutics, Inc. Compositions and methods for treating colitis
WO2011115687A2 (en) * 2010-03-19 2011-09-22 Northwestern University Alkylated sp-b peptoid compounds and related lung surfactant compositions
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EP2717870B1 (en) 2011-06-06 2017-09-27 Akebia Therapeutics Inc. Composition for stabilizing hypoxia inducible factor-2 alpha useful for treating cancer
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US9273034B2 (en) 2011-10-25 2016-03-01 Janssen Pharmaceutica Nv Meglumine salt formulations of 1-(5,6-dichloro-1H-benzo[D]imidazol-2-yl)-1H-pyrazole-4-carboxylic acid
MX360858B (es) 2012-07-30 2018-11-20 Taisho Pharmaceutical Co Ltd Compuesto heterocíclico que contiene nitrógeno parcialmente saturado.
SG10201910773VA (en) 2013-06-13 2020-01-30 Akebia Therapeutics Inc Compositions and methods for treating anemia
DK3066085T3 (da) 2013-11-08 2020-06-02 Incyte Holdings Corp Fremgangsmåde til syntesen af en indolamin-2,3-dioxygenaseinhibitor
AR099354A1 (es) 2013-11-15 2016-07-20 Akebia Therapeutics Inc Formas sólidas de ácido {[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino}acético, composiciones, y sus usos
JP6506390B2 (ja) 2014-09-02 2019-04-24 サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． キノリノン系化合物及びその薬物への使用
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Also Published As

Publication number Publication date
SI2124565T1 (sl) 2015-04-30
EP2124565A4 (en) 2011-06-29
MX2009007548A (es) 2009-07-22
EA017112B1 (ru) 2012-09-28
CA2675252A1 (en) 2008-07-24
TW200845991A (en) 2008-12-01
EA200970680A1 (ru) 2010-02-26
WO2008089052A3 (en) 2008-09-18
CN101626685B (zh) 2013-03-13
AR064878A1 (es) 2009-04-29
AU2008206441A1 (en) 2008-07-24
CN101626685A (zh) 2010-01-13
US7608621B2 (en) 2009-10-27
ES2614355T3 (es) 2017-05-30
BRPI0806566A2 (pt) 2014-05-06
WO2008089052A2 (en) 2008-07-24
US20080214549A1 (en) 2008-09-04
ES2528745T3 (es) 2015-02-12
EP2889289A1 (en) 2015-07-01
KR101458655B1 (ko) 2014-11-05
CA2675252C (en) 2015-05-26
PL2124565T3 (pl) 2015-05-29
AU2008206441B2 (en) 2014-06-19
EP2124565B1 (en) 2015-01-07
USRE44613E1 (en) 2013-11-26
EP2889289B1 (en) 2016-12-21
HRP20150119T1 (hr) 2015-05-08
PT2124565E (pt) 2015-03-26
KR20090101376A (ko) 2009-09-25
DK2124565T3 (en) 2015-02-09
EP2124565A2 (en) 2009-12-02
JP5313925B2 (ja) 2013-10-09
JP2010515756A (ja) 2010-05-13

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