BRPI0700133A - composição farmacêutica compreendendo tramadol e cetoprofeno em combinação - Google Patents

composição farmacêutica compreendendo tramadol e cetoprofeno em combinação

Info

Publication number
BRPI0700133A
BRPI0700133A BRPI0700133-9A BRPI0700133A BRPI0700133A BR PI0700133 A BRPI0700133 A BR PI0700133A BR PI0700133 A BRPI0700133 A BR PI0700133A BR PI0700133 A BRPI0700133 A BR PI0700133A
Authority
BR
Brazil
Prior art keywords
combination
tramadol
pharmaceutical composition
ketoprofen
active ingredients
Prior art date
Application number
BRPI0700133-9A
Other languages
English (en)
Inventor
Henry Jun Suzuki
Dante Alario Jr
Original Assignee
Incrementha P D & I Pesquisa D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39674529&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0700133(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incrementha P D & I Pesquisa D filed Critical Incrementha P D & I Pesquisa D
Priority to BRPI0700133-9A priority Critical patent/BRPI0700133A/pt
Priority to US12/525,035 priority patent/US8715726B2/en
Priority to EP08700474.3A priority patent/EP2117519B1/en
Priority to PCT/BR2008/000024 priority patent/WO2008092219A2/en
Priority to ES08700474.3T priority patent/ES2525668T3/es
Priority to JP2009547495A priority patent/JP5441117B2/ja
Priority to CL200800227A priority patent/CL2008000227A1/es
Priority to PT87004743T priority patent/PT2117519E/pt
Priority to ARP080100347A priority patent/AR065068A1/es
Priority to MX2009008108A priority patent/MX2009008108A/es
Priority to PE2008000200A priority patent/PE20081637A1/es
Publication of BRPI0700133A publication Critical patent/BRPI0700133A/pt
Priority to CO09079003A priority patent/CO6210807A2/es
Priority to EC2009009596A priority patent/ECSP099596A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSIçãO FARMACêUTICA COMPREENDENDO TRAMADOL E CETOPROFENO EM COMBINAçãO. A presente invenção se refere a uma composição farmacêutica compreendendo uma combinação de princípios ativos. Mais especificamente: uma composição farmacêutica estável compreendendo uma combinação de tramadol com cetoprofeno. Adicionalmente, uma combinação na forma sólida em que os princípios ativos são veiculados em formas e/ou produtos farmacêuticos que evitem o contato entre eles. Complementarmente, a presente invenção também se refere ao uso de cetoprofeno e de tramadol, em combinação, na preparação de um medicamento oral útil no alívio da dor, bem como a um método de alívio da dor com uma composição farmacêutica oral compreendendo a combinação de tramadol e cetoprofeno.
BRPI0700133-9A 2007-01-29 2007-01-29 composição farmacêutica compreendendo tramadol e cetoprofeno em combinação BRPI0700133A (pt)

Priority Applications (13)

Application Number Priority Date Filing Date Title
BRPI0700133-9A BRPI0700133A (pt) 2007-01-29 2007-01-29 composição farmacêutica compreendendo tramadol e cetoprofeno em combinação
PE2008000200A PE20081637A1 (es) 2007-01-29 2008-01-28 Composicion farmaceutica que contiene tramadol y ketoprofeno en asociacion
CL200800227A CL2008000227A1 (es) 2007-01-29 2008-01-28 Composicion farmaceutica que comprende una combinacion de uso oral de tramadol y ketoprofeno; y uso en el tratamiento del dolor.
EP08700474.3A EP2117519B1 (en) 2007-01-29 2008-01-28 Pharmaceutical composition comprising tramadol and ketoprofen in association
PCT/BR2008/000024 WO2008092219A2 (en) 2007-01-29 2008-01-28 Pharmaceutical composition comprising tramadol and ketoprofen
ES08700474.3T ES2525668T3 (es) 2007-01-29 2008-01-28 Composición farmacéutica que comprende tramadol y quetoprofeno en asociación
JP2009547495A JP5441117B2 (ja) 2007-01-29 2008-01-28 トラマドールおよびケトプロフェンを組合せて含む薬学的組成物
US12/525,035 US8715726B2 (en) 2007-01-29 2008-01-28 Pharmaceutical composition comprising tramadol and ketoprofen in association
PT87004743T PT2117519E (pt) 2007-01-29 2008-01-28 Composição farmaceutica compreendendo tramadol e cetoprofeno
ARP080100347A AR065068A1 (es) 2007-01-29 2008-01-28 Composicion farmaceutica que comprende tramadol y ketoprofeno en asociacion
MX2009008108A MX2009008108A (es) 2007-01-29 2008-01-28 Composicion farmaceutica que contiene una combinacion de tramadol y ketoprofeno.
CO09079003A CO6210807A2 (es) 2007-01-29 2009-07-29 Composicion farmacetica que farmaceutica que contiene una combinacion de tramadol y ketoprofeno
EC2009009596A ECSP099596A (es) 2007-01-29 2009-08-24 Composición farmacéutica que contiene una combinación de tramadol y ketoprofeno

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0700133-9A BRPI0700133A (pt) 2007-01-29 2007-01-29 composição farmacêutica compreendendo tramadol e cetoprofeno em combinação

Publications (1)

Publication Number Publication Date
BRPI0700133A true BRPI0700133A (pt) 2008-09-16

Family

ID=39674529

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0700133-9A BRPI0700133A (pt) 2007-01-29 2007-01-29 composição farmacêutica compreendendo tramadol e cetoprofeno em combinação

Country Status (13)

Country Link
US (1) US8715726B2 (pt)
EP (1) EP2117519B1 (pt)
JP (1) JP5441117B2 (pt)
AR (1) AR065068A1 (pt)
BR (1) BRPI0700133A (pt)
CL (1) CL2008000227A1 (pt)
CO (1) CO6210807A2 (pt)
EC (1) ECSP099596A (pt)
ES (1) ES2525668T3 (pt)
MX (1) MX2009008108A (pt)
PE (1) PE20081637A1 (pt)
PT (1) PT2117519E (pt)
WO (1) WO2008092219A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2353541B1 (es) 2009-07-30 2011-09-20 Farmalider, S.A. Combinacion de ingredientes activos cosmeticos y composicion cosmetica obtenida a partir de la misma, y su utilizacion.
ES2432222B1 (es) 2012-04-30 2014-06-10 Farmalider S.A. Composición farmacéutica inyectable de dexketoprofeno y tramadol
ITMI20130210A1 (it) * 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
WO2019122982A1 (en) 2017-12-21 2019-06-27 Grünenthal GmbH Pharmaceutical combination in a bilayer tablet form comprising ketorolac tromethamine and tramadol hydrochloride, and its use in pain treatment
WO2019130049A1 (en) 2017-12-29 2019-07-04 Grünenthal GmbH Pharmaceutical combination comprising extended-release tramadol hydrochloride and immediate-release etoricoxib, and its use for the treatment of pain
EP4188337A1 (en) 2020-07-31 2023-06-07 KRKA, d.d., Novo mesto Formulation containing dexketoprofen and tramadol and method for making the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5914129A (en) * 1996-07-23 1999-06-22 Mauskop; Alexander Analgesic composition for treatment of migraine headaches
JP5502254B2 (ja) * 2001-01-31 2014-05-28 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 少なくとも２種類の異なる被覆ペレット形から成る多粒子剤形
ES2380827T3 (es) * 2002-12-26 2012-05-18 Pozen, Inc. Formas de dosificación con múltiples capas que contienen naproxeno y triptanes
FR2855756B1 (fr) 2003-06-06 2005-08-26 Ethypharm Sa Comprime orodispersible multicouche
KR101125268B1 (ko) * 2003-06-06 2012-04-23 에띠팜 구강 분산성 다중층 정제
WO2005034859A2 (en) * 2003-10-03 2005-04-21 Elite Laboratories Inc. Extended release formulations of opioids and method of use thereof
BRPI0612802A2 (pt) * 2005-07-07 2010-11-30 Farnam Co Inc composições farmacêuticas de liberação sustentada para medicamentos extremamente hidrossolúveis
US20070207200A1 (en) * 2006-03-06 2007-09-06 Pozen Inc. Dosage forms for administering combinations of drugs

Also Published As

Publication number Publication date
JP2010516789A (ja) 2010-05-20
EP2117519A2 (en) 2009-11-18
AR065068A1 (es) 2009-05-13
PE20081637A1 (es) 2008-11-22
JP5441117B2 (ja) 2014-03-12
ES2525668T3 (es) 2014-12-29
US8715726B2 (en) 2014-05-06
MX2009008108A (es) 2009-12-14
PT2117519E (pt) 2014-12-18
ECSP099596A (es) 2009-09-29
WO2008092219A3 (en) 2008-09-25
US20100062060A1 (en) 2010-03-11
CO6210807A2 (es) 2010-10-20
WO2008092219A2 (en) 2008-08-07
EP2117519B1 (en) 2014-09-10
CL2008000227A1 (es) 2008-08-08
EP2117519A4 (en) 2011-10-12

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B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
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Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

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Owner name: BIOLAB SANUS FARMACEUTICA LTDA. (BR/SP)

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