BRPI0712195A2 - composição farmacéutica, e, usos da composição e de um inibidor de reabsorção da serotonina ou um sal farmaceuticamente aceitável do mesmo e de 5-hidroxitriptofano - Google Patents

composição farmacéutica, e, usos da composição e de um inibidor de reabsorção da serotonina ou um sal farmaceuticamente aceitável do mesmo e de 5-hidroxitriptofano Download PDF

Info

Publication number: BRPI0712195A2
Authority: BR; Brazil
Prior art keywords: hydroxytryptophan; administered; amount; pharmaceutically acceptable; acceptable salt
Prior art date: 2007-05-11

Application number

BRPI0712195-4A

Other languages

English (en)

Portuguese (pt)

Inventor

Connie Sanchez Morillo

Toni D Wolinsky

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-11

Filing date

2007-05-11

Publication date

2012-01-10

2007-05-11 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2012-01-10 Publication of BRPI0712195A2 publication Critical patent/BRPI0712195A2/pt

Links

229940000681 5-hydroxytryptophan Drugs 0.000 title claims abstract description 155
LDCYZAJDBXYCGN-UHFFFAOYSA-N oxitriptan Natural products C1=C(O)C=C2C(CC(N)C(O)=O)=CNC2=C1 LDCYZAJDBXYCGN-UHFFFAOYSA-N 0.000 title claims abstract description 154
LDCYZAJDBXYCGN-VIFPVBQESA-N 5-hydroxy-L-tryptophan Chemical compound C1=C(O)C=C2C(C[C@H](N)C(O)=O)=CNC2=C1 LDCYZAJDBXYCGN-VIFPVBQESA-N 0.000 title claims abstract description 153
239000003772 serotonin uptake inhibitor Substances 0.000 title claims abstract description 110
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150000003839 salts Chemical class 0.000 title claims abstract description 33
QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims abstract description 80
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WSEQXVZVJXJVFP-FQEVSTJZSA-N escitalopram Chemical compound C1([C@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-FQEVSTJZSA-N 0.000 claims description 70
AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 claims description 48
AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 claims description 46
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
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- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0712195-4A 2007-05-11 2007-05-11 composição farmacéutica, e, usos da composição e de um inibidor de reabsorção da serotonina ou um sal farmaceuticamente aceitável do mesmo e de 5-hidroxitriptofano BRPI0712195A2 (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2007/011362 WO2008140448A1 (fr)	2007-05-11	2007-05-11	Polythérapie à base de 5-htp

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BRPI0712195A2 true BRPI0712195A2 (pt)	2012-01-10

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Country Status (11)

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EP (1)	EP2155181A4 (fr)
JP (1)	JP2010526804A (fr)
KR (1)	KR20100014081A (fr)
CN (1)	CN101472575A (fr)
AU (1)	AU2007353453A1 (fr)
BR (1)	BRPI0712195A2 (fr)
CA (1)	CA2655846A1 (fr)
EA (1)	EA200870554A1 (fr)
IL (1)	IL196041A0 (fr)
NO (1)	NO20085278L (fr)
WO (1)	WO2008140448A1 (fr)

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US11464756B1 (en)	2017-05-19	2022-10-11	Jerry Darm	Mecuna pruriens, L-DOPA and 5-HTP based dietary supplements, pharmaceutical formulations and uses thereof

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US6579899B1 (en) *	1998-07-16	2003-06-17	Massachusetts Institute Of Technology	Composition for treatment of stress

2007
- 2007-05-11 CN CNA2007800229678A patent/CN101472575A/zh active Pending
- 2007-05-11 BR BRPI0712195-4A patent/BRPI0712195A2/pt not_active IP Right Cessation
- 2007-05-11 EP EP07776982A patent/EP2155181A4/fr not_active Withdrawn
- 2007-05-11 EA EA200870554A patent/EA200870554A1/ru unknown
- 2007-05-11 WO PCT/US2007/011362 patent/WO2008140448A1/fr not_active Ceased
- 2007-05-11 AU AU2007353453A patent/AU2007353453A1/en not_active Abandoned
- 2007-05-11 KR KR1020087030898A patent/KR20100014081A/ko not_active Withdrawn
- 2007-05-11 CA CA002655846A patent/CA2655846A1/fr not_active Abandoned
- 2007-05-11 JP JP2010507368A patent/JP2010526804A/ja active Pending
2008
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Publication number	Publication date
JP2010526804A (ja)	2010-08-05
AU2007353453A1 (en)	2008-11-20
CA2655846A1 (fr)	2008-11-20
EP2155181A1 (fr)	2010-02-24
KR20100014081A (ko)	2010-02-10
EA200870554A1 (ru)	2009-04-28
NO20085278L (no)	2009-02-12
WO2008140448A1 (fr)	2008-11-20
CN101472575A (zh)	2009-07-01
EP2155181A4 (fr)	2012-02-29
IL196041A0 (en)	2009-09-01

Legal Events

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2012-06-05	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A E 5A ANUIDADES.
2012-11-13	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 4A E 5A ANUIDADES.

Publication	Publication Date	Title
US20120258984A1 (en)	2012-10-11	5-htp combination therapy
US20100267772A1 (en)	2010-10-21	Combination of a Serotonin Reuptake Inhibitor and Agomelatine
WO2001041766A1 (fr)	2001-06-14	Combinaison d'inhibiteur de recaptage de serotonine et d'irindalone
TW200843763A (en)	2008-11-16	5-HTP combination therapy
US20020107244A1 (en)	2002-08-08	Combination treatment for depression
EP2145620A2 (fr)	2010-01-20	Gaboxadole pour le traitement de la dépression et d'autres troubles affectifs
AU2003240434A1 (en)	2004-01-06	Combination therapy wherein a serotinin reuptake inhibitor is used
WO2009042632A2 (fr)	2009-04-02	Traitement combiné associé à des composés à double action à base de sérotonine
BRPI0712195A2 (pt)	2012-01-10	composição farmacéutica, e, usos da composição e de um inibidor de reabsorção da serotonina ou um sal farmaceuticamente aceitável do mesmo e de 5-hidroxitriptofano
CA2537747A1 (fr)	2005-03-17	Combinaison d'un inhibiteur de recaptage de serotonine et de loxapine
US20070042014A1 (en)	2007-02-22	Combination of a serotonin reuptake inhibitor and loxapine
WO2005056056A2 (fr)	2005-06-23	Combinaison d'un inhibiteur de reabsorption de la serotonine et d'un antagoniste du recepteur de l'histamine 3, agoniste inverse ou partiel
US20070066601A1 (en)	2007-03-22	Combination of a serotonin reuptake inhibitor and a histamine 3 receptor antagonist, inverse agonist or partial agonist
HK1134241A (en)	2010-04-23	5-htp combination therapy
MX2008016138A (es)	2009-05-13	Terapia de combinacion de 5-htp
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US20080167290A1 (en)	2008-07-10	Combination of a Serotonin Reuptake Inhibitor and Amoxapine
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