BRPI0713814A2 - saiais monovalente e bivalente de Ácido glutamÍnico-l-n- (5-hidroxicotinoila) exibindo aÇço psicotràpica (antidepressiva e anxiolÍtica), cÉrebroprotetora e heroprotetora, neuroprotetora - Google Patents
saiais monovalente e bivalente de Ácido glutamÍnico-l-n- (5-hidroxicotinoila) exibindo aÇço psicotràpica (antidepressiva e anxiolÍtica), cÉrebroprotetora e heroprotetora, neuroprotetoraInfo
- Publication number
- BRPI0713814A2 BRPI0713814A2 BRPI0713814-8A2A BRPI0713814A BRPI0713814A2 BR PI0713814 A2 BRPI0713814 A2 BR PI0713814A2 BR PI0713814 A BRPI0713814 A BR PI0713814A BR PI0713814 A2 BRPI0713814 A2 BR PI0713814A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxycottinoyl
- heroprotective
- cerebroprotective
- anxiolytic
- antidepressant
- Prior art date
Links
- 230000001430 anti-depressive effect Effects 0.000 title 1
- 239000000935 antidepressant agent Substances 0.000 title 1
- 229940005513 antidepressants Drugs 0.000 title 1
- 239000002249 anxiolytic agent Substances 0.000 title 1
- 230000000949 anxiolytic effect Effects 0.000 title 1
- 230000001966 cerebroprotective effect Effects 0.000 title 1
- 230000001747 exhibiting effect Effects 0.000 title 1
- 230000000324 neuroprotective effect Effects 0.000 title 1
- 230000000506 psychotropic effect Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006127564/04A RU2314293C1 (ru) | 2006-07-31 | 2006-07-31 | Одно- и двухвалентные соли n-(5-гидроксиникотиноил)-l-глутаминовой кислоты, обладающие психотропным (антидепрессивным и анксиолитическим), нейропротекторным, геропротекторным и противоинсультным действием |
| PCT/RU2007/000304 WO2008018815A1 (fr) | 2006-07-31 | 2007-06-06 | Sels monovalents ou divalents d'acide n-(5-hydroxynicotinoyl)-l-glutaminique présentant un effet psychotrope (antidépresseur et anxiolytique), neuroprotecteur, géroprotecteur et cérébroprotecteur |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0713814A2 true BRPI0713814A2 (pt) | 2013-09-17 |
| BRPI0713814A8 BRPI0713814A8 (pt) | 2018-01-09 |
Family
ID=39020154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0713814A BRPI0713814A8 (pt) | 2006-07-31 | 2007-06-06 | saiais monovalente e bivalente de ácido glutamínico-l-n- (5-hidroxicotinoila) exibindo ação psicotrópica (antidepressiva e anxiolítica), cérebroprotetora e heroprotetora, neuroprotetora |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8030493B2 (pt) |
| EP (1) | EP2050737A4 (pt) |
| JP (1) | JP2009545589A (pt) |
| KR (1) | KR101439561B1 (pt) |
| CN (1) | CN101500998B (pt) |
| AU (1) | AU2007282178A1 (pt) |
| BR (1) | BRPI0713814A8 (pt) |
| CA (1) | CA2658589A1 (pt) |
| EA (1) | EA014855B1 (pt) |
| MX (1) | MX2009000400A (pt) |
| NZ (1) | NZ574637A (pt) |
| RU (1) | RU2314293C1 (pt) |
| UA (1) | UA93269C2 (pt) |
| WO (1) | WO2008018815A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2398761C2 (ru) * | 2008-06-16 | 2010-09-10 | Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) | Средства, обладающие анксиолитическими свойствами |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1368314A1 (ru) * | 1984-02-22 | 1988-01-23 | Научно-исследовательский институт фармакологии АМН СССР | @ -Никотиноиламинокислоты, обладающие противогипоксической и антиамнестической активностью |
| RU2068408C1 (ru) * | 1992-06-24 | 1996-10-27 | Всесоюзный научный центр по безопасности биологически активных веществ (ВНЦ БАВ) | СПОСОБ ПОЛУЧЕНИЯ N-АЦЕТИЛ- α -ГЛУТАМИНОВОЙ КИСЛОТЫ |
| RU94038232A (ru) | 1994-10-10 | 1996-08-27 | Научно-исследовательский институт фармакологии Томского научного центра РАМН | Средство, улучшающее мозговое кровообращение |
-
2006
- 2006-07-31 RU RU2006127564/04A patent/RU2314293C1/ru active IP Right Revival
-
2007
- 2007-06-06 JP JP2009522734A patent/JP2009545589A/ja active Pending
- 2007-06-06 WO PCT/RU2007/000304 patent/WO2008018815A1/ru not_active Ceased
- 2007-06-06 CN CN2007800277101A patent/CN101500998B/zh not_active Expired - Fee Related
- 2007-06-06 MX MX2009000400A patent/MX2009000400A/es active IP Right Grant
- 2007-06-06 NZ NZ574637A patent/NZ574637A/en not_active IP Right Cessation
- 2007-06-06 EA EA200900274A patent/EA014855B1/ru not_active IP Right Cessation
- 2007-06-06 AU AU2007282178A patent/AU2007282178A1/en not_active Abandoned
- 2007-06-06 EP EP07794038A patent/EP2050737A4/en not_active Withdrawn
- 2007-06-06 CA CA002658589A patent/CA2658589A1/en not_active Abandoned
- 2007-06-06 BR BRPI0713814A patent/BRPI0713814A8/pt not_active Application Discontinuation
- 2007-06-06 UA UAA200901767A patent/UA93269C2/ru unknown
- 2007-06-06 KR KR1020087031699A patent/KR101439561B1/ko not_active Expired - Fee Related
- 2007-06-06 US US12/309,543 patent/US8030493B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EA200900274A1 (ru) | 2009-06-30 |
| CN101500998B (zh) | 2011-06-01 |
| KR101439561B1 (ko) | 2014-09-11 |
| US20090240059A1 (en) | 2009-09-24 |
| CN101500998A (zh) | 2009-08-05 |
| EA014855B1 (ru) | 2011-02-28 |
| UA93269C2 (en) | 2011-01-25 |
| EP2050737A4 (en) | 2011-05-04 |
| KR20090037996A (ko) | 2009-04-17 |
| WO2008018815A1 (fr) | 2008-02-14 |
| US8030493B2 (en) | 2011-10-04 |
| RU2314293C1 (ru) | 2008-01-10 |
| CA2658589A1 (en) | 2008-02-14 |
| NZ574637A (en) | 2010-10-29 |
| MX2009000400A (es) | 2009-03-02 |
| EP2050737A1 (en) | 2009-04-22 |
| JP2009545589A (ja) | 2009-12-24 |
| BRPI0713814A8 (pt) | 2018-01-09 |
| AU2007282178A1 (en) | 2008-02-14 |
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| BRPI0713814A8 (pt) | saiais monovalente e bivalente de ácido glutamínico-l-n- (5-hidroxicotinoila) exibindo ação psicotrópica (antidepressiva e anxiolítica), cérebroprotetora e heroprotetora, neuroprotetora |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |