BRPI0716397A2 - mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero. - Google Patents

mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero.

Info

Publication number
BRPI0716397A2
BRPI0716397A2 BRPI0716397-5A2A BRPI0716397A BRPI0716397A2 BR PI0716397 A2 BRPI0716397 A2 BR PI0716397A2 BR PI0716397 A BRPI0716397 A BR PI0716397A BR PI0716397 A2 BRPI0716397 A2 BR PI0716397A2
Authority
BR
Brazil
Prior art keywords
promote osteogenesis
methods
mammalian cell
identify agents
osteogenesis
Prior art date
Application number
BRPI0716397-5A2A
Other languages
English (en)
Inventor
Yuanxiang Zhao
Sheng Ding
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of BRPI0716397A2 publication Critical patent/BRPI0716397A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0716397-5A2A 2006-08-11 2007-08-10 mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero. BRPI0716397A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82218406P 2006-08-11 2006-08-11
US11/836,512 US7601501B2 (en) 2006-08-11 2007-08-09 Controlling osteogenesis by inhibition of osteogenic suppressors
PCT/US2007/017797 WO2008019159A2 (en) 2006-08-11 2007-08-10 Controlling osteogenesis by inhibition of osteogenic suppressors

Publications (1)

Publication Number Publication Date
BRPI0716397A2 true BRPI0716397A2 (pt) 2013-09-17

Family

ID=39033527

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0716397-5A2A BRPI0716397A2 (pt) 2006-08-11 2007-08-10 mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero.

Country Status (11)

Country Link
US (2) US7601501B2 (pt)
EP (1) EP2049158A4 (pt)
JP (1) JP2010500567A (pt)
KR (1) KR20090047508A (pt)
AU (1) AU2007281931A1 (pt)
BR (1) BRPI0716397A2 (pt)
CA (1) CA2659437A1 (pt)
IL (1) IL196760A0 (pt)
MX (1) MX2009001372A (pt)
RU (1) RU2009108662A (pt)
WO (1) WO2008019159A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009020601A2 (en) 2007-08-03 2009-02-12 Cornell University Atf4 inhibitors and their use for neural protection, repair, regeneration, and plasticity
PT2453921E (pt) * 2009-07-14 2015-09-25 Novartis Ag Diferenciação de células estaminais mesenquimais
EP2380595A1 (en) 2010-04-19 2011-10-26 Nlife Therapeutics S.L. Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types
JP2014526517A (ja) * 2011-09-14 2014-10-06 ノースウェスタン ユニバーシティ 血液脳関門を通過することができるナノ抱合体
WO2017053963A1 (en) 2015-09-25 2017-03-30 Cedars-Sinal Medical Center A method effective to modulate expression of t-box protein 4 (tbx4) for reducing progression of lung fibrosis after a lung injury
WO2019070908A1 (en) 2017-10-03 2019-04-11 Cedars-Sinai Medical Center METHODS OF TARGETING THE PD1 PATHWAY OF THE IMMUNE CONTROL POINT FOR THE TREATMENT OF PULMONARY FIBROSIS
CN113631709A (zh) * 2018-12-20 2021-11-09 普拉克西斯精密药物股份有限公司 用于治疗kcnt1相关病症的组合物和方法
PH12021552220A1 (en) * 2019-03-15 2022-05-30 Ionis Pharmaceuticals Inc Compounds and methods for reducing kcnt1 expression
CA3140917A1 (en) * 2019-05-24 2020-12-03 Empirico Inc. Treatment of angiopoietin like 7 (angptl7) related diseases
EP4061945A1 (en) * 2019-11-22 2022-09-28 Alnylam Pharmaceuticals, Inc. Ataxin3 (atxn3) rnai agent compositions and methods of use thereof
WO2022107106A2 (en) * 2020-11-23 2022-05-27 Phyzat Biopharmaceuticals, Lda Sina molecules, methods of production and uses thereof
WO2022254021A1 (en) * 2021-06-04 2022-12-08 Neumirna Therapeutics Aps Antisense oligonucleotides targeting adenosine kinase

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4845193A (en) 1992-09-11 1994-04-12 Regents Of The University Of California, The Adenosine analogues and method of increasing adenosine release
EP1368475A4 (en) * 2001-03-15 2004-10-20 Nuvelo Inc NEW NUCLEIC ACIDS AND NEW POLYPEPTIDES
WO2003064470A2 (en) * 2002-02-01 2003-08-07 Bayer Healthcare Ag Regulation of human calcium-activated potassium channel protein
US7273864B2 (en) 2002-10-15 2007-09-25 The Scripps Research Institute Compositions and methods for inducing osteogenesis
US20040241720A1 (en) * 2003-02-26 2004-12-02 Salkoff Lawrence B. Sodium activated potassium ion channel for therapeutic drug screening
US7592177B2 (en) 2003-11-10 2009-09-22 The Scripps Research Institute Compositions and methods for inducing cell dedifferentiation
EP1758651A2 (en) * 2004-06-24 2007-03-07 Galapagos N.V. Lxr agonists to promote bone homeostasis
WO2006017211A1 (en) 2004-07-12 2006-02-16 Research Development Foundation Guggulsterone as an inhibitor of nuclear factor-kb and ikbalpha kinase activation

Also Published As

Publication number Publication date
EP2049158A2 (en) 2009-04-22
JP2010500567A (ja) 2010-01-07
US7601501B2 (en) 2009-10-13
MX2009001372A (es) 2009-02-13
US20080038202A1 (en) 2008-02-14
AU2007281931A1 (en) 2008-02-14
WO2008019159A2 (en) 2008-02-14
CA2659437A1 (en) 2008-02-14
US20100184113A1 (en) 2010-07-22
EP2049158A4 (en) 2010-04-07
KR20090047508A (ko) 2009-05-12
WO2008019159A3 (en) 2009-04-16
RU2009108662A (ru) 2010-09-20
IL196760A0 (en) 2011-08-01

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]