BRPI0716691A2 - "processo para produzir um composto de Ácido bifosfânico" - Google Patents

"processo para produzir um composto de Ácido bifosfânico"

Info

Publication number
BRPI0716691A2
BRPI0716691A2 BRPI0716691-5A2A BRPI0716691A BRPI0716691A2 BR PI0716691 A2 BRPI0716691 A2 BR PI0716691A2 BR PI0716691 A BRPI0716691 A BR PI0716691A BR PI0716691 A2 BRPI0716691 A2 BR PI0716691A2
Authority
BR
Brazil
Prior art keywords
produce
acid compound
bisphosphonic acid
bisphosphonic
compound
Prior art date
Application number
BRPI0716691-5A2A
Other languages
English (en)
Inventor
Joana Baptista
Zita Mendes
Original Assignee
Hovione Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Int Ltd filed Critical Hovione Int Ltd
Publication of BRPI0716691A2 publication Critical patent/BRPI0716691A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0716691-5A2A 2006-11-06 2007-11-06 "processo para produzir um composto de Ácido bifosfânico" BRPI0716691A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT103600A PT103600B (pt) 2006-11-06 2006-11-06 Processo para a preparação de ácidos biosfónicos e seus sais farmaceuticamente aceitáveis
PCT/GB2007/004229 WO2008056129A1 (en) 2006-11-06 2007-11-06 Process for the preparation of biphosphonic acids and salts thereof

Publications (1)

Publication Number Publication Date
BRPI0716691A2 true BRPI0716691A2 (pt) 2013-09-17

Family

ID=38895608

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0716691-5A2A BRPI0716691A2 (pt) 2006-11-06 2007-11-06 "processo para produzir um composto de Ácido bifosfânico"

Country Status (14)

Country Link
US (1) US20090326227A1 (pt)
EP (1) EP2094717A1 (pt)
JP (1) JP2010508376A (pt)
CN (1) CN101605802A (pt)
AU (1) AU2007319040A1 (pt)
BR (1) BRPI0716691A2 (pt)
CA (1) CA2668783A1 (pt)
IL (1) IL198603A0 (pt)
NO (1) NO20091806L (pt)
NZ (1) NZ577343A (pt)
PT (1) PT103600B (pt)
RU (1) RU2425049C2 (pt)
WO (1) WO2008056129A1 (pt)
ZA (1) ZA200903228B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2016084A2 (en) * 2006-05-11 2009-01-21 Ind-Swift Laboratories Limited Process for the preparation of pure risedronic acid or salts
WO2009050731A2 (en) * 2007-06-20 2009-04-23 Alkem Laboratories Ltd Novel process for preparing risedronic acid
PL213599B1 (pl) 2008-10-31 2013-03-29 Politechnika Gdanska Sposób otrzymywania kwasu [1-hydroksy-2-(1H-imidazol-1-ilo)-etylideno] bisfosfonowego
EP2192126B1 (en) * 2008-11-26 2013-03-27 Synthon B.V. Process for making zoledronic acid
HU230718B1 (hu) 2011-02-08 2017-11-28 Richter Gedeon Nyrt. Új eljárás dronsavak gyógyszeripari előállítására
CN117986295A (zh) * 2022-10-27 2024-05-07 中国科学院赣江创新研究院 一种双膦酸类浮选药剂的制备方法及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77243A (en) 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
TW401276B (en) * 1993-10-07 2000-08-11 Zeneca Ltd Novel compounds and a method of controlling growth of plants
US6562974B2 (en) * 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
PL194770B1 (pl) 2001-03-19 2007-07-31 Adamed Sp Z Oo Sposób wytwarzania kwasu rizedronowego
ES2337063T3 (es) * 2003-08-21 2010-04-20 Sun Pharmaceuticals Industries Ltd. Proceso para la preparacion de acido bisfosfonico.
WO2005066188A1 (en) * 2003-10-17 2005-07-21 Sun Pharmaceutical Industries Limited A process for the preparation of 2-(imidazol-1-yl)-1-hydroxyethane-1, 1-diphosphonic acid
US7361761B2 (en) * 2004-09-28 2008-04-22 Orchid Chemicals & Pharmaceuticals Ltd. Process for the preparation of bisphosphonic acid
EP2610261A1 (en) * 2005-02-01 2013-07-03 F. Hoffmann-La Roche AG Ibandronate polymorph B
WO2006134603A1 (en) * 2005-06-13 2006-12-21 Jubilant Organosys Limited Process for producing bisphosphonic acids and forms thereof
WO2007010556A1 (en) * 2005-07-20 2007-01-25 Lupin Limited Process for the production of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
DE602006005597D1 (de) * 2005-12-27 2009-04-23 Ipca Lab Ltd Verbesserter Herstellungsprozess von 4-Amino-Hydroxybutyliden-1,1-bisphosphonischer Säure und ihrer Salze
WO2007096896A1 (en) * 2006-02-20 2007-08-30 Alembic Limited An improved process for the preparation of biphosphonic derivatives
CN101443341A (zh) * 2006-03-21 2009-05-27 雅宝公司 制造二膦酸的方法

Also Published As

Publication number Publication date
JP2010508376A (ja) 2010-03-18
CA2668783A1 (en) 2008-05-15
PT103600B (pt) 2009-01-30
RU2425049C2 (ru) 2011-07-27
NZ577343A (en) 2011-03-31
US20090326227A1 (en) 2009-12-31
RU2009121527A (ru) 2010-12-20
WO2008056129A1 (en) 2008-05-15
IL198603A0 (en) 2010-02-17
AU2007319040A1 (en) 2008-05-15
PT103600A (pt) 2008-05-30
EP2094717A1 (en) 2009-09-02
ZA200903228B (en) 2010-01-27
NO20091806L (no) 2009-07-02
CN101605802A (zh) 2009-12-16

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Legal Events

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B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 5A E 6A ANUIDADES.

B08I Publication cancelled [chapter 8.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A, 8A, 9A, 10A, 11A, 12A E 13A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.