BRPI0717462A2 - Emprego de valerato de estradiol ou 17 beta- estradiol em combinação com dienogest na terapia oral para manutenção e/ou aumento da libido feminin - Google Patents
Emprego de valerato de estradiol ou 17 beta- estradiol em combinação com dienogest na terapia oral para manutenção e/ou aumento da libido femininInfo
- Publication number
- BRPI0717462A2 BRPI0717462A2 BRPI0717462-4A2A BRPI0717462A BRPI0717462A2 BR PI0717462 A2 BRPI0717462 A2 BR PI0717462A2 BR PI0717462 A BRPI0717462 A BR PI0717462A BR PI0717462 A2 BRPI0717462 A2 BR PI0717462A2
- Authority
- BR
- Brazil
- Prior art keywords
- feminin
- betatradiol
- stradiol
- dienogest
- libido
- Prior art date
Links
- AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 title 1
- 229960003309 dienogest Drugs 0.000 title 1
- 238000012423 maintenance Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 229940070710 valerate Drugs 0.000 title 1
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06022091 | 2006-10-20 | ||
| EP07009373A EP1930010A1 (de) | 2006-10-20 | 2007-05-10 | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
| PCT/EP2007/008866 WO2008046559A1 (de) | 2006-10-20 | 2007-10-12 | VERWENDUNG VON ESTRADIOLVALERAT ODER 17ß-ESTRADIOL IN KOMBINATION MIT DIENOGEST ZUR ORALEN THERAPIE FÜR DEN ERHALT UND/ODER STEIGERUNG DER WEIBLICHEN LIBIDO |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0717462A2 true BRPI0717462A2 (pt) | 2013-12-24 |
Family
ID=38809728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0717462-4A2A BRPI0717462A2 (pt) | 2006-10-20 | 2007-10-12 | Emprego de valerato de estradiol ou 17 beta- estradiol em combinação com dienogest na terapia oral para manutenção e/ou aumento da libido feminin |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8349820B2 (pt) |
| EP (2) | EP1930010A1 (pt) |
| JP (1) | JP2010506867A (pt) |
| KR (1) | KR20090080989A (pt) |
| AU (1) | AU2007312626A1 (pt) |
| BR (1) | BRPI0717462A2 (pt) |
| CA (1) | CA2666829C (pt) |
| CO (1) | CO6160297A2 (pt) |
| CR (1) | CR10732A (pt) |
| EA (1) | EA016631B1 (pt) |
| GT (1) | GT200900090A (pt) |
| IL (1) | IL198200A (pt) |
| MX (1) | MX2009004179A (pt) |
| NO (1) | NO20091954L (pt) |
| NZ (1) | NZ576336A (pt) |
| SV (1) | SV2009003231A (pt) |
| WO (1) | WO2008046559A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004019743B4 (de) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| US8153616B2 (en) * | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| US20070088011A1 (en) * | 2005-10-17 | 2007-04-19 | Susan Zeun | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
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| AU4168068A (en) | 1969-07-22 | 1971-01-28 | Unisearch Limited | Improvements in or relating to oral contraceptives |
| US3639600A (en) | 1969-08-28 | 1972-02-01 | Upjohn Co | Process of establishing cyclicity in a human female |
| US3795734A (en) | 1970-04-20 | 1974-03-05 | American Home Prod | Cyclic regimen of hormone administration for contraception |
| US4066757A (en) | 1973-03-26 | 1978-01-03 | Ortho Pharmaceutical Corporation | Oral contraceptive regimen |
| DE2365103C3 (de) | 1973-12-21 | 1980-08-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | V erwendung von Hormonen zur Kontrazeption |
| DE2431704A1 (de) | 1974-07-02 | 1976-01-22 | Asche Ag | Stufenkombinationspraeparate per kontrazeption |
| DE2645307A1 (de) | 1976-10-05 | 1978-04-06 | Schering Ag | Neue mittel und neue methoden zur behandlung klimakterischer ausfallerscheinungen |
| NL8001593A (nl) | 1980-03-18 | 1981-10-16 | Akzo Nv | Meerfasisch combinatiepreparaat voor orale anticonceptie. |
| US4390531A (en) | 1981-08-10 | 1983-06-28 | Syntex Pharmaceuticals International Ltd. | Method of contraception using peak progestogen dosage |
| US4921843A (en) | 1988-10-20 | 1990-05-01 | Pasquale Samuel A | Contraception system and method |
| US4544554A (en) | 1983-09-26 | 1985-10-01 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
| US4628051A (en) | 1983-09-26 | 1986-12-09 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
| US4616006A (en) | 1983-09-26 | 1986-10-07 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
| US4530839A (en) | 1983-09-26 | 1985-07-23 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
| DE3341638A1 (de) | 1983-11-17 | 1984-05-03 | Hermann Dr.rer.nat. 8000 München Heßlinger | Dreiphasen-praeparat zur empfaengnisverhuetung aus ethinyloestradiol und lynestrenol |
| DE3347125A1 (de) | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption |
| AU581486B2 (en) | 1985-12-30 | 1989-02-23 | Warner-Lambert Company | Graduated estrogen contraceptive |
| IE61236B1 (en) | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
| CA2005933A1 (en) | 1989-01-09 | 1990-07-09 | Jesse Hipps, Sr. | Photohardenable composition containing five member aromatic group with imine moiety |
| IE71203B1 (en) | 1990-12-13 | 1997-02-12 | Akzo Nv | Low estrogen oral contraceptives |
| DE4104385C1 (pt) | 1991-02-09 | 1992-08-13 | Marika Dr.Med. 6509 Framersheim De Ehrlich | |
| DE4224534A1 (de) | 1992-07-24 | 1994-01-27 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
| DE4308406C1 (de) | 1993-03-12 | 1994-06-16 | Jenapharm Gmbh | Kombinationspräparat zur Kontrazeption |
| DE4313926A1 (de) | 1993-04-28 | 1994-11-03 | Jenapharm Gmbh | Pharmazeutisches Mehrphasenpräparat zur hormonalen Kontrazeption |
| DE4339934C2 (de) | 1993-05-07 | 1995-05-24 | Klaus Dr Med Umbreit | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
| NL9301562A (nl) | 1993-09-09 | 1995-04-03 | Saturnus Ag | Preparaat voor substitutietherapie. |
| DE4344462C2 (de) | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
| DE4429374C1 (de) | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| DE19525017A1 (de) | 1995-06-28 | 1997-01-02 | Schering Ag | Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption |
| DE19540253C2 (de) | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
| US20050032756A1 (en) * | 1995-10-28 | 2005-02-10 | Michael Dittgen | Multistage preparation for contraception based on natural estrogens |
| ES2229378T3 (es) | 1996-07-26 | 2005-04-16 | Wyeth | Anticonceptivo oral. |
| WO1998004269A1 (en) | 1996-07-26 | 1998-02-05 | American Home Products Corporation | Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen |
| AU3888597A (en) | 1996-07-26 | 1998-02-20 | American Home Products Corporation | Oral contraceptive |
| US5858405A (en) | 1996-07-26 | 1999-01-12 | American Home Products Corporation | Oral contraceptive |
| AU4043597A (en) | 1996-07-26 | 1998-02-20 | American Home Products Corporation | Biphasic contraceptive method and kit comprising a combination of a progestin and estrogen |
| DE19654609A1 (de) | 1996-12-20 | 1998-06-25 | Schering Ag | Therapeutische Gestagene zur Behandlung von Premenstrual Dysphoric Disorder |
| US6987101B1 (en) | 1996-12-20 | 2006-01-17 | Schering Aktiengesellschaft | Therapeutic gestagens for the treatment of premenstrual dysphoric disorder |
| US5898032A (en) | 1997-06-23 | 1999-04-27 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
| DE19908762A1 (de) | 1999-02-18 | 2000-08-31 | Jenapharm Gmbh | Verwendung von Dienogest in hoher Dosierung |
| DE10045380A1 (de) | 2000-09-14 | 2002-04-04 | Schering Ag | Verfahren zur Kontrazeption und dessen Darreichungsform |
| US6699820B2 (en) | 2001-03-02 | 2004-03-02 | Hartmut Ulrich Bielefeldt | Method for making a superconductor with enhanced current carrying capability |
| BRPI0208558A2 (pt) | 2001-09-29 | 2017-05-23 | Solvay Pharm Gmbh | preparado de combinação de estrogênio-gestagênio e uso |
| EP1462106A1 (en) | 2003-03-28 | 2004-09-29 | Pantarhei Bioscience B.V. | Pharmaceutical compositions and kits comprising 17-beta-estradiol and a progesteron for the treatment of gynecological disorders |
| JP2007528358A (ja) | 2003-06-25 | 2007-10-11 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | ジエノゲストを含んでなるホルモン置換療法および抑鬱療法 |
| DE102004019743B4 (de) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| MX2007004120A (es) | 2004-10-07 | 2007-06-15 | Duramed Pharmaceuticals Inc | Metodos de tratamiento hormonal utilizando regimentes de ciclo prolongado de dosis ascendente. |
| TW200726473A (en) | 2005-06-28 | 2007-07-16 | Wyeth Corp | Compositions and methods for treatment of cycle-related symptoms |
| DE502005006837D1 (de) | 2005-10-13 | 2009-04-23 | Bayer Schering Pharma Ag | Verwendung von Estradiolvalerat in Kombination mit Dienogest zur oralen Therapie der dysfunktionellen uterinen Blutung in Einheit mit einer oralen Kontrazeption |
| US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
-
2007
- 2007-05-10 EP EP07009373A patent/EP1930010A1/de not_active Withdrawn
- 2007-10-12 KR KR1020097010244A patent/KR20090080989A/ko not_active Ceased
- 2007-10-12 BR BRPI0717462-4A2A patent/BRPI0717462A2/pt not_active IP Right Cessation
- 2007-10-12 EA EA200900491A patent/EA016631B1/ru not_active IP Right Cessation
- 2007-10-12 WO PCT/EP2007/008866 patent/WO2008046559A1/de not_active Ceased
- 2007-10-12 JP JP2009532710A patent/JP2010506867A/ja active Pending
- 2007-10-12 NZ NZ576336A patent/NZ576336A/en not_active IP Right Cessation
- 2007-10-12 AU AU2007312626A patent/AU2007312626A1/en not_active Abandoned
- 2007-10-12 EP EP07818937A patent/EP2083827A1/de not_active Ceased
- 2007-10-12 MX MX2009004179A patent/MX2009004179A/es unknown
- 2007-10-12 CA CA2666829A patent/CA2666829C/en not_active Expired - Fee Related
- 2007-10-17 US US11/873,595 patent/US8349820B2/en not_active Expired - Fee Related
-
2009
- 2009-04-19 IL IL198200A patent/IL198200A/en not_active IP Right Cessation
- 2009-04-20 SV SV2009003231A patent/SV2009003231A/es unknown
- 2009-04-20 CO CO09039733A patent/CO6160297A2/es unknown
- 2009-04-20 CR CR10732A patent/CR10732A/es not_active Application Discontinuation
- 2009-04-20 GT GT200900090A patent/GT200900090A/es unknown
- 2009-05-19 NO NO20091954A patent/NO20091954L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080125401A1 (en) | 2008-05-29 |
| GT200900090A (es) | 2011-11-29 |
| WO2008046559A1 (de) | 2008-04-24 |
| IL198200A (en) | 2012-10-31 |
| JP2010506867A (ja) | 2010-03-04 |
| US8349820B2 (en) | 2013-01-08 |
| KR20090080989A (ko) | 2009-07-27 |
| CO6160297A2 (es) | 2010-05-20 |
| AU2007312626A1 (en) | 2008-04-24 |
| CA2666829A1 (en) | 2008-04-24 |
| NO20091954L (no) | 2009-05-19 |
| MX2009004179A (es) | 2009-04-30 |
| CA2666829C (en) | 2012-02-07 |
| IL198200A0 (en) | 2009-12-24 |
| EA200900491A1 (ru) | 2009-10-30 |
| NZ576336A (en) | 2012-03-30 |
| EP1930010A1 (de) | 2008-06-11 |
| SV2009003231A (es) | 2009-11-09 |
| EP2083827A1 (de) | 2009-08-05 |
| CR10732A (es) | 2009-05-25 |
| EA016631B1 (ru) | 2012-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2277 DE 26/08/2014. |