BRPI0808104A8 - Métodos para preparar e para produzir um polipeptídeo, polipeptídeo, sequência de ácido nucleico isolada, construção de ácido nucleico, vetor de expressão recombinante, e, célula hospedeira recombinante - Google Patents

Métodos para preparar e para produzir um polipeptídeo, polipeptídeo, sequência de ácido nucleico isolada, construção de ácido nucleico, vetor de expressão recombinante, e, célula hospedeira recombinante

Info

Publication number
BRPI0808104A8
BRPI0808104A8 BRPI0808104A BRPI0808104A BRPI0808104A8 BR PI0808104 A8 BRPI0808104 A8 BR PI0808104A8 BR PI0808104 A BRPI0808104 A BR PI0808104A BR PI0808104 A BRPI0808104 A BR PI0808104A BR PI0808104 A8 BRPI0808104 A8 BR PI0808104A8
Authority
BR
Brazil
Prior art keywords
polypeptide
nucleic acid
methods
host cell
preparing
Prior art date
Application number
BRPI0808104A
Other languages
English (en)
Inventor
Matsui Tomoko
Peter Friis Esben
Yamagishi Akihiko
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39577873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0808104(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Publication of BRPI0808104A2 publication Critical patent/BRPI0808104A2/pt
Publication of BRPI0808104A8 publication Critical patent/BRPI0808104A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
    • A23L19/12—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops of potatoes
    • A23L19/18—Roasted or fried products, e.g. snacks or chips
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01001—Asparaginase (3.5.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

MÉTODOS PARA PREPARAR E PARA PRODUZIR UM POLIPEPTÍDEO, POLIPEPTÍDEO, SEQUÊNCIA DE ÁCIDO NUCLEICO ISOLADA, CONSTRUÇÃO DE ÁCIDO NUCLEICO, VETOR DE EXPRESSÃO RECOMBINANTE, E, CÉLULA HOSPEDEIRA RECOMBINANTE. A invenção refere-se a novas asparginases tendo propriedades melhoradas, termotolerância preferivelmente melhorada, tal como atividade melhorada em temperaturas altas e/ou termoestabilidade melhorada. A invenção também refere-se a sequências de DNA que codificam tais asparaginases melhoradas, sua produção em uma célula hospedeira recombinante, bem como métodos de usar as asparaginaes em particular para a redução de acrilamida em alimentos. A invenção ainda refere-se a métodos de gerar e preparar variantes de asparaginase tendo propriedades melhoradas.
BRPI0808104A 2007-03-09 2008-03-07 Métodos para preparar e para produzir um polipeptídeo, polipeptídeo, sequência de ácido nucleico isolada, construção de ácido nucleico, vetor de expressão recombinante, e, célula hospedeira recombinante BRPI0808104A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07103862 2007-03-09
PCT/EP2008/052759 WO2008110513A1 (en) 2007-03-09 2008-03-07 Thermostable asparaginases

Publications (2)

Publication Number Publication Date
BRPI0808104A2 BRPI0808104A2 (pt) 2015-03-24
BRPI0808104A8 true BRPI0808104A8 (pt) 2017-05-02

Family

ID=39577873

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0808104A BRPI0808104A8 (pt) 2007-03-09 2008-03-07 Métodos para preparar e para produzir um polipeptídeo, polipeptídeo, sequência de ácido nucleico isolada, construção de ácido nucleico, vetor de expressão recombinante, e, célula hospedeira recombinante

Country Status (9)

Country Link
US (3) US7666652B2 (pt)
EP (2) EP2137307B1 (pt)
CN (1) CN101641439B (pt)
AU (1) AU2008225859B2 (pt)
BR (1) BRPI0808104A8 (pt)
CA (1) CA2680273C (pt)
DK (2) DK2851424T3 (pt)
ES (1) ES2519466T3 (pt)
WO (1) WO2008110513A1 (pt)

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DE102007027825A1 (de) 2007-06-13 2008-12-18 C-Lecta Gmbh Amidohydrolasen zur Aufbereitung von Nahrungs- oder Genussmitteln
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WO2011003633A1 (en) 2009-07-06 2011-01-13 Alize Pharma Ii Pegylated l-asparaginase
RU2603061C2 (ru) * 2010-03-02 2016-11-20 Ренессанс Байосайенс Корп., Функциональное улучшение микроорганизмов для минимизации продукции акриламида
US20120100249A1 (en) * 2010-04-27 2012-04-26 Dsm Ip Assets B.V. Novel asparaginase enzyme
WO2012007192A1 (en) * 2010-07-14 2012-01-19 Nestec S.A. Asparaginase from basidiomycetes
US9057087B2 (en) 2010-11-19 2015-06-16 Novozymes North America, Inc. Processes of producing a fermentation product
WO2012158320A1 (en) 2011-05-13 2012-11-22 Baker Hughes Incorporated Method of using asparaginase as a polyacrylamide enzyme breaker
CN103060299B (zh) * 2011-10-19 2017-05-03 北京安百胜生物科技有限公司 活性提高的l‑天冬酰胺酶变体
PL2884857T3 (pl) * 2012-08-17 2017-07-31 Novozymes A/S Sposób wytwarzania produktu żywnościowego
US9828595B2 (en) * 2012-08-17 2017-11-28 Novozymes A/S Thermostable asparaginase variants and polynucleotides encoding same
US9068171B2 (en) 2012-09-06 2015-06-30 Mycotechnology, Inc. Method for myceliating coffee
US9427008B2 (en) 2012-09-06 2016-08-30 Mycotechnology, Inc. Method of myceliation of agricultural substates for producing functional foods and nutraceuticals
US20160037807A1 (en) * 2013-04-05 2016-02-11 Novozymes A/S Method for Reducing the Level of Asparagine in a Food Material
US10231469B2 (en) 2014-03-15 2019-03-19 Mycotechnology, Inc. Myceliated products and methods for making myceliated products from cacao and other agricultural substrates
WO2016001894A1 (en) 2014-07-04 2016-01-07 West Systems Srl Method and composition to reduce the formation of acrylamide in fresh or pre-fried foods to be subjected to heat treatment
US9572364B2 (en) 2014-08-26 2017-02-21 Mycotechnology, Inc. Methods for the production and use of mycelial liquid tissue culture
US10709157B2 (en) 2014-08-26 2020-07-14 Mycotechnology, Inc. Methods for the production and use of mycelial liquid tissue culture
EP3185700B1 (en) 2014-08-26 2021-07-28 Mycotechnology, Inc. Methods for the production and use of mycelial liquid tissue culture
WO2016138476A1 (en) 2015-02-26 2016-09-01 Mycotechnology, Inc. Methods for lowering gluten content using fungal cultures
US10806101B2 (en) 2016-04-14 2020-10-20 Mycotechnology, Inc. Methods for the production and use of myceliated high protein food compositions
EP3981260A1 (en) 2016-04-14 2022-04-13 Mycotechnology, Inc. Methods for the production and use of myceliated high protein food compositions
US11166477B2 (en) 2016-04-14 2021-11-09 Mycotechnology, Inc. Myceliated vegetable protein and food compositions comprising same
IL271504B2 (en) * 2017-06-21 2024-05-01 Jazz Pharmaceuticals Ireland Ltd Modified l-asparaginase
US10174302B1 (en) 2017-06-21 2019-01-08 Xl-Protein Gmbh Modified L-asparaginase
JP2021520828A (ja) * 2018-04-19 2021-08-26 キンドレッド バイオサイエンシズ インコーポレイテッド 医療用の変異体アスパラギナーゼポリペプチド
US20210299233A1 (en) 2018-07-12 2021-09-30 The Children's Medical Center Corporation Method for treating cancer
US12274283B2 (en) 2018-09-20 2025-04-15 The Better Meat Co. Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions
US11058137B2 (en) 2018-09-20 2021-07-13 The Better Meat Co. Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions
CN109266635B (zh) * 2018-11-20 2020-12-01 江南大学 一种酶活提高的l-天冬酰胺酶突变体及其构建方法
US20220213461A1 (en) * 2019-05-07 2022-07-07 Nanyang Technological University Asx-specific protein ligases and uses thereof
CN110256535B (zh) * 2019-06-14 2021-01-01 中国石油大学(华东) L-天门冬酰胺酶XiDL及其编码基因和应用
CN112941059B (zh) * 2021-02-23 2022-03-15 江南大学 一种l-天冬酰胺酶突变体及其在枯草芽孢杆菌中的表达
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Also Published As

Publication number Publication date
EP2851424B1 (en) 2016-09-21
US7666652B2 (en) 2010-02-23
US20100055726A1 (en) 2010-03-04
CN101641439A (zh) 2010-02-03
BRPI0808104A2 (pt) 2015-03-24
DK2851424T3 (en) 2017-01-16
AU2008225859B2 (en) 2014-06-26
WO2008110513A1 (en) 2008-09-18
ES2519466T3 (es) 2014-11-07
US20100221385A1 (en) 2010-09-02
DK2137307T3 (da) 2014-11-03
CN101641439B (zh) 2016-05-25
US7829320B2 (en) 2010-11-09
EP2137307A1 (en) 2009-12-30
EP2137307B1 (en) 2014-07-30
US7871806B2 (en) 2011-01-18
CA2680273C (en) 2017-02-28
CA2680273A1 (en) 2008-09-18
US20090170157A1 (en) 2009-07-02
EP2851424A1 (en) 2015-03-25
AU2008225859A1 (en) 2008-09-18

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: C12N 9/82 (2006.01), C12N 15/52 (2006.01), A23L 5/

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]