BRPI0809346A2 - Compostos derivados substituídos de imidazopiridina e composição farmacêutica contendo os mesmos - Google Patents

Compostos derivados substituídos de imidazopiridina e composição farmacêutica contendo os mesmos

Info

Publication number
BRPI0809346A2
BRPI0809346A2 BRPI0809346-6A2A BRPI0809346A BRPI0809346A2 BR PI0809346 A2 BRPI0809346 A2 BR PI0809346A2 BR PI0809346 A BRPI0809346 A BR PI0809346A BR PI0809346 A2 BRPI0809346 A2 BR PI0809346A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
same
composition containing
derivative compounds
substituted imidazopyridine
Prior art date
Application number
BRPI0809346-6A2A
Other languages
English (en)
Inventor
Guenther Metz
Achim Feurer
Sonja Nordhoff
Christian Rummey
Ulrich Abel
Holger Deppe
Inge Ott
Michael Soeberdt
Barbara Hoffmann-Enger
Philipp Weyermann
Herve Siendt
Miroslav Terinek
Marco Henneboehle
Holger Herzner
Cesare Mondadori
Original Assignee
Santhera Pharmaceuticals Ch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santhera Pharmaceuticals Ch filed Critical Santhera Pharmaceuticals Ch
Publication of BRPI0809346A2 publication Critical patent/BRPI0809346A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BRPI0809346-6A2A 2007-03-28 2008-03-28 Compostos derivados substituídos de imidazopiridina e composição farmacêutica contendo os mesmos BRPI0809346A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92050007P 2007-03-28 2007-03-28
EP07006422A EP1974729A1 (en) 2007-03-28 2007-03-28 Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
PCT/EP2008/002498 WO2008116665A1 (en) 2007-03-28 2008-03-28 Substituted imidazopyridine derivatives as melanocortin-4 receptor antagonists

Publications (1)

Publication Number Publication Date
BRPI0809346A2 true BRPI0809346A2 (pt) 2014-10-07

Family

ID=38335635

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809346-6A2A BRPI0809346A2 (pt) 2007-03-28 2008-03-28 Compostos derivados substituídos de imidazopiridina e composição farmacêutica contendo os mesmos

Country Status (13)

Country Link
US (1) US8236818B2 (pt)
EP (2) EP1974729A1 (pt)
JP (1) JP2010522224A (pt)
KR (1) KR101128140B1 (pt)
CN (1) CN101663301B (pt)
AU (1) AU2008231977B2 (pt)
BR (1) BRPI0809346A2 (pt)
CA (1) CA2682329C (pt)
IL (1) IL200804A0 (pt)
MX (1) MX2009010429A (pt)
NZ (1) NZ579513A (pt)
RU (1) RU2451684C2 (pt)
WO (1) WO2008116665A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2072516A1 (en) * 2007-12-21 2009-06-24 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as Melancortin-4 receptor antagonists
EP2072050A1 (en) * 2007-12-21 2009-06-24 Santhera Pharmaceuticals (Schweiz) AG Compounds with anti-emetic effect
EP2300470A2 (en) 2008-05-19 2011-03-30 Sepracor Inc. Imidazo[1,2-a]pyridine compounds as gaba-a receptor modulators
ES2563232T3 (es) 2011-07-29 2016-03-11 Taisho Pharmaceutical Co., Ltd. Compuesto de amidina o sal del mismo
CA3301962A1 (en) 2011-12-29 2026-03-02 Rhythm Pharmaceuticals, Inc. Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers
WO2014187922A1 (en) 2013-05-24 2014-11-27 Iomet Pharma Ltd. Slc2a transporter inhibitors
PT3356386T (pt) 2015-09-30 2024-05-17 Rhythm Pharmaceuticals Inc Método de tratamento de distúrbios associados à via do receptor da melanocortina-4
CN108699084A (zh) * 2015-12-10 2018-10-23 拜耳制药股份公司 取代全氢吡咯并[3,4-c]吡咯衍生物及其用途
MX2018007040A (es) 2015-12-10 2018-08-15 Bayer Pharma AG Derivados de 2-fenil-3-(piperazinometil) imidazo[1,2-a] piridina como bloqueadores de los canales task-1 y task-2 para el tratamiento de trastornos respiratorios relacionados con el sueño.
CA3027500A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
JP7054529B2 (ja) * 2016-06-21 2022-04-14 エックス４ ファーマシューティカルズ， インコーポレイテッド Ｃｘｃｒ４阻害剤およびその使用
WO2017223229A1 (en) * 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
CN110352192B (zh) 2016-09-16 2023-03-24 住友化学株式会社 杂环化合物及含有其的有害节肢动物防治剂
JOP20190284A1 (ar) 2017-06-14 2019-12-11 Bayer Pharma AG مركبات إيميدازوبيريميدين مستبدلة بديازا ثنائي الحلقة واستخدامها للمعالجة من اضطرابات التنفس
MD3762368T2 (ro) 2018-03-08 2022-07-31 Incyte Corp Compuși diol aminopirazină ca inhibitori ai PI3K-Y
WO2019178129A1 (en) 2018-03-13 2019-09-19 Shire Human Genetic Therapies, Inc. Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof
CN111918865B (zh) 2018-03-30 2023-10-27 住友化学株式会社 杂环化合物和含有该杂环化合物的有害节肢动物防除组合物
AU2019249255A1 (en) 2018-04-06 2020-11-05 Alastair GARFIELD Compositions for treating kidney disease
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
WO2020120477A1 (en) * 2018-12-11 2020-06-18 Sanofi Insulin analogs having reduced insulin receptor binding affinity
US11370803B2 (en) 2019-09-18 2022-06-28 Takeda Pharmaceutical Company Limited Heteroaryl plasma kallikrein inhibitors
PT4031547T (pt) 2019-09-18 2024-08-27 Takeda Pharmaceuticals Co Inibidores de calicreína plasmática e utilizações dos mesmos
AU2020399194A1 (en) * 2019-12-10 2022-07-28 Sanofi A method of forming a conjugate of a sulfonamide and a polypeptide
CN114805237B (zh) * 2021-01-22 2026-04-21 武汉人福创新药物研发中心有限公司 杂环类化合物的制备方法及其中间体
CN113666926A (zh) * 2021-09-08 2021-11-19 桂林理工大学 一种便捷的2-苯基咪唑[1,2-a]吡啶与查尔酮的Michal加成反应

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593818B1 (fr) * 1986-02-05 1988-04-29 Synthelabo Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
US7375125B2 (en) * 1999-08-04 2008-05-20 Ore Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
PT1218382E (pt) * 1999-10-08 2004-06-30 Gruenenthal Gmbh Derivados de imidazo-3-il-amina biciclica
ES2279837T3 (es) * 2000-11-20 2007-09-01 Scios Inc. Inhibidores de tipo piperidina/piperazina de la quinasa p38.
SE0100568D0 (sv) * 2001-02-20 2001-02-20 Astrazeneca Ab Compounds
IL159811A0 (en) 2001-07-13 2004-06-20 Neurogen Corp Heteroaryl substituted fused bicyclic heteroaryl compounds as gabaa receptor ligands

Also Published As

Publication number Publication date
CA2682329A1 (en) 2008-10-02
US8236818B2 (en) 2012-08-07
US20100093697A1 (en) 2010-04-15
CN101663301A (zh) 2010-03-03
IL200804A0 (en) 2010-05-17
EP1974729A1 (en) 2008-10-01
JP2010522224A (ja) 2010-07-01
AU2008231977A1 (en) 2008-10-02
WO2008116665A8 (en) 2008-12-11
CN101663301B (zh) 2012-06-06
CA2682329C (en) 2012-03-27
EP2144907A1 (en) 2010-01-20
RU2009134038A (ru) 2011-05-10
RU2451684C2 (ru) 2012-05-27
NZ579513A (en) 2011-03-31
WO2008116665A1 (en) 2008-10-02
AU2008231977B2 (en) 2011-03-24
KR20090122309A (ko) 2009-11-26
KR101128140B1 (ko) 2012-03-23
MX2009010429A (es) 2009-10-20

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.