BRPI0809707A2 - cassete de reação para medir a concentração de hemoglobina glicosada e método de medição a partir deste. - Google Patents

cassete de reação para medir a concentração de hemoglobina glicosada e método de medição a partir deste.

Info

Publication number
BRPI0809707A2
BRPI0809707A2 BRPI0809707A BRPI0809707A BRPI0809707A2 BR PI0809707 A2 BRPI0809707 A2 BR PI0809707A2 BR PI0809707 A BRPI0809707 A BR PI0809707A BR PI0809707 A BRPI0809707 A BR PI0809707A BR PI0809707 A2 BRPI0809707 A2 BR PI0809707A2
Authority
BR
Brazil
Prior art keywords
reaction
reagent
blood sample
reaction cassette
zone
Prior art date
Application number
BRPI0809707A
Other languages
English (en)
Inventor
Bae Byeong-Woo
Kim Hyoung-Soo
Hong Ju-Pyo
Yoo Jae-Hyun
Lee Ki-Won
Kim Min-Sun
Lee Sung-Dong
Original Assignee
Infopia Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39219456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0809707(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Infopia Co Ltd filed Critical Infopia Co Ltd
Publication of BRPI0809707A2 publication Critical patent/BRPI0809707A2/pt
Publication of BRPI0809707B1 publication Critical patent/BRPI0809707B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/726—Devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

cassete de reação para medir a concentração de hemoglobina glicosada e método de medição a partir deste. um cassete para reação para um medidor de hemoglobina glicosada e um método para a medição em conseqüência disso são apresentados. o cassete de reação para o medidor de hemoglobina glicosada inclui: uma primeira zona a qual recebe um primeiro reagente e uma amostra de sangue; uma segunda zona a qual recebe um segundo reagente; uma zona de reação na qual o sangue reage com o primeiro reagente, ou através da qual o segundo reagente passa a reagir com uma primeira mistura de amostra de sangue, amostra a qual é obtida por meio da reação da amostra de sangue com o primeiro reagente; e uma zona para a medição a qual mede uma quantidade total de hemoglobina na primeira mistura de amostra de sangue, ou mede uma quantidade de hemoglobina glicosada em uma segunda amostra de sangue, a qual é obtida por meio da reação da mistura da primeira amostra de sangue com o segundo reagente, onde que na amostra de sangue, o primeiro reagente, e o segundo reagente se movem entre a zona de reação e a zona de medição de acordo com um ângulo de rotação do cassete de reação, quando o cassete de reação é girado. desta forma, uma vez que cassete de reação sofre a rotação de forma automática, é possível medir a quantidade de hemoglobina glicosada em uma amostra de sangue através de simples manipulação e desta forma se reduz um tempo de produção. além do mais, uma vez que os reagentes são fornecidos no cassete de reação a partir de um pacote de reação separado, é possível resolver o problema de armazenamento e de distribuição do cassete de reação, o que ocorre quando os reagentes são armazenados no cassete de reação.
BRPI0809707-0A 2007-10-08 2008-06-24 cassete de reação para um medidor de hemoglobina glicosada e método de medição a partir deste BRPI0809707B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2007-0101116 2007-10-08
KR1020070101116A KR100798471B1 (ko) 2007-10-08 2007-10-08 당화혈색소 측정카세트 및 이를 이용한 당화혈색소측정방법
PCT/KR2008/003587 WO2009048217A1 (en) 2007-10-08 2008-06-24 Reaction cassette for measuring the concentration of glycated hemoglobin and measuring method thereof

Publications (2)

Publication Number Publication Date
BRPI0809707A2 true BRPI0809707A2 (pt) 2019-03-19
BRPI0809707B1 BRPI0809707B1 (pt) 2021-04-20

Family

ID=39219456

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809707-0A BRPI0809707B1 (pt) 2007-10-08 2008-06-24 cassete de reação para um medidor de hemoglobina glicosada e método de medição a partir deste

Country Status (8)

Country Link
US (1) US8846380B2 (pt)
EP (3) EP2047909B1 (pt)
JP (1) JP4904507B2 (pt)
KR (1) KR100798471B1 (pt)
CN (1) CN101408549B (pt)
BR (1) BRPI0809707B1 (pt)
RU (1) RU2473084C2 (pt)
WO (1) WO2009048217A1 (pt)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101128037B1 (ko) * 2009-06-19 2012-03-29 주식회사 인포피아 당화혈색소 측정 방법
KR101069823B1 (ko) * 2009-06-19 2011-10-04 주식회사 인포피아 당화혈색소 측정용 카세트
CN102460159A (zh) * 2009-06-19 2012-05-16 因福皮亚有限公司 用于测量糖化血红蛋白的方法
TWI414771B (zh) * 2009-11-03 2013-11-11 Apex Biotechnology Corp 反應卡匣、檢測裝置、及檢測方法
CN103140755B (zh) 2010-07-22 2016-03-16 哈希公司 用于碱度分析的芯片上实验室
JP5467140B2 (ja) * 2011-11-10 2014-04-09 エイペックス バイオテクノロジー コーポレイション 生化学アッセイ装置
KR101355126B1 (ko) * 2012-04-24 2014-01-29 주식회사 아이센스 생화학 분석 카트리지
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
KR101352900B1 (ko) * 2012-07-31 2014-01-23 주식회사 아이센스 조작성이 향상된 생화학 분석 카트리지
JP6011156B2 (ja) * 2012-08-24 2016-10-19 ブラザー工業株式会社 検査チップ
JP2014048194A (ja) * 2012-08-31 2014-03-17 Brother Ind Ltd 検査チップおよび検査ユニット
JP5998760B2 (ja) * 2012-08-31 2016-09-28 ブラザー工業株式会社 試薬容器および検査チップ
KR20140032221A (ko) * 2012-09-06 2014-03-14 삼성전자주식회사 시료 중의 당화 단백질을 확인하는 방법 및 그를 위한 장치
CN103823071B (zh) * 2012-11-16 2016-12-21 北京怡成生物电子技术股份有限公司 “磁珠‑糖化血红蛋白‑二茂铁硼酸”复合物及其应用
KR101959445B1 (ko) * 2012-11-30 2019-03-18 삼성전자주식회사 시료 중의 당화 단백질을 측정하는 카트리지 및 이를 이용한 당화 단백질 측정 방법
KR101995253B1 (ko) * 2012-12-03 2019-07-02 엘지전자 주식회사 카트리지형 당화혈색소 검출 장치 및 방법
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
KR101412423B1 (ko) 2013-06-25 2014-06-27 주식회사 인포피아 검체 함유 유닛, 검체 측정 카세트, 검체 측정 유닛 및 검체 측정 장치
US20160202275A1 (en) 2013-06-25 2016-07-14 Infopia Co., Ltd. Specimen containing unit, specimen measurement cassette, specimen measurement unit, and specimen measurement device
JP2015114197A (ja) * 2013-12-11 2015-06-22 東ソー株式会社 乾燥分離材を用いた分離方法及び測定方法
US10288628B2 (en) * 2014-04-11 2019-05-14 Siemens Healthcare Diagnostics Inc. Spectroscopic methods for the detection of glycated hemoglobin
KR101663600B1 (ko) * 2014-07-28 2016-10-10 (주)세종바이오 앱타머 기반 혈중 당화헤모글로빈 측정용 카트리지
EP2982436B1 (en) * 2014-08-04 2020-09-09 Skyla Corporation Hsinchu Science Park Branch Testing module for testing a sample
US10493448B2 (en) * 2015-03-13 2019-12-03 Bio-Rad Laboratories, Inc. Assay cartridge
US10634602B2 (en) 2015-06-12 2020-04-28 Cytochip Inc. Fluidic cartridge for cytometry and additional analysis
CN113791203B (zh) 2015-06-12 2024-05-17 芯易诊有限公司 用于分析生物样品的方法
CN105021807B (zh) * 2015-07-03 2016-08-31 艾康生物技术(杭州)有限公司 试剂反应盒及其在生物样品检测中的应用
CN105013546B (zh) 2015-07-03 2017-12-08 艾康生物技术(杭州)有限公司 生物样品反应盒
CN105137091B (zh) * 2015-07-03 2017-10-10 艾康生物技术(杭州)有限公司 试剂存储器
CN105021544B (zh) 2015-07-03 2018-02-02 艾康生物技术(杭州)有限公司 检测系统
CN108027310B (zh) 2015-07-14 2020-12-22 芯易诊有限公司 流体盒中的体积感测
CN105606418A (zh) * 2015-12-30 2016-05-25 李新华 一种检测糖化血红蛋白的一体化试剂盒及其检测方法
US10436773B2 (en) 2016-01-18 2019-10-08 Jana Care, Inc. Mobile device based multi-analyte testing analyzer for use in medical diagnostic monitoring and screening
ES2935417T3 (es) * 2016-03-30 2023-03-06 Osang Healthcare Co Ltd Casete de verificación, dispositivo de medición, sistema para compensar intensidad de luz de fuente de luz para dispositivo de medición, método para compensar intensidad de luz de fuente de luz para dispositivo de medición, y medio de grabación
CA3031064C (en) * 2016-07-18 2022-12-06 Siemens Healthcare Diagnostics Inc. Liquid analytical reagent dispensing apparatus and analytical kits and methods of use related thereto
WO2018043779A1 (ko) * 2016-09-05 2018-03-08 주식회사 녹십자엠에스 당화혈색소 측정용 일체형 카세트
EP3521830B1 (en) * 2016-09-29 2025-04-23 Green Cross Medical Science Separable cassette for measuring glycated hemoglobin
WO2018077983A1 (en) 2016-10-26 2018-05-03 Radisens Diagnostics Limited A point-of-care diagnostic assay cartridge
US11226344B2 (en) 2016-11-04 2022-01-18 Green Cross Medical Science Measurement method for glycated hemoglobin ratio
CN107255724A (zh) * 2017-01-03 2017-10-17 深圳市惠安生物科技有限公司 糖化血红蛋白的即时检验试剂装置及其制备方法
CN107290310A (zh) * 2017-06-05 2017-10-24 天津三箭生物技术股份有限公司 糖化血红蛋白检测试剂盒（荧光淬灭法）制备方法
WO2019083844A1 (en) 2017-10-23 2019-05-02 Cytochip Inc. DEVICES AND METHOD FOR MEASURING TARGET ANALYTES AND PARTICLES
US10624569B2 (en) * 2018-02-01 2020-04-21 Tyson Bioresearch, Inc. Method of increasing reading barcode information
CN109212235A (zh) * 2018-08-31 2019-01-15 深圳市国赛生物技术有限公司 Poct糖化血红蛋白分析仪和poct糖化血红蛋白分析系统
CN111198269B (zh) * 2018-11-20 2023-12-12 杭州微策生物技术股份有限公司 一种生物流体样本检测试剂盒及检测系统与应用
CN111198268B (zh) * 2018-11-20 2023-12-12 杭州微策生物技术股份有限公司 一种生物流体样本检测试剂盒及其检测系统与应用
US11460476B2 (en) * 2019-03-04 2022-10-04 Siemens Healthcare Diagnostics Inc. Dye-based liquid reagent volume indicator for use in analyte detection assays
CN110596409B (zh) * 2019-08-16 2020-12-29 深圳市朴瑞生物科技有限公司 应用于快速即时检测的试剂包及其检测设备
GB201915499D0 (en) 2019-10-25 2019-12-11 Radisens Diagnostics Ltd A point-of-care test cartridge
US11536732B2 (en) 2020-03-13 2022-12-27 Jana Care, Inc. Devices, systems, and methods for measuring biomarkers in biological fluids
KR102609317B1 (ko) * 2021-04-16 2023-12-04 (주)케어포유 혈액 분석용 카세트
KR102538067B1 (ko) * 2021-04-26 2023-05-31 (주)오상헬스케어 당화혈색소 측정카세트
US11852577B2 (en) 2021-09-29 2023-12-26 Orange Biomed Ltd., Co. Apparatus for measuring properties of particles in a solution and related methods
US12517109B2 (en) 2022-12-09 2026-01-06 Orange Biomed Ltd., Co. Sample-testing system for measuring properties of red blood cells
WO2025119902A1 (en) * 2023-12-04 2025-06-12 F. Hoffmann-La Roche Ag Hemoglobin determination methods and systems

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883763A (en) * 1984-05-03 1989-11-28 Abbott Laboratories Sample processor card for centrifuge
US4818850A (en) 1987-07-10 1989-04-04 Clinicom Incorporated Method and apparatus for attaching bar code indicia on items
US5162237A (en) * 1988-04-11 1992-11-10 Miles Inc. Reaction cassette for preforming sequential analytical assays by noncentrifugal and noncapillary manipulations
US4990075A (en) 1988-04-11 1991-02-05 Miles Inc. Reaction vessel for performing sequential analytical assays
US5807747A (en) * 1989-06-13 1998-09-15 Clinical Innovations Limited Method and apparatus for determination of glycosylated protein
IL94408A0 (en) * 1989-07-11 1991-03-10 Miles Inc Method,reaction cassette and kit for performing analytical assays
US5120503A (en) 1989-07-14 1992-06-09 Eastman Kodak Company Extracting device for extracting antigens
CA2029611A1 (en) * 1989-12-04 1991-06-05 Bruce A. Flora Heating device with a phase change temperature controller
US5304348A (en) * 1992-02-11 1994-04-19 Abaxis, Inc. Reagent container for analytical rotor
US5372948A (en) * 1993-03-17 1994-12-13 Miles Inc. Assay and reaction vessel with a compartmentalized solubilization chamber
JPH07175900A (ja) 1993-12-20 1995-07-14 Nec Corp バーコードシンボルおよびそのリーダ
JP3651613B2 (ja) 1995-11-29 2005-05-25 三洋電機株式会社 表示装置および表示装置の製造方法
GB9620278D0 (en) * 1996-09-28 1996-11-13 Central Research Lab Ltd Apparatus for chemical analysis
WO1999028038A1 (en) 1997-11-28 1999-06-10 Cortecs Diagnostics Limited Device and apparatus for conducting an assay
US6174728B1 (en) 1998-04-03 2001-01-16 Avl Medical Instruments Ag Control or calibration standard for use with instruments for optical measurement of hemoglobin concentration in blood samples
JP2000284349A (ja) * 1999-03-30 2000-10-13 Fuji Photo Film Co Ltd 撮像装置
GB9913560D0 (en) * 1999-06-10 1999-08-11 Cortecs Diagnostics Limited Mixing apparatus and method of mixing
GB0021887D0 (en) * 2000-09-06 2000-10-18 Provalis Diagnostics Ltd Assay device
US6677158B2 (en) * 2001-03-14 2004-01-13 Exocell Inc. Method for measurement of glycated hemoglobin by a rapid strip test procedure
DK1390760T3 (da) * 2001-05-09 2008-10-20 Axis Shield Asa Assaysystem
US6562581B2 (en) 2001-08-31 2003-05-13 Portascience Method for quantitative determination of glycated hemoglobin
GB0121340D0 (en) * 2001-09-04 2001-10-24 Provalis Diagnostics Ltd Device fo9r use in fluid array
KR20040018893A (ko) 2002-08-27 2004-03-04 주식회사 바이오포커스 면역크로마토그라피법을 이용한 당화혈색소 진단 킷트 및분석 방법
RU2363951C2 (ru) * 2003-10-29 2009-08-10 Мек Динамикс Корп. Микромеханические способы и устройства для проведения анализов
KR100602952B1 (ko) 2004-07-26 2006-07-24 주식회사 인포피아 면역크로마토그래피법을 이용한 당화혈색소 측정센서
WO2006011393A1 (ja) * 2004-07-29 2006-02-02 Matsushita Electric Industrial Co., Ltd. 分析装置、分析用ディスクおよびそれらを備えた分析システム
JP2006105638A (ja) * 2004-10-01 2006-04-20 Hitachi High-Technologies Corp 化学分析装置
JP4623716B2 (ja) * 2004-11-25 2011-02-02 旭化成株式会社 核酸検出用カートリッジ及び核酸検出方法
KR100662021B1 (ko) 2005-12-30 2006-12-27 주식회사 인포피아 바이오 카트리지
JP2007198949A (ja) * 2006-01-27 2007-08-09 Matsushita Electric Ind Co Ltd 分析用ディスク、及び分析装置
CN1888902B (zh) * 2006-08-11 2011-05-18 杭州优思达生物技术有限公司 全封闭式靶核酸扩增物快速检测装置

Also Published As

Publication number Publication date
EP2047909A3 (en) 2009-08-19
EP3047907A1 (en) 2016-07-27
RU2009137974A (ru) 2011-04-20
WO2009048217A1 (en) 2009-04-16
EP3047908A1 (en) 2016-07-27
BRPI0809707B1 (pt) 2021-04-20
JP2009092643A (ja) 2009-04-30
CN101408549B (zh) 2013-07-10
JP4904507B2 (ja) 2012-03-28
US20090093012A1 (en) 2009-04-09
RU2473084C2 (ru) 2013-01-20
EP2047909A2 (en) 2009-04-15
EP2047909B1 (en) 2016-04-13
CN101408549A (zh) 2009-04-15
KR100798471B1 (ko) 2008-01-28
US8846380B2 (en) 2014-09-30

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