BRPI0810446A2 - Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin-4-il)- 5-(metóxi)piridina-2-carboxamida para o tratamento de traumas da medula espinhal - Google Patents

Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin-4-il)- 5-(metóxi)piridina-2-carboxamida para o tratamento de traumas da medula espinhal

Info

Publication number
BRPI0810446A2
BRPI0810446A2 BRPI0810446-8A2A BRPI0810446A BRPI0810446A2 BR PI0810446 A2 BRPI0810446 A2 BR PI0810446A2 BR PI0810446 A BRPI0810446 A BR PI0810446A BR PI0810446 A2 BRPI0810446 A2 BR PI0810446A2
Authority
BR
Brazil
Prior art keywords
traums
cypropylmetoxy
dicloro
oxidopyridin
carboxamide
Prior art date
Application number
BRPI0810446-8A2A
Other languages
English (en)
Inventor
Philippe Delay-Goyet
Badia Ferzaz
Jocelyne Lolivier
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0810446A2 publication Critical patent/BRPI0810446A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
BRPI0810446-8A2A 2007-04-19 2008-04-16 Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin-4-il)- 5-(metóxi)piridina-2-carboxamida para o tratamento de traumas da medula espinhal BRPI0810446A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0702851A FR2915098B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere
PCT/FR2008/000533 WO2008145840A2 (fr) 2007-04-19 2008-04-16 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1 -oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere

Publications (1)

Publication Number Publication Date
BRPI0810446A2 true BRPI0810446A2 (pt) 2014-10-14

Family

ID=38779706

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810446-8A2A BRPI0810446A2 (pt) 2007-04-19 2008-04-16 Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin-4-il)- 5-(metóxi)piridina-2-carboxamida para o tratamento de traumas da medula espinhal

Country Status (33)

Country Link
US (1) US8592443B2 (pt)
EP (1) EP2150253B1 (pt)
JP (1) JP5386477B2 (pt)
KR (1) KR101470043B1 (pt)
CN (1) CN101674829B (pt)
AR (1) AR066106A1 (pt)
AT (1) ATE503481T1 (pt)
AU (1) AU2008257321B2 (pt)
BR (1) BRPI0810446A2 (pt)
CA (1) CA2684172C (pt)
CL (1) CL2008001134A1 (pt)
CY (1) CY1111779T1 (pt)
DE (1) DE602008005873D1 (pt)
DK (1) DK2150253T3 (pt)
EA (1) EA015355B1 (pt)
ES (1) ES2363056T3 (pt)
FR (1) FR2915098B1 (pt)
HR (1) HRP20110459T1 (pt)
IL (1) IL201451A (pt)
JO (1) JO2662B1 (pt)
MA (1) MA31369B1 (pt)
ME (1) ME00934B (pt)
MX (1) MX2009011285A (pt)
MY (1) MY146657A (pt)
NZ (1) NZ580483A (pt)
PA (1) PA8776601A1 (pt)
PL (1) PL2150253T3 (pt)
PT (1) PT2150253E (pt)
PY (1) PY08013253A (pt)
SI (1) SI2150253T1 (pt)
TW (1) TWI411435B (pt)
UY (1) UY31033A1 (pt)
WO (1) WO2008145840A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2915099B1 (fr) 2007-04-19 2009-06-05 Sanofi Aventis Sa Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes craniens
CN104955808A (zh) * 2012-11-28 2015-09-30 赛诺菲 4-(环丙基甲氧基)-n-(3,5-二氯-1-氧化吡啶-4-基)-5-甲氧基吡啶-2-甲酰胺的晶型的制备方法以及晶型
BR112015012216A2 (pt) * 2012-11-28 2017-07-11 Sanofi Sa processo para a preparação de 4-(ciclopropilmetóxi)-n-(3,5-dicloro-1-óxido-4-piridil)-5-metoxipiridina-2-carboxamida
EP4281065A1 (en) 2021-01-20 2023-11-29 Alto Neuroscience, Inc. Enhancement of camp signaling as a combination drug strategy for the treatment of depression and related conditions
WO2025079694A1 (ja) * 2023-10-12 2025-04-17 株式会社 メドレックス 経皮吸収組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
CA2160928C (en) * 1993-07-28 2005-07-05 Garry Fenton Compounds as pde iv and tnf inhibitors
GB9401460D0 (en) 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
GB9507297D0 (en) 1995-04-07 1995-05-31 Rh Ne Poulenc Rorer Limited New composition of matter
US6196968B1 (en) 1997-06-02 2001-03-06 General Surgical Innovations, Inc. Direct vision subcutaneous tissue retractor and method for use
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
ATE290002T1 (de) * 1999-12-23 2005-03-15 Icos Corp Cyclische amp spezifische phosphodiesterase inhibitoren
JP2005506286A (ja) 2001-03-02 2005-03-03 ブリストル−マイヤーズ　スクイブ　カンパニー サイクリック−ａｍｐ関連疾患の治療を目的としたメラノコルチン受容体アゴニストおよびホスホジエステラーゼ阻害剤の併用投与
EP1519922A1 (en) 2002-07-02 2005-04-06 Merck Frosst Canada & Co. Di-aryl-substituted ethane pyridone pde4 inhibitors
US20060083714A1 (en) 2003-01-27 2006-04-20 Warner James M Combination of a pde iv inhibitor and a tnf-alpha antagonist
JP2007525482A (ja) * 2003-10-07 2007-09-06 レノビス， インコーポレイテッド イオンチャネルリガンドとしてのアミド化合物およびその使用
WO2006135828A2 (en) * 2005-06-10 2006-12-21 Memory Pharmaceuticals Corporation Trisubstituted amines as phosphodiesterase 4 inhibitors
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
AU2008257321B2 (en) 2013-08-15
EA015355B1 (ru) 2011-06-30
EP2150253A2 (fr) 2010-02-10
PL2150253T3 (pl) 2011-08-31
ME00934B (me) 2012-06-20
CY1111779T1 (el) 2015-10-07
MY146657A (en) 2012-09-14
CN101674829B (zh) 2012-01-18
JP2010524905A (ja) 2010-07-22
CA2684172A1 (fr) 2008-12-04
UY31033A1 (es) 2008-11-28
WO2008145840A3 (fr) 2009-06-25
SI2150253T1 (sl) 2011-07-29
JO2662B1 (en) 2012-06-17
PT2150253E (pt) 2011-06-17
TWI411435B (zh) 2013-10-11
AU2008257321A1 (en) 2008-12-04
IL201451A0 (en) 2010-05-31
JP5386477B2 (ja) 2014-01-15
CL2008001134A1 (es) 2009-01-16
CA2684172C (fr) 2015-10-27
ES2363056T3 (es) 2011-07-19
DE602008005873D1 (de) 2011-05-12
WO2008145840A2 (fr) 2008-12-04
MA31369B1 (fr) 2010-05-03
FR2915098B1 (fr) 2009-06-05
EP2150253B1 (fr) 2011-03-30
HK1142000A1 (en) 2010-11-26
DK2150253T3 (da) 2011-07-25
KR20090130063A (ko) 2009-12-17
PA8776601A1 (es) 2008-11-19
EA200970969A1 (ru) 2010-02-26
NZ580483A (en) 2011-06-30
KR101470043B1 (ko) 2014-12-05
CN101674829A (zh) 2010-03-17
TW200911248A (en) 2009-03-16
AR066106A1 (es) 2009-07-22
ATE503481T1 (de) 2011-04-15
HRP20110459T1 (hr) 2011-07-31
PY08013253A (es) 2013-08-01
US8592443B2 (en) 2013-11-26
US20100137370A1 (en) 2010-06-03
MX2009011285A (es) 2009-11-02
FR2915098A1 (fr) 2008-10-24
IL201451A (en) 2013-04-30

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]