BRPI0812891A2 - Dispositivo integrado lab-on-a-chip, sistema de diagnóstico integrado lab-on-a-chip, e, método para realizar um processo de extração de ácido nucléico em uma amostra de fluido contendo células e/ou partículas usando um dispositivo integrado lab-on-a-chip. - Google Patents

Dispositivo integrado lab-on-a-chip, sistema de diagnóstico integrado lab-on-a-chip, e, método para realizar um processo de extração de ácido nucléico em uma amostra de fluido contendo células e/ou partículas usando um dispositivo integrado lab-on-a-chip.

Info

Publication number
BRPI0812891A2
BRPI0812891A2 BRPI0812891-0A2A BRPI0812891A BRPI0812891A2 BR PI0812891 A2 BRPI0812891 A2 BR PI0812891A2 BR PI0812891 A BRPI0812891 A BR PI0812891A BR PI0812891 A2 BRPI0812891 A2 BR PI0812891A2
Authority
BR
Brazil
Prior art keywords
lab
chip
chip integrated
partitus
sample
Prior art date
Application number
BRPI0812891-0A2A
Other languages
English (en)
Inventor
Lars A Solli
Anja Gulliksen
Frank Karlsen
Tobias Baier
Rainer Gransee
Thomas Hansen-Hagge
Klaus Stefan Drese
Liv Furuberg
Original Assignee
Norchip As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norchip As filed Critical Norchip As
Publication of BRPI0812891A2 publication Critical patent/BRPI0812891A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0812891-0A2A 2007-06-07 2008-06-09 Dispositivo integrado lab-on-a-chip, sistema de diagnóstico integrado lab-on-a-chip, e, método para realizar um processo de extração de ácido nucléico em uma amostra de fluido contendo células e/ou partículas usando um dispositivo integrado lab-on-a-chip. BRPI0812891A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0710957.2A GB0710957D0 (en) 2007-06-07 2007-06-07 A device for carrying out cell lysis and nucleic acid extraction
PCT/GB2008/001956 WO2008149111A1 (en) 2007-06-07 2008-06-09 A device for carrying out cell lysis and nucleic acid extraction

Publications (1)

Publication Number Publication Date
BRPI0812891A2 true BRPI0812891A2 (pt) 2014-12-09

Family

ID=38318914

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812891-0A2A BRPI0812891A2 (pt) 2007-06-07 2008-06-09 Dispositivo integrado lab-on-a-chip, sistema de diagnóstico integrado lab-on-a-chip, e, método para realizar um processo de extração de ácido nucléico em uma amostra de fluido contendo células e/ou partículas usando um dispositivo integrado lab-on-a-chip.

Country Status (7)

Country Link
US (1) US8404440B2 (pt)
EP (1) EP2160243B1 (pt)
JP (1) JP2010529839A (pt)
CN (1) CN101765463A (pt)
BR (1) BRPI0812891A2 (pt)
GB (1) GB0710957D0 (pt)
WO (1) WO2008149111A1 (pt)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877507B2 (en) * 2007-04-06 2014-11-04 Qiagen Gaithersburg, Inc. Ensuring sample adequacy using turbidity light scattering techniques
EP2310126A1 (en) * 2008-06-27 2011-04-20 Toxispot A/S Cartridge and system for liquid handling automation
DE102009000529A1 (de) * 2009-01-30 2010-08-19 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikrofluidischer Chip mit Druckmesseinrichtung
GB0912509D0 (en) 2009-07-17 2009-08-26 Norchip As A microfabricated device for metering an analyte
DE102009045405A1 (de) * 2009-10-06 2011-04-14 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikrofluidische Struktur und Verfahren zum Positionieren eines Flüssigkeitsvolumens in einem mikrofluidischen System
ITTO20100865A1 (it) * 2010-10-29 2012-04-30 Matteo Cocuzza Purificazione ed amplificazione di acidi nucleici in un dispositivo microfluidico comprendente superfici di polidimetilsilossano
EP2556887A1 (en) * 2011-08-08 2013-02-13 SAW instruments GmbH Improved microfluidic devices useful for selective exposure of one or more sample liquids to one or more sample regions
US20130074944A1 (en) * 2011-09-26 2013-03-28 Integenx Inc. Methods and Apparatuses for Releasably Fastening Pins
FR2981283B1 (fr) * 2011-10-13 2014-08-29 Chambre De Commerce Et De L Ind De Paris Au Titre De Son Etablissement D Enseignement Superieur Esie Dispositif microfluidique pour analyser un fluide sous pression.
KR101915675B1 (ko) 2012-02-07 2018-11-06 주식회사 미코바이오메드 초고속 핵산 추출 장치, 및 이를 이용하는 핵산 추출 방법
ITTO20120320A1 (it) * 2012-04-12 2013-10-13 St Microelectronics Srl Dispositivo e metodo per la preparazione di campioni biologici, in particolare per l'estrazione del dna, e il caricamento in pozzetti per la successiva esecuzione della pcr
NZ704075A (en) 2012-06-28 2016-07-29 Fluoresentric Inc A chemical indicator device
US9399986B2 (en) * 2012-07-31 2016-07-26 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
US20150259671A1 (en) * 2012-07-31 2015-09-17 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
WO2014047523A2 (en) 2012-09-21 2014-03-27 California Institute Of Technology Methods and devices for sample lysis
US9957553B2 (en) 2012-10-24 2018-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
CN107866286A (zh) 2013-03-15 2018-04-03 金马克诊断股份有限公司 用于操纵可变形流体容器的系统、方法和设备
US10436680B2 (en) 2013-10-15 2019-10-08 Kianoosh Peyvan Capture, disruption, and extraction apparatus and method
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
CN103952287B (zh) * 2014-03-13 2016-01-13 中国航天员科研训练中心 基于fta卡的微流控的核酸提取装置及方法
WO2016031844A1 (ja) 2014-08-29 2016-03-03 日本電気株式会社 マイクロチップ、マイクロチップ制御装置及びマイクロチップ制御システム
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
CN105734045B (zh) * 2014-12-11 2019-02-01 中国科学院大连化学物理研究所 一种基于微流控芯片的快速多通量提取血液样本dna的方法
CN105733923B (zh) * 2014-12-11 2018-06-19 中国科学院大连化学物理研究所 一种微流控芯片及利用微流控芯片的核酸提取纯化方法
CN104560636A (zh) * 2014-12-30 2015-04-29 北京理工大学 一种细胞预处理装置和方法
US9623415B2 (en) 2014-12-31 2017-04-18 Click Diagnostics, Inc. Devices and methods for molecular diagnostic testing
US11207681B2 (en) 2015-07-17 2021-12-28 Delta Electronics, Inc. Method for extracting nucleic acid and extraction cassette thereof
US11491482B2 (en) 2015-07-17 2022-11-08 Delta Electronics, Inc. Method for extracting nucleic acid and extraction cassette thereof
TWI591182B (zh) 2015-07-17 2017-07-11 台達電子工業股份有限公司 核酸萃取裝置
CN109966776B (zh) * 2017-12-26 2021-07-13 台达电子工业股份有限公司 核酸萃取方法及其萃取卡匣
EP3402595A4 (en) * 2016-01-11 2019-10-02 Fluoresentric, Inc. SYSTEMS, DEVICES AND METHOD FOR INLINE SAMPLE PREPARATION
CN105482988B (zh) * 2016-01-14 2017-12-08 西安交通大学 一种纸基全自动核酸提取装置及制备方法
US9775339B1 (en) 2016-04-05 2017-10-03 International Business Machines Corporation Lateral silicon nanospikes fabricated using metal-assisted chemical etching
WO2017177391A1 (en) * 2016-04-13 2017-10-19 Shenzhen Genorivision Technology Co. Ltd. A multi-functional microfluidics device for biological sample screening
US10696939B2 (en) * 2016-04-22 2020-06-30 Hewlett-Packard Development Company, L.P. Cell lysis
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) * 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
EP3478857A1 (en) 2016-06-29 2019-05-08 Click Diagnostics, Inc. Devices and methods for the detection of molecules using a flow cell
US20210370299A1 (en) * 2016-09-23 2021-12-02 Archerdx, Llc Thermal assemblies for nucleic acid preparation
DE102016222032A1 (de) * 2016-11-10 2018-05-17 Robert Bosch Gmbh Mikrofluidische Vorrichtung und Verfahren zur Analyse von Nukleinsäuren
CN107090403B (zh) * 2017-03-22 2019-06-18 清华大学 一种细胞裂解系统和方法
EP3611508B1 (en) * 2017-05-16 2022-08-03 SK Telecom Co., Ltd. Nucleic acid analysis apparatus using catridge
MX2020004783A (es) 2017-11-09 2020-08-13 Visby Medical Inc Dispositivo portatil para el diagnostico molecular y metodos para la deteccion de virus objetivo.
WO2020028559A1 (en) 2018-07-31 2020-02-06 University Of Florida Research Foundation Apparatus and method for performing microorganism detection
CN108949507A (zh) * 2018-08-21 2018-12-07 苏州德思普生物科技有限公司 一种提取人类全血中细菌总核酸的微流控芯片
JP2021534804A (ja) 2018-09-03 2021-12-16 ビスビュー メディカル，インコーポレイテッド 抗生物質感受性検査のための装置および方法
CN109355283B (zh) * 2018-11-27 2023-05-05 中国科学院上海技术物理研究所 一种适用于空间的核酸自动提取装置
WO2020159545A1 (en) 2019-02-01 2020-08-06 Hewlett-Packard Development Company, L.P. Chemical lysis systems
US10820847B1 (en) 2019-08-15 2020-11-03 Talis Biomedical Corporation Diagnostic system
CN110862907B (zh) * 2019-12-06 2021-10-08 中国科学院长春光学精密机械与物理研究所 一种核酸提取预处理扩增系统
CN110885749A (zh) * 2019-12-09 2020-03-17 西人马联合测控（泉州）科技有限公司 病毒检测系统及其微流控芯片
EP4085149A4 (en) 2020-01-03 2024-03-06 Visby Medical, Inc. Devices and methods for antibiotic susceptibility testing
CN111334406A (zh) * 2020-03-05 2020-06-26 纽奥维特(成都)生物科技有限公司 一种新型核酸推进式提取纯化仪
CN111440703A (zh) * 2020-05-19 2020-07-24 广州高盛生物科技股份有限公司 一种双提取模式核酸提取工作站及核酸提取方法
CN115703993B (zh) * 2021-08-17 2025-08-01 北京京东方技术开发有限公司 微流控芯片、其核酸提取方法及核酸提取装置
EP4405457A4 (en) * 2021-09-26 2026-01-07 John Richard Nobile AUTOMATED APPARATUS AND METHOD FOR SAMPLE EXTRACTION
CN114480083A (zh) * 2021-12-21 2022-05-13 序康医疗科技（苏州）有限公司 一种微流控样本保存芯片及胚胎活检细胞处理方法
CN118406547A (zh) * 2024-05-17 2024-07-30 壹宏(深圳)基因有限公司 一种全自动粪便核酸提取卡盒及其提取核酸的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403367B1 (en) 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US6664104B2 (en) * 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
FR2813207B1 (fr) * 2000-08-28 2002-10-11 Bio Merieux Carte reactionnelle et utilisation d'une telle carte
GB2368809B (en) 2000-09-15 2004-09-29 Norchip As Microfabricated reaction chamber system
US20030138819A1 (en) * 2001-10-26 2003-07-24 Haiqing Gong Method for detecting disease
WO2003060157A2 (en) 2001-12-28 2003-07-24 Norchip As Fluid manipulation in a microfabricated reaction chamber system
AU2003254093A1 (en) 2002-07-19 2004-02-09 Isis Pharmaceuticals, Inc. Methods for mass spectrometry analysis utilizing an integrated microfluidics sample platform
JP5695287B2 (ja) * 2002-10-02 2015-04-01 カリフォルニア インスティテュート オブ テクノロジー 微小流体の核酸解析
GB2394912B (en) 2002-11-01 2006-07-12 Norchip As A microfabricated fluidic device for fragmentation
US7338637B2 (en) * 2003-01-31 2008-03-04 Hewlett-Packard Development Company, L.P. Microfluidic device with thin-film electronic devices
US20050142565A1 (en) * 2003-12-30 2005-06-30 Agency For Science, Technology And Research Nucleic acid purification chip
GB2416030B (en) * 2004-01-28 2008-07-23 Norchip As A diagnostic system for carrying out a nucleic acid sequence amplification and detection process
CA2607661C (en) * 2005-05-09 2017-08-08 Idaho Technology, Inc. A device and method for two-stage nucleic acid amplification
CN101568636A (zh) * 2006-11-02 2009-10-28 威腾技术公司 用于诊断性检测的模块

Also Published As

Publication number Publication date
EP2160243A1 (en) 2010-03-10
GB0710957D0 (en) 2007-07-18
WO2008149111A1 (en) 2008-12-11
JP2010529839A (ja) 2010-09-02
US20100297754A1 (en) 2010-11-25
CN101765463A (zh) 2010-06-30
US8404440B2 (en) 2013-03-26
EP2160243B1 (en) 2014-09-03

Similar Documents

Publication Publication Date Title
BRPI0916650A2 (pt) dispositivo, processo e sistema para capturar partículas biológicas em suspensão em um meio líquido, processo para realizar uma preparação citológica, e, plataforma de múltiplos testes
WO2010130762A9 (en) Apparatus for and method of automated processing of biological samples
BRPI0820799A2 (pt) Método e sistema para misturar um fluido de tratamento de poço em emulsão
BRPI0814087A2 (pt) Dispositivo biossensor, processo para manufaturar um dispositivo biossensor, e método para detectar a presença de um analito em um fluido de amostra
PL3178559T3 (pl) Zintegrowane urządzenie do wykonywania ekstrakcji kwasu nukleinowego i badań diagnostycznych na wielu próbkach biologicznych
BRPI0922731A2 (pt) Sistema automatizado de lise de micro-organismos presentes em uma amostra, de extração e de purificação dos ácidos nucleicos desses micro-organismos para fins de análises.
BRPI1014955A2 (pt) aparelho para detectar uma substãncia de interesse em um fluido de poço em um poço, e método para detectar uma substância de interesse em um fluido de poço.
CL2011002228A1 (es) Aparato para el analisis integrado de acidos nucleicos en tiempo real, y metodo de detecicion de dichas moleculas.
BRPI0821228A2 (pt) Sistema de modelagem clínica, método para avaliar cenários clínicos hipotéticos, e, processador ou meio legível por computador
WO2008002882A3 (en) Device and method for extraction and analysis of nucleic acids from biological samples
WO2009140326A3 (en) Microfluidic isolation of tumor cells or other rare cells from whole blood or other liquids
BRPI1009874A2 (pt) sistema e método de determinação da concentração de analito em amostra de fluido e biossensor
BRPI0918412A2 (pt) sistema de análise de fluido e método para a operação de um sistema de análise
BR112012018853A2 (pt) dispositivo microfluídico centrífugo, e método para analisar um analito numa amostra líquida
WO2008097559A3 (en) Manipulation of fluids and reactions in microfluidic systems
EP2297586A4 (en) CARTRIDGES WITH A REAGENT, MICROFLUIDIC DEVICE WITH THE CARTRIDGE, METHOD FOR PRODUCING THE MICROFLUIDIC DEVICE, AND METHOD FOR BIOCHEMICAL ANALYZES WITH THE MICROFLUIDIC DEVICE
BRPI0906665A2 (pt) Sistema para detecção de um analito em um fluido corpóreo
BRPI0818877A2 (pt) Método e sistema para análise semi-quantitativa ou quantitativa de ensaios
BR112014032304A2 (pt) método, sistema e ensaio tipo sanduíche para a determinação quantitativa ou qualitativa de um componente alvo em uma amostra líquida, kit para preparar uma amostra líquida, e, dispositivo microfluídico.
EP2463660A4 (en) NUCLEIC ACID ELEMENT FOR USE IN ANALYSIS AND ANALYSIS METHOD, ANALYSIS AGENT AND ANALYSIS INSTRUMENT THEREWITH
BR112014027217A2 (pt) canal, dispositivo de análise microfluídica, processo para a dispensa de um fluido e método para a coleta e entrega de uma amostra de sangue em um dispositivo de análise microfluídica
EP4707798A3 (en) Nanopore arrays
BRPI0818423A2 (pt) Sistema, método, e, mídia legível por computador
BRPI0921976A2 (pt) sistema para coletar fluido em um furo de poço, e método.
BRPI1006973A2 (pt) "sistema para prever fluxo de fluido em um reservatório subterrâneo, e, método implementado por computador."

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]