BRPI0813356A2 - Inibidores de proteína quinase e métodos para uso dos mesmos - Google Patents
Inibidores de proteína quinase e métodos para uso dos mesmosInfo
- Publication number
- BRPI0813356A2 BRPI0813356A2 BRPI0813356-5A2A BRPI0813356A BRPI0813356A2 BR PI0813356 A2 BRPI0813356 A2 BR PI0813356A2 BR PI0813356 A BRPI0813356 A BR PI0813356A BR PI0813356 A2 BRPI0813356 A2 BR PI0813356A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- protein kinase
- kinase inhibitors
- same use
- same
- Prior art date
Links
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94445707P | 2007-06-15 | 2007-06-15 | |
| PCT/US2008/066426 WO2008157131A1 (en) | 2007-06-15 | 2008-06-10 | Protein kinase inhibitors and methods for using thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0813356A2 true BRPI0813356A2 (pt) | 2014-12-30 |
Family
ID=39672881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0813356-5A2A BRPI0813356A2 (pt) | 2007-06-15 | 2008-06-10 | Inibidores de proteína quinase e métodos para uso dos mesmos |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20100184765A1 (pt) |
| EP (1) | EP2170867A1 (pt) |
| JP (1) | JP2010529990A (pt) |
| KR (1) | KR20100021452A (pt) |
| CN (1) | CN101707863A (pt) |
| AU (1) | AU2008266290A1 (pt) |
| BR (1) | BRPI0813356A2 (pt) |
| CA (1) | CA2690653A1 (pt) |
| EA (1) | EA200901654A1 (pt) |
| MX (1) | MX2009013782A (pt) |
| WO (1) | WO2008157131A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7297800B2 (en) * | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
| US7884119B2 (en) | 2005-09-07 | 2011-02-08 | Rigel Pharmaceuticals, Inc. | Triazole derivatives useful as Axl inhibitors |
| WO2008083353A1 (en) | 2006-12-29 | 2008-07-10 | Rigel Pharmaceuticals, Inc. | Bicyclic aryl and bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| US8012965B2 (en) | 2006-12-29 | 2011-09-06 | Rigel Pharmaceuticals, Inc. | Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| EP2078010B1 (en) | 2006-12-29 | 2014-01-29 | Rigel Pharmaceuticals, Inc. | Polycyclic heteroaryl substituted triazoles useful as axl inhibitors |
| JP2010514810A (ja) | 2006-12-29 | 2010-05-06 | ライジェル ファーマシューティカルズ， インコーポレイテッド | Ａｘｌインヒビターとして有用な置換トリアゾール |
| CA2710046C (en) | 2006-12-29 | 2016-02-09 | Rigel Pharmaceuticals, Inc. | N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as axl inhibitors |
| EP2205592B1 (en) | 2007-10-26 | 2013-05-08 | Rigel Pharmaceuticals, Inc. | Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as axl inhibitors |
| CA2716947A1 (en) * | 2008-02-29 | 2009-09-11 | Array Biopharma Inc. | Imidazo [4,5-b] pyridine derivatives used as raf inhibitors |
| JP2011513331A (ja) * | 2008-02-29 | 2011-04-28 | アレイ バイオファーマ、インコーポレイテッド | ピラゾール［３，４−ｂ］ピリジンＲＡＦ阻害剤 |
| JP2011513332A (ja) * | 2008-02-29 | 2011-04-28 | アレイ バイオファーマ、インコーポレイテッド | 癌の治療のためのｒａｆ阻害剤としてのｎ−（６−アミノピリジン−３−イル）−３−（スルホンアミド）ベンズアミド誘導体 |
| KR20100122505A (ko) * | 2008-02-29 | 2010-11-22 | 어레이 바이오파마 인크. | Ｒａｆ 저해물질 화합물 및 이들의 이용 방법 |
| ES2537480T3 (es) | 2008-07-09 | 2015-06-08 | Rigel Pharmaceuticals, Inc. | Triazoles sustituidos con heteroarilo policíclicos útiles como inhibidores de Axl |
| JP5613156B2 (ja) | 2008-07-09 | 2014-10-22 | ライジェル ファーマシューティカルズ， インコーポレイテッド | Ａｘｌ阻害剤として有用な架橋二環ヘテロアリール置換トリアゾール |
| PL2387395T3 (pl) | 2009-01-16 | 2015-03-31 | Rigel Pharmaceuticals Inc | Inhibitory Axl do zastosowania w terapii skojarzonej do zapobiegania, leczenia lub postępowania z nowotworem przerzutowym |
| US10155936B2 (en) | 2014-12-05 | 2018-12-18 | An2H Discovery Limited | Parkin ligase activation methods and compositions |
| EP3070084A1 (en) * | 2015-03-18 | 2016-09-21 | Rottapharm Biotech S.r.l. | New fyn kinase inhibitors |
| WO2016164754A1 (en) * | 2015-04-09 | 2016-10-13 | Eisai R&D Management Co., Ltd. | Fgfr4 inhibitors |
| CN106397432B (zh) * | 2015-08-03 | 2018-03-16 | 南昌弘益科技有限公司 | 作为jak抑制剂的一类化合物 |
| US11319299B2 (en) | 2016-03-01 | 2022-05-03 | Propellon Therapeutics Inc. | Substituted carboxamides as inhibitors of WDR5 protein-protein binding |
| JP2019507179A (ja) | 2016-03-01 | 2019-03-14 | プロペロン セラピューティックス インコーポレイテッド | Ｗｄｒ５タンパク質−タンパク質結合の阻害剤 |
| US10308617B2 (en) | 2016-06-03 | 2019-06-04 | An2H Discovery Limited | Triazole benzamide derivatives and the compositions and methods of treatment regarding the same |
| US10889553B2 (en) | 2017-12-01 | 2021-01-12 | Nysnobio Ireland Dac | Asymmetric triazole benzamide derivatives and the compositions and methods of treatment regarding the same |
| US11649218B2 (en) | 2018-03-09 | 2023-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same |
| WO2021115560A1 (en) | 2019-12-09 | 2021-06-17 | Rottapharm Biotech S.R.L. | New fyn and vegfr2 kinase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI335913B (en) * | 2002-11-15 | 2011-01-11 | Vertex Pharma | Diaminotriazoles useful as inhibitors of protein kinases |
| CN101039933B (zh) * | 2004-09-17 | 2012-06-06 | 沃泰克斯药物股份有限公司 | 可用作蛋白激酶抑制剂的二氨基三唑化合物 |
-
2008
- 2008-06-10 BR BRPI0813356-5A2A patent/BRPI0813356A2/pt not_active Application Discontinuation
- 2008-06-10 KR KR1020097026017A patent/KR20100021452A/ko not_active Withdrawn
- 2008-06-10 EP EP08770592A patent/EP2170867A1/en not_active Withdrawn
- 2008-06-10 MX MX2009013782A patent/MX2009013782A/es not_active Application Discontinuation
- 2008-06-10 WO PCT/US2008/066426 patent/WO2008157131A1/en not_active Ceased
- 2008-06-10 AU AU2008266290A patent/AU2008266290A1/en not_active Abandoned
- 2008-06-10 CA CA2690653A patent/CA2690653A1/en not_active Abandoned
- 2008-06-10 JP JP2010512299A patent/JP2010529990A/ja active Pending
- 2008-06-10 CN CN200880020320A patent/CN101707863A/zh active Pending
- 2008-06-10 US US12/664,765 patent/US20100184765A1/en not_active Abandoned
- 2008-06-10 EA EA200901654A patent/EA200901654A1/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009013782A (es) | 2010-02-01 |
| US20100184765A1 (en) | 2010-07-22 |
| CA2690653A1 (en) | 2008-12-24 |
| AU2008266290A1 (en) | 2008-12-24 |
| EA200901654A1 (ru) | 2010-06-30 |
| CN101707863A (zh) | 2010-05-12 |
| EP2170867A1 (en) | 2010-04-07 |
| KR20100021452A (ko) | 2010-02-24 |
| JP2010529990A (ja) | 2010-09-02 |
| WO2008157131A1 (en) | 2008-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |