BRPI0813404A2 - Derivados de uréia e carbamato como inibidores de transcriptase reversa de não-nucleosídeo - Google Patents
Derivados de uréia e carbamato como inibidores de transcriptase reversa de não-nucleosídeoInfo
- Publication number
- BRPI0813404A2 BRPI0813404A2 BRPI0813404-9A2A BRPI0813404A BRPI0813404A2 BR PI0813404 A2 BRPI0813404 A2 BR PI0813404A2 BR PI0813404 A BRPI0813404 A BR PI0813404A BR PI0813404 A2 BRPI0813404 A2 BR PI0813404A2
- Authority
- BR
- Brazil
- Prior art keywords
- urea
- reverse transcriptase
- transcriptase inhibitors
- nucleoside reverse
- carbamate derivatives
- Prior art date
Links
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- 229940042402 non-nucleoside reverse transcriptase inhibitor Drugs 0.000 title 1
- 239000002726 nonnucleoside reverse transcriptase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93695607P | 2007-06-22 | 2007-06-22 | |
| PCT/EP2008/057391 WO2009000663A1 (en) | 2007-06-22 | 2008-06-12 | Urea and carbamate derivatives as non-nucleoside reverse transcriptase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0813404A2 true BRPI0813404A2 (pt) | 2014-12-30 |
Family
ID=39811644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0813404-9A2A BRPI0813404A2 (pt) | 2007-06-22 | 2008-06-12 | Derivados de uréia e carbamato como inibidores de transcriptase reversa de não-nucleosídeo |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7947709B2 (pt) |
| EP (1) | EP2170836A1 (pt) |
| JP (1) | JP2010530863A (pt) |
| KR (1) | KR20100039348A (pt) |
| CN (1) | CN101784529A (pt) |
| AR (1) | AR067076A1 (pt) |
| AU (1) | AU2008267895A1 (pt) |
| BR (1) | BRPI0813404A2 (pt) |
| CA (1) | CA2692182A1 (pt) |
| CL (1) | CL2008001819A1 (pt) |
| IL (1) | IL202737A0 (pt) |
| MX (1) | MX2009013865A (pt) |
| PE (1) | PE20090419A1 (pt) |
| TW (1) | TW200911804A (pt) |
| WO (1) | WO2009000663A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101679294B (zh) * | 2007-05-30 | 2012-08-08 | 弗·哈夫曼-拉罗切有限公司 | 非核苷逆转录酶抑制剂 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0016787D0 (en) | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
| AU2002242926B2 (en) | 2001-04-10 | 2007-10-11 | Pfizer Inc. | Pyrazole derivatives for treating HIV |
| GB0113524D0 (en) | 2001-06-04 | 2001-07-25 | Hoffmann La Roche | Pyrazole derivatives |
| EP1556381B1 (en) | 2002-09-26 | 2008-02-20 | Pfizer Limited | Pyrazole amides for treating hiv infections |
| MXPA05003195A (es) | 2002-09-26 | 2005-06-08 | Pfizer | Derivados de pirazol como inhibidores de la transcriptasa inversa. |
| GB0223232D0 (en) | 2002-10-07 | 2002-11-13 | Pfizer Ltd | Chemical compounds |
| EP1608629A1 (en) | 2003-03-24 | 2005-12-28 | F. Hoffmann-La Roche Ag | Benzyl-pyridazinons as reverse transcriptase inhibitors |
| TW200505441A (en) | 2003-03-24 | 2005-02-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitorsⅠ |
| CA2559552A1 (en) | 2004-03-23 | 2005-09-29 | F. Hoffmann-La Roche Ag | Benzyl-pyridazinone derivatives as non-nucleoside reverse transcriptase inhibitors |
| US7625949B2 (en) | 2004-04-23 | 2009-12-01 | Roche Palo Alto Llc | Methods for treating retroviral infections |
| US7166738B2 (en) | 2004-04-23 | 2007-01-23 | Roche Palo Alto Llc | Non-nucleoside reverse transcriptase inhibitors |
| SG148179A1 (en) | 2004-07-27 | 2008-12-31 | Hoffmann La Roche | Benzyltriazolone compounds as non-nucleoside reverse transcriptase inhibitors |
| SE0401971D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Piperidne derivatives |
| CA2577144C (en) | 2004-09-30 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Alkynyl compounds as non-nucleoside reverse transcriptase inhibitors |
| EP1831157A2 (en) | 2004-12-22 | 2007-09-12 | Pfizer Limited | Nonnucleoside inhibitors of hiv-1 reverse transcriptase |
| EP1863777A1 (en) | 2005-03-24 | 2007-12-12 | F.Hoffmann-La Roche Ag | 1,2,4 -triazole-5-one compounds as heterocyclic reverse transcriptase inhibitors |
| AR057455A1 (es) * | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
| JP2009510013A (ja) | 2005-09-30 | 2009-03-12 | エフ．ホフマン−ラ ロシュ アーゲー | Ｎｎｒｔ阻害剤 |
| ES2320042T3 (es) | 2005-10-19 | 2009-05-18 | F. Hoffmann-La Roche Ag | Inhibidores de transcriptasa reversa con nucleosidos de n-fenil fenilacetamida. |
| BRPI0617720A2 (pt) | 2005-10-19 | 2011-08-02 | Hoffmann La Roche | compostos inibidores de nnrt de fenil-acetamida, usos dos referidos compostos e composição farmacêutica que os contém |
| CL2007002105A1 (es) | 2006-07-21 | 2008-02-22 | Hoffmann La Roche | Compuestos derivados de 2-[3-(3-cianofenoxi)(fenoxi o fenilsulfanil)]-n-fenil acetamida, inhibidores de la transcriptasa inversa del vih; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar u |
-
2008
- 2008-06-12 BR BRPI0813404-9A2A patent/BRPI0813404A2/pt not_active Application Discontinuation
- 2008-06-12 EP EP08760931A patent/EP2170836A1/en not_active Withdrawn
- 2008-06-12 CA CA002692182A patent/CA2692182A1/en not_active Abandoned
- 2008-06-12 KR KR1020107001424A patent/KR20100039348A/ko not_active Withdrawn
- 2008-06-12 WO PCT/EP2008/057391 patent/WO2009000663A1/en not_active Ceased
- 2008-06-12 AU AU2008267895A patent/AU2008267895A1/en not_active Abandoned
- 2008-06-12 CN CN200880103679A patent/CN101784529A/zh active Pending
- 2008-06-12 JP JP2010512650A patent/JP2010530863A/ja active Pending
- 2008-06-12 MX MX2009013865A patent/MX2009013865A/es not_active Application Discontinuation
- 2008-06-19 CL CL2008001819A patent/CL2008001819A1/es unknown
- 2008-06-19 TW TW097122908A patent/TW200911804A/zh unknown
- 2008-06-20 AR ARP080102629A patent/AR067076A1/es unknown
- 2008-06-20 PE PE2008001059A patent/PE20090419A1/es not_active Application Discontinuation
- 2008-06-20 US US12/214,651 patent/US7947709B2/en not_active Expired - Fee Related
-
2009
- 2009-12-15 IL IL202737A patent/IL202737A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009000663A1 (en) | 2008-12-31 |
| AU2008267895A1 (en) | 2008-12-31 |
| CA2692182A1 (en) | 2008-12-31 |
| JP2010530863A (ja) | 2010-09-16 |
| MX2009013865A (es) | 2010-01-27 |
| CL2008001819A1 (es) | 2009-05-22 |
| TW200911804A (en) | 2009-03-16 |
| US20090012034A1 (en) | 2009-01-08 |
| US7947709B2 (en) | 2011-05-24 |
| PE20090419A1 (es) | 2009-04-18 |
| KR20100039348A (ko) | 2010-04-15 |
| CN101784529A (zh) | 2010-07-21 |
| EP2170836A1 (en) | 2010-04-07 |
| IL202737A0 (en) | 2010-06-30 |
| AR067076A1 (es) | 2009-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |