CR20130360A - Compuesto heterocíclico y su uso - Google Patents

Compuesto heterocíclico y su uso

Info

Publication number: CR20130360A
Authority: CR; Costa Rica
Prior art keywords: heterocyclic compound; heterocyclic; compound
Prior art date: 2008-06-19

Application number

CR20130360A

Other languages

English (en)

Inventor

Takanobu Kuroita

Yasuhiro Imaeda

Kouichi Iwanaga

Naohiro Taya

Hidekazu Tokuhara

Yoshiyuki Fukase

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-19

Filing date

2013-07-24

Publication date

2013-09-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41282529&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20130360(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-07-24 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2013-09-03 Publication of CR20130360A publication Critical patent/CR20130360A/es

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Enzymes And Modification Thereof (AREA)
Hydrogenated Pyridines (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CR20130360A 2008-06-19 2013-07-24 Compuesto heterocíclico y su uso CR20130360A (es)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2008161049		2008-06-19
JP2009004882		2009-01-13
PCT/JP2009/061438 WO2009154300A2 (en)	2008-06-19	2009-06-17	Heterocyclic compound and use thereof

Publications (1)

Publication Number	Publication Date
CR20130360A true CR20130360A (es)	2013-09-03

Family

ID=41282529

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CR20110001A CR20110001A (es)	2008-06-19	2011-01-10	Compuesto heterocíclico y uso del mismo
CR20130360A CR20130360A (es)	2008-06-19	2013-07-24	Compuesto heterocíclico y su uso

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
CR20110001A CR20110001A (es)	2008-06-19	2011-01-10	Compuesto heterocíclico y uso del mismo

Country Status (38)

Country	Link
US (5)	US8466282B2 (es)
EP (1)	EP2297114B1 (es)
JP (3)	JP4800445B2 (es)
KR (2)	KR101578264B1 (es)
CN (2)	CN103373985B (es)
AR (1)	AR072166A1 (es)
AU (1)	AU2009261153B2 (es)
BR (1)	BRPI0914802B8 (es)
CA (1)	CA2728476C (es)
CL (1)	CL2010001361A1 (es)
CO (1)	CO6300862A2 (es)
CR (2)	CR20110001A (es)
CY (1)	CY1120995T1 (es)
DK (1)	DK2297114T3 (es)
DO (2)	DOP2010000381A (es)
EA (2)	EA019755B1 (es)
EC (1)	ECSP11010770A (es)
ES (1)	ES2676289T3 (es)
GE (2)	GEP20166443B (es)
HR (1)	HRP20181370T1 (es)
HU (1)	HUE039416T2 (es)
IL (1)	IL209282A (es)
JO (1)	JO3465B1 (es)
LT (1)	LT2297114T (es)
MA (1)	MA32483B1 (es)
MX (2)	MX2010013602A (es)
MY (1)	MY160771A (es)
NZ (2)	NZ589825A (es)
PE (2)	PE20110067A1 (es)
PL (1)	PL2297114T3 (es)
PT (1)	PT2297114T (es)
RS (1)	RS57591B1 (es)
SG (1)	SG188117A1 (es)
SI (1)	SI2297114T1 (es)
TW (2)	TWI472523B (es)
UY (1)	UY31907A (es)
WO (1)	WO2009154300A2 (es)
ZA (1)	ZA201009073B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5441705B2 (ja)	2007-10-15	2014-03-12	武田薬品工業株式会社	アミド化合物およびその用途
AU2008339351B2 (en)	2007-12-19	2013-02-28	Sumitomo Dainippon Pharma Co., Ltd.	Bicyclic heterocyclic derivative
JO3465B1 (ar)	2008-06-19	2020-07-05	Takeda Pharmaceuticals Co	مركب متغاير الحلقه واستخدامه
US9090601B2 (en)	2009-01-30	2015-07-28	Millennium Pharmaceuticals, Inc.	Thiazole derivatives
JP5331883B2 (ja)	2009-06-24	2013-10-30	大日本住友製薬株式会社	Ｎ−置換−環状アミノ誘導体
WO2011079105A1 (en) *	2009-12-23	2011-06-30	Abbott Laboratories	Novel thienopyrrole compounds
ES2524896T3 (es) *	2010-06-16	2014-12-15	Takeda Pharmaceutical Company Limited	Cristal de compuesto de amida
US8742097B2 (en)	2010-11-09	2014-06-03	Hoffmann-La Roche Inc.	Triazole compounds I
KR20130100348A (ko) *	2010-11-09	2013-09-10	에프. 호프만-라 로슈 아게	Gaba 수용체에 대한 리간드로서의 트라이아졸 유도체
US20120178813A1 (en)	2011-01-12	2012-07-12	Thetis Pharmaceuticals Llc	Lipid-lowering antidiabetic agent
CN104781226A (zh) *	2012-02-14	2015-07-15	陶氏环球技术有限责任公司	非离子型表面活性剂组合物
WO2013122260A1 (en)	2012-02-15	2013-08-22	Takeda Pharmaceutical Company Limited	Tablet
KR20150033679A (ko) *	2012-06-26	2015-04-01	사니오나 에이피에스	페닐 트리아졸 유도체 및 이의 gabaa 수용체 복합체 조절용 용도
US9382187B2 (en)	2012-07-10	2016-07-05	Thetis Pharmaceuticals Llc	Tri-salt form of metformin
US8765811B2 (en)	2012-07-10	2014-07-01	Thetis Pharmaceuticals Llc	Tri-salt form of metformin
WO2015156346A1 (ja) *	2014-04-10	2015-10-15	武田薬品工業株式会社	複素環化合物の製造法
US9505709B2 (en)	2014-05-05	2016-11-29	Thetis Pharmaceuticals Llc	Compositions and methods relating to ionic salts of peptides
US9242008B2 (en)	2014-06-18	2016-01-26	Thetis Pharmaceuticals Llc	Mineral amino-acid complexes of fatty acids
KR20170023061A (ko)	2014-06-18	2017-03-02	테티스 파마수티컬스 엘엘씨	활성제의 미네랄 아미노산 복합체
US10758525B2 (en)	2015-01-22	2020-09-01	MyoKardia, Inc.	4-methylsulfonyl-substituted piperidine urea compounds
CA3026264A1 (en)	2016-06-03	2017-12-07	Thetis Pharmaceuticals Llc	Compositions and methods relating to salts of specialized pro-resolving mediators
CN108727249A (zh) *	2018-07-07	2018-11-02	台州学院	3-二氟甲基哌啶盐酸盐及其衍生物的合成方法
AU2020315605A1 (en)	2019-07-16	2022-03-03	MyoKardia, Inc.	Polymorphic forms of (R)-4-(1-((3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-N-(isoxazol-3-yl)piperidine-1-carboxamide

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL102183A (en)	1991-06-27	1999-11-30	Takeda Chemical Industries Ltd	Biphenyl substituted heterocyclic compounds their production and pharmaceutical compositions comprising them
RU2168510C2 (ru)	1991-07-31	2001-06-10	Такеда Кемикал Индастриз, Лтд.	Гетероциклическое соединение, фармацевтическая композиция, способ антагонизирования ангиотензина ii
IL117659A (en)	1995-04-13	2000-12-06	Dainippon Pharmaceutical Co	Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same
FI974437A0 (fi)	1995-06-06	1997-12-05	Pfizer	Substituoituja N-(indoli-2-karbonyyli)amideja ja johdannaisia glykogeenifosforylaasi-inhibiittoreina
UA58494C2 (uk)	1995-06-07	2003-08-15	Зенека Лімітед	Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
AU717422B2 (en)	1995-09-01	2000-03-23	Eli Lilly And Company	Indolyl neuropeptide Y receptor antagonists
TWI227240B (en)	2000-06-06	2005-02-01	Pfizer	2-aminocarbonyl-9H-purine derivatives
US7199147B2 (en)	2001-06-12	2007-04-03	Dainippon Sumitomo Pharma Co., Ltd.	Rho kinase inhibitors
US20030078278A1 (en)	2001-06-26	2003-04-24	Pfizer Inc.	Spiropiperidine compounds as ligands for ORL-1 receptor
DE60235114D1 (de)	2001-11-01	2010-03-04	Icagen Inc	Pyrazolamide zur anwendung in der behandlung von schmerz
WO2003055482A1 (en)	2001-12-21	2003-07-10	Novo Nordisk A/S	Amide derivatives as gk activators
AU2003249597B2 (en)	2002-03-08	2007-06-28	Merck Sharp & Dohme Corp.	Mitotic kinesin inhibitors
AU2003287057B2 (en)	2002-10-18	2008-08-21	Merck Sharp & Dohme Corp.	Mitotic kinesin inhibitors
US20040204455A1 (en)	2003-04-10	2004-10-14	Cody Wayne Livingston	Piperidine derivative rennin inhibitors
JP2006527770A (ja) *	2003-06-18	2006-12-07	アストラゼネカアクチボラグ	Ｃｂ１モジュレーターとしての２−置換５，６−ジアリール−ピラジン誘導体
EP1664026B1 (en)	2003-08-15	2009-01-21	Merck & Co., Inc.	Mitotic kinesin inhibitors
EP1656146A4 (en)	2003-08-15	2009-04-15	Merck & Co Inc	INHIBITORS OF MITOTIC KINESINE
TW200513461A (en)	2003-10-01	2005-04-16	Speedel Experimenta Ag	Organische verbindungen
CA2545644C (en)	2003-11-12	2011-11-01	Lg Life Sciences Ltd.	Melanocortin receptor agonists
AR053406A1 (es)	2004-07-09	2007-05-09	Speedel Experimenta Ag	Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas
KR20070050076A (ko) *	2004-08-10	2007-05-14	인사이트 산 디에고 인코포레이티드	아미도 화합물 및 약제로서의 이의 용도
JP5067968B2 (ja)	2004-10-07	2012-11-07	ビテファーマシューティカルズ，インコーポレイテッド	ジアミノアルカンアスパラギン酸プロテアーゼ阻害剤
CN101048383A (zh)	2004-11-23	2007-10-03	惠氏公司	促性腺激素释放激素受体拮抗剂
GB0428526D0 (en)	2004-12-30	2005-02-09	Novartis Ag	Organic compounds
CN101137372A (zh)	2005-03-16	2008-03-05	默克公司	有丝分裂驱动蛋白抑制剂
GB0511063D0 (en)	2005-05-31	2005-07-06	Novartis Ag	Organic compounds
GB0514203D0 (en) *	2005-07-11	2005-08-17	Novartis Ag	Organic compounds
EP1932841B1 (en)	2005-08-30	2014-01-01	Asahi Kasei Pharma Corporation	Sulfonamide compound
FI20055498A0 (fi)	2005-09-16	2005-09-16	Biotie Therapies Corp	Sulfonamidijohdannaisia
US7618982B2 (en)	2005-12-19	2009-11-17	Nerviano Medical Sciences S.R.L.	Heteroarylpyrrolopyridinones active as kinase inhibitors
NZ569135A (en) *	2005-12-30	2011-08-26	Novartis Ag	3,5-Substituted piperidine compounds as renin inhibitors
TW200804359A (en)	2006-01-19	2008-01-16	Speedel Experimenta Ag	Substituted 4-phenylpiperidines
US20100121048A1 (en)	2006-02-16	2010-05-13	Takanobu Kuroita	Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension
JP5067364B2 (ja)	2006-03-24	2012-11-07	アステラス製薬株式会社	アシルアミノピペリジン化合物
GB0607954D0 (en)	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
US20090318430A1 (en)	2006-07-21	2009-12-24	Astex Therapeutics Limited	Medical use of cyclin dependent kinases inhibitors
WO2008016666A2 (en) *	2006-08-02	2008-02-07	Cytokinetics, Incorporated	Certain chemical entities, compositions, and methods
US20100056497A1 (en)	2007-01-31	2010-03-04	Dainippon Sumitomo Pharma Co., Ltd	Amide derivative
JP4837701B2 (ja)	2007-04-20	2011-12-14	田辺三菱製薬株式会社	医薬組成物
JP2010163361A (ja) *	2007-04-27	2010-07-29	Dainippon Sumitomo Pharma Co Ltd	キノリン誘導体
WO2008139941A1 (en)	2007-04-27	2008-11-20	Takeda Pharmaceutical Company Limited	Substituted imidazole compound and use thereof
JP2010189275A (ja)	2007-06-14	2010-09-02	Dainippon Sumitomo Pharma Co Ltd	ナフタレン誘導体
TWI452044B (zh)	2007-06-15	2014-09-11	Mitsubishi Tanabe Pharma Corp	嗎啉衍生物
WO2009001915A1 (ja)	2007-06-28	2008-12-31	Takeda Pharmaceutical Company Limited	置換イミダゾール化合物およびその用途
JP2010208947A (ja)	2007-06-29	2010-09-24	Dainippon Sumitomo Pharma Co Ltd	キノロン誘導体
JP2010229034A (ja) *	2007-07-26	2010-10-14	Dainippon Sumitomo Pharma Co Ltd	二環性ピロール誘導体
JP5441705B2 (ja) *	2007-10-15	2014-03-12	武田薬品工業株式会社	アミド化合物およびその用途
JP2011037712A (ja)	2007-12-08	2011-02-24	Dainippon Sumitomo Pharma Co Ltd	４−アリールフェニル誘導体
AU2008339351B2 (en)	2007-12-19	2013-02-28	Sumitomo Dainippon Pharma Co., Ltd.	Bicyclic heterocyclic derivative
AR070454A1 (es)	2008-02-27	2010-04-07	Nycomed Gmbh	Pirrolopirimidincarboxamidas y composiciones farmaceuticas que las comprenden
WO2009112490A1 (en)	2008-03-11	2009-09-17	Cellzome Limited	Sulfonamides as zap-70 inhibitors
JP2009298713A (ja) *	2008-06-11	2009-12-24	Daiichi Sankyo Co Ltd	イミダゾチアゾール誘導体
JO3465B1 (ar) *	2008-06-19	2020-07-05	Takeda Pharmaceuticals Co	مركب متغاير الحلقه واستخدامه
WO2010126002A1 (ja)	2009-04-28	2010-11-04	塩野義製薬株式会社	ヘテロ環スルホンアミド化合物を含有する医薬

2009
- 2009-06-17 JO JOP/2009/0216A patent/JO3465B1/ar active
- 2009-06-17 MX MX2010013602A patent/MX2010013602A/es active IP Right Grant
- 2009-06-17 SI SI200931871T patent/SI2297114T1/sl unknown
- 2009-06-17 AR ARP090102193A patent/AR072166A1/es active IP Right Grant
- 2009-06-17 KR KR1020127014751A patent/KR101578264B1/ko not_active Expired - Fee Related
- 2009-06-17 EA EA201170051A patent/EA019755B1/ru not_active IP Right Cessation
- 2009-06-17 CN CN201310292451.2A patent/CN103373985B/zh not_active Expired - Fee Related
- 2009-06-17 US US12/999,428 patent/US8466282B2/en not_active Expired - Fee Related
- 2009-06-17 WO PCT/JP2009/061438 patent/WO2009154300A2/en not_active Ceased
- 2009-06-17 HU HUE09766748A patent/HUE039416T2/hu unknown
- 2009-06-17 EP EP09766748.9A patent/EP2297114B1/en active Active
- 2009-06-17 US US12/457,646 patent/US8664380B2/en not_active Expired - Fee Related
- 2009-06-17 PE PE2010001164A patent/PE20110067A1/es active IP Right Grant
- 2009-06-17 JP JP2010549957A patent/JP4800445B2/ja not_active Expired - Fee Related
- 2009-06-17 PL PL09766748T patent/PL2297114T3/pl unknown
- 2009-06-17 NZ NZ589825A patent/NZ589825A/xx not_active IP Right Cessation
- 2009-06-17 GE GEAP200913059A patent/GEP20166443B/en unknown
- 2009-06-17 CN CN200980132372.7A patent/CN102123990B/zh active Active
- 2009-06-17 EA EA201301040A patent/EA201301040A1/ru unknown
- 2009-06-17 KR KR1020117001002A patent/KR101207830B1/ko active Active
- 2009-06-17 BR BRPI0914802A patent/BRPI0914802B8/pt not_active IP Right Cessation
- 2009-06-17 MY MYPI2010005939A patent/MY160771A/en unknown
- 2009-06-17 NZ NZ600238A patent/NZ600238A/en not_active IP Right Cessation
- 2009-06-17 AU AU2009261153A patent/AU2009261153B2/en not_active Ceased
- 2009-06-17 LT LTEP09766748.9T patent/LT2297114T/lt unknown
- 2009-06-17 SG SG2013008842A patent/SG188117A1/en unknown
- 2009-06-17 RS RS20180895A patent/RS57591B1/sr unknown
- 2009-06-17 ES ES09766748.9T patent/ES2676289T3/es active Active
- 2009-06-17 CA CA2728476A patent/CA2728476C/en active Active
- 2009-06-17 UY UY0001031907A patent/UY31907A/es not_active Application Discontinuation
- 2009-06-17 PT PT97667489T patent/PT2297114T/pt unknown
- 2009-06-17 PE PE2013001363A patent/PE20140858A1/es not_active Application Discontinuation
- 2009-06-17 GE GEAP200912066A patent/GEP20135957B/en unknown
- 2009-06-17 DK DK09766748.9T patent/DK2297114T3/en active
- 2009-06-17 HR HRP20181370TT patent/HRP20181370T1/hr unknown
- 2009-06-17 TW TW101121074A patent/TWI472523B/zh not_active IP Right Cessation
- 2009-06-17 TW TW098120213A patent/TWI378096B/zh active
2010
- 2010-11-11 IL IL209282A patent/IL209282A/en active IP Right Grant
- 2010-12-06 CL CL2010001361A patent/CL2010001361A1/es unknown
- 2010-12-08 DO DO2010000381A patent/DOP2010000381A/es unknown
- 2010-12-09 MX MX2012014481A patent/MX338557B/es unknown
- 2010-12-17 ZA ZA2010/09073A patent/ZA201009073B/en unknown
2011
- 2011-01-10 CR CR20110001A patent/CR20110001A/es unknown
- 2011-01-14 MA MA33527A patent/MA32483B1/fr unknown
- 2011-01-19 EC EC2011010770A patent/ECSP11010770A/es unknown
- 2011-01-19 CO CO11005108A patent/CO6300862A2/es active IP Right Grant
- 2011-04-08 JP JP2011086570A patent/JP5592831B2/ja not_active Expired - Fee Related
2012
- 2012-04-13 US US13/446,408 patent/US9045436B2/en active Active
2013
- 2013-05-31 DO DO2013000123A patent/DOP2013000123A/es unknown
- 2013-07-24 CR CR20130360A patent/CR20130360A/es unknown
- 2013-12-27 JP JP2013273076A patent/JP5918746B2/ja not_active Expired - Fee Related
2015
- 2015-03-23 US US14/665,237 patent/US9221836B2/en not_active Expired - Fee Related
- 2015-10-28 US US14/925,259 patent/US20160046601A1/en not_active Abandoned
2018
- 2018-09-04 CY CY181100913T patent/CY1120995T1/el unknown

Also Published As

Publication number	Publication date
ES2676289T3 (es)	2018-07-18
IL209282A0 (en)	2011-01-31
ZA201009073B (en)	2012-03-28
SG188117A1 (en)	2013-03-28
PE20110067A1 (es)	2011-02-18
US8466282B2 (en)	2013-06-18
CR20110001A (es)	2013-03-15
EP2297114A2 (en)	2011-03-23
MA32483B1 (fr)	2011-07-03
KR20120084778A (ko)	2012-07-30
MY160771A (en)	2017-03-15
WO2009154300A3 (en)	2010-06-03
JP5592831B2 (ja)	2014-09-17
PE20140858A1 (es)	2014-08-04
JP2014094950A (ja)	2014-05-22
US20110178057A1 (en)	2011-07-21
JP4800445B2 (ja)	2011-10-26
JP2011524853A (ja)	2011-09-08
CL2010001361A1 (es)	2011-07-29
BRPI0914802A2 (pt)	2015-08-11
SI2297114T1 (sl)	2018-10-30
AU2009261153A1 (en)	2009-12-23
DOP2010000381A (es)	2010-12-31
BRPI0914802B1 (pt)	2020-10-27
TW201002685A (en)	2010-01-16
AR072166A1 (es)	2010-08-11
JP2011157391A (ja)	2011-08-18
RS57591B1 (sr)	2018-11-30
IL209282A (en)	2015-07-30
KR101578264B1 (ko)	2015-12-16
EA019755B1 (ru)	2014-06-30
GEP20135957B (en)	2013-11-11
TWI472523B (zh)	2015-02-11
CA2728476C (en)	2017-03-21
HRP20181370T1 (hr)	2018-10-19
CN102123990B (zh)	2014-07-09
CA2728476A1 (en)	2009-12-23
CN102123990A (zh)	2011-07-13
AU2009261153B2 (en)	2014-05-22
US20150191486A1 (en)	2015-07-09
UY31907A (es)	2010-01-29
EA201170051A1 (ru)	2011-08-30
CN103373985A (zh)	2013-10-30
CY1120995T1 (el)	2019-12-11
US8664380B2 (en)	2014-03-04
PT2297114T (pt)	2018-07-26
US9221836B2 (en)	2015-12-29
KR20110019428A (ko)	2011-02-25
WO2009154300A2 (en)	2009-12-23
US20100137587A1 (en)	2010-06-03
DK2297114T3 (en)	2018-07-09
US20120264733A1 (en)	2012-10-18
US20160046601A1 (en)	2016-02-18
JO3465B1 (ar)	2020-07-05
EA201301040A1 (ru)	2014-01-30
BRPI0914802B8 (pt)	2021-05-25
CO6300862A2 (es)	2011-07-21
TWI378096B (en)	2012-12-01
PL2297114T3 (pl)	2018-10-31
NZ600238A (en)	2014-04-30
MX2010013602A (es)	2011-03-15
DOP2013000123A (es)	2013-11-15
ECSP11010770A (es)	2011-02-28
GEP20166443B (en)	2016-03-10
MX338557B (es)	2016-04-21
HUE039416T2 (hu)	2018-12-28
KR101207830B1 (ko)	2012-12-04
JP5918746B2 (ja)	2016-05-18
LT2297114T (lt)	2018-08-10
EP2297114B1 (en)	2018-06-06
CN103373985B (zh)	2015-10-28
TW201240987A (en)	2012-10-16
US9045436B2 (en)	2015-06-02
NZ589825A (en)	2012-11-30

Publication	Publication Date	Title
BRPI1015315A2 (pt)	2018-02-20	composto heterocíclico fundido e uso dos mesmos
BRPI1012533A2 (pt)	2015-09-22	composto de piradazinona e uso do mesmo
DOP2010000260A (es)	2010-10-15	Derivado heterociclico fusionado y su uso
SMT201500218B (it)	2015-10-30	Composti aril-fenil-solfonammido-cicloalchile e loro uso
HRP20190016T1 (hr)	2019-03-08	Heterociklički spojevi i njihova upotreba
BRPI0821668A2 (pt)	2015-06-16	Uso
BRPI0906186A2 (pt)	2015-09-22	composto e uso de um composto
HRP20180718T1 (hr)	2018-07-13	Oligopeptidni spojevi i njihova upotreba
BRPI1007494A2 (pt)	2016-02-16	composto e uso do mesmo
CO6930362A2 (es)	2014-04-28	Compuesto heterocíclico y su uso
BR112012002349A2 (pt)	2015-10-13	composto,e, uso do mesmo
EP2264017A4 (en)	2011-07-27	Heterocyclic derivative and its use
BRPI0907231A2 (pt)	2019-09-24	pirrolpirimidinas e pirrolpiridinas
CR10847A (es)	2009-07-13	Compuesto heteromonociclico y uso del mismo
BRPI0716327A2 (pt)	2014-03-04	Composto de fenilpropionamida e uso
ZA201009073B (en)	2012-03-28	Heterocyclic compound and use thereof
BRPI0906478A2 (pt)	2015-11-24	anticorpo anti-nr10 e uso do mesmo
BRPI0915134A2 (pt)	2016-02-16	composto, e, uso de um composto
BRPI0907365A2 (pt)	2015-07-14	Composição antimicrobiana e uso
BRPI0906705A2 (pt)	2015-06-30	Composto heterocíclicos
HRP20141261T1 (xx)	2015-03-13	Spojevi tioninija i njihove uporabe
BRPI0922344A2 (pt)	2017-10-24	inibidores de tfpi e métodos de uso
BRPI0921044A2 (pt)	2019-09-24	composto heterocíclico de acenafto, composto de inclusão de ciclodextrina do composto heterocíclico de acenafto, complexo de ciclodextrina do composto heterocíclico de acenafto, uso do composto heterocíclico de acenafto, uso do composto de inclusão de ciclodextrina do composto heterocíclico de acenafto e uso do complexo de ciclodextrina
DK2292592T3 (da)	2012-10-08	Sulfonamidforbindelse og anvendelse deraf
CO6781486A2 (es)	2013-10-31	Compuestos y su uso