BRPI0815050A2 - Avidina oxidada com tempo de permanência elevado nos tecidos tratados - Google Patents

Avidina oxidada com tempo de permanência elevado nos tecidos tratados

Info

Publication number: BRPI0815050A2
Authority: BR; Brazil
Prior art keywords: treated tissues; oxidized avidin; permanence time; high permanence; avidin
Prior art date: 2007-08-02

Application number

BRPI0815050-8A2A

Other languages

English (en)

Inventor

Rita De Santis

Carlo Antonio Nuzzolo

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-02

Filing date

2008-07-16

Publication date

2015-02-10

2008-07-16 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

2015-02-10 Publication of BRPI0815050A2 publication Critical patent/BRPI0815050A2/pt

2017-12-26 Publication of BRPI0815050A8 publication Critical patent/BRPI0815050A8/pt

2020-01-28 Publication of BRPI0815050B1 publication Critical patent/BRPI0815050B1/pt

2021-05-25 Publication of BRPI0815050B8 publication Critical patent/BRPI0815050B8/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Neurology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Optics & Photonics (AREA)
Physics & Mathematics (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Inorganic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0815050A 2007-08-02 2008-07-16 avidina oxidada com tempo de permanência elevado em tecidos tratados, complexo compreendendo a referida avidina e uso dos mesmos, composição farmacêutica, kit, bem como processo de oxidação de avidina BRPI0815050B8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP07113733		2007-08-02
EP08157473		2008-06-03
PCT/EP2008/059260 WO2009016031A1 (en)	2007-08-02	2008-07-16	Oxidized avidin with high residency time in the treated tissues

Publications (4)

Publication Number	Publication Date
BRPI0815050A2 true BRPI0815050A2 (pt)	2015-02-10
BRPI0815050A8 BRPI0815050A8 (pt)	2017-12-26
BRPI0815050B1 BRPI0815050B1 (pt)	2020-01-28
BRPI0815050B8 BRPI0815050B8 (pt)	2021-05-25

Family

ID=39734214

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0815050A BRPI0815050B8 (pt)	2007-08-02	2008-07-16	avidina oxidada com tempo de permanência elevado em tecidos tratados, complexo compreendendo a referida avidina e uso dos mesmos, composição farmacêutica, kit, bem como processo de oxidação de avidina

Country Status (25)

Country	Link
US (1)	US8562947B2 (pt)
EP (1)	EP2185203B1 (pt)
JP (1)	JP5577248B2 (pt)
KR (1)	KR101544628B1 (pt)
CN (1)	CN101772353B (pt)
AR (1)	AR067771A1 (pt)
AU (1)	AU2008281901B2 (pt)
BR (1)	BRPI0815050B8 (pt)
CA (1)	CA2694391C (pt)
DK (1)	DK2185203T3 (pt)
EA (1)	EA017017B1 (pt)
ES (1)	ES2625815T3 (pt)
HR (1)	HRP20170735T1 (pt)
HU (1)	HUE032093T2 (pt)
IL (1)	IL203321A (pt)
LT (1)	LT2185203T (pt)
MX (1)	MX2010001302A (pt)
MY (1)	MY155347A (pt)
NZ (1)	NZ582711A (pt)
PL (1)	PL2185203T3 (pt)
PT (1)	PT2185203T (pt)
SG (1)	SG183076A1 (pt)
SI (1)	SI2185203T1 (pt)
TW (1)	TWI441650B (pt)
WO (1)	WO2009016031A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2660320B1 (en) *	2010-12-28	2017-09-27	Japan Tobacco Inc.	Modified tamavidin
JP6019118B2 (ja) *	2011-08-02	2016-11-02	シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−ＴａｕＩｎｄｕｓｔｒｉｅＦａｒｍａｃｅｕｔｉｃｈｅＲｉｕｎｉｔｅＳｏｃｉｅｔａＰｅｒＡｚｉｏｎｉ	吸入に適した酸化型アビジンの医薬品組成物
JP2014001204A (ja) *	2012-05-23	2014-01-09	Kumamoto Univ	腫瘍細胞選択的抗がん剤
JP2016511747A (ja)	2013-01-04	2016-04-21	マサチューセッツインスティテュートオブテクノロジー	ナノ粒子表面結合に基づく薬物の組織への送達
WO2017003908A1 (en)	2015-06-30	2017-01-05	The Trustees Of Columbia University In The City Of New York	Talc-bound compositions and uses thereof
US20200179530A1 (en) *	2016-05-19	2020-06-11	University Of Miami	Targeted delivery of therapeutic agents and imaging reagents to pancreatic cancer cells
JP7245907B2 (ja)	2018-09-25	2023-03-24	シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド	共役分子トラップを使用して、アッセイからビオチン干渉を取り除く方法および組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2178476A1 (en) *	1993-12-07	1995-06-15	Neorx Corporation	Pretargeting methods and compounds
US5716594A (en) *	1994-06-06	1998-02-10	The Jmde Trust	Biotin compounds for targetting tumors and sites of infection
US8021667B2 (en) *	1994-11-16	2011-09-20	Macfarlane Burnet Institute For Medical Research And Public Health Ltd	Compositions for immunotherapy and uses thereof
US6632929B1 (en) *	1998-11-10	2003-10-14	Yeda Research And Development Co. Ltd	Avidin derivatives and uses thereof
US7001994B2 (en) *	2001-01-18	2006-02-21	Genzyme Corporation	Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins
US20040101901A1 (en) *	2002-11-27	2004-05-27	Piotr Tabaczewski	Novel lipophilic complexes for insertion of receptors into lipid membranes
ITRM20030196A1 (it) *	2003-04-24	2004-10-25	Sigma Tau Ind Farmaceuti	Uso di reagenti per la preparazione di un medicamento

2008
- 2008-07-16 EP EP08775109.5A patent/EP2185203B1/en active Active
- 2008-07-16 CN CN2008801016692A patent/CN101772353B/zh not_active Expired - Fee Related
- 2008-07-16 PT PT87751095T patent/PT2185203T/pt unknown
- 2008-07-16 CA CA2694391A patent/CA2694391C/en active Active
- 2008-07-16 HR HRP20170735TT patent/HRP20170735T1/hr unknown
- 2008-07-16 HU HUE08775109A patent/HUE032093T2/en unknown
- 2008-07-16 MY MYPI2010000136A patent/MY155347A/en unknown
- 2008-07-16 JP JP2010518601A patent/JP5577248B2/ja not_active Expired - Fee Related
- 2008-07-16 BR BRPI0815050A patent/BRPI0815050B8/pt not_active IP Right Cessation
- 2008-07-16 ES ES08775109.5T patent/ES2625815T3/es active Active
- 2008-07-16 EA EA201070216A patent/EA017017B1/ru unknown
- 2008-07-16 US US12/670,925 patent/US8562947B2/en active Active
- 2008-07-16 NZ NZ582711A patent/NZ582711A/en not_active IP Right Cessation
- 2008-07-16 LT LTEP08775109.5T patent/LT2185203T/lt unknown
- 2008-07-16 SG SG2012054938A patent/SG183076A1/en unknown
- 2008-07-16 DK DK08775109.5T patent/DK2185203T3/da active
- 2008-07-16 WO PCT/EP2008/059260 patent/WO2009016031A1/en not_active Ceased
- 2008-07-16 PL PL08775109T patent/PL2185203T3/pl unknown
- 2008-07-16 SI SI200831808A patent/SI2185203T1/sl unknown
- 2008-07-16 AU AU2008281901A patent/AU2008281901B2/en not_active Ceased
- 2008-07-16 MX MX2010001302A patent/MX2010001302A/es active IP Right Grant
- 2008-07-16 KR KR1020107004513A patent/KR101544628B1/ko not_active Expired - Fee Related
- 2008-07-18 TW TW097127328A patent/TWI441650B/zh not_active IP Right Cessation
- 2008-08-01 AR ARP080103343A patent/AR067771A1/es active IP Right Grant
2010
- 2010-01-14 IL IL203321A patent/IL203321A/en active IP Right Grant

Also Published As

Publication number	Publication date
LT2185203T (lt)	2017-06-12
ES2625815T3 (es)	2017-07-20
AR067771A1 (es)	2009-10-21
IL203321A (en)	2014-05-28
EA017017B1 (ru)	2012-09-28
DK2185203T3 (da)	2017-06-06
KR20100051696A (ko)	2010-05-17
SI2185203T1 (sl)	2017-07-31
AU2008281901A1 (en)	2009-02-05
WO2009016031A1 (en)	2009-02-05
EP2185203A1 (en)	2010-05-19
HRP20170735T1 (hr)	2017-07-28
BRPI0815050A8 (pt)	2017-12-26
MY155347A (en)	2015-10-15
CA2694391C (en)	2019-02-26
SG183076A1 (en)	2012-08-30
BRPI0815050B1 (pt)	2020-01-28
EA201070216A1 (ru)	2010-08-30
PL2185203T3 (pl)	2017-08-31
JP5577248B2 (ja)	2014-08-20
TWI441650B (zh)	2014-06-21
CN101772353B (zh)	2013-03-06
BRPI0815050B8 (pt)	2021-05-25
AU2008281901B2 (en)	2013-08-15
JP2010535166A (ja)	2010-11-18
EP2185203B1 (en)	2017-02-22
HK1145290A1 (en)	2011-04-15
US8562947B2 (en)	2013-10-22
KR101544628B1 (ko)	2015-08-17
NZ582711A (en)	2011-10-28
MX2010001302A (es)	2010-03-01
US20100239497A1 (en)	2010-09-23
HUE032093T2 (en)	2017-08-28
PT2185203T (pt)	2017-06-02
TW200920403A (en)	2009-05-16
CA2694391A1 (en)	2009-02-05
CN101772353A (zh)	2010-07-07

Legal Events

Date	Code	Title	Description
2017-03-28	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2017-12-26	B25A	Requested transfer of rights approved	Owner name: ALFASIGMA S.P.A. (IT)
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-07-31	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2018-09-04	B06T	Formal requirements before examination [chapter 6.20 patent gazette]
2019-12-10	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2020-01-28	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 28/01/2020, OBSERVADAS AS CONDICOES LEGAIS.
2021-05-25	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/07/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF
2022-02-15	B25G	Requested change of headquarter approved	Owner name: ALFASIGMA S.P.A. (IT)
2025-06-10	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 17A ANUIDADE.
2025-10-07	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2840 DE 10-06-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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