BRPI0815602A2 - Composições de liberação prolongada de trimetazidina e processo para a preparação das mesmas - Google Patents

Composições de liberação prolongada de trimetazidina e processo para a preparação das mesmas

Info

Publication number
BRPI0815602A2
BRPI0815602A2 BRPI0815602-6A2A BRPI0815602A BRPI0815602A2 BR PI0815602 A2 BRPI0815602 A2 BR PI0815602A2 BR PI0815602 A BRPI0815602 A BR PI0815602A BR PI0815602 A2 BRPI0815602 A2 BR PI0815602A2
Authority
BR
Brazil
Prior art keywords
trimethyzidine
preparing
proposed
release compositions
compositions
Prior art date
Application number
BRPI0815602-6A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Deepak Anant Hedge
Sandhya Rajendra Shenoy
Harish Tulsidutt Bhatt
Ashok Omray
Original Assignee
Usv Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Ltd filed Critical Usv Ltd
Publication of BRPI0815602A2 publication Critical patent/BRPI0815602A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0815602-6A2A 2007-08-08 2008-08-07 Composições de liberação prolongada de trimetazidina e processo para a preparação das mesmas BRPI0815602A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1533MU2007 2007-08-08
PCT/IN2008/000493 WO2009066315A2 (fr) 2007-08-08 2008-08-07 Compositions à libération prolongée de trimétazidine et procédé de préparation

Publications (1)

Publication Number Publication Date
BRPI0815602A2 true BRPI0815602A2 (pt) 2015-03-03

Family

ID=40667940

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815602-6A2A BRPI0815602A2 (pt) 2007-08-08 2008-08-07 Composições de liberação prolongada de trimetazidina e processo para a preparação das mesmas

Country Status (3)

Country Link
EP (1) EP2187874A2 (fr)
BR (1) BRPI0815602A2 (fr)
WO (1) WO2009066315A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012515757A (ja) * 2009-01-20 2012-07-12 マイクロ ラブス リミテッド トリメタジジンの放出調節固形薬剤組成物及びその製造方法
TR201001902A2 (tr) * 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Uzatılmış salınımlı trimetazidin tablet
ES2508490T3 (es) * 2010-05-04 2014-10-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulación de trimetazidina con diferentes perfiles de liberación
EP2386302A1 (fr) * 2010-05-11 2011-11-16 Ranbaxy Laboratories Limited Forme pharmaceutique à libération prolongée de trimetazidine et ses procédés de préparation
WO2013180676A1 (fr) * 2012-05-28 2013-12-05 Mahmut Bilgic Nouvelle formulation à libération prolongée
CN105434380A (zh) * 2015-12-11 2016-03-30 南京正科医药股份有限公司 一种盐酸曲美他嗪片
CA3044270A1 (fr) 2016-11-21 2018-05-24 Saghmos Therapeutics, Inc. Utilisation de la trimetazidine dans la prevention et/ou le traitement de l'insuffisance renale aigue induite par contraste
IL283725B2 (en) 2017-06-20 2024-04-01 Imbria Pharmaceuticals Inc Compositions and methods for increasing efficiency of cardiac metabolism
EP3866794B1 (fr) 2018-10-17 2024-12-04 Imbria Pharmaceuticals, Inc. Procédés de traitement de maladies rhumatismales à l'aide de composés à base de trimétazidine
EP3976101A4 (fr) 2019-05-31 2023-06-21 Imbria Pharmaceuticals, Inc. Méthodes de traitement de la fibrose faisant appel à des composés favorisant l'oxydation du glucose
CN110623934B (zh) * 2019-09-26 2022-05-13 杭州百诚医药科技股份有限公司 一种盐酸曲美他嗪缓释片及其制备方法
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
CN111888476A (zh) * 2020-08-17 2020-11-06 深圳市道科思医药有限公司 盐酸曲美他嗪的改良释放药物组合物
CN112315942B (zh) * 2020-11-04 2022-08-09 南京康川济医药科技有限公司 一种盐酸曲美他嗪缓释制剂及其制备方法
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine
WO2025068837A2 (fr) * 2023-09-26 2025-04-03 Zim Laboratories Limited Nouvelle composition pharmaceutique à libération prolongée de trimétazidine ou d'un sel de celle-ci

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE442852T1 (de) * 2000-10-05 2009-10-15 Usv Ltd Trimetazidine enthaltendes arzneimittel mit verzögerter wirkstoffabgabe und verfahren zur herstellung
FR2818549B1 (fr) * 2000-12-26 2003-02-07 Servier Lab Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine
FR2885807B1 (fr) * 2005-05-18 2008-05-16 Mg Pharma Composition pharmaceutique solide a liberation prolongee de 1-(2,3,4-trimethoxybenzyl) piperazine, et procede de preparation

Also Published As

Publication number Publication date
WO2009066315A3 (fr) 2009-09-24
WO2009066315A2 (fr) 2009-05-28
EP2187874A2 (fr) 2010-05-26

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.