BRPI0815698A2 - manipulação de contas em um atuador de gotículas. - Google Patents
manipulação de contas em um atuador de gotículas.Info
- Publication number
- BRPI0815698A2 BRPI0815698A2 BRPI0815698A BRPI0815698A BRPI0815698A2 BR PI0815698 A2 BRPI0815698 A2 BR PI0815698A2 BR PI0815698 A BRPI0815698 A BR PI0815698A BR PI0815698 A BRPI0815698 A BR PI0815698A BR PI0815698 A2 BRPI0815698 A2 BR PI0815698A2
- Authority
- BR
- Brazil
- Prior art keywords
- droplet actuator
- bead manipulation
- bead
- manipulation
- droplet
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/52—Containers specially adapted for storing or dispensing a reagent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
- B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/089—Virtual walls for guiding liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0424—Dielectrophoretic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0427—Electrowetting
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95771707P | 2007-08-24 | 2007-08-24 | |
| US98076707P | 2007-10-17 | 2007-10-17 | |
| PCT/US2008/074151 WO2009029561A2 (en) | 2007-08-24 | 2008-08-25 | Bead manipulations on a droplet actuator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0815698A2 true BRPI0815698A2 (pt) | 2017-06-13 |
Family
ID=40388098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0815698A BRPI0815698A2 (pt) | 2007-08-24 | 2008-08-25 | manipulação de contas em um atuador de gotículas. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8591830B2 (pt) |
| EP (1) | EP2188059B1 (pt) |
| JP (2) | JP5302966B2 (pt) |
| KR (1) | KR101451955B1 (pt) |
| CN (1) | CN101808751B (pt) |
| AU (1) | AU2008293652B2 (pt) |
| BR (1) | BRPI0815698A2 (pt) |
| CA (1) | CA2696604A1 (pt) |
| MX (1) | MX2010002079A (pt) |
| WO (1) | WO2009029561A2 (pt) |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1859330B1 (en) | 2005-01-28 | 2012-07-04 | Duke University | Apparatuses and methods for manipulating droplets on a printed circuit board |
| US20140193807A1 (en) | 2006-04-18 | 2014-07-10 | Advanced Liquid Logic, Inc. | Bead manipulation techniques |
| US8716015B2 (en) | 2006-04-18 | 2014-05-06 | Advanced Liquid Logic, Inc. | Manipulation of cells on a droplet actuator |
| US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
| US8637324B2 (en) | 2006-04-18 | 2014-01-28 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
| US8809068B2 (en) | 2006-04-18 | 2014-08-19 | Advanced Liquid Logic, Inc. | Manipulation of beads in droplets and methods for manipulating droplets |
| WO2009140671A2 (en) | 2008-05-16 | 2009-11-19 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods for manipulating beads |
| US10078078B2 (en) | 2006-04-18 | 2018-09-18 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
| US8658111B2 (en) | 2006-04-18 | 2014-02-25 | Advanced Liquid Logic, Inc. | Droplet actuators, modified fluids and methods |
| US9675972B2 (en) | 2006-05-09 | 2017-06-13 | Advanced Liquid Logic, Inc. | Method of concentrating beads in a droplet |
| US8685344B2 (en) | 2007-01-22 | 2014-04-01 | Advanced Liquid Logic, Inc. | Surface assisted fluid loading and droplet dispensing |
| EP2573562A3 (en) | 2007-02-09 | 2013-10-30 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods employing magnetic beads |
| EP2109774B1 (en) | 2007-02-15 | 2018-07-04 | Advanced Liquid Logic, Inc. | Capacitance detection in a droplet actuator |
| WO2009032863A2 (en) | 2007-09-04 | 2009-03-12 | Advanced Liquid Logic, Inc. | Droplet actuator with improved top substrate |
| US9631244B2 (en) | 2007-10-17 | 2017-04-25 | Advanced Liquid Logic, Inc. | Reagent storage on a droplet actuator |
| CA2709928A1 (en) | 2007-12-23 | 2009-07-09 | Advanced Liquid Logic, Inc. | Droplet actuator configurations and methods of conducting droplet operations |
| US8852952B2 (en) | 2008-05-03 | 2014-10-07 | Advanced Liquid Logic, Inc. | Method of loading a droplet actuator |
| US8877512B2 (en) * | 2009-01-23 | 2014-11-04 | Advanced Liquid Logic, Inc. | Bubble formation techniques using physical or chemical features to retain a gas bubble within a droplet actuator |
| GB0913258D0 (en) | 2009-07-29 | 2009-09-02 | Dynex Technologies Inc | Reagent dispenser |
| US9523701B2 (en) | 2009-07-29 | 2016-12-20 | Dynex Technologies, Inc. | Sample plate systems and methods |
| US8926065B2 (en) | 2009-08-14 | 2015-01-06 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods |
| WO2011057197A2 (en) | 2009-11-06 | 2011-05-12 | Advanced Liquid Logic, Inc. | Integrated droplet actuator for gel electrophoresis and molecular analysis |
| EP2516669B1 (en) | 2009-12-21 | 2016-10-12 | Advanced Liquid Logic, Inc. | Enzyme assays on a droplet actuator |
| EP2553473A4 (en) | 2010-03-30 | 2016-08-10 | Advanced Liquid Logic Inc | DROPLET OPERATION PLATFORM |
| US10232374B2 (en) | 2010-05-05 | 2019-03-19 | Miroculus Inc. | Method of processing dried samples using digital microfluidic device |
| EP2588322B1 (en) | 2010-06-30 | 2015-06-17 | Advanced Liquid Logic, Inc. | Droplet actuator assemblies and methods of making same |
| WO2012154745A2 (en) | 2011-05-09 | 2012-11-15 | Advanced Liquid Logic, Inc. | Microfluidic feedback using impedance detection |
| US9140635B2 (en) | 2011-05-10 | 2015-09-22 | Advanced Liquid Logic, Inc. | Assay for measuring enzymatic modification of a substrate by a glycoprotein having enzymatic activity |
| US8901043B2 (en) | 2011-07-06 | 2014-12-02 | Advanced Liquid Logic, Inc. | Systems for and methods of hybrid pyrosequencing |
| WO2013009927A2 (en) | 2011-07-11 | 2013-01-17 | Advanced Liquid Logic, Inc. | Droplet actuators and techniques for droplet-based assays |
| KR20130009504A (ko) | 2011-07-15 | 2013-01-23 | 삼성전자주식회사 | 개구 조절 방법 및 개구 조절 소자 |
| WO2013016413A2 (en) | 2011-07-25 | 2013-01-31 | Advanced Liquid Logic Inc | Droplet actuator apparatus and system |
| WO2013070627A2 (en) | 2011-11-07 | 2013-05-16 | Illumina, Inc. | Integrated sequencing apparatuses and methods of use |
| WO2013078216A1 (en) | 2011-11-21 | 2013-05-30 | Advanced Liquid Logic Inc | Glucose-6-phosphate dehydrogenase assays |
| DE102012002272A1 (de) | 2012-02-04 | 2013-08-08 | Clariant International Ltd. | Pestizid-Zusammensetzungen |
| ES2599504T3 (es) | 2012-05-30 | 2017-02-02 | Clariant International Ltd | Utilización de N-metil-N-acil-glucaminas como agentes solubilizantes |
| IN2014DN09937A (pt) | 2012-05-30 | 2015-08-14 | Clariant Int Ltd | |
| US9223317B2 (en) | 2012-06-14 | 2015-12-29 | Advanced Liquid Logic, Inc. | Droplet actuators that include molecular barrier coatings |
| EP2867645B1 (en) | 2012-06-27 | 2019-06-05 | Advanced Liquid Logic, Inc. | Techniques and droplet actuator designs for reducing bubble formation |
| US10316872B2 (en) | 2012-08-27 | 2019-06-11 | The Board Of Trustees Of The Leland Stanford Junior University | Two-dimensional magnetic trap arrays for droplet control |
| US9863913B2 (en) | 2012-10-15 | 2018-01-09 | Advanced Liquid Logic, Inc. | Digital microfluidics cartridge and system for operating a flow cell |
| US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
| JP1628115S (pt) | 2012-10-24 | 2019-04-01 | ||
| WO2014078100A1 (en) * | 2012-11-02 | 2014-05-22 | Advanced Liquid Logic, Inc. | Mechanisms for and methods of loading a droplet actuator with filler fluid |
| DE102012021647A1 (de) | 2012-11-03 | 2014-05-08 | Clariant International Ltd. | Wässrige Adjuvant-Zusammensetzungen |
| US9366647B2 (en) * | 2013-03-14 | 2016-06-14 | Taiwan Semiconductor Manufacturing Company, Ltd. | Optical detection for bio-entities |
| US11029310B2 (en) | 2013-03-14 | 2021-06-08 | Wisconsin Alumni Research Foundation | Device and method for extracting a targeted fraction from a sample |
| CN107866286A (zh) | 2013-03-15 | 2018-04-03 | 金马克诊断股份有限公司 | 用于操纵可变形流体容器的系统、方法和设备 |
| KR101997258B1 (ko) * | 2013-06-28 | 2019-10-01 | 엘지이노텍 주식회사 | 발광 소자 패키지 |
| US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
| USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
| KR101480651B1 (ko) * | 2013-12-09 | 2015-01-09 | 현대자동차주식회사 | 오브젝트 처리 방법 및 이를 지원하는 차량 |
| DE202014008415U1 (de) | 2014-02-19 | 2014-11-25 | Clariant International Ltd. | Wässrige Adjuvant-Zusammensetzung zur Wirkungssteigerung von Elektrolyt-Wirkstoffen |
| DE102014005771A1 (de) | 2014-04-23 | 2015-10-29 | Clariant International Ltd. | Verwendung von wässrigen driftreduzierenden Zusammensetzungen |
| US20150306598A1 (en) * | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus |
| CA2945177C (en) * | 2014-04-25 | 2021-12-21 | Berkeley Lights, Inc. | Providing dep manipulation devices and controllable electrowetting devices in the same microfluidic apparatus |
| US11192107B2 (en) * | 2014-04-25 | 2021-12-07 | Berkeley Lights, Inc. | DEP force control and electrowetting control in different sections of the same microfluidic apparatus |
| US20150306599A1 (en) | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus |
| DE102014012022A1 (de) | 2014-08-13 | 2016-02-18 | Clariant International Ltd. | Organische Ammoniumsalze von anionischen Pestiziden |
| EP3218108B1 (en) | 2014-11-11 | 2020-09-02 | Genmark Diagnostics Inc. | Fluid sample processing cartridge and use thereof |
| US9598722B2 (en) | 2014-11-11 | 2017-03-21 | Genmark Diagnostics, Inc. | Cartridge for performing assays in a closed sample preparation and reaction system |
| US10005080B2 (en) | 2014-11-11 | 2018-06-26 | Genmark Diagnostics, Inc. | Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation |
| DE102014018274A1 (de) | 2014-12-12 | 2015-07-30 | Clariant International Ltd. | Zuckertenside und deren Verwendung in agrochemischen Zusammensetzungen |
| ES2890657T3 (es) | 2014-12-19 | 2022-01-21 | Clariant Int Ltd | Composiciones adyuvantes acuosas que contienen electrolitos, composiciones que contienen principios activos y su uso |
| JP6622811B2 (ja) | 2014-12-31 | 2019-12-18 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | デジタルマイクロ流体希釈装置、システムおよび関連方法 |
| US10723988B2 (en) | 2015-04-22 | 2020-07-28 | Berkeley Lights, Inc. | Microfluidic cell culture |
| CN108026494A (zh) | 2015-06-05 | 2018-05-11 | 米罗库鲁斯公司 | 限制蒸发和表面结垢的空气基质数字微流控装置和方法 |
| US10695762B2 (en) | 2015-06-05 | 2020-06-30 | Miroculus Inc. | Evaporation management in digital microfluidic devices |
| NL2015287B1 (en) * | 2015-08-10 | 2017-02-28 | Micronit Microfluidics Bv | Channel for trapping particles to be fed to said channel with a fluid. |
| DE102015219608B4 (de) | 2015-10-09 | 2018-05-03 | Clariant International Ltd | Universelle Pigmentdispersionen auf Basis von N-Alkylglukaminen |
| DE102015219651A1 (de) | 2015-10-09 | 2017-04-13 | Clariant International Ltd. | Zusammensetzungen enthaltend Zuckeramin und Fettsäure |
| US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| DE102016207877A1 (de) | 2016-05-09 | 2017-11-09 | Clariant International Ltd | Stabilisatoren für Silikatfarben |
| IL263274B2 (en) | 2016-05-26 | 2023-10-01 | Berkeley Lights Inc | Covalently adapted surfaces, kits and methods for their production and uses |
| DE102016210164A1 (de) | 2016-06-08 | 2017-12-14 | Clariant International Ltd | Verwendung von N-substituierten Pyrrolidonen zur Förderung der Penetration von agrochemischen Wirkstoffen |
| CN109715781A (zh) | 2016-08-22 | 2019-05-03 | 米罗库鲁斯公司 | 用于数字微流控设备中的并行液滴控制的反馈系统 |
| EP3516401B1 (en) | 2016-09-19 | 2025-07-30 | Roche Diagnostics GmbH | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
| CN110383061A (zh) | 2016-12-28 | 2019-10-25 | 米罗库鲁斯公司 | 数字微流控设备和方法 |
| US11623219B2 (en) | 2017-04-04 | 2023-04-11 | Miroculus Inc. | Digital microfluidics apparatuses and methods for manipulating and processing encapsulated droplets |
| US10544413B2 (en) | 2017-05-18 | 2020-01-28 | 10X Genomics, Inc. | Methods and systems for sorting droplets and beads |
| CN110945139B (zh) | 2017-05-18 | 2023-09-05 | 10X基因组学有限公司 | 用于分选液滴和珠的方法和系统 |
| US10730048B2 (en) * | 2017-06-21 | 2020-08-04 | Sharp Life Science (Eu) Limited | EWOD device with holdback feature for fluid loading |
| EP3658908B1 (en) | 2017-07-24 | 2025-11-12 | Integra Biosciences AG | Digital microfluidics systems and methods with integrated plasma collection device |
| US20190064173A1 (en) | 2017-08-22 | 2019-02-28 | 10X Genomics, Inc. | Methods of producing droplets including a particle and an analyte |
| CA3073058A1 (en) | 2017-09-01 | 2019-03-07 | Miroculus Inc. | Digital microfluidics devices and methods of using them |
| US20190110472A1 (en) | 2017-10-12 | 2019-04-18 | Clariant International, Ltd. | Active ingredient compositions comprising n-alkenoyl-n-alkylglucamides and the use thereof |
| WO2019083852A1 (en) | 2017-10-26 | 2019-05-02 | 10X Genomics, Inc. | MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING |
| WO2019226919A1 (en) | 2018-05-23 | 2019-11-28 | Miroculus Inc. | Control of evaporation in digital microfluidics |
| CA3215214A1 (en) * | 2018-09-06 | 2020-03-06 | Nicoya Lifesciences Inc. | Plasmon resonance (pr) system and instrument, digital microfluidic (dmf) cartridge, and methods of using localized surface plasmon resonance (lspr) for analysis of analytes |
| GB2577607B (en) * | 2018-09-28 | 2023-05-17 | Guangdong Acxel Micro & Nano Tech Co Ltd | Droplet actuation |
| US10913067B2 (en) * | 2018-10-01 | 2021-02-09 | Sharp Life Science (Eu) Limited | Barrier droplet configurations against migration between droplets on AM-EWOD devices |
| EP3917670A4 (en) | 2019-01-31 | 2022-11-02 | Miroculus Inc. | ANTIFOULING COMPOSITIONS AND METHODS FOR HANDLING AND TREATING ENCAPSULATED DROPLET |
| WO2020176882A1 (en) | 2019-02-28 | 2020-09-03 | 10X Genomics, Inc. | Devices, systems, and methods for increasing droplet formation efficiency |
| US12582991B2 (en) | 2019-02-28 | 2026-03-24 | Integra Biosciences Ag | Digital microfluidics devices and methods of using them |
| CN109999929B (zh) * | 2019-03-28 | 2021-04-30 | 上海天马微电子有限公司 | 微流控装置及其驱动方法 |
| CN114206499B (zh) | 2019-04-08 | 2024-10-08 | 米罗库鲁斯公司 | 多盒式数字微流控装置和使用方法 |
| US12186751B2 (en) | 2019-06-28 | 2025-01-07 | 10X Genomics, Inc. | Devices and systems incorporating acoustic ordering and methods of use thereof |
| US11524298B2 (en) | 2019-07-25 | 2022-12-13 | Miroculus Inc. | Digital microfluidics devices and methods of use thereof |
| US12059679B2 (en) | 2019-11-19 | 2024-08-13 | 10X Genomics, Inc. | Methods and devices for sorting droplets and particles |
| WO2021252923A1 (en) | 2020-06-12 | 2021-12-16 | Genmark Diagnostics, Inc. | Systems and methods for assessing bays on diagnostic devices |
| US11772093B2 (en) | 2022-01-12 | 2023-10-03 | Miroculus Inc. | Methods of mechanical microfluidic manipulation |
| CN118201982A (zh) | 2022-08-18 | 2024-06-14 | 10X基因组学有限公司 | 具有含氟二醇添加剂的液滴形成装置和方法 |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4849340A (en) * | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
| JP3791999B2 (ja) * | 1997-03-24 | 2006-06-28 | 株式会社アドバンス | 液体微粒子ハンドリング装置 |
| US6565727B1 (en) * | 1999-01-25 | 2003-05-20 | Nanolytics, Inc. | Actuators for microfluidics without moving parts |
| US6294063B1 (en) * | 1999-02-12 | 2001-09-25 | Board Of Regents, The University Of Texas System | Method and apparatus for programmable fluidic processing |
| US6485690B1 (en) * | 1999-05-27 | 2002-11-26 | Orchid Biosciences, Inc. | Multiple fluid sample processor and system |
| EP1094318B1 (en) * | 1999-10-22 | 2007-03-28 | Ngk Insulators, Ltd. | DNA chip and method for producing the same |
| CN1204267C (zh) * | 2000-05-05 | 2005-06-01 | 朱学军 | 一种检测细胞内核酸的方法和装置 |
| US6773566B2 (en) * | 2000-08-31 | 2004-08-10 | Nanolytics, Inc. | Electrostatic actuators for microfluidics and methods for using same |
| CN1325909C (zh) * | 2000-09-27 | 2007-07-11 | 清华大学 | 用于微粒操纵与微粒导向的装置及其使用方法 |
| FR2817343B1 (fr) * | 2000-11-29 | 2003-05-09 | Commissariat Energie Atomique | Procede et dispositifs de transport et de concentration d'un analyte present dans un echantillon |
| JP3778041B2 (ja) * | 2000-12-08 | 2006-05-24 | コニカミノルタホールディングス株式会社 | 粒子分離機構及び粒子分離装置 |
| JP3805746B2 (ja) * | 2001-02-23 | 2006-08-09 | 独立行政法人科学技術振興機構 | 液体微粒子のハンドリング方法およびその装置 |
| JP3673854B2 (ja) * | 2001-05-11 | 2005-07-20 | 独立行政法人産業技術総合研究所 | 口径可変式吸引ノズルを備えたダスト試料採取装置 |
| US20020168297A1 (en) * | 2001-05-11 | 2002-11-14 | Igor Shvets | Method and device for dispensing of droplets |
| WO2002093245A1 (en) * | 2001-05-15 | 2002-11-21 | E Ink Corporation | Electrophoretic displays containing magnetic particles |
| JP2003084123A (ja) * | 2001-06-29 | 2003-03-19 | Seiko Epson Corp | カラーフィルタ基板、カラーフィルタ基板の製造方法、液晶表示装置、電気光学装置、電気光学装置の製造方法及び電子機器 |
| US6705716B2 (en) * | 2001-10-11 | 2004-03-16 | Hewlett-Packard Development Company, L.P. | Thermal ink jet printer for printing an image on a receiver and method of assembling the printer |
| AU2002359508A1 (en) * | 2001-11-26 | 2003-06-10 | Keck Graduate Institute | Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like |
| FR2841063B1 (fr) * | 2002-06-18 | 2004-09-17 | Commissariat Energie Atomique | Dispositif de deplacement de petits volumes de liquide le long d'un micro-catenaire par des forces electrostatiques |
| JP4031322B2 (ja) * | 2002-08-26 | 2008-01-09 | 独立行政法人科学技術振興機構 | 液滴操作装置 |
| WO2004027379A2 (en) * | 2002-09-20 | 2004-04-01 | Novus Molecular, Inc. | Methods and devices for active bioassay |
| US6911132B2 (en) * | 2002-09-24 | 2005-06-28 | Duke University | Apparatus for manipulating droplets by electrowetting-based techniques |
| US7547380B2 (en) * | 2003-01-13 | 2009-06-16 | North Carolina State University | Droplet transportation devices and methods having a fluid surface |
| DE10311622B4 (de) * | 2003-03-17 | 2005-06-09 | Disetronic Licensing Ag | Sensorisches Membran-Osmometer und osmotisches Messverfahren zur quantitativen Bestimmung niedermolekularer Affinitätsliganden |
| EP2305173B1 (en) * | 2003-03-28 | 2016-05-11 | Inguran, LLC | Apparatus and methods for providing sorted particles |
| TWI230760B (en) * | 2003-07-29 | 2005-04-11 | Univ Tsinghua | Electrowetting electrode design with electromagnetic field for actuation of the magnetic-beads biochemical detection system |
| CA2479452C (en) * | 2003-08-30 | 2008-11-04 | F.Hoffmann-La Roche Ag | Method and device for determining analytes in a liquid |
| US7470397B2 (en) * | 2003-10-24 | 2008-12-30 | Adhesives Research, Inc. | Disintegratable films for diagnostic devices |
| DE10352535A1 (de) | 2003-11-07 | 2005-06-16 | Steag Microparts Gmbh | Mikrostrukturierte Trennvorrichtung und Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Partikel enthaltenden Flüssigkeit |
| CN100478075C (zh) * | 2003-11-17 | 2009-04-15 | 皇家飞利浦电子股份有限公司 | 用于操纵流体实体的系统 |
| CA2553025A1 (en) * | 2004-01-14 | 2005-07-28 | Luminex Corporation | Methods and systems for dynamic range expansion |
| US20080226500A1 (en) * | 2004-01-15 | 2008-09-18 | Mitsuhiro Shikida | Chemical Analytic Apparatus and Chemical Analytic Method |
| JP4068581B2 (ja) * | 2004-03-08 | 2008-03-26 | 独立行政法人科学技術振興機構 | ナノ空隙制御による微粒子のサイズ分離分析法およびその装置 |
| JP4486383B2 (ja) * | 2004-03-08 | 2010-06-23 | 株式会社アドバンテスト | パターン発生器、及び試験装置 |
| FR2872715B1 (fr) * | 2004-07-08 | 2006-11-17 | Commissariat Energie Atomique | Microreacteur goutte |
| FR2872809B1 (fr) * | 2004-07-09 | 2006-09-15 | Commissariat Energie Atomique | Methode d'adressage d'electrodes |
| CN2735342Y (zh) * | 2004-10-20 | 2005-10-19 | 清华大学 | 一种介质层上的电润湿微液滴驱动器 |
| DE102004059280B4 (de) * | 2004-12-09 | 2007-08-16 | Dräger Safety AG & Co. KGaA | Elektrochemischer Gassensor |
| US7458661B2 (en) * | 2005-01-25 | 2008-12-02 | The Regents Of The University Of California | Method and apparatus for promoting the complete transfer of liquid drops from a nozzle |
| EP1859330B1 (en) * | 2005-01-28 | 2012-07-04 | Duke University | Apparatuses and methods for manipulating droplets on a printed circuit board |
| FR2884437B1 (fr) * | 2005-04-19 | 2007-07-20 | Commissariat Energie Atomique | Dispositif et procede microfluidique de transfert de matiere entre deux phases immiscibles. |
| CA2606750C (en) | 2005-05-11 | 2015-11-24 | Nanolytics, Inc. | Method and device for conducting biochemical or chemical reactions at multiple temperatures |
| JP2006329904A (ja) * | 2005-05-30 | 2006-12-07 | Hitachi High-Technologies Corp | 液体搬送デバイス及び分析システム |
| JP4500733B2 (ja) * | 2005-05-30 | 2010-07-14 | 株式会社日立ハイテクノロジーズ | 化学分析装置 |
| US20070023292A1 (en) * | 2005-07-26 | 2007-02-01 | The Regents Of The University Of California | Small object moving on printed circuit board |
| CN102622746B (zh) * | 2005-09-21 | 2016-05-25 | 卢米尼克斯股份有限公司 | 图像数据处理的方法和系统 |
| KR100781739B1 (ko) | 2005-09-28 | 2007-12-03 | 삼성전자주식회사 | 전기습윤에서 액적의 접촉각 변위 및 변화속도 증가방법 및상기 방법에 의해 형성된 액적을 적용한 액적제어장치 |
| US7344679B2 (en) * | 2005-10-14 | 2008-03-18 | International Business Machines Corporation | Method and apparatus for point of care osmolarity testing |
| CN101351270A (zh) * | 2005-10-22 | 2009-01-21 | 精华微技有限公司 | 从用于芯片微流控的液柱中抽取液滴 |
| US7365022B2 (en) * | 2006-01-20 | 2008-04-29 | Palo Alto Research Center Incorporated | Additive printed mask process and structures produced thereby |
| US20070207513A1 (en) * | 2006-03-03 | 2007-09-06 | Luminex Corporation | Methods, Products, and Kits for Identifying an Analyte in a Sample |
| US7439014B2 (en) * | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
| US7815871B2 (en) | 2006-04-18 | 2010-10-19 | Advanced Liquid Logic, Inc. | Droplet microactuator system |
| WO2010027894A2 (en) | 2008-08-27 | 2010-03-11 | Advanced Liquid Logic, Inc. | Droplet actuators, modified fluids and methods |
| US7901947B2 (en) * | 2006-04-18 | 2011-03-08 | Advanced Liquid Logic, Inc. | Droplet-based particle sorting |
| EP2016189B1 (en) | 2006-04-18 | 2012-01-25 | Advanced Liquid Logic, Inc. | Droplet-based pyrosequencing |
| CN101490562B (zh) * | 2006-07-10 | 2012-12-19 | 株式会社日立高新技术 | 液体输送设备 |
| US9266076B2 (en) * | 2006-11-02 | 2016-02-23 | The Regents Of The University Of California | Method and apparatus for real-time feedback control of electrical manipulation of droplets on chip |
| US8202491B2 (en) * | 2006-11-21 | 2012-06-19 | Bioscale, Inc. | Apparatus for analyte processing |
| EP2857526B1 (en) * | 2006-12-13 | 2016-08-17 | Luminex Corporation | Systems and methods for multiplex analysis of PCR in real time |
| EP2573562A3 (en) | 2007-02-09 | 2013-10-30 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods employing magnetic beads |
| EP2109774B1 (en) | 2007-02-15 | 2018-07-04 | Advanced Liquid Logic, Inc. | Capacitance detection in a droplet actuator |
| US8093062B2 (en) * | 2007-03-22 | 2012-01-10 | Theodore Winger | Enzymatic assays using umbelliferone substrates with cyclodextrins in droplets in oil |
| JP2010524002A (ja) * | 2007-04-10 | 2010-07-15 | アドヴァンスト リキッド ロジック インコーポレイテッド | 液滴分配装置および方法 |
| WO2008134153A1 (en) | 2007-04-23 | 2008-11-06 | Advanced Liquid Logic, Inc. | Bead-based multiplexed analytical methods and instrumentation |
| US20080283414A1 (en) * | 2007-05-17 | 2008-11-20 | Monroe Charles W | Electrowetting devices |
| WO2009003184A1 (en) | 2007-06-27 | 2008-12-31 | Digital Biosystems | Digital microfluidics based apparatus for heat-exchanging chemical processes |
| WO2009021173A1 (en) | 2007-08-08 | 2009-02-12 | Advanced Liquid Logic, Inc. | Use of additives for enhancing droplet operations |
| ES2438989T3 (es) * | 2008-05-13 | 2014-01-21 | Advanced Liquid Logic, Inc. | Dispositivos, sistemas y métodos accionadores de gotitas |
| US8093064B2 (en) * | 2008-05-15 | 2012-01-10 | The Regents Of The University Of California | Method for using magnetic particles in droplet microfluidics |
-
2008
- 2008-08-25 BR BRPI0815698A patent/BRPI0815698A2/pt not_active IP Right Cessation
- 2008-08-25 WO PCT/US2008/074151 patent/WO2009029561A2/en not_active Ceased
- 2008-08-25 AU AU2008293652A patent/AU2008293652B2/en not_active Ceased
- 2008-08-25 US US12/673,893 patent/US8591830B2/en not_active Expired - Fee Related
- 2008-08-25 KR KR1020107005688A patent/KR101451955B1/ko not_active Expired - Fee Related
- 2008-08-25 CN CN200880104134.0A patent/CN101808751B/zh not_active Expired - Fee Related
- 2008-08-25 JP JP2010522099A patent/JP5302966B2/ja not_active Expired - Fee Related
- 2008-08-25 CA CA2696604A patent/CA2696604A1/en not_active Abandoned
- 2008-08-25 EP EP08828680.2A patent/EP2188059B1/en active Active
- 2008-08-25 MX MX2010002079A patent/MX2010002079A/es active IP Right Grant
-
2013
- 2013-06-21 JP JP2013130180A patent/JP2013242321A/ja active Pending
- 2013-11-25 US US14/089,298 patent/US20140174933A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101808751B (zh) | 2014-01-29 |
| JP2010537203A (ja) | 2010-12-02 |
| CA2696604A1 (en) | 2009-03-05 |
| EP2188059A4 (en) | 2015-05-20 |
| AU2008293652A1 (en) | 2009-03-05 |
| US20110086377A1 (en) | 2011-04-14 |
| CN101808751A (zh) | 2010-08-18 |
| AU2008293652B2 (en) | 2013-02-21 |
| KR20100133943A (ko) | 2010-12-22 |
| WO2009029561A3 (en) | 2009-05-22 |
| US8591830B2 (en) | 2013-11-26 |
| JP5302966B2 (ja) | 2013-10-02 |
| WO2009029561A2 (en) | 2009-03-05 |
| JP2013242321A (ja) | 2013-12-05 |
| US20140174933A1 (en) | 2014-06-26 |
| EP2188059A2 (en) | 2010-05-26 |
| MX2010002079A (es) | 2010-08-09 |
| EP2188059B1 (en) | 2016-05-04 |
| KR101451955B1 (ko) | 2014-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0815698A2 (pt) | manipulação de contas em um atuador de gotículas. | |
| EP2121329A4 (en) | DROP EJECTOR STRUCTURES | |
| DE502007003917D1 (de) | Querträger, insbesondere ein Cockpitquerträger | |
| BRPI0914528A2 (pt) | acionador de válvula. | |
| BRPI0809508A2 (pt) | Unidade de válvula operada por solenóide. | |
| DE602007011617D1 (de) | Klappenstellmotor | |
| EP2180217A4 (en) | Control valve | |
| DE502007005527D1 (de) | Dreh-/drücksteller | |
| BRPI0813806A2 (pt) | Dispositivo operado por pedal. | |
| DE602008006287D1 (de) | Fahrradbetätigungsvorrichtung | |
| CL2008000325S1 (es) | Automovil. | |
| BRPI0920992A2 (pt) | atuador de movimento acionado. | |
| CL2008000782S1 (es) | Automovil. | |
| IT1391475B1 (it) | Dispositivo di controllo di posizione. | |
| BRPI0819600A2 (pt) | Servoválvula. | |
| CL2008000916S1 (es) | Automovil. | |
| DE602008002004D1 (de) | Aktuatoranordnung | |
| FR2919972B1 (fr) | Actionneur piezoelectrique. | |
| BRPI0818283A2 (pt) | Veículo. | |
| FR2903752B1 (fr) | Valve de pneumatique. | |
| FR2909834B1 (fr) | Andaineuse transversale. | |
| FI7785U1 (fi) | Toimilaite | |
| FR2910380B1 (fr) | Pneumatique a sommet rigide. | |
| FR2898022B1 (fr) | Parapluie a egouttoir. | |
| ES1061965Y (es) | Tractocamion polivalente. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2529 DE 25-06-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |