BRPI0815713A2 - Formulações lipossômicas de compostos de ácido borônico. - Google Patents

Formulações lipossômicas de compostos de ácido borônico.

Info

Publication number
BRPI0815713A2
BRPI0815713A2 BRPI0815713-8A2A BRPI0815713A BRPI0815713A2 BR PI0815713 A2 BRPI0815713 A2 BR PI0815713A2 BR PI0815713 A BRPI0815713 A BR PI0815713A BR PI0815713 A2 BRPI0815713 A2 BR PI0815713A2
Authority
BR
Brazil
Prior art keywords
boronic acid
acid compounds
liposomic
formulations
liposomic formulations
Prior art date
Application number
BRPI0815713-8A2A
Other languages
English (en)
Inventor
Yuanpeng Zhang
Anthony Huang
Bing Luo
Jinkang Wang
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0815713A2 publication Critical patent/BRPI0815713A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0815713-8A2A 2007-08-21 2008-08-21 Formulações lipossômicas de compostos de ácido borônico. BRPI0815713A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95704907P 2007-08-21 2007-08-21
PCT/US2008/073844 WO2009026430A2 (en) 2007-08-21 2008-08-21 Liposome formulations of boronic acid compounds

Publications (1)

Publication Number Publication Date
BRPI0815713A2 true BRPI0815713A2 (pt) 2015-02-10

Family

ID=39772869

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815713-8A2A BRPI0815713A2 (pt) 2007-08-21 2008-08-21 Formulações lipossômicas de compostos de ácido borônico.

Country Status (16)

Country Link
US (1) US20090092662A1 (pt)
EP (1) EP2190412A2 (pt)
JP (1) JP2010536875A (pt)
KR (1) KR20100066515A (pt)
CN (1) CN101795672A (pt)
AU (1) AU2008288920A1 (pt)
BR (1) BRPI0815713A2 (pt)
CA (1) CA2697044A1 (pt)
CO (1) CO6260057A2 (pt)
EA (1) EA201070297A1 (pt)
EC (1) ECSP109983A (pt)
MX (1) MX2010002101A (pt)
NI (1) NI201000030A (pt)
SV (1) SV2010003487A (pt)
WO (1) WO2009026430A2 (pt)
ZA (1) ZA201002011B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10125388B2 (en) * 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
WO2009155135A1 (en) * 2008-06-18 2009-12-23 Alza Corporation Composition comprising liposome-entrapped doxorubicin and methods of admnistration for treatment of multiple myeloma
US9034829B1 (en) * 2011-10-27 2015-05-19 Northwestern University pH-sensitive polymer-drug conjugates for targeted delivery of therapeutics
CN111116622A (zh) 2014-02-03 2020-05-08 俄亥俄州创新基金会 硼酸酯和其药物制剂
AU2016256979B2 (en) * 2015-05-04 2021-01-28 Genfit Method for preparing transmembrane pH-gradient vesicles
CN109045272A (zh) * 2018-08-01 2018-12-21 厦门市壳聚糖生物科技有限公司 一种硼替佐米磷脂复合物及其制备方法与应用
US20220387460A1 (en) * 2019-11-11 2022-12-08 Washington University Liposome compositions and methods of treatment targeted to tumor endothelium
JP2025526608A (ja) * 2022-08-12 2025-08-15 アヴィコ レディオファーマシューティカルズ エルエルシー ホウ素中性子捕捉療法のための小分子
AR130533A1 (es) * 2022-09-21 2024-12-18 Aviko Radiopharmaceuticals Llc Moléculas pequeñas para terapias de captura de neutrones en boro

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0314450A (pt) * 2002-09-09 2005-07-26 Trigen Ltd Sais de ácido borÈnico com adição de uma base farmaceuticamente aceitável, formulação farmacêutica, e uso dos referidos sais para preparar uma formulação farmacêutica
EP1802278A4 (en) * 2004-10-22 2012-08-01 Dynamis Therapeutics Inc DERIVATIVE ADMINISTRATION OF N-METHYL-GLUCAMINE AND N-METHYL-GLUCAMINE COMPOUNDS
TW200618820A (en) * 2004-11-05 2006-06-16 Alza Corp Liposome formulations of boronic acid compounds

Also Published As

Publication number Publication date
ZA201002011B (en) 2011-05-25
NI201000030A (es) 2010-07-29
EP2190412A2 (en) 2010-06-02
JP2010536875A (ja) 2010-12-02
WO2009026430A2 (en) 2009-02-26
MX2010002101A (es) 2010-03-26
AU2008288920A1 (en) 2009-02-26
CO6260057A2 (es) 2011-03-22
WO2009026430A3 (en) 2009-11-26
SV2010003487A (es) 2010-08-10
ECSP109983A (es) 2010-04-30
EA201070297A1 (ru) 2010-08-30
KR20100066515A (ko) 2010-06-17
CN101795672A (zh) 2010-08-04
CA2697044A1 (en) 2009-02-26
US20090092662A1 (en) 2009-04-09

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/69 (2006.01), A61K 9/127 (2006.01), A61K 4