BRPI0818338A2 - Composto de pirimidil indolina - Google Patents

Composto de pirimidil indolina

Info

Publication number
BRPI0818338A2
BRPI0818338A2 BRPI0818338A BRPI0818338A2 BR PI0818338 A2 BRPI0818338 A2 BR PI0818338A2 BR PI0818338 A BRPI0818338 A BR PI0818338A BR PI0818338 A2 BRPI0818338 A2 BR PI0818338A2
Authority
BR
Brazil
Prior art keywords
pyrimidil
indoline
compound
pyrimidil compound
indoline pyrimidil
Prior art date
Application number
Other languages
English (en)
Inventor
Toshio Kaneko
Takeshi Shida
Koji Matsumoto
Kazumasa Aoki
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of BRPI0818338A2 publication Critical patent/BRPI0818338A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0818338 2007-10-16 2008-10-15 Composto de pirimidil indolina BRPI0818338A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007268937 2007-10-16
PCT/JP2008/068607 WO2009051119A1 (ja) 2007-10-16 2008-10-15 ピリミジルインドリン化合物

Publications (1)

Publication Number Publication Date
BRPI0818338A2 true BRPI0818338A2 (pt) 2015-04-22

Family

ID=40567381

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818338 BRPI0818338A2 (pt) 2007-10-16 2008-10-15 Composto de pirimidil indolina

Country Status (16)

Country Link
US (1) US8232287B2 (pt)
EP (1) EP2210886B1 (pt)
JP (1) JP5317354B2 (pt)
KR (1) KR101536021B1 (pt)
CN (1) CN101896481B (pt)
AU (1) AU2008312948C1 (pt)
BR (1) BRPI0818338A2 (pt)
CA (1) CA2710182C (pt)
IL (1) IL205057A0 (pt)
MX (1) MX2010004232A (pt)
MY (1) MY151295A (pt)
NZ (1) NZ585284A (pt)
RU (1) RU2464269C2 (pt)
TW (1) TWI421074B (pt)
WO (1) WO2009051119A1 (pt)
ZA (1) ZA201002552B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2399914A4 (en) * 2009-02-18 2012-08-29 Takeda Pharmaceutical FUSED HETEROCYCLIC CORE COMPOUND
JP2012526096A (ja) * 2009-05-08 2012-10-25 ファイザー・インク Ｇｐｒ１１９調節因子
JP2012526097A (ja) * 2009-05-08 2012-10-25 ファイザー・インク Ｇｐｒ１１９調節因子
JP2012530758A (ja) * 2009-06-24 2012-12-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物、医薬組成物及びそれに関する方法
NZ596445A (en) 2009-06-24 2013-04-26 Boehringer Ingelheim Int New compounds, pharmaceutical composition and methods relating thereto
WO2011017296A1 (en) * 2009-08-04 2011-02-10 Schering Corporation 4, 5, 6-trisubstituted pyrimidine derivatives as factor ixa inhibitors
EP2474540A4 (en) * 2009-08-31 2013-03-13 Nippon Chemiphar Co GPR119 AGONIST
EP2504342A1 (en) * 2009-11-23 2012-10-03 Pfizer Inc. Imidazo-pyrazoles as gpr119 inhibitors
FR2955580A1 (fr) * 2010-01-28 2011-07-29 Sanofi Aventis Derives de carbamate d'alkyl-heterocycles, leur preparation et leur application en therapeutique
EP2526100B1 (en) 2010-01-20 2013-12-04 Sanofi Alkyl-heterocycle carbamate derivatives, their preparation and their therapeutic application
TW201204733A (en) 2010-06-25 2012-02-01 Kowa Co Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same
WO2012025811A1 (en) * 2010-08-23 2012-03-01 Lupin Limited Indolylpyrimidines as modulators of gpr119
AU2011311183B2 (en) * 2010-10-08 2014-09-25 Cadila Healthcare Limited Novel GPR 119 agonists
EP2643311A1 (en) * 2010-11-26 2013-10-02 Lupin Limited Bicyclic gpr119 modulators
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
HK1200824A1 (en) 2012-01-18 2015-08-14 Daiichi Sankyo Company, Limited Substituted phenylazole derivative
WO2014156196A1 (ja) * 2013-03-29 2014-10-02 一般社団法人ファルマバレープロジェクト支援機構 ２型糖尿病治療剤
PH12021551324A1 (en) * 2019-01-08 2022-04-25 Kyorin Seiyaku Kk 15-pgdh inhibitor
US12304897B2 (en) 2019-01-31 2025-05-20 Kyorin Pharmaceutical Co., Ltd. 15-PGDH inhibitors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW406075B (en) * 1994-12-13 2000-09-21 Upjohn Co Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds
US7101869B2 (en) 1999-11-30 2006-09-05 Pfizer Inc. 2,4-diaminopyrimidine compounds useful as immunosuppressants
OA12097A (en) * 1999-11-30 2006-05-04 Pfizer Prod Inc 2,4-Diaminopyrimidine compounds useful as immunosuppressants.
ES2307102T3 (es) 2002-06-19 2008-11-16 Biovitrum Ab (Publ) Piperazinilpirazinas como moduladores del receptor de la serotonina 5-ht2c.
US7078419B2 (en) * 2003-03-10 2006-07-18 Boehringer Ingelheim Pharmaceuticals, Inc. Cytokine inhibitors
CN100509798C (zh) * 2003-07-11 2009-07-08 艾尼纳制药公司 作为新陈代谢调节剂的三取代芳基和杂芳基衍生物以及预防和治疗与其相关之病症
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
FR2866884B1 (fr) 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
HRP20090093T3 (en) 2004-06-04 2009-03-31 Arena Pharmaceuticals Inc. Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
NZ564759A (en) 2005-06-30 2011-08-26 Prosidion Ltd GPCR agonists
JP2009543805A (ja) * 2006-07-13 2009-12-10 スミスクライン ビーチャム コーポレーション インドリン誘導体及びｇｐｒ１１９作動物質

Also Published As

Publication number Publication date
AU2008312948A1 (en) 2009-04-23
CA2710182C (en) 2012-08-14
CN101896481A (zh) 2010-11-24
JPWO2009051119A1 (ja) 2011-03-03
IL205057A0 (en) 2010-11-30
AU2008312948C1 (en) 2012-08-09
CN101896481B (zh) 2014-04-30
RU2010119487A (ru) 2011-11-27
WO2009051119A1 (ja) 2009-04-23
EP2210886B1 (en) 2015-09-23
CA2710182A1 (en) 2009-04-23
EP2210886A4 (en) 2011-08-17
JP5317354B2 (ja) 2013-10-16
US20100292259A1 (en) 2010-11-18
US8232287B2 (en) 2012-07-31
TW200922588A (en) 2009-06-01
KR101536021B1 (ko) 2015-07-10
EP2210886A1 (en) 2010-07-28
RU2464269C2 (ru) 2012-10-20
AU2008312948B2 (en) 2012-03-01
KR20100071068A (ko) 2010-06-28
ZA201002552B (en) 2011-10-26
NZ585284A (en) 2011-03-31
MX2010004232A (es) 2010-09-30
MY151295A (en) 2014-04-30
TWI421074B (zh) 2014-01-01

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]