BRPI0811264A2 - Compostos - Google Patents

Compostos

Info

Publication number: BRPI0811264A2
Authority: BR; Brazil
Prior art keywords: compounds
Prior art date: 2007-05-24

Application number

BRPI0811264-9A2A

Other languages

English (en)

Inventor

John Matsoukas

Michael Maragoudakis

Dimitrios Vlaxakos

Original Assignee

Eldrug S A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-24

Filing date

2008-05-23

Publication date

2014-11-04

2007-05-24 Priority claimed from GR20070100312A external-priority patent/GR1005999B/el

2007-07-26 Priority claimed from GB0714603A external-priority patent/GB0714603D0/en

2008-05-23 Application filed by Eldrug S A filed Critical Eldrug S A

2014-11-04 Publication of BRPI0811264A2 publication Critical patent/BRPI0811264A2/pt

Links

150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)

BRPI0811264-9A2A 2007-05-24 2008-05-23 Compostos BRPI0811264A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GR20070100312A GR1005999B (el)	2007-05-24	2007-05-24	Ανταγωνιστες του υποδοχεα της αγγειοτενσινης με βαση 4(5) υποκατεστημενα ιμιδαζολια, συνθετικες μεθοδοι και διαδερμικη χορηγηση στην θεραπεια της υπερτασης και καρδειοαγγειακων ασθενειων
GB0714603A GB0714603D0 (en)	2007-07-26	2007-07-26	Compound
PCT/IB2008/002184 WO2008142576A2 (en)	2007-05-24	2008-05-23	1,(3,)5-substituted imidazoles, their use in the treatment of hypertension and methods for their preparation

Publications (1)

Publication Number	Publication Date
BRPI0811264A2 true BRPI0811264A2 (pt)	2014-11-04

Family

ID=40032238

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0811264-9A2A BRPI0811264A2 (pt)	2007-05-24	2008-05-23	Compostos

Country Status (12)

Country	Link
US (1)	US8563586B2 (pt)
EP (1)	EP2162441B1 (pt)
JP (1)	JP2010527987A (pt)
KR (1)	KR20100031113A (pt)
CN (1)	CN101765590B (pt)
AU (1)	AU2008252485A1 (pt)
BR (1)	BRPI0811264A2 (pt)
CA (1)	CA2687975A1 (pt)
IL (1)	IL202293A0 (pt)
MX (1)	MX2009012755A (pt)
RU (1)	RU2009148050A (pt)
WO (1)	WO2008142576A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200838501A (en)	2007-02-02	2008-10-01	Theravance Inc	Dual-acting antihypertensive agents
TWI448284B (zh)	2007-04-24	2014-08-11	Theravance Inc	雙效抗高血壓劑
TWI406850B (zh)	2007-06-05	2013-09-01	Theravance Inc	雙效苯并咪唑抗高血壓劑
US20100216854A1 (en) *	2007-08-01	2010-08-26	Eldrug S.A.	1,3 and 1,3,5 substituted imidazoles as antihypertensives
JP2010538071A (ja)	2007-09-07	2010-12-09	セラヴァンス，インコーポレーテッド	二重作用性降圧剤
EP2225210B1 (en)	2007-12-11	2012-04-25	Theravance, Inc.	Dual-acting benzoimidazole derivative and their use as antihypertensive agents
JP2011518884A (ja)	2008-04-29	2011-06-30	セラヴァンス，インコーポレーテッド	二重活性抗高血圧剤
US7863309B2 (en)	2008-07-24	2011-01-04	Theravance, Inc.	Dual-acting antihypertensive agents
US7956054B2 (en)	2009-07-07	2011-06-07	Theravance, Inc.	Dual-acting pyrazole antihypertensive agents
EP2456762B1 (en)	2009-07-22	2013-10-16	Theravance, Inc.	Dual-acting oxazole antihypertensive agents
HUP0900788A2 (en) *	2009-12-16	2011-11-28	Sanofi Aventis	Process for producing 4-bromomethyl-biphenyl derivatives
WO2011090929A1 (en)	2010-01-19	2011-07-28	Theravance, Inc.	Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents
WO2012048022A2 (en) *	2010-10-05	2012-04-12	Nova Southeastern University	Methods and compositions for therapeutic modulation of aldosterone levels in heart disease
IN2014DN00144A (pt) *	2011-07-22	2015-05-22	Cambrex Karlskoga Ab
US9505737B2 (en)	2013-01-11	2016-11-29	Corsair Pharma, Inc.	Treprostinil derivative compounds and methods of using same
JP6625541B2 (ja) *	2014-08-29	2019-12-25	東京応化工業株式会社	イミダゾール化合物、金属表面処理液、金属の表面処理方法、及び積層体の製造方法
CN104892535B (zh) *	2015-06-03	2017-03-22	启东东岳药业有限公司	5‑(4’‑甲基‑[1,1’‑联苯]‑2‑基)‑1氢‑四唑的合成方法
TWI776812B (zh)	2016-06-02	2022-09-11	荷蘭商菲林公司	血管收縮素-1-受體拮抗劑
JP6979844B2 (ja) *	2017-10-06	2021-12-15	株式会社シマノ	回転伝達機構、及びそれを備えた魚釣用スピニングリール
JP7138685B2 (ja) *	2020-10-26	2022-09-16	コルセアファーマインコーポレイテッド	トレプロスチニル誘導体化合物およびその使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5250554A (en) *	1989-10-24	1993-10-05	Takeda Chemical Industries, Ltd.	Benzimidazole derivatives useful as angiotensin II inhibitors
IL95975A (en) *	1989-10-24	1997-06-10	Takeda Chemical Industries Ltd	N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
CA2028925A1 (en)	1989-11-06	1991-05-07	Gerald R. Girard	Substituted n-(imidazolyl)alkyl alanine derivatives
FR2689508B1 (fr)	1992-04-01	1994-06-17	Fournier Ind & Sante	Derives de l'imidazole, leur procede de preparation et leur application en therapeutique.
JPH0687833A (ja) *	1992-07-21	1994-03-29	Sankyo Co Ltd	ビニルイミダゾール誘導体
EP1871764A1 (en)	2005-04-01	2008-01-02	LEK Pharmaceuticals D.D.	A synthesis of 4-bromomethyl-2'-formylbiphenyl and 4-bromomethyl-2'- hydroxymethylbiphenyl and its use in preparation of angiotensin ii antagonists
US20100216854A1 (en) *	2007-08-01	2010-08-26	Eldrug S.A.	1,3 and 1,3,5 substituted imidazoles as antihypertensives

2008
- 2008-05-23 WO PCT/IB2008/002184 patent/WO2008142576A2/en not_active Ceased
- 2008-05-23 BR BRPI0811264-9A2A patent/BRPI0811264A2/pt not_active Application Discontinuation
- 2008-05-23 JP JP2010508929A patent/JP2010527987A/ja active Pending
- 2008-05-23 AU AU2008252485A patent/AU2008252485A1/en not_active Abandoned
- 2008-05-23 KR KR1020097027055A patent/KR20100031113A/ko not_active Withdrawn
- 2008-05-23 CN CN200880100474.6A patent/CN101765590B/zh not_active Expired - Fee Related
- 2008-05-23 CA CA002687975A patent/CA2687975A1/en not_active Abandoned
- 2008-05-23 EP EP08789111.5A patent/EP2162441B1/en not_active Not-in-force
- 2008-05-23 RU RU2009148050/04A patent/RU2009148050A/ru unknown
- 2008-05-23 US US12/601,402 patent/US8563586B2/en not_active Expired - Fee Related
- 2008-05-23 MX MX2009012755A patent/MX2009012755A/es not_active Application Discontinuation
2009
- 2009-11-23 IL IL202293A patent/IL202293A0/en unknown

Also Published As

Publication number	Publication date
WO2008142576A3 (en)	2009-05-22
WO2008142576A2 (en)	2008-11-27
EP2162441A2 (en)	2010-03-17
CA2687975A1 (en)	2008-11-27
MX2009012755A (es)	2010-04-30
CN101765590B (zh)	2015-11-25
CN101765590A (zh)	2010-06-30
KR20100031113A (ko)	2010-03-19
AU2008252485A1 (en)	2008-11-27
EP2162441B1 (en)	2016-01-06
US20100166837A1 (en)	2010-07-01
JP2010527987A (ja)	2010-08-19
US8563586B2 (en)	2013-10-22
RU2009148050A (ru)	2011-06-27
IL202293A0 (en)	2010-06-16

Legal Events

Date	Code	Title
2015-06-02	B11A	Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
2015-09-01	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
2022-07-12	B350	Update of information on the portal [chapter 15.35 patent gazette]

Publication	Publication Date	Title
BRPI0813500A2 (pt)	2015-01-06	Compostos antivirais
BRPI0821086A2 (pt)	2014-10-07	Compostos inseticidas
DK2185567T3 (da)	2011-05-16	Substituerede bicyclolactam-forbindelser
BRPI0815042A2 (pt)	2015-02-10	Compostos de pirazol
EP2170350A4 (en)	2011-09-28	SUBSTITUTED IMIDAZOHETEROCYCLES
ATE542825T1 (de)	2012-02-15	Substituierte piperidino-dihydrothienopyrimidine
DK2288375T3 (da)	2012-05-21	Pegylerede insulin-lispro-forbindelser
BRPI0920707A2 (pt)	2015-12-29	compostos
DK2242759T3 (da)	2012-12-17	Forbindelser
ATE501136T1 (de)	2011-03-15	Imidazopyridinone
ATE514696T1 (de)	2011-07-15	Diphenyl-dihydro-imidazopyridinone
BRPI0809996A2 (pt)	2014-10-14	Compostos
BRPI0814424A2 (pt)	2015-01-06	Compostos heterociclila
BRPI0811451A2 (pt)	2014-11-04	Exopolissacarídeo
DK2323972T3 (da)	2013-10-07	C7-fluor-substituerede tetracylinforbindelser
DK2297162T3 (da)	2012-11-26	Forbindelser
BRPI0812840A2 (pt)	2014-12-09	2-imidazolinas
AT505058A3 (de)	2008-12-15	Türschliesssystem
BRPI0916432A2 (pt)	2016-02-16	compostos
BRPI0815181A2 (pt)	2015-03-31	Compostos
DK2206698T3 (da)	2012-08-27	Ethynylindolforbindelser
BRPI0814613A2 (pt)	2015-01-27	Compostos
LT3825306T (lt)	2023-08-10	Morfinano junginiai
BRPI0922152A2 (pt)	2015-08-18	Compostos
BRPI0922134A2 (pt)	2015-08-18	Compostos