BRPI0818560A2 - compostos orgânicos - Google Patents

compostos orgânicos

Info

Publication number: BRPI0818560A2
Authority: BR; Brazil
Prior art keywords: organic compounds; compounds; organic
Prior art date: 2007-10-12

Application number

BRPI0818560A

Other languages

English (en)

Inventor

Gomez-Mancilla Baltazar

Umbricht Daniel

Gasparini Fabrizio

Di Paolo Thérése

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-12

Filing date

2008-10-09

Publication date

2019-09-24

2008-10-09 Application filed by Novartis Ag filed Critical Novartis Ag

2019-09-24 Publication of BRPI0818560A2 publication Critical patent/BRPI0818560A2/pt

Links

150000002894 organic compounds Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Psychology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)

BRPI0818560A 2007-10-12 2008-10-09 compostos orgânicos BRPI0818560A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US97948607P	2007-10-12	2007-10-12
US5033308P	2008-05-05	2008-05-05
PCT/EP2008/063544 WO2009047296A2 (en)	2007-10-12	2008-10-09	Metabotropic glutamate receptor modulators for the treatment op parkinson's disease

Publications (1)

Publication Number	Publication Date
BRPI0818560A2 true BRPI0818560A2 (pt)	2019-09-24

Family

ID=40348021

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0818560A BRPI0818560A2 (pt)	2007-10-12	2008-10-09	compostos orgânicos

Country Status (19)

Country	Link
US (2)	US20100249136A1 (pt)
EP (1)	EP2211859B1 (pt)
JP (2)	JP5743545B2 (pt)
KR (1)	KR101572280B1 (pt)
CN (1)	CN101854935A (pt)
AU (1)	AU2008309621A1 (pt)
BR (1)	BRPI0818560A2 (pt)
CA (1)	CA2701853A1 (pt)
CL (1)	CL2008003006A1 (pt)
IL (1)	IL204954A0 (pt)
MA (1)	MA31798B1 (pt)
MX (1)	MX2010003913A (pt)
NZ (1)	NZ584856A (pt)
RU (1)	RU2508107C2 (pt)
SG (1)	SG185293A1 (pt)
TN (1)	TN2010000155A1 (pt)
TW (1)	TW200924745A (pt)
WO (1)	WO2009047296A2 (pt)
ZA (1)	ZA201002423B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2320892A2 (en) *	2008-06-30	2011-05-18	Novartis AG	Combination products
EP2315748B1 (en) *	2008-08-12	2015-06-24	Novartis AG	Processes for the preparation of 4-oxo-octahydro-indole-1-carbocylic acid methyl ester and derivatives thereof
US8796295B2 (en)	2009-09-17	2014-08-05	Vanderbilt University	Substituted benzamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same
EP2680849A4 (en) *	2011-03-03	2015-02-18	Univ Vanderbilt	6-ALKYL-N- (PYRIDIN-2-YL) -4-ARYLOXYPICOLINAMIDE ANALOGUE AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHOD FOR THEIR PREPARATION AND USE
MX2013010698A (es)	2011-03-18	2014-02-17	Novartis Ag	Combinaciones de activadores del receptor de acetil-colina nicotinico alfa-7 y antagonistas del receptor de glutamato metabotropico 5 (mglur5) para usarse en la discinesia inducida por dopamina en la enfermedad de parkinson.
GB201204962D0 (en)	2012-03-21	2012-05-02	Addex Pharmaceuticals Sa	Pharmaceutical combination products for parkinsons disease
CA2931097A1 (en)	2013-11-19	2015-05-28	Vanderbilt University	Substituted imidazopyridine and triazolopyridine compounds as negative allosteric modulators of mglur5
US9533982B2 (en)	2014-03-20	2017-01-03	Vanderbilt University	Substituted bicyclic heteroaryl carboxamide analogs as mGluR5 negative allosteric modulators
US9550778B2 (en)	2014-10-03	2017-01-24	Vanderbilt University	Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5
KR101749675B1 (ko) *	2015-07-20	2017-06-26	동국대학교 산학협력단	멜라닌 응집 호르몬을 유효성분으로 포함하는 파킨슨병 치료 및 레보도파 부작용 억제용 약학 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6379666B1 (en) *	1999-02-24	2002-04-30	Edward L. Tobinick	TNF inhibitors for the treatment of neurological, retinal and muscular disorders
HK1048635A1 (zh) *	1999-06-02	2003-04-11	Nps药物有限公司	代谢移变的谷氨酸盐受体拮抗剂和它们治疗中枢神经系统疾病的用途
GB0128996D0 (en) *	2001-12-04	2002-01-23	Novartis Ag	Organic compounds
US7105548B2 (en) *	2001-12-18	2006-09-12	Merck & Co., Inc.	Heteroaryl substituted triazole modulators of metabotropic glutamate receptor-5
EP1539749A4 (en) *	2002-09-13	2007-06-13	Merck & Co Inc	BY CONDENSED HETEROBICYCLOGRUPPEN SUBSTITUTED PHENYL COMPOUNDS AS METOBOTROPE GLUTAMATE-5 MODULATORS
WO2004069146A2 (en) *	2003-02-07	2004-08-19	Yissum Research Development Company Of The Hebrew University Of Jerusalem	L-dopa amide derivatives and uses thereof
JP2007506741A (ja) *	2003-09-23	2007-03-22	メルク　エンド　カムパニー　インコーポレーテッド	向代謝性グルタミン酸受容体のピラゾール系調節剤
JP2007524682A (ja) *	2004-02-12	2007-08-30	メルク　エンド　カムパニー　インコーポレーテッド	代謝調節型グルタミン酸受容体−５の調節物質としてのビピリジルアミド
CN101133027B (zh) *	2005-03-04	2011-03-30	弗·哈夫曼-拉罗切有限公司	作为mglur5拮抗剂的吡啶-2-甲酰胺衍生物
GB0508319D0 (en) *	2005-04-25	2005-06-01	Novartis Ag	Organic compounds
GB0508318D0 (en) *	2005-04-25	2005-06-01	Novartis Ag	Organic compounds
TW200801005A (en) *	2005-08-15	2008-01-01	Astrazeneca Ab	Acetylenic piperazines as metabotropic glutamate receptor antagonists
KR20080076962A (ko) *	2005-12-20	2008-08-20	노파르티스 아게	대사성 글루타메이트 수용체 조절제로서의 니코틴산 유도체
MX2009002684A (es) *	2006-09-11	2009-06-05	Novartis Ag	Derivados de acido nicotinico como moduladores de receptores de glutamato metabotropico.
EP2320892A2 (en) *	2008-06-30	2011-05-18	Novartis AG	Combination products

2008
- 2008-10-09 RU RU2010118454/15A patent/RU2508107C2/ru not_active IP Right Cessation
- 2008-10-09 KR KR1020107010331A patent/KR101572280B1/ko not_active Expired - Fee Related
- 2008-10-09 MX MX2010003913A patent/MX2010003913A/es active IP Right Grant
- 2008-10-09 WO PCT/EP2008/063544 patent/WO2009047296A2/en not_active Ceased
- 2008-10-09 AU AU2008309621A patent/AU2008309621A1/en not_active Abandoned
- 2008-10-09 CN CN200880110746A patent/CN101854935A/zh active Pending
- 2008-10-09 CA CA2701853A patent/CA2701853A1/en not_active Abandoned
- 2008-10-09 JP JP2010528396A patent/JP5743545B2/ja not_active Expired - Fee Related
- 2008-10-09 US US12/682,624 patent/US20100249136A1/en not_active Abandoned
- 2008-10-09 NZ NZ584856A patent/NZ584856A/xx not_active IP Right Cessation
- 2008-10-09 EP EP08805185.9A patent/EP2211859B1/en not_active Not-in-force
- 2008-10-09 SG SG2012075677A patent/SG185293A1/en unknown
- 2008-10-09 BR BRPI0818560A patent/BRPI0818560A2/pt not_active IP Right Cessation
- 2008-10-09 TW TW097139070A patent/TW200924745A/zh unknown
- 2008-10-10 CL CL2008003006A patent/CL2008003006A1/es unknown
2010
- 2010-04-07 ZA ZA2010/02423A patent/ZA201002423B/en unknown
- 2010-04-08 IL IL204954A patent/IL204954A0/en unknown
- 2010-04-12 TN TN2010000155A patent/TN2010000155A1/fr unknown
- 2010-04-30 MA MA32804A patent/MA31798B1/fr unknown
2014
- 2014-08-29 JP JP2014175983A patent/JP2014240425A/ja active Pending
2015
- 2015-06-11 US US14/736,901 patent/US20150272929A1/en not_active Abandoned

Also Published As

Publication number	Publication date
TW200924745A (en)	2009-06-16
US20100249136A1 (en)	2010-09-30
US20150272929A1 (en)	2015-10-01
KR101572280B1 (ko)	2015-11-26
EP2211859A2 (en)	2010-08-04
SG185293A1 (en)	2012-11-29
MA31798B1 (fr)	2010-10-01
NZ584856A (en)	2012-12-21
JP5743545B2 (ja)	2015-07-01
JP2011500529A (ja)	2011-01-06
RU2508107C2 (ru)	2014-02-27
CL2008003006A1 (es)	2009-05-08
RU2010118454A (ru)	2011-11-20
CA2701853A1 (en)	2009-04-16
TN2010000155A1 (en)	2011-11-11
JP2014240425A (ja)	2014-12-25
ZA201002423B (en)	2010-12-29
AU2008309621A1 (en)	2009-04-16
WO2009047296A2 (en)	2009-04-16
WO2009047296A3 (en)	2009-08-20
IL204954A0 (en)	2010-11-30
EP2211859B1 (en)	2016-01-06
KR20100088136A (ko)	2010-08-06
MX2010003913A (es)	2010-04-27
CN101854935A (zh)	2010-10-06

Legal Events

Date	Code	Title	Description
2019-10-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2020-01-21	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
DK2240490T3 (da)	2013-12-16	Organiske forbindelser
BRPI0817434A2 (pt)	2015-06-16	Composto orgânicos
BRPI0811562A2 (pt)	2014-12-09	Compostos orgânicos
BRPI0922351A2 (pt)	2018-06-05	compostos orgânicos
BRPI0922700A2 (pt)	2015-08-11	Compostos orgânicos
BRPI0922808A2 (pt)	2018-05-29	compostos orgânicos
BRPI0922348A2 (pt)	2015-08-11	Compostos orgânicos
BRPI0922809A2 (pt)	2018-05-29	compostos orgânicos
BRPI0922131A2 (pt)	2015-08-18	Compostos orgânicos
BRPI0913966A2 (pt)	2015-11-17	compostos orgânicos
BRPI0914698A2 (pt)	2015-10-20	compostos orgânicos
BRPI0909417A2 (pt)	2015-12-08	compostos orgânicos
BRPI0915018A2 (pt)	2015-10-27	compostos orgânicos
BRPI0718874A2 (pt)	2015-06-23	Compostos orgânicos
NO20084803L (no)	2008-11-19	organiske forbindelser
BRPI0718478A2 (pt)	2013-11-26	Compostos orgânicos
DK2310359T3 (da)	2014-04-07	Organiske forbindelser
BRPI0917574A2 (pt)	2015-11-17	compostos orgânicos
BRPI0921826A2 (pt)	2016-01-12	compostos orgânicos
BRPI0907611A2 (pt)	2015-07-21	Compostos orgânicos
BRPI0821401A2 (pt)	2014-10-14	Compostos orgânicos
BRPI0813500A2 (pt)	2015-01-06	Compostos antivirais
ATE502948T1 (de)	2011-04-15	Substituierte bicyclolactamverbindungen
BRPI0821086A2 (pt)	2014-10-07	Compostos inseticidas
BRPI0712902A2 (pt)	2018-10-30	compostos orgânicos