BRPI0821401A2 - Compostos orgânicos - Google Patents

Compostos orgânicos

Info

Publication number
BRPI0821401A2
BRPI0821401A2 BRPI0821401-8A2A BRPI0821401A BRPI0821401A2 BR PI0821401 A2 BRPI0821401 A2 BR PI0821401A2 BR PI0821401 A BRPI0821401 A BR PI0821401A BR PI0821401 A2 BRPI0821401 A2 BR PI0821401A2
Authority
BR
Brazil
Prior art keywords
organic compounds
compounds
organic
Prior art date
Application number
BRPI0821401-8A2A
Other languages
English (en)
Inventor
Yehuda G Assaraf
Thomas Jostock
Hans-Peter Knopf
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0821401A2 publication Critical patent/BRPI0821401A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1079Screening libraries by altering the phenotype or phenotypic trait of the host
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BRPI0821401-8A2A 2007-12-21 2008-12-19 Compostos orgânicos BRPI0821401A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07150326 2007-12-21
PCT/EP2008/068046 WO2009080759A1 (en) 2007-12-21 2008-12-19 Organic compounds

Publications (1)

Publication Number Publication Date
BRPI0821401A2 true BRPI0821401A2 (pt) 2014-10-14

Family

ID=39560901

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821401-8A2A BRPI0821401A2 (pt) 2007-12-21 2008-12-19 Compostos orgânicos

Country Status (15)

Country Link
US (5) US20100330572A1 (pt)
EP (1) EP2227549B1 (pt)
JP (2) JP5660900B2 (pt)
KR (1) KR101706390B1 (pt)
CN (2) CN101903526B (pt)
AU (1) AU2008340017B2 (pt)
BR (1) BRPI0821401A2 (pt)
CA (1) CA2709503C (pt)
DK (1) DK2227549T3 (pt)
ES (1) ES2546086T3 (pt)
IL (1) IL206233A (pt)
PL (1) PL2227549T3 (pt)
PT (1) PT2227549E (pt)
RU (1) RU2502802C2 (pt)
WO (1) WO2009080759A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011009025A (es) 2009-02-27 2011-09-28 Novartis Ag Sistema de vector de expresion que comprende dos marcadores de seleccion.
KR20230044026A (ko) 2010-02-24 2023-03-31 이뮤노젠 아이엔씨 엽산염 수용체 1 항체와 면역접합체 및 이들의 용도
EA201791843A3 (ru) 2011-04-01 2018-05-31 Иммьюноджен, Инк. Способы повышения эффективности folr1 терапии рака
EP2890717B1 (en) 2012-08-31 2020-03-04 ImmunoGen, Inc. Diagnostic assays and kits for detection of folate receptor 1
JP6388592B2 (ja) 2012-11-20 2018-09-12 ノバルティス アーゲー ポリペプチドを高収量で発現するための最適化発現カセット
EP2970956A1 (en) 2013-03-11 2016-01-20 Novartis AG Method of screening cell clones
AU2014297966B2 (en) 2013-07-31 2017-10-26 Novartis Ag Novel selection vectors and methods of selecting eukaryotic host cells
IL244061B (en) 2013-08-30 2022-07-01 Immunogen Inc Antibodies and assays for the detection of folate receptor 1
EP3083677B1 (en) 2013-12-20 2019-08-28 Novartis AG Novel eukaryotic cells and methods for recombinantly expressing a product of interest
WO2015092735A1 (en) 2013-12-20 2015-06-25 Novartis Ag Novel eukaryotic cells and methods for recombinantly expressing a product of interest
KR102307278B1 (ko) 2014-04-29 2021-09-30 노파르티스 아게 신규 척추동물 세포 및 관심 폴리펩티드의 재조합적 발현 방법
LT3277818T (lt) * 2015-04-03 2020-02-25 Selexis S.A. Vitaminų, vitaminų metabolizmo genų ir baltymų panaudojimas rekombinantinių baltymų gamybai žinduolių ląstelėse
CN108135902A (zh) * 2015-07-30 2018-06-08 爱科谱迅病理研究公司 用于最优癌症治疗的定量FR-α和GART蛋白质
AU2016323968B2 (en) 2015-09-17 2023-07-06 Immunogen, Inc. Therapeutic combinations comprising anti-FOLR1 immunoconjugates
WO2019070638A1 (en) 2017-10-02 2019-04-11 Astrazeneca Ab CELL LINES AND METHODS FOR INCREASED PROTEIN PRODUCTION
WO2022107090A1 (en) 2020-11-23 2022-05-27 Novartis Ag Expression technology for antibody constructs
US20240239871A1 (en) 2021-04-29 2024-07-18 Novartis Ag Hypersialylating cells
CN118985647A (zh) * 2024-08-13 2024-11-22 杭州卓智康悦科技有限公司 一种净化空气释放负离子的中药抑菌液及制备工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0555203B1 (en) * 1988-12-08 1995-10-18 Abbott Laboratories Expression induction method employing dhfr gene
IL116872A (en) * 1995-02-15 2004-12-15 Aventis Pharma Sa Delta-5, 7 sterol reductase from arabidopsis thaliana
JP5171033B2 (ja) * 2003-03-11 2013-03-27 メルク セローノ ソシエテ アノニム mCMVIE2プロモーターを含んで成る発現ベクター
IL165484A0 (en) 2004-11-30 2006-01-15 Applied Research Systems Production of proteins
CN100567482C (zh) * 2006-10-12 2009-12-09 南开大学 高效表达rhBMP2的CHO细胞株及其建立方法

Also Published As

Publication number Publication date
EP2227549B1 (en) 2015-06-17
AU2008340017A1 (en) 2009-07-02
US20140295489A1 (en) 2014-10-02
KR20100111698A (ko) 2010-10-15
CA2709503A1 (en) 2009-07-02
IL206233A0 (en) 2010-12-30
CN103805633B (zh) 2016-09-07
JP5660900B2 (ja) 2015-01-28
CN101903526A (zh) 2010-12-01
PL2227549T3 (pl) 2015-12-31
US20160355828A1 (en) 2016-12-08
ES2546086T3 (es) 2015-09-18
CA2709503C (en) 2016-07-12
US10767186B2 (en) 2020-09-08
US20100330572A1 (en) 2010-12-30
US20200370055A1 (en) 2020-11-26
WO2009080759A1 (en) 2009-07-02
EP2227549A1 (en) 2010-09-15
IL206233A (en) 2015-10-29
CN101903526B (zh) 2014-02-12
RU2010129550A (ru) 2012-01-27
JP2014236745A (ja) 2014-12-18
CN103805633A (zh) 2014-05-21
KR101706390B1 (ko) 2017-02-13
RU2502802C2 (ru) 2013-12-27
DK2227549T3 (en) 2015-09-21
JP2011505861A (ja) 2011-03-03
US20120276579A1 (en) 2012-11-01
JP6002183B2 (ja) 2016-10-05
PT2227549E (pt) 2015-10-08
AU2008340017B2 (en) 2012-04-05

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]