BRPI0818764A2 - Célula para uso na produção de heteroproteínas e processo de produção utilizando a mesma. - Google Patents

Célula para uso na produção de heteroproteínas e processo de produção utilizando a mesma.

Info

Publication number
BRPI0818764A2
BRPI0818764A2 BRPI0818764A BRPI0818764A2 BR PI0818764 A2 BRPI0818764 A2 BR PI0818764A2 BR PI0818764 A BRPI0818764 A BR PI0818764A BR PI0818764 A2 BRPI0818764 A2 BR PI0818764A2
Authority
BR
Brazil
Prior art keywords
production
heteroprotein
cell
production process
heteroprotein production
Prior art date
Application number
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Satoshi Tainaka
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0818764A2 publication Critical patent/BRPI0818764A2/pt
Publication of BRPI0818764B1 publication Critical patent/BRPI0818764B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0818764-9A 2007-10-24 2008-10-23 Process of production of a polipeptídeo BRPI0818764B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007276182 2007-10-24
JP2007-276182 2007-10-24
PCT/JP2008/069184 WO2009054433A1 (ja) 2007-10-24 2008-10-23 異種タンパク質製造のための細胞及びそれを用いた製造方法

Publications (2)

Publication Number Publication Date
BRPI0818764A2 true BRPI0818764A2 (pt) 2015-04-22
BRPI0818764B1 BRPI0818764B1 (pt) 2017-11-21

Family

ID=40579535

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818764-9A BRPI0818764B1 (pt) 2007-10-24 2008-10-23 Process of production of a polipeptídeo

Country Status (14)

Country Link
US (1) US9068212B2 (pt)
EP (1) EP2213746B1 (pt)
JP (1) JP5337044B2 (pt)
KR (1) KR101636086B1 (pt)
CN (1) CN101821403B (pt)
AU (1) AU2008314973C1 (pt)
BR (1) BRPI0818764B1 (pt)
CA (1) CA2703493C (pt)
DK (1) DK2213746T3 (pt)
ES (1) ES2548294T3 (pt)
MX (1) MX2010004397A (pt)
RU (1) RU2494148C2 (pt)
TW (1) TWI434935B (pt)
WO (1) WO2009054433A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007239679B2 (en) 2006-04-13 2012-10-11 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
JP5635260B2 (ja) 2007-03-15 2014-12-03 中外製薬株式会社 ポリペプチドの製造方法
KR101577839B1 (ko) 2007-08-07 2015-12-15 추가이 세이야쿠 가부시키가이샤 이종 단백질의 제조 방법
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
ES2548294T3 (es) 2007-10-24 2015-10-15 Chugai Seiyaku Kabushiki Kaisha Célula para su uso en la producción de proteína exógena, y procedimiento de producción usando la célula
EP2423309B1 (en) * 2009-04-22 2018-01-03 Chugai Seiyaku Kabushiki Kaisha A method for producing a cell capable of high-yield production of heteroproteins
WO2012118848A1 (en) 2011-02-28 2012-09-07 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
BR112013024781B1 (pt) 2011-04-01 2021-09-08 Chugai Seiyaku Kabushiki Kaisha Métodos de produção de um anticorpo e de uma composição farmacêutica
US9675171B2 (en) * 2012-10-05 2017-06-13 Lamplight Farms Incorporated Outdoor appliance with retractable platform
CN112522353A (zh) * 2012-10-10 2021-03-19 中外制药株式会社 经修饰的宿主细胞的建立方法
MX383347B (es) * 2014-08-11 2025-03-13 Hoffmann La Roche Método para incrementar la velocidad de producción específica de células eucariotas.
CN107287178B (zh) * 2016-04-12 2019-10-29 中国科学院微生物研究所 Csad蛋白及其编码基因在抗流感病毒中的应用
WO2020122049A1 (ja) * 2018-12-11 2020-06-18 富士フイルム株式会社 動物細胞、動物細胞の製造方法および目的タンパク質の製造方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59184841A (ja) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− サンプル中の白血球のサブクラスを識別する方法および装置
GB9019812D0 (en) * 1990-09-11 1990-10-24 Scotgen Ltd Novel antibodies for treatment and prevention of infection in animals and man
WO1993018143A1 (en) 1992-03-04 1993-09-16 Synaptic Pharmaceutical Corporation Dna encoding taurine and gaba transporters and uses thereof
US6225115B1 (en) 1992-03-04 2001-05-01 Synaptic Pharmaceutical Corporation DNA encoding taurine and GABA transporters and uses thereof
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
JP3630453B2 (ja) 1994-09-30 2005-03-16 中外製薬株式会社 Ｉｌ−６レセプター抗体を有効成分とする未熟型骨髄腫細胞治療剤
AU695117B2 (en) 1994-10-06 1998-08-06 Hoechst Aktiengesellschaft Regulated genes by stimulation of chondrocytes with IL-1beta
JPH09203734A (ja) 1996-01-26 1997-08-05 Sumitomo Electric Ind Ltd 抗血清、抗体、リガンド及びそれらの検出方法
JPH1075787A (ja) 1996-09-02 1998-03-24 Asahi Chem Ind Co Ltd 変異型アラニンアミノトランスフェラーゼおよびその製造法
JPH10191984A (ja) 1997-01-09 1998-07-28 Oriental Yeast Co Ltd 活性型ヒトａｌｔの製造法
DE19855313A1 (de) 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen
US7413536B1 (en) 1999-09-14 2008-08-19 Xenoport, Inc. Substrates and screening methods for transport proteins
US6812339B1 (en) 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
AU2002308701A1 (en) 2001-05-14 2002-11-25 University Of Maryland, Baltimore Novel alanine transaminase enzyme and methods of use
IL161677A0 (en) 2001-11-08 2004-09-27 Protein Design Labs Stable liquid pharmaceutical formulation of igg antibodies
DE60327804D1 (de) 2002-01-18 2009-07-09 Novozymes As Alanin-2,3-aminomutase
US20050265983A1 (en) 2002-11-17 2005-12-01 Eldad Melamed Methods, nucleic acid constructs and cells for treating neurodegenerative disorders
IL152905A0 (en) 2002-11-17 2003-06-24 Univ Ramot Dopaminergic markers induction in neuronal-like cells isolated from adult human bone marrow stromal cells: implications for novel gene therapy strategy for parkinsons disease
US20030165495A1 (en) 2003-04-01 2003-09-04 Carulli John P. Nucleic acids and polypeptides
US20050170391A1 (en) 2004-01-30 2005-08-04 Xenoport, Inc. TAUT1 transporters expressed in blood brain barrier cells
KR100789645B1 (ko) 2004-04-14 2007-12-27 주식회사유한양행 Ｂ형 간염바이러스의 ｓ-표면항원을 인식하는 인간화 항체및 이의 제조방법
SI1674111T1 (sl) 2004-07-09 2011-02-28 Chugai Pharmaceutical Co Ltd Protitelo proti glipikanu 3
WO2006038315A1 (ja) 2004-10-07 2006-04-13 Kabushiki Kaisha Sangi 経皮・経粘膜吸収製剤
JO3058B1 (ar) 2005-04-29 2017-03-15 Applied Molecular Evolution Inc الاجسام المضادة لمضادات -اي ال-6,تركيباتها طرقها واستعمالاتها
JP5364378B2 (ja) * 2005-11-09 2013-12-11 アボット・ラボラトリーズ ヒトｂｎｐ免疫特異的抗体
AU2006330817B2 (en) 2005-12-23 2012-07-19 Arcadia Biosciences, Inc. Nitrogen-efficient monocot plants
AU2007239679B2 (en) 2006-04-13 2012-10-11 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
JP5635260B2 (ja) 2007-03-15 2014-12-03 中外製薬株式会社 ポリペプチドの製造方法
KR101577839B1 (ko) 2007-08-07 2015-12-15 추가이 세이야쿠 가부시키가이샤 이종 단백질의 제조 방법
WO2009051109A1 (ja) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質を高生産する細胞の作製方法
ES2548294T3 (es) 2007-10-24 2015-10-15 Chugai Seiyaku Kabushiki Kaisha Célula para su uso en la producción de proteína exógena, y procedimiento de producción usando la célula
EP2423309B1 (en) 2009-04-22 2018-01-03 Chugai Seiyaku Kabushiki Kaisha A method for producing a cell capable of high-yield production of heteroproteins

Also Published As

Publication number Publication date
TWI434935B (zh) 2014-04-21
EP2213746A1 (en) 2010-08-04
CN101821403B (zh) 2014-01-01
KR101636086B1 (ko) 2016-07-04
US20110014654A1 (en) 2011-01-20
AU2008314973B2 (en) 2014-01-09
CA2703493A1 (en) 2009-04-30
WO2009054433A1 (ja) 2009-04-30
EP2213746B1 (en) 2015-07-15
US9068212B2 (en) 2015-06-30
RU2494148C2 (ru) 2013-09-27
AU2008314973C1 (en) 2014-05-08
AU2008314973A1 (en) 2009-04-30
CN101821403A (zh) 2010-09-01
JP5337044B2 (ja) 2013-11-06
CA2703493C (en) 2016-11-08
DK2213746T3 (en) 2015-08-03
EP2213746A4 (en) 2010-11-24
BRPI0818764B1 (pt) 2017-11-21
TW200934870A (en) 2009-08-16
KR20100082003A (ko) 2010-07-15
JPWO2009054433A1 (ja) 2011-03-03
HK1143404A1 (en) 2010-12-31
RU2010120677A (ru) 2011-11-27
MX2010004397A (es) 2010-06-01
ES2548294T3 (es) 2015-10-15

Similar Documents

Publication Publication Date Title
BRPI0818764A2 (pt) Célula para uso na produção de heteroproteínas e processo de produção utilizando a mesma.
BRPI0906957A2 (pt) Aerogéis de carbono, processo para a sua preparação e seu uso
BRPI0816807A2 (pt) bortezomib e processo para a produção do mesmo
PT2041259E (pt) Processo melhorado para a cultura de células
BRPI0907909A2 (pt) Sistema, e, processo para a produção e uso do mesmo
BRPI0820733A2 (pt) Processo para a preparação de macrociclo
BRPI0812481A2 (pt) Composição aquosa, processo para a fabricação da composição aquosa, uso da composição aquosa, e, processo para a produção de epicloridrina
BRPI0814221A2 (pt) Fibra de enchimento comportamento de abertura aprimorado, processo para a sua produção e seu uso
BRPI0812712A2 (pt) produto, processo para produzir o produto, e, uso do produto
BRPI0814611A2 (pt) Composição, processo para preparar uma composição, e, uso de uma composição
BRPI0819986A2 (pt) ferramenta de poço para uso em um furo de poço
BRPI0814272A2 (pt) Carbono quimicamente ativado, processo para a produção de um carbono quimicamente ativado, e, uso de um carbono ativado
BRPI0812054A2 (pt) Processo para preparar compostos, e, compostos.
BRPI0822660A2 (pt) Copolímero de enxerto, processo para a preparação do mesmo e seu uso
BRPI0718268A2 (pt) Eletrodo frontal para uso em dispositivo fotovoltaico e processo de produção do mesmo.
BRPI0721404A2 (pt) Moldagem, composição de moldagem, processo para produção de moldagens e uso da mesma
BRPI0816478A2 (pt) Processo para produção de celulases
BRPI0809681A2 (pt) processo para fabricação de polímeros
BRPI0813660A2 (pt) Processo para o cultivo de microalgas
BRPI0816349A2 (pt) sistema, sistema para uso em um poço, e método
BRPI0822858A2 (pt) Processo de estação para fabricação de um cartucho de aparelho de barbear ou depilar e cartucho de aparelho de barbear ou depilar.
BRPI0810842A2 (pt) Processo para a carbonilação de dimetil éter
BRPI0813371A2 (pt) Rolo para uso na fabricação de chapa de vidro.
BRPI0807864A2 (pt) Complexo cristalino, processo para a preparação do complexo cristalino, e, composição agrícola
BRPI0807910A2 (pt) Processo para produzir celulose não-cristalina

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 12A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2600 DE 03-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.