BRPI0819307A2 - Polimorfos de um inibidor do c-met/hgfr - Google Patents

Polimorfos de um inibidor do c-met/hgfr

Info

Publication number
BRPI0819307A2
BRPI0819307A2 BRPI0819307A BRPI0819307A2 BR PI0819307 A2 BRPI0819307 A2 BR PI0819307A2 BR PI0819307 A BRPI0819307 A BR PI0819307A BR PI0819307 A2 BRPI0819307 A2 BR PI0819307A2
Authority
BR
Brazil
Prior art keywords
polymorphs
met
hgfr inhibitor
hgfr
inhibitor
Prior art date
Application number
Other languages
English (en)
Inventor
Benjamin Micah Collman
Jingrong Jean Cui
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0819307A2 publication Critical patent/BRPI0819307A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0819307 2007-11-29 2008-11-18 Polimorfos de um inibidor do c-met/hgfr BRPI0819307A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99116907P 2007-11-29 2007-11-29
PCT/IB2008/003170 WO2009068955A2 (en) 2007-11-29 2008-11-18 Polymorphs of a c-met/hgfr inhibitor

Publications (1)

Publication Number Publication Date
BRPI0819307A2 true BRPI0819307A2 (pt) 2015-05-12

Family

ID=40405077

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819307 BRPI0819307A2 (pt) 2007-11-29 2008-11-18 Polimorfos de um inibidor do c-met/hgfr

Country Status (15)

Country Link
US (1) US20110039856A1 (pt)
EP (1) EP2227473A2 (pt)
JP (1) JP2009132714A (pt)
KR (1) KR20100085142A (pt)
CN (1) CN101878215A (pt)
AR (1) AR069491A1 (pt)
AU (1) AU2008331278A1 (pt)
BR (1) BRPI0819307A2 (pt)
CA (1) CA2706430A1 (pt)
IL (1) IL205756A0 (pt)
MX (1) MX2010005867A (pt)
RU (1) RU2446168C2 (pt)
TW (1) TW200927120A (pt)
WO (1) WO2009068955A2 (pt)
ZA (1) ZA201004027B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012042421A1 (en) 2010-09-29 2012-04-05 Pfizer Inc. Method of treating abnormal cell growth
WO2013038362A1 (en) 2011-09-15 2013-03-21 Novartis Ag 6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
US9994574B2 (en) * 2012-11-12 2018-06-12 Victoria Link Limited Salt and polymorphic forms of (3R,4S)-L-((4-amino-5H-pyrrolo[3,2,-d]pyrimidin-7-yl)methyl)-4(methylthiomethyl)pyrodin-3-ol(MTDIA)
CN105367588B (zh) * 2015-12-09 2018-09-11 上海宣创生物科技有限公司 一种三唑并吡嗪衍生物c晶型及其制备方法
CN106928232B (zh) * 2015-12-31 2019-07-09 上海医药集团股份有限公司 喹啉类化合物及其盐的晶型、制备方法、组合物与应用
CN108570053A (zh) * 2017-03-13 2018-09-25 中国科学院上海药物研究所 五元并六元杂环化合物、制备方法、中间体、组合和应用
UY37634A (es) * 2017-03-17 2018-10-31 Dow Agrosciences Llc Composiciones de inhibidores de la nitrificación microencapsulados
JP2022513215A (ja) * 2018-12-14 2022-02-07 ベータ・ファーマ・インコーポレイテッド C-met阻害剤としての有機リン置換化合物およびその治療用途
MX2021009863A (es) 2019-03-21 2021-11-12 Onxeo Una molecula dbait en combinacion con inhibidor de quinasa para el tratamiento del cancer.
EP4054579A1 (en) 2019-11-08 2022-09-14 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for the treatment of cancers that have acquired resistance to kinase inhibitors
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2000613C2 (nl) * 2006-05-11 2007-11-20 Pfizer Prod Inc Triazoolpyrazinederivaten.

Also Published As

Publication number Publication date
TW200927120A (en) 2009-07-01
IL205756A0 (en) 2010-11-30
MX2010005867A (es) 2010-06-11
JP2009132714A (ja) 2009-06-18
CN101878215A (zh) 2010-11-03
WO2009068955A3 (en) 2010-05-27
CA2706430A1 (en) 2009-06-04
KR20100085142A (ko) 2010-07-28
RU2010121647A (ru) 2011-12-10
EP2227473A2 (en) 2010-09-15
WO2009068955A2 (en) 2009-06-04
AR069491A1 (es) 2010-01-27
US20110039856A1 (en) 2011-02-17
AU2008331278A1 (en) 2009-06-04
ZA201004027B (en) 2011-03-30
RU2446168C2 (ru) 2012-03-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.