BRPI0819849B8 - sistemas de solvente para formulações pour on para combater parasitas - Google Patents

sistemas de solvente para formulações pour on para combater parasitas

Info

Publication number
BRPI0819849B8
BRPI0819849B8 BRPI0819849A BRPI0819849A BRPI0819849B8 BR PI0819849 B8 BRPI0819849 B8 BR PI0819849B8 BR PI0819849 A BRPI0819849 A BR PI0819849A BR PI0819849 A BRPI0819849 A BR PI0819849A BR PI0819849 B8 BRPI0819849 B8 BR PI0819849B8
Authority
BR
Brazil
Prior art keywords
formulations
pour
animals
solvent systems
combat
Prior art date
Application number
BRPI0819849A
Other languages
English (en)
Inventor
Cleverly Douglas
David Soll Mark
Thwaites Paul
Peter Gogolewski Ronald
Original Assignee
Merial Ltd
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Merial Inc filed Critical Merial Ltd
Publication of BRPI0819849A2 publication Critical patent/BRPI0819849A2/pt
Publication of BRPI0819849B1 publication Critical patent/BRPI0819849B1/pt
Publication of BRPI0819849B8 publication Critical patent/BRPI0819849B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Environmental Sciences (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Inorganic Chemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

sistemas de solvente para formulaçoes pour on para combater parasitas. esta invenção se refere às formuiações farmacêuticas e veterinárias que proporcionam solvência e estabilidade melhorada para agentes farmacêuticos e veterinátios para administração aos animais, especialmente ruminantes. além disso, a invenção se refere às formulações pour on para combater parasitas em animais, como gado e ovelha. em algumas modalidades, esta invenção fornece formulações pour on à base de éter glicólico compreendendo uma composição compreendendo um fasciolicida, tal como, por exemplo, clorsulon (4-amino-6-tricloroetenil-1, 3- benzenodissulfonamida) e/ou um macrolideo antielmíntico ou agente antiparasítico. em outras modalidades, a invenção fornece formulaçães pour on compreendendo pelo menos um agente ativo, um éter glicólico e um intensificador de estabilidade. esta invenção também proporciona métodos para a erradicação, controle e/ou prevenção de infestação por parasita em animais, como gado e ovelhas.
BRPI0819849A 2007-11-26 2008-11-26 sistemas de solvente para formulações pour on para combater parasitas BRPI0819849B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99020507P 2007-11-26 2007-11-26
US60/990,205 2007-11-26
PCT/US2008/084884 WO2009070687A1 (en) 2007-11-26 2008-11-26 Solvent systems for pour-on formulations for combating parasites

Publications (3)

Publication Number Publication Date
BRPI0819849A2 BRPI0819849A2 (pt) 2016-10-11
BRPI0819849B1 BRPI0819849B1 (pt) 2021-01-05
BRPI0819849B8 true BRPI0819849B8 (pt) 2021-05-25

Family

ID=40678982

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819849A BRPI0819849B8 (pt) 2007-11-26 2008-11-26 sistemas de solvente para formulações pour on para combater parasitas

Country Status (14)

Country Link
US (1) US8097266B2 (pt)
EP (1) EP2222168B1 (pt)
JP (1) JP5513403B2 (pt)
CN (1) CN101909450B (pt)
AU (1) AU2008329706B2 (pt)
BR (1) BRPI0819849B8 (pt)
CA (1) CA2706448C (pt)
DK (1) DK2222168T3 (pt)
ES (1) ES2693696T3 (pt)
MX (1) MX2010005685A (pt)
NZ (1) NZ585499A (pt)
RU (1) RU2497364C2 (pt)
WO (1) WO2009070687A1 (pt)
ZA (1) ZA201003581B (pt)

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CN102845416B (zh) * 2011-07-01 2016-08-03 大日本除虫菊株式会社 芳香性防虫驱虫剂
BRPI1104180A2 (pt) * 2011-08-25 2013-08-13 Eurofarma Lab Ltda composiÇÕes veterinÁrias pour on nço residuais, uso, kit, e mÉtodo de tratamento de parasitoses
CA2855954C (en) * 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
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CN114903848A (zh) * 2013-02-27 2022-08-16 阿根塔创新有限公司 透皮制剂
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HK1220632A1 (zh) * 2013-09-20 2017-05-12 参天制药株式会社 含有聚乙二醇的组合物
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AR113997A1 (es) * 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
AR116524A1 (es) * 2018-10-04 2021-05-19 Elanco Tiergesundheit Ag Potenciación de tratamiento de helmintos
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Also Published As

Publication number Publication date
US20090163575A1 (en) 2009-06-25
CN101909450B (zh) 2014-04-23
EP2222168B1 (en) 2018-09-12
NZ585499A (en) 2011-12-22
CN101909450A (zh) 2010-12-08
MX2010005685A (es) 2010-09-28
RU2010126173A (ru) 2012-01-10
US8097266B2 (en) 2012-01-17
CA2706448A1 (en) 2009-06-04
JP5513403B2 (ja) 2014-06-04
BRPI0819849A2 (pt) 2016-10-11
CA2706448C (en) 2016-08-16
AU2008329706A1 (en) 2009-06-04
ZA201003581B (en) 2011-07-27
EP2222168A1 (en) 2010-09-01
WO2009070687A1 (en) 2009-06-04
ES2693696T3 (es) 2018-12-13
AU2008329706B2 (en) 2013-01-10
EP2222168A4 (en) 2011-05-25
JP2011504934A (ja) 2011-02-17
DK2222168T3 (en) 2018-12-03
RU2497364C2 (ru) 2013-11-10
BRPI0819849B1 (pt) 2021-01-05

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