BRPI0820299A2 - Composições bucais estanosas - Google Patents

Composições bucais estanosas

Info

Publication number
BRPI0820299A2
BRPI0820299A2 BRPI0820299-0A2A BRPI0820299A BRPI0820299A2 BR PI0820299 A2 BRPI0820299 A2 BR PI0820299A2 BR PI0820299 A BRPI0820299 A BR PI0820299A BR PI0820299 A2 BRPI0820299 A2 BR PI0820299A2
Authority
BR
Brazil
Prior art keywords
ions
chelants
composition
zinc
divalent metal
Prior art date
Application number
BRPI0820299-0A2A
Other languages
English (en)
Inventor
Ross Strand
Maurice Joseph Prendergast
Xiaoli Wang
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BRPI0820299A2 publication Critical patent/BRPI0820299A2/pt
Publication of BRPI0820299B1 publication Critical patent/BRPI0820299B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BRPI0820299A 2007-11-09 2008-11-04 composições bucais estanosas BRPI0820299B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07120425 2007-11-09
PCT/IB2008/054595 WO2009060385A2 (en) 2007-11-09 2008-11-04 Oral stannous compositions

Publications (2)

Publication Number Publication Date
BRPI0820299A2 true BRPI0820299A2 (pt) 2014-09-30
BRPI0820299B1 BRPI0820299B1 (pt) 2016-07-26

Family

ID=39276045

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0820299A BRPI0820299B1 (pt) 2007-11-09 2008-11-04 composições bucais estanosas

Country Status (12)

Country Link
US (1) US8906347B2 (pt)
EP (1) EP2057978B1 (pt)
JP (1) JP5485160B2 (pt)
CN (2) CN101848694A (pt)
AT (1) ATE527978T1 (pt)
AU (1) AU2008326037B2 (pt)
BR (1) BRPI0820299B1 (pt)
CA (1) CA2703078C (pt)
ES (1) ES2375240T3 (pt)
MX (1) MX2010005130A (pt)
RU (1) RU2448680C2 (pt)
WO (1) WO2009060385A2 (pt)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100189663A1 (en) * 2009-01-24 2010-07-29 Gallis Karl W Mouth rinse compositions including chemically modified silica or silicate materials for sustained delivery to tooth surfaces
US20110236444A1 (en) * 2010-03-25 2011-09-29 Darsillo Michael S Antimicrobial Silica Composites
PL2552382T3 (pl) * 2010-03-31 2016-02-29 Colgate Palmolive Co Kompozycja do pielęgnacji jamy ustnej
EP2374446B1 (en) * 2010-04-07 2013-03-20 GABA International Holding AG Oral care composition comprising stannous and nitrate ions
CN104983593B (zh) * 2010-11-04 2018-11-20 高露洁-棕榄公司 涩味降低的洁齿组合物
AU2010363319B2 (en) 2010-11-04 2015-02-19 Colgate-Palmolive Company Dentifrice composition with reduced astringency
RU2013142576A (ru) * 2011-02-18 2015-05-10 Габа Интернациональ Холдинг Аг Композиция средства для чистки зубов
MX339909B (es) * 2011-07-12 2016-06-14 Procter & Gamble Composiciones para el cuidado bucal que comprende acido fitico.
MY166897A (en) * 2011-09-09 2018-07-24 Gaba Int Holding Ag Stable compositions and methods for preparing the same
CN104853715A (zh) * 2012-12-24 2015-08-19 高露洁-棕榄公司 口腔护理组合物
CN104721063B (zh) 2013-12-19 2018-05-08 高露洁-棕榄公司 包含氧化锌和柠檬酸锌的洁齿剂组合物
EP3082969B1 (en) * 2013-12-20 2019-08-28 Colgate-Palmolive Company Oral care compositions and methods
BR112016024176B1 (pt) * 2014-05-14 2020-12-08 The Procter & Gamble Company composições para tratamento bucal tendo estabilidade aprimorada
WO2015172348A1 (en) 2014-05-15 2015-11-19 The Procter & Gamble Company Dentifrice compositions having dental plaque mitigation or improved fluoride uptake
BR112016026338B1 (pt) 2014-05-15 2020-07-14 The Procter & Gamble Company Composições para tratamento bucal tendo refrescância aprimorada
CN106456459B (zh) 2014-05-15 2020-09-04 宝洁公司 包含聚乙二醇以提供物理稳定性的口腔护理组合物
BR112016025868B1 (pt) 2014-05-15 2020-06-30 The Procter & Gamble Company composições para tratamento bucal contendo polietilenoglicol para estabilidade física e método para tratamento do esmalte dental
PL3154503T3 (pl) 2014-05-15 2018-12-31 The Procter And Gamble Company Kompozycje środków do czyszczenia zębów ze optymalizowanymi środkami konserwującymi
WO2015172354A1 (en) 2014-05-15 2015-11-19 The Procter & Gamble Company Dentifrice compositions having improved fluoride ion stability or fluoride uptake
EP3157502B1 (en) * 2014-06-18 2018-11-28 Colgate-Palmolive Company Dentifrice comprising zinc - amino acid complex and phosphates
CA2952921C (en) 2014-06-20 2021-06-15 Colgate-Palmolive Company Oral compositions containing zinc, stannous and fluoride ion sources
CN107075555B (zh) * 2014-09-24 2021-12-03 高露洁-棕榄公司 金属离子的生物利用度
US12005076B2 (en) 2014-12-26 2024-06-11 Colgate-Palmolive Company Zinc phosphate complex
CN107106425B (zh) 2014-12-26 2021-01-22 高露洁-棕榄公司 具有磷酸锌活性物的个人护理组合物
AU2014415217B2 (en) * 2014-12-26 2018-11-29 Colgate-Palmolive Company Zinc phosphate complex
CA2971576A1 (en) 2014-12-26 2016-06-30 Colgate-Palmolive Company Zinc phosphate complex
MX376015B (es) 2014-12-26 2025-03-07 Colgate Palmolive Co Complejo de zinc y fosfato para el cuidado bucal.
US11135144B2 (en) 2014-12-26 2021-10-05 Colgate-Palmolive Company Low water dentifrice compositions
US10555883B2 (en) 2015-07-01 2020-02-11 Colgate-Palmolive Company Oral care compositions and methods of use
JP2015227361A (ja) * 2015-07-23 2015-12-17 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company 減少した収斂性を有する歯磨剤組成物
US10226407B2 (en) 2015-12-30 2019-03-12 Colgate-Palmolive Company Oral care compositions
AU2016380275C1 (en) 2015-12-30 2019-11-28 Colgate-Palmolive Company Oral care compositions
CN108472209B (zh) 2015-12-30 2021-06-25 高露洁-棕榄公司 个人护理组合物
CA3009800C (en) 2015-12-30 2024-01-16 Colgate-Palmolive Company Personal care composition comprising tin fluoride and pyrophosphate
AU2017281230B2 (en) 2016-06-24 2018-12-20 Colgate-Palmolive Company Oral care compositions and methods of using the compositions
AU2017281239B2 (en) 2016-06-24 2018-11-15 Colgate-Palmolive Company Oral care compositions
MX370965B (es) * 2016-06-24 2020-01-10 Colgate Palmolive Co Composiciones para el cuidado bucal y métodos de uso.
BR112018075975B1 (pt) 2016-06-24 2022-07-19 Colgate-Palmolive Company Composição para higiene bucal
CN109328092A (zh) 2016-06-24 2019-02-12 高露洁-棕榄公司 口腔护理组合物
CN109310592B (zh) 2016-06-24 2022-02-25 高露洁-棕榄公司 口腔护理组合物
BR112017019268A2 (pt) 2016-06-24 2018-07-17 Colgate-Palmolive Company composições para higiene bucal e métodos de uso.
MX388208B (es) 2016-12-21 2025-03-19 Colgate Palmolive Co Composiciones para el cuidado bucal y métodos de uso.
EP3541351B1 (en) 2016-12-21 2023-10-04 Colgate-Palmolive Company Oral care compositions
US10179098B2 (en) 2016-12-21 2019-01-15 Colgate-Palmolive Company Oral care compositions
CA3044403A1 (en) 2016-12-21 2018-06-28 Colgate-Palmolive Company Oral care compositions and methods of use
US10195128B2 (en) 2016-12-21 2019-02-05 Colgate-Palmolive Company Oral care compositions
WO2019216108A1 (ja) * 2018-05-10 2019-11-14 ライオン株式会社 口腔用組成物
US11369551B2 (en) 2018-12-04 2022-06-28 The Procter & Gamble Company Oral care compositions with improved tin compatability
US11135143B2 (en) 2020-06-25 2021-10-05 The Procter & Gamble Company Oral care compositions comprising tin ions
MX394508B (es) 2019-06-28 2025-03-24 Procter & Gamble Composiciones para el cuidado bucal que comprenden iones estaño
US12337048B2 (en) 2019-06-28 2025-06-24 The Procter & Gamble Company Oral care compositions comprising tin ions
CN114040741A (zh) 2019-06-28 2022-02-11 宝洁公司 包含锡离子的洁牙剂组合物
CN118370692A (zh) 2019-07-01 2024-07-23 高露洁-棕榄公司 口腔护理组合物和方法
CN114466643B (zh) * 2019-09-30 2024-01-26 宝洁公司 用于处理牙科生物膜的洁牙剂组合物
WO2021062621A1 (en) * 2019-09-30 2021-04-08 The Procter & Gamble Company Oral care compositions comprising stannous ion source, neutral amino acid, and polyphosphate
MX2022013038A (es) * 2020-05-05 2022-11-09 Procter & Gamble Composiciones para el cuidado bucal que comprenden acido dicarboxilico.
US20210346255A1 (en) * 2020-05-05 2021-11-11 The Procter & Gamble Company Oral Care Compositions Comprising Monodentate And Polydentate Ligand
US20210346259A1 (en) * 2020-05-05 2021-11-11 The Procter & Gamble Company Oral Care Compositions Comprising Dicarboxylic Acid
US20240050332A1 (en) * 2020-12-21 2024-02-15 Colgate-Palmolive Company Oral Care Compositions and Methods
WO2022140281A1 (en) * 2020-12-21 2022-06-30 Colgate-Palmolive Company Oral care compositions and methods
WO2022140368A1 (en) * 2020-12-21 2022-06-30 Colgate-Palmolive Company Oral care compositions comprising stannous pyrophosphate and a water-soluble alkali metal polyphosphate, and methods
CN117915883A (zh) 2021-08-23 2024-04-19 高露洁-棕榄公司 口腔护理组合物和方法
EP4331563A1 (en) * 2022-08-31 2024-03-06 Unilever IP Holdings B.V. Use of oral care composition
AU2024310612A1 (en) * 2023-06-28 2026-01-15 Colgate-Palmolive Company Oral care compositions
CN119792115A (zh) * 2025-02-10 2025-04-11 广州星际悦动股份有限公司 口腔护理组合物及其制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2946725A (en) 1957-03-25 1960-07-26 Procter & Gamble Dentifrice compositions
US3070510A (en) 1959-11-03 1962-12-25 Procter & Gamble Dentifrice containing resinous cleaning agents
US3282792A (en) 1964-01-09 1966-11-01 Bristol Myers Co Stabilized stannous fluoride dentifrice compositions
US3538230A (en) 1966-12-05 1970-11-03 Lever Brothers Ltd Oral compositions containing silica xerogels as cleaning and polishing agents
US3678154A (en) 1968-07-01 1972-07-18 Procter & Gamble Oral compositions for calculus retardation
US3535421A (en) 1968-07-11 1970-10-20 Procter & Gamble Oral compositions for calculus retardation
US3862307A (en) 1973-04-09 1975-01-21 Procter & Gamble Dentifrices containing a cationic therapeutic agent and improved silica abrasive
US4051234A (en) 1975-06-06 1977-09-27 The Procter & Gamble Company Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies
US4340583A (en) 1979-05-23 1982-07-20 J. M. Huber Corporation High fluoride compatibility dentifrice abrasives and compositions
JPS5846483B2 (ja) * 1979-09-20 1983-10-17 ライオン株式会社 口腔用組成物
US5004597A (en) 1987-09-14 1991-04-02 The Procter & Gamble Company Oral compositions comprising stannous flouride and stannous gluconate
GB8922434D0 (en) * 1989-10-05 1989-11-22 Unilever Plc Oral compositions
GB8922594D0 (en) * 1989-10-06 1989-11-22 Unilever Plc Oral compositions
US5213790A (en) 1991-10-23 1993-05-25 The Procter & Gamble Co. Methods of reducing plaque and gingivitis with reduced staining
US5300289A (en) * 1991-12-10 1994-04-05 The Dow Chemical Company Phytate antimicrobial compositions in oral care products
JPH08504816A (ja) 1992-12-18 1996-05-28 ザ、プロクター、エンド、ギャンブル、カンパニー 抗歯垢、抗歯石剤を含有した口内組成物
CZ156795A3 (en) 1992-12-18 1996-01-17 Procter & Gamble Mouth preparation containing agents against formation of microbial plaque, tartar, gingivitis and foetor ex ore
US5603920A (en) 1994-09-26 1997-02-18 The Proctor & Gamble Company Dentifrice compositions
US5578293A (en) 1994-12-06 1996-11-26 Colgate Palmolive Company Oral compositions containing stabilized stannous compounds having antiplaque and antitartar efficacy
US5658553A (en) 1995-05-02 1997-08-19 The Procter & Gamble Company Dentifrice compositions
US5651958A (en) 1995-05-02 1997-07-29 The Procter & Gamble Company Dentifrice compositions
US5589160A (en) 1995-05-02 1996-12-31 The Procter & Gamble Company Dentifrice compositions
GB9517031D0 (en) 1995-08-19 1995-10-25 Procter & Gamble Confection compositions
US20030206874A1 (en) * 1996-11-21 2003-11-06 The Proctor & Gamble Company Promoting whole body health
US6221340B1 (en) 1999-04-08 2001-04-24 Warner-Lambert Company Zinc containing dentifrice compositions
US6685920B2 (en) * 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
US20070025928A1 (en) * 1999-11-12 2007-02-01 The Procter & Gamble Company Stannous oral care compositions
MXPA02004787A (es) * 1999-11-12 2002-08-30 Procter & Gamble Composiciones bucales estanosas mejoradas.
ATE413209T1 (de) 2001-06-25 2008-11-15 Procter & Gamble Mundpflegezusammensetzungen
MXPA04005066A (es) * 2001-11-28 2004-08-19 Procter & Gamble Composiciones dentifricas que contienen una fase estable con bajo contenido de agua que comprende polifosfato e ingredientes activos ionicos.
AU2006331526A1 (en) * 2005-12-20 2007-07-05 The Procter & Gamble Company Oral care compositions comprising zinc and phytate
RU2493816C2 (ru) * 2006-04-07 2013-09-27 Дзе Проктер Энд Гэмбл Компани Способы и комплекты для ухода за полостью рта

Also Published As

Publication number Publication date
AU2008326037B2 (en) 2014-05-01
WO2009060385A2 (en) 2009-05-14
BRPI0820299B1 (pt) 2016-07-26
CN104784056A (zh) 2015-07-22
RU2010115240A (ru) 2011-12-20
WO2009060385A3 (en) 2009-07-30
AU2008326037A1 (en) 2009-05-14
CA2703078C (en) 2013-05-21
MX2010005130A (es) 2010-08-04
CA2703078A1 (en) 2009-05-14
EP2057978A1 (en) 2009-05-13
RU2448680C2 (ru) 2012-04-27
ATE527978T1 (de) 2011-10-15
ES2375240T3 (es) 2012-02-28
US8906347B2 (en) 2014-12-09
US20090136432A1 (en) 2009-05-28
JP2011500791A (ja) 2011-01-06
CN101848694A (zh) 2010-09-29
JP5485160B2 (ja) 2014-05-07
EP2057978B1 (en) 2011-10-12

Similar Documents

Publication Publication Date Title
ATE527978T1 (de) Orale zinnzusammensetzungen
ATE551988T1 (de) Orale zusammensetzungen, ihre herstellung und verwendung
ATE341367T1 (de) Mundpflegezusammensetzungen
TW200716519A (en) Benzoyl-substituted serineamides
PL2016940T3 (pl) Sposoby wytwarzania i zastosowanie kompozycji kompleksów chelatowych pirofosforanu (V) i cytrynianu z jonami żelaza (III)
MY158777A (en) Oral compositions containing polyguanidinium compounds and methods of manufacture and use thereof
BR0215517A (pt) Composição anti-séptica, e, métodos para desinfetar tecido e para produzir uma composição anti-séptica
BR112012011583A2 (pt) composições bucais para tratamento de boca seca
WO2011019342A3 (en) Oral care composition comprising a sesquiterpenoid and an antimicrobial agent
TW200734314A (en) Piperazine compounds having herbicidal action
TW200716558A (en) Heteroaroyl-substituted serineamides
MY142834A (en) Oxidation resistant dentifrice compositions
MY136917A (en) Use of polyphosphate as a tooth erosion inhibitors in acidic compositions
DE60109632D1 (de) Katechin und quercetin zur pharmazeutischen oder diätetischen verwendung
WO2009020010A1 (ja) 液体口腔用組成物、及びカチオン性殺菌剤の殺菌力向上方法
WO2007067559A3 (en) Antibacterial agents
TW200640532A (en) Oral compositions containing biphenol antibacterial compounds
RU2017120062A (ru) Композиции для ухода за полостью рта с высоким содержанием воды и высоким уровнем защиты от микроорганизмов
UA86984C2 (ru) Среднецепочные жирные кислоты как противомикробные средства
SG165326A1 (en) Compositions and methods to counteract oral malodour
EP2281547A3 (en) Tooth sensitivity treatment compositions
WO2007012080A3 (en) Oral care composition
EP2281548A3 (en) Tooth sensitivity treatment compositions
TW200744660A (en) Oral composition containing morin
WO2008001368A3 (en) Use of stilbene derivatives for treatment and prevention of aquatic mold infections

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/11/2008, OBSERVADAS AS CONDICOES LEGAIS.