BRPI0820707A2 - Métodos e composição para avaliar a responsividade do linfoma de células b para o tratamento com anticorpos anti-cd40 - Google Patents
Métodos e composição para avaliar a responsividade do linfoma de células b para o tratamento com anticorpos anti-cd40Info
- Publication number
- BRPI0820707A2 BRPI0820707A2 BRPI0820707-0A BRPI0820707A BRPI0820707A2 BR PI0820707 A2 BRPI0820707 A2 BR PI0820707A2 BR PI0820707 A BRPI0820707 A BR PI0820707A BR PI0820707 A2 BRPI0820707 A2 BR PI0820707A2
- Authority
- BR
- Brazil
- Prior art keywords
- responsiveness
- assessing
- composition
- methods
- cell lymphoma
- Prior art date
Links
- 208000003950 B-cell lymphoma Diseases 0.000 title 1
- 230000004043 responsiveness Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98627707P | 2007-11-07 | 2007-11-07 | |
| PCT/US2008/082920 WO2009062125A1 (en) | 2007-11-07 | 2008-11-07 | Methods and compositions for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0820707A2 true BRPI0820707A2 (pt) | 2015-06-16 |
Family
ID=40377361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820707-0A BRPI0820707A2 (pt) | 2007-11-07 | 2008-11-07 | Métodos e composição para avaliar a responsividade do linfoma de células b para o tratamento com anticorpos anti-cd40 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9068230B2 (pt) |
| EP (1) | EP2222875B1 (pt) |
| JP (2) | JP5730576B2 (pt) |
| KR (1) | KR101620642B1 (pt) |
| CN (1) | CN101910414B (pt) |
| AU (1) | AU2008323701B2 (pt) |
| BR (1) | BRPI0820707A2 (pt) |
| CA (1) | CA2704499C (pt) |
| IL (1) | IL205391A (pt) |
| MX (1) | MX2010005080A (pt) |
| WO (1) | WO2009062125A1 (pt) |
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| WO2009131365A2 (ko) * | 2008-04-21 | 2009-10-29 | 한국생명공학연구원 | 위암 진단 마커로서의 ｃst1, ｄcc1, ifitm1 또는 ｍelk |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| EP2364368B1 (en) | 2008-11-07 | 2014-01-15 | Sequenta, Inc. | Methods of monitoring conditions by sequence analysis |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| DK3059337T3 (da) | 2009-01-15 | 2019-07-22 | Adaptive Biotechnologies Corp | Adaptive immunity profiling og metoder til frembringelse af monoklonale antibodier |
| CA2758523C (en) | 2009-04-18 | 2019-03-12 | Genentech, Inc. | Methods for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies |
| RU2014144463A (ru) | 2009-06-25 | 2015-06-20 | Фред Хатчинсон Кансэр Рисёч Сентер | Способ измерения адаптивного иммунитета |
| EP2580348B1 (en) * | 2010-06-14 | 2018-04-25 | Qiagen GmbH | Method for determination of target cells or tissue for extraction of biomolecules from non-formalin-fixed biological samples |
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| US8592156B2 (en) * | 2011-08-08 | 2013-11-26 | Roche Molecular Systems, Inc. | Predicting response to anti-CD20 therapy in DLBCL patients |
| US20140356339A1 (en) * | 2011-09-09 | 2014-12-04 | Sequenta Inc. | Sequence-based measures of immune response |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| US9279159B2 (en) | 2011-10-21 | 2016-03-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| EP3388535B1 (en) | 2011-12-09 | 2021-03-24 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| DK2823060T3 (en) | 2012-03-05 | 2018-05-28 | Adaptive Biotechnologies Corp | Determination of associated immune receptor chains from frequency-matched subunits |
| EP3091089B1 (en) | 2012-05-08 | 2019-01-23 | Adaptive Biotechnologies Corporation | Method for measuring and calibrating amplification bias in multiplexed pcr reactions |
| US20160002731A1 (en) | 2012-10-01 | 2016-01-07 | Adaptive Biotechnologies Corporation | Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization |
| US10150996B2 (en) | 2012-10-19 | 2018-12-11 | Adaptive Biotechnologies Corp. | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| EP3066215B1 (en) | 2013-11-06 | 2019-04-24 | The United States of America, represented by the Secretary, Department of Health and Human Services | Method for subtyping lymphoma types by means of expression profiling |
| WO2015134787A2 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| MA39804A (fr) | 2014-03-27 | 2017-02-01 | Hoffmann La Roche | Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| CA2966201A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| HUE054075T2 (hu) | 2014-10-29 | 2021-08-30 | Seagen Inc | CD40 elleni nem fukozilált antitestek adagolása és bevitele |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| EP3224384A4 (en) | 2014-11-25 | 2018-04-18 | Adaptive Biotechnologies Corp. | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| US11047008B2 (en) | 2015-02-24 | 2021-06-29 | Adaptive Biotechnologies Corporation | Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing |
| WO2016161273A1 (en) | 2015-04-01 | 2016-10-06 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
| EP3329244B1 (en) | 2015-07-30 | 2022-10-05 | Qiagen GmbH | Method of preparing a frozen biological sample |
| DK3359688T3 (da) | 2015-10-05 | 2021-08-23 | Biogen Ma Inc | Molekylære signaturer til anvendelse til diagnose og analyse af respons på behandling af autoimmune sygdomme |
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| JP7461741B2 (ja) | 2016-06-20 | 2024-04-04 | カイマブ・リミテッド | 抗ｐｄ－ｌ１およびｉｌ－２サイトカイン |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| TWI704158B (zh) | 2017-04-04 | 2020-09-11 | 瑞士商赫孚孟拉羅股份公司 | 能夠特異性結合至cd40及fap之新穎雙特異性抗原結合分子 |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| US20240002941A1 (en) * | 2020-12-02 | 2024-01-04 | Albert Einstein College Of Medicine | Method for predicting patient response to cd40-targeted therapies |
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-
2008
- 2008-11-07 BR BRPI0820707-0A patent/BRPI0820707A2/pt not_active Application Discontinuation
- 2008-11-07 KR KR1020107012374A patent/KR101620642B1/ko active Active
- 2008-11-07 WO PCT/US2008/082920 patent/WO2009062125A1/en not_active Ceased
- 2008-11-07 US US12/741,814 patent/US9068230B2/en active Active
- 2008-11-07 JP JP2010533308A patent/JP5730576B2/ja active Active
- 2008-11-07 AU AU2008323701A patent/AU2008323701B2/en active Active
- 2008-11-07 MX MX2010005080A patent/MX2010005080A/es active IP Right Grant
- 2008-11-07 EP EP08848388.8A patent/EP2222875B1/en active Active
- 2008-11-07 CN CN200880124201.5A patent/CN101910414B/zh active Active
- 2008-11-07 CA CA2704499A patent/CA2704499C/en active Active
-
2010
- 2010-04-28 IL IL205391A patent/IL205391A/en active IP Right Grant
-
2013
- 2013-10-09 JP JP2013211645A patent/JP2014057588A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2704499C (en) | 2020-03-10 |
| JP2011504102A (ja) | 2011-02-03 |
| EP2222875B1 (en) | 2014-08-20 |
| CA2704499A1 (en) | 2009-05-14 |
| MX2010005080A (es) | 2010-07-28 |
| IL205391A0 (en) | 2010-12-30 |
| KR101620642B1 (ko) | 2016-05-12 |
| EP2222875A1 (en) | 2010-09-01 |
| US9068230B2 (en) | 2015-06-30 |
| AU2008323701B2 (en) | 2015-03-26 |
| CN101910414B (zh) | 2016-01-13 |
| CN101910414A (zh) | 2010-12-08 |
| JP2014057588A (ja) | 2014-04-03 |
| US20110104671A1 (en) | 2011-05-05 |
| IL205391A (en) | 2015-08-31 |
| AU2008323701A1 (en) | 2009-05-14 |
| JP5730576B2 (ja) | 2015-06-10 |
| WO2009062125A1 (en) | 2009-05-14 |
| KR20100095564A (ko) | 2010-08-31 |
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