BRPI0820888A2 - Quaternização do copolímero aditivo metacrilato de aminoalquila e para melhorar a permeabilidade e a solubilidade de produtos farmacêuticos. - Google Patents

Quaternização do copolímero aditivo metacrilato de aminoalquila e para melhorar a permeabilidade e a solubilidade de produtos farmacêuticos.

Info

Publication number: BRPI0820888A2
Authority: BR; Brazil
Prior art keywords: quaternization; pharmaceuticals; permeability; solubility; improve
Prior art date: 2007-12-13

Application number

BRPI0820888-3A

Other languages

English (en)

Inventor

Peter Langguth

Stefan Grube

Holger Frey

Boris Obermeier

Original Assignee

Evonik Roehm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-13

Filing date

2008-12-12

Publication date

2015-06-16

2008-12-12 Application filed by Evonik Roehm Gmbh filed Critical Evonik Roehm Gmbh

2015-06-16 Publication of BRPI0820888A2 publication Critical patent/BRPI0820888A2/pt

2019-03-26 Publication of BRPI0820888B1 publication Critical patent/BRPI0820888B1/pt

2022-07-05 Publication of BRPI0820888B8 publication Critical patent/BRPI0820888B8/pt

Links

239000000654 additive Substances 0.000 title 1
230000000996 additive effect Effects 0.000 title 1
-1 aminoalkyl methacrylate Chemical compound 0.000 title 1
229920001577 copolymer Polymers 0.000 title 1
239000003814 drug Substances 0.000 title 1
230000035699 permeability Effects 0.000 title 1
238000005956 quaternization reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F26/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F26/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Polymers & Plastics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BRPI0820888A 2007-12-13 2008-12-12 Copolímero de metacrilato de aminoalquila e, seu uso e seu método de produção, e formulação farmacêutica BRPI0820888B8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE102007060175.3		2007-12-13
DE102007060175A DE102007060175A1 (de)	2007-12-13	2007-12-13	Quartärnisierung des Zusatzstoffs Aminoalkyl Methacrylat Copolymer E zur Verbesserung der Permeabilität und Löslichkeit von Arzneistoffen
PCT/EP2008/010585 WO2009074336A1 (de)	2007-12-13	2008-12-12	Quartärnisierung des zusatzstoffs aminoalkyl methacrylat copolymer e zur verbesserung der permeabilität und löslichkeit von arzneistoffen

Publications (3)

Publication Number	Publication Date
BRPI0820888A2 true BRPI0820888A2 (pt)	2015-06-16
BRPI0820888B1 BRPI0820888B1 (pt)	2019-03-26
BRPI0820888B8 BRPI0820888B8 (pt)	2022-07-05

Family

ID=40339608

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0820888A BRPI0820888B8 (pt)	2007-12-13	2008-12-12	Copolímero de metacrilato de aminoalquila e, seu uso e seu método de produção, e formulação farmacêutica

Country Status (15)

Country	Link
US (1)	US8399523B2 (pt)
EP (1)	EP2219676B1 (pt)
JP (1)	JP5645668B2 (pt)
KR (1)	KR101573554B1 (pt)
CN (2)	CN103897079B (pt)
BR (1)	BRPI0820888B8 (pt)
CA (1)	CA2708431C (pt)
DE (1)	DE102007060175A1 (pt)
ES (1)	ES2562444T3 (pt)
HU (1)	HUE026739T2 (pt)
IL (1)	IL206016A (pt)
MX (1)	MX2010006354A (pt)
PL (1)	PL2219676T3 (pt)
SI (1)	SI2219676T1 (pt)
WO (1)	WO2009074336A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102470175B (zh) *	2009-07-30	2014-06-18	赢创罗姆有限公司	含氨基(甲基)丙烯酸酯聚合物或共聚物的水性碳酸化介质
EP3916029A1 (en)	2020-05-28	2021-12-01	Evonik Operations GmbH	Novel methacrylate copolymer and compositions comprising it
EP3915543A1 (en)	2020-05-28	2021-12-01	Evonik Operations GmbH	Solid self-nanoemulsifying drug delivery system (s-snedds)
CA3203975A1 (en)	2020-12-03	2022-06-09	Battelle Memorial Institute	Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
CA3216359A1 (en)	2021-04-07	2022-10-13	Battelle Memorial Institute	Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
AU2024353375A1 (en)	2023-09-29	2026-04-09	Battelle Memorial Institute	Polymer nanoparticle compositions for in vivo expression of polypeptides
WO2025122954A1 (en)	2023-12-08	2025-06-12	Battelle Memorial Institute	Use of dna origami nanostructures for molecular information based data storage systems

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US4179549A (en) *	1974-11-14	1979-12-18	Petrolite Corporation	Quaternary ammonium adducts of polymerizable tertiary ammonium salts and acrylamide
JPS61174202A (ja) *	1985-01-29	1986-08-05	Mitsubishi Yuka Fine Chem Co Ltd	水溶性の感光性樹脂の製造方法
JPH075683B2 (ja) *	1986-09-09	1995-01-25	三菱レイヨン株式会社	帯電防止性に優れたメタクリル樹脂キヤスト板の製造方法
JP2520659B2 (ja) *	1987-09-10	1996-07-31	東京瓦斯株式会社	センサ―架台の海底着座方法及び装置
ES2188657T3 (es) *	1994-04-22	2003-07-01	Yamanouchi Pharma Co Ltd	Sistema para la liberacion especifica en el colon de un farmaco.
DE69728778D1 (de) *	1996-09-19	2004-05-27	Procter & Gamble	Weichspüler mit verbesserter leistung
IT1294748B1 (it)	1997-09-17	1999-04-12	Permatec Tech Ag	Formulazione per un dispositivo transdermico
FR2804122B1 (fr) *	2000-01-24	2002-02-22	Atofina	Dispersions aqueuses sans sel de (co)polymeres hydrosolubles a base de monomeres cationiques, leur procede de fabrication et leurs applications
DE10013029A1 (de) *	2000-03-17	2001-09-20	Roehm Gmbh	Mehrschichtige Arzneiform für die Colonfreigabe
CA2415643C (en)	2000-07-17	2010-11-16	Yamanouchi Pharmaceutical Co., Ltd.	Pharmaceutical composition for oral use with improved absorption
US20050019381A1 (en) *	2001-01-29	2005-01-27	Hans-Ulrich Petereit	Binding agent which is stable in storage and used for pharmaceutical applications
GB0114197D0 (en)	2001-06-11	2001-08-01	Syngenta Ltd	Reactive polymeric surfactants
US20030095928A1 (en) *	2001-09-19	2003-05-22	Elan Pharma International Limited	Nanoparticulate insulin
US6838078B2 (en) *	2002-01-16	2005-01-04	3M Innovative Properties Company	Film-forming compositions and methods
GB0228537D0 (en) *	2002-12-06	2003-01-15	Syngenta Ltd	Particulate suspensions
GB0229147D0 (en) *	2002-12-13	2003-01-15	Unilever Plc	Polymers and laundry detergent compositions containing them
US7087174B2 (en) *	2004-04-08	2006-08-08	Nalco Company	Enhanced recovery of useful coal, potassium chloride and borax from screen bowl centrifuge
JP4362093B2 (ja) *	2004-08-06	2009-11-11	大日本印刷株式会社	帯電防止膜形成用の電離放射線硬化性組成物と帯電防止膜および帯電防止膜を備えた構造体
JP2006161259A (ja) *	2004-11-12	2006-06-22	Harima Chem Inc	カチオン性表面サイズ剤、及び当該サイズ剤を塗工した紙
EP1810668A1 (en)	2006-01-23	2007-07-25	LEK Pharmaceuticals D.D.	Coated formulations containing tolterodine tartrate

2007
- 2007-12-13 DE DE102007060175A patent/DE102007060175A1/de not_active Withdrawn
2008
- 2008-12-12 BR BRPI0820888A patent/BRPI0820888B8/pt not_active IP Right Cessation
- 2008-12-12 CA CA2708431A patent/CA2708431C/en active Active
- 2008-12-12 JP JP2010537322A patent/JP5645668B2/ja not_active Expired - Fee Related
- 2008-12-12 WO PCT/EP2008/010585 patent/WO2009074336A1/de not_active Ceased
- 2008-12-12 MX MX2010006354A patent/MX2010006354A/es active IP Right Grant
- 2008-12-12 KR KR1020107012907A patent/KR101573554B1/ko not_active Expired - Fee Related
- 2008-12-12 ES ES08860544.9T patent/ES2562444T3/es active Active
- 2008-12-12 CN CN201410112390.1A patent/CN103897079B/zh not_active Expired - Fee Related
- 2008-12-12 PL PL08860544T patent/PL2219676T3/pl unknown
- 2008-12-12 US US12/747,722 patent/US8399523B2/en not_active Expired - Fee Related
- 2008-12-12 EP EP08860544.9A patent/EP2219676B1/de active Active
- 2008-12-12 SI SI200831579T patent/SI2219676T1/sl unknown
- 2008-12-12 CN CN2008801208052A patent/CN101896207A/zh active Pending
- 2008-12-12 HU HUE08860544A patent/HUE026739T2/en unknown
2010
- 2010-05-27 IL IL206016A patent/IL206016A/en active IP Right Grant

Also Published As

Publication number	Publication date
KR20100106380A (ko)	2010-10-01
ES2562444T3 (es)	2016-03-04
JP2011506370A (ja)	2011-03-03
PL2219676T3 (pl)	2016-05-31
BRPI0820888B8 (pt)	2022-07-05
EP2219676B1 (de)	2015-12-09
CA2708431A1 (en)	2009-06-18
CN101896207A (zh)	2010-11-24
US20100286288A1 (en)	2010-11-11
BRPI0820888B1 (pt)	2019-03-26
JP5645668B2 (ja)	2014-12-24
IL206016A0 (en)	2010-11-30
DE102007060175A1 (de)	2009-06-18
EP2219676A1 (de)	2010-08-25
SI2219676T1 (sl)	2016-03-31
HUE026739T2 (en)	2016-07-28
KR101573554B1 (ko)	2015-12-01
CN103897079B (zh)	2017-08-18
CA2708431C (en)	2016-01-26
US8399523B2 (en)	2013-03-19
CN103897079A (zh)	2014-07-02
MX2010006354A (es)	2010-12-20
WO2009074336A1 (de)	2009-06-18
IL206016A (en)	2015-11-30

Legal Events

Date	Code	Title	Description
2017-10-24	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-06-19	B07G	Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
2018-08-14	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2019-02-05	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2019-03-26	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/03/2019, OBSERVADAS AS CONDICOES LEGAIS.
2022-05-24	B25D	Requested change of name of applicant approved	Owner name: ROEHM GMBH (DE)
2022-06-07	B25G	Requested change of headquarter approved	Owner name: ROEHM GMBH (DE)
2022-06-21	B25A	Requested transfer of rights approved	Owner name: EVONIK DEGUSSA GMBH (DE)
2022-07-05	B25D	Requested change of name of applicant approved	Owner name: EVONIK OPERATIONS GMBH (DE)
2024-10-08	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 16A ANUIDADE.
2025-02-04	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2805 DE 08-10-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
NL300891I2 (nl)	2017-11-21	Lotilaner en zouten daarvan
DE602008001431D1 (de)	2010-07-15	Lösliche Polythiophenderivate
EP2511268A4 (en)	2013-04-17	oxazine
BRPI1013023A2 (pt)	2016-03-29	"bolsa solúvel em água"
BRPI0716253A2 (pt)	2013-09-24	glioxalaÇço de polÍmero de vinilamida
DE602006008264D1 (de)	2009-09-17	Turbo-Auflader
BRPI0907064A2 (pt)	2015-07-07	"métodos e sistemas"
EP2037942A4 (en)	2012-04-25	POLYMER biosurfactants
DK1973775T3 (da)	2014-08-11	Bølgeenergi
DE602007011183D1 (de)	2011-01-27	Hydrazinfunktionalisiertes Polymer
HRP20141261T1 (xx)	2015-03-13	Spojevi tioninija i njihove uporabe
BRPI0717235A2 (pt)	2013-10-08	Dispositivo para pig
DK2215308T3 (da)	2011-08-15	Højvandsklap
EP2023715A4 (en)	2009-11-18	Indoleamine-2,3-dioxygenase 2
DE502007001779D1 (de)	2009-12-03	Anhängekupplung
BRPI0817802A2 (pt)	2015-04-07	Dispersões aquosas
BRPI0820888A2 (pt)	2015-06-16	Quaternização do copolímero aditivo metacrilato de aminoalquila e para melhorar a permeabilidade e a solubilidade de produtos farmacêuticos.
DK2193795T3 (da)	2014-11-03	Latanoprostholdig vandig farmaceutisk sammensætning
EP2184303A4 (en)	2011-01-12	Copolymer
FR22C1045I2 (fr)	2023-12-29	Conjugués protéine-polymère
EP3318555C0 (en)	2023-08-16	BIFUNCTIONAL CHELATING AGENTS
EP2484973A4 (en)	2013-03-13	detonator
EP2204178A4 (en)	2010-11-24	LAXATIVE
IT1398018B1 (it)	2013-02-04	Obice rimorchiato
FI20065612A0 (fi)	2006-09-29	Sivurajoitin