BRPI0820953A2 - Métodos para preparar um composto e uma composição - Google Patents

Métodos para preparar um composto e uma composição

Info

Publication number
BRPI0820953A2
BRPI0820953A2 BRPI0820953-7A BRPI0820953A BRPI0820953A2 BR PI0820953 A2 BRPI0820953 A2 BR PI0820953A2 BR PI0820953 A BRPI0820953 A BR PI0820953A BR PI0820953 A2 BRPI0820953 A2 BR PI0820953A2
Authority
BR
Brazil
Prior art keywords
preparing
compound
composition
methods
Prior art date
Application number
BRPI0820953-7A
Other languages
English (en)
Inventor
Roch Boivin
Silvio A Campagna
Hong Du
Francis G Fang
Thomas Horstmann
Charles-Andre Lemelin
Jing Li
Pamela Mcguinness
Xiang Niu
Matthew J Schnaderbeck
Kevin Kuo-Ming Wu
Xiaojie Jeff Zhu
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of BRPI0820953A2 publication Critical patent/BRPI0820953A2/pt
Publication of BRPI0820953B1 publication Critical patent/BRPI0820953B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/081,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
BRPI0820953-7A 2007-12-07 2008-12-08 Métodos para preparar um composto e uma composição BRPI0820953B1 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US1241107P 2007-12-07 2007-12-07
US1240807P 2007-12-07 2007-12-07
US1240907P 2007-12-07 2007-12-07
US61/012408 2007-12-07
US61/012409 2007-12-07
US61/012411 2007-12-07
US8004808P 2008-07-11 2008-07-11
US61/080048 2008-07-11
PCT/US2008/013498 WO2009075818A1 (en) 2007-12-07 2008-12-08 Intermediates and methods for making zearalenone macrolide analogs

Publications (2)

Publication Number Publication Date
BRPI0820953A2 true BRPI0820953A2 (pt) 2015-06-23
BRPI0820953B1 BRPI0820953B1 (pt) 2022-04-05

Family

ID=40445478

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0820953-7A BRPI0820953B1 (pt) 2007-12-07 2008-12-08 Métodos para preparar um composto e uma composição
BRPI0820958-8A BRPI0820958B1 (pt) 2007-12-07 2008-12-08 Compostos macrolídeos

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0820958-8A BRPI0820958B1 (pt) 2007-12-07 2008-12-08 Compostos macrolídeos

Country Status (10)

Country Link
US (3) US8350059B2 (pt)
EP (2) EP2231635B1 (pt)
JP (3) JP5496908B2 (pt)
CN (2) CN101889006B (pt)
BR (2) BRPI0820953B1 (pt)
CA (2) CA2708141C (pt)
IL (2) IL205954A (pt)
MX (2) MX2010006091A (pt)
RU (2) RU2478630C2 (pt)
WO (2) WO2009075818A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076424A1 (en) 2002-03-08 2003-09-18 Eisai Co. Ltd. Macrocyclic compounds useful as pharmaceuticals
ES2670423T3 (es) 2007-07-25 2018-05-30 Eisai R&D Management Co., Ltd. Inhibidores de multicinasas para uso en el tratamiento de cáncer
RU2478630C2 (ru) * 2007-12-07 2013-04-10 ЭЙСАН Ар ЭНД Ди МЕНЕДЖМЕНТ КО., ЛТД. Промежуточные соединения и способы получения зеараленоновых макролидных аналогов

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU561147B2 (en) * 1982-09-13 1987-04-30 Eli Lilly And Company 20-amino macrolide antibiotics
GB9225396D0 (en) 1992-12-04 1993-01-27 Sandoz Ltd Improvements in or relating to organic compounds
US5795910A (en) 1994-10-28 1998-08-18 Cor Therapeutics, Inc. Method and compositions for inhibiting protein kinases
SK286592B6 (sk) * 1997-07-08 2009-01-07 Bristol-Myers Squibb Company Derivát epotilónu, farmaceutický prostriedok s jeho obsahom a jeho použitie
JP2004292314A (ja) 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd ケラチノサイト増殖抑制剤
JP2004292315A (ja) 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd Tak1阻害剤
US7915306B2 (en) * 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
WO2003076424A1 (en) 2002-03-08 2003-09-18 Eisai Co. Ltd. Macrocyclic compounds useful as pharmaceuticals
CA2696021C (en) 2006-08-11 2015-09-29 Nicolas Winssinger Macrocyclic compounds useful as inhibitors of kinases and hsp90
WO2008149244A2 (en) * 2007-06-05 2008-12-11 Nicolas Winssinger Compositions and methods comprising analogues of radicicol a
ES2670423T3 (es) 2007-07-25 2018-05-30 Eisai R&D Management Co., Ltd. Inhibidores de multicinasas para uso en el tratamiento de cáncer
TW200924749A (en) * 2007-07-25 2009-06-16 Eisai R & Amp D Man Co Ltd Zearalenone macrolide derivatives and uses of the same
RU2478630C2 (ru) * 2007-12-07 2013-04-10 ЭЙСАН Ар ЭНД Ди МЕНЕДЖМЕНТ КО., ЛТД. Промежуточные соединения и способы получения зеараленоновых макролидных аналогов

Also Published As

Publication number Publication date
EP2231635B1 (en) 2014-03-19
RU2497803C2 (ru) 2013-11-10
US20110046398A1 (en) 2011-02-24
IL205983A (en) 2017-01-31
US8507696B2 (en) 2013-08-13
EP2231635A1 (en) 2010-09-29
BRPI0820958B1 (pt) 2022-04-05
JP5492786B2 (ja) 2014-05-14
MX2010005999A (es) 2010-06-23
US20110237805A1 (en) 2011-09-29
US20130211103A1 (en) 2013-08-15
CA2708141C (en) 2016-07-05
JP5496908B2 (ja) 2014-05-21
US8350059B2 (en) 2013-01-08
BRPI0820958A2 (pt) 2015-07-07
CA2708143C (en) 2016-10-11
CA2708141A1 (en) 2009-06-18
CA2708143A1 (en) 2009-06-18
BRPI0820953B1 (pt) 2022-04-05
RU2010128096A (ru) 2012-01-20
CN101889005B (zh) 2015-06-03
WO2009075818A1 (en) 2009-06-18
JP2011506324A (ja) 2011-03-03
RU2478630C2 (ru) 2013-04-10
RU2010128103A (ru) 2012-01-20
EP2231634A1 (en) 2010-09-29
IL205983A0 (en) 2010-11-30
CN101889006B (zh) 2013-09-04
CN101889005A (zh) 2010-11-17
IL205954A (en) 2017-01-31
MX2010006091A (es) 2010-06-25
IL205954A0 (en) 2010-11-30
WO2009075823A1 (en) 2009-06-18
JP2014141498A (ja) 2014-08-07
CN101889006A (zh) 2010-11-17
JP2011506323A (ja) 2011-03-03
EP2231634B1 (en) 2016-05-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07D 313/00 , C07D 317/22 , C07D 317/24 , C07D 493/04 , C07C 69/767 , C07D 319/08

Ipc: C07D 313/00 (2006.01), C07D 317/22 (2006.01), C07D

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/12/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.